35 research outputs found
A contingent valuation study of buriti ( Mauritia flexuosa L.f.) in the main region of production in Brazil: is environmental conservation a collective responsibility?
Growth and Asymmetry of Soil Microfungal Colonies from âEvolution Canyon,â Lower Nahal Oren, Mount Carmel, Israel
Fluctuating asymmetry is a contentious indicator of stress in populations of animals and plants. Nevertheless, it is a measure of developmental noise, typically obtained by measuring asymmetry across an individual organism's left-right axis of symmetry. These individual, signed asymmetries are symmetrically distributed around a mean of zero. Fluctuating asymmetry, however, has rarely been studied in microorganisms, and never in fungi.We examined colony growth and random phenotypic variation of five soil microfungal species isolated from the opposing slopes of âEvolution Canyon,â Mount Carmel, Israel. This canyon provides an opportunity to study diverse taxa inhabiting a single microsite, under different kinds and intensities of abiotic and biotic stress. The south-facing âAfricanâ slope of âEvolution Canyonâ is xeric, warm, and tropical. It is only 200 m, on average, from the north-facing âEuropeanâ slope, which is mesic, cool, and temperate. Five fungal species inhabiting both the south-facing âAfricanâ slope, and the north-facing âEuropeanâ slope of the canyon were grown under controlled laboratory conditions, where we measured the fluctuating radial asymmetry and sizes of their colonies. from the âAfricanâ slope were more asymmetric than those from the âEuropeanâ slope.Our study suggests that fluctuating radial asymmetry has potential as an indicator of random phenotypic variation and stress in soil microfungi. Interaction of slope and species for both growth rate and asymmetry of microfungi in a common environment is evidence of genetic differences between the âAfricanâ and âEuropeanâ slopes of âEvolution Canyon.
Mental health problems among medical students in Brazil: a systematic review and meta-analysis
Padronização de condiçÔes para detecção de DNA de Leishmania spp. em flebotomĂneos (Diptera, Psychodidae) pela reação em cadeia da polimerase
Sarcoidosis of the central nervous system: Safety and efficacy of treatment, and experience of biological therapies
Characterization of nutritionally important phytoconstituents in minimally processed ready-to-eat baby-leaf vegetables using HPLCâDAD and GCâMS
Therapeutic trial in experimental tegumentary leishmaniasis caused by Leishmania (Leishmania) amazonensis. A comparative study between mefloquine and aminosidine Ensaio terapĂȘutico na leishmaniose tegumentar experimental causada por Leishmania (Leishmania) amazonensis. Um estudo comparativo entre mefloquina e aminosidine
One hundred and eighty-two male inbred C57/BL/6 mice were infected with 3 x 106 Leishmania (Leishmania) amazonensis promastigotes of the MHOM/BR/PH8 strain by means of a subcutaneous injection in the right ear. The animals were separated in three groups: 1) oral mefloquine hydrochloride treatment (16mg/kg/day/10 days), 2) intramuscular aminosidine (ParomomycinÂź) treatment (20mg/kg/20 days) and 3) control. Twenty six mice of each treated group were sacrificed, one at the end of treatment (nine weeks after inoculation), and one six weeks later (fifteen weeks after inoculation). Control Group animals were sacrificed at weeks six, nine and fifteen after inoculation. There was no significant difference between Group 1 (mefloquine) and Group 3 (control) subjects. Group 2 animals (aminosidine) presented the smallest differences of all, both at the end of the treatment and six weeks later. The histopato-logical parameters have shown the following findings: a) there was no significant difference between the mefloquine treated group and the control group; the group treated with aminosidine showed fewer of vacuolated macrophages than the control group, at week 9 (end of treatment). b) both at the end of treatment and six weeks later, evaluation of tissue necrosis and tissue fibrosis revealed no differences between the treated groups. It was found that six weeks after the end of treatment, mice in the control group presented significantly more severe degrees of fibrosis than mice in the other groups. It can be concluded that mefloquine showed limited therapeutic effect in this experimental model, whereas aminosidine had a significant effect. Nevertheless, neither of them resulted in cure of the lesions.<br>Foram utilizados 182 camundongos machos, isogĂȘnicos, da linhagem C57BL/6 inoculados na orelha direita com 3,0 x 10(6) formas promastigotas da cepa MHOM/BR/PH8 de Leishmania (Leishmania) amazonensis. Os animais foram separados em trĂȘs grupos: 1) 52 animais tratados com mefloquina (16mg/kg/dia/10 dias), 2) 52 animais tratados com aminosidina [Paramomicina Âź] (20mg/kg/dia/20 dias), 3) 78 animais controles, nĂŁo manipulados. Vinte e seis animais de cada grupo tratado foram sacrificados nove e quinze semanas apĂłs a inoculação. Animais do grupo controle foram sacrificados na sexta, nona e dĂ©cima quinta semanas apĂłs a inoculação. Ao final do tratamento, em relação Ă curva de peso da orelhas, somente nos animais tratados com aminosidina, houve nĂtida redução do peso em comparação com grupo controle. Na histopatologia verificou-se: a) nĂŁo houve diferença entre o grupo tratado com mefloquina e o grupo controle; o grupo tratado com aminosidina, ao final do tratamento, teve menor infiltração por macrĂłfagos vacuolizados; b) as avaliaçÔes da extensĂŁo das ĂĄreas de necrose e do nĂvel da fibrose tecidual nĂŁo mostraram diferenças entre os grupos tratados. Os animais do grupo controle apresentaram fibrose mais acentuada, seis semanas apĂłs o fim do tratamento. Pode-se concluir que ocorreu efeito terapĂȘutico reduzido com a mefloquina e houve significativa melhora com a aminosidina. Entretanto, em todos os grupos as lesĂ”es nĂŁo chegaram a curar