PEDAGOGIAS EXPRESSIVAS NA FORMACÃO DE PROFESSORES

Este trabalho apresenta um excerto da experi^ encia das autoras na formac ~ ao de professores, em Portugal, em dois ^ambitos pr oximos, mas distintos: (a) na utilizac ~ ao das Pedagogias Expressivas enquanto metodologia de ensino na formac ~ ao de professores, e (b) no ensino das Pedagogias Expressivas para que possam ser utilizadas pelos professores nos seus contextos de atuac ~ ao profissional, tendo sempre como pano de fundo a Educac ~ ao Inclusiva. Num percurso de mais de 15 anos de atuac ~ ao, e not avel a difus~ao das Pedagogias Expressivas em diversos cursos de formac ~ ao inicial e contínua de professores (embora o título possa variar). Constata-se, igualmente, um interesse cada vez maior pela aquisic ~ ao e desenvolvimento de saberes e compet^encias nesta area, dado o n umero crescente de professores que realizam formac ~ ao neste ^ambito, bem como a proliferac ~ ao de currículos que passaram a contemplar estas pedagogias tanto como Unidades Curriculares (Disciplinas, antes do Processo de Bolonha), como enquanto conte udo program atico de Unidades Curriculares com nomenclaturas diversas. Esperamos que a experi^encia relatada em forma de exemplos, dentro de uma perspetiva de desenvolvimento profissional, possa servir como reflex~ao crítica, como confirmac ~ ao ou como inspirac ~ ao para a adoc ~ ao de metodologias cada vez mais expressivas, cooperativas e, idealmente, mais inclusivas

Immunization with rP22 induces protective immunity against Schistosoma mansoni: Effects on granuloma down-modulation and cytokine production

AbstractSchistosomiasis remains a significant public health problem in tropical countries and it is recognized as the most important human helminth infection in terms of morbidity and mortality. Although the existing antischistosomal drugs are highly effective, they do not prevent against reinfection or granuloma formation. Therefore, vaccine strategies are essential for the control of schistosomiasis. Our group recently identified the recombinant (r) P22 protein, a component of the adult worm protein fraction PIII that has been shown to engender protective and immunomodulatory effects on murine schistosomiasis. A cDNA clone encoding rP22 was isolated from a Schistosoma mansoni adult worm cDNA library using anti-PIII rabbit serum; it exhibited complete identity with S. mansoni Sm21.7 EF-hand antigen. Confocal microscopy revealed that rP22 is a tegument protein localized on the surface of S. mansoni miracidia and adult worms. Mice immunized with rP22 exhibited a 51% and 22.5% decrease in adult worm burden and in hepatic eggs, respectively. Additionally, rP22 vaccine produced a reduction in 60% of liver granuloma size and 71% of fibrosis in mice, suggesting that rP22 might contribute to down-modulate granulomatous hypersensitivity to S. mansoni eggs. Protective immunity in mice was associated with high titers of rP22-specific IgG antibodies; elevated production of IFN-γ, TNF-α and IL-10; and a reduced level of IL-4. In conclusion, these findings indicate that rP22-based vaccines could be useful to elicit protection and reduce pathology associated to schistosomiasis

Fatores de risco cardiovascular e distribuição de gordura corporal em brasileiros com 80 anos ou mais

Modelo do estudo: Estudo transversal. Objetivo: Analisar a presença de fatores de risco cardiovascular (FRC) de acordo com o padrão de distribuição de gordura corporal em brasileiros com 80 anos ou mais. Materiais e Método: A amostra foi composta de 113 idosos, com média de idade de 83,4 anos, de ambos os sexos. O percentual de gordura corporal total e abdominal, hipertensão e perfil lipídico foram usados para caracterização dos FRC. O teste qui-quadrado foi utilizado para avaliação das proporções de FRC e o teste Mann-Whitney foi utilizado para comparar os resultados de adiposidade. Resultados: Idosos eutróficos apresentaram baixo triglicerídeos (p=0,017) e colesterol total (p=0,001) além de menores prevalências de hipertensão (p=0,003) e hipertrigliceridemia (p=0,007). Idosos com maior adiposidade abdominal apresentaram maior colesterol total (p=0,026) e prevalência de hipertrigliceridemia (p=0,011) e hipercolesterolemia (p=0,026) quando comparados com os de menor adiposidade abdominal. Aqueles com excesso de gordura (total, ou abdominal ou ambos), com exceção da glicemia (p=0,877), apresentaram alta prevalência de FRC. Aqueles com ambos os excessos de gordura apresentam diferenças, com maior nível de prevalência quando comparados aqueles com apenas um ou nenhum dos excessos. Conclusão: A obesidade, sendo abdominal ou total, é associada, da mesma maneira, com FRC em sujeitos com 80 anos ou maisStudy design: Cross-sectional study. Objective: To analyze the presence of cardiovascular risk factors (CRFs) according to the pattern of body fat distribution, in Brazilians aged 80 years or over. Methods: The sample consisted of 113 subjects, of 83.4 years, of both sexes. The percentages of total and abdominal body fat, hypertension and lipid profile were used for characterization of CRFs. The chisquare test was used to assess proportions of CRFs and the Mann-Whitney test was used to compare the results of adiposity. Results: Eutrophic subjects presented lower triglycerides (p=0.017), total cholesterol (p=0.001) and prevalence of both hypertension (p=0.003) and hypertriglyceridemia (p=0.007). Subjects with higher abdominal adiposity presented higher total cholesterol (p=0.026) and prevalence of hypertriglyceridemia (p=0.011) and hypercholesterolemia (p=0.026) than those with no excess abdominal adiposity. Those with excess fat (total, abdominal or both), with the exception of glucose (p=0.877), presented a high prevalence of CRFs. Those with both types of excess fat presented differences, with a higher prevalence level when compared to those with only one or neither of the excesses. Conclusion: Obesity, whether abdominal or total, is similarly associated with CRFs in subjects aged 80 years and ove

OUT to IN: Efeitos de um programa de intervenção psicomotora na autorregulação de crianças em idade pré-escolar

A autorregulação na idade pré-escolar é preditora do bem-estar e do sucesso pessoal e social na vida adulta. O programa OUT to IN propõe uma abordagem de mediação corporal implementada no espaço exterior do jardim de infância com o objetivo de melhorar as competências sócio-emocionais. Este estudo tem como objetivo examinar o impacto do OUT to IN, na autorregulação de crianças em idade pré-escolar. Participaram no estudo 32 crianças com idades entre os 3 e os 5 anos, 15 alocadas ao Grupo de Controlo, que não participou na intervenção e 17 ao Grupo Experimental (GE), que participou durante 10 semanas em sessões bissemanais, envolvendo atividades semi-dirigidas de jogo de exercício, relaxação e simbolização. A autorregulação das crianças foi avaliada através de duas provas, antes e após a intervenção. No final do programa, o GE evidenciou uma melhoria significativa da autorregulação, avaliada por ambas as provas, comparativamente ao grupo de controlo. Os resultados sugerem que o OUT to IN contribui para o desenvolvimento da autorregulação de crianças de idade pré-escolar

Disordered Boson Systems: A Perturbative Study

A hard-core disordered boson system is mapped onto a quantum spin 1/2 XY-model with transverse random fields. It is then generalized to a system of spins with an arbitrary magnitude S and studied through a 1/S expansion. The first order 1/S expansion corresponds to a spin-wave theory. The effect of weak disorder is studied perturbatively within such a first order 1/S scheme. We compute the reduction of the speed of sound and the life time of the Bloch phonons in the regime of weak disorder. Generalizations of the present study to the strong disordered regime are discussed.Comment: 27 pages, revte

17β-Estradiol Treatment Protects Lungs Against Brain Death Effects in Female Rat Donor

Background: Brain death (BD) affects the viability of lungs for transplantation. A correlation exists between high lung inflammation after BD and the decrease in female sex hormones, especially estradiol. Therefore, we investigated the effects of 17β-estradiol (E2) treatment on the lungs of female brain dead rats. Methods: Female Wistar rats were divided into 4 groups: BD (submitted to BD for 6 h), sham (false-operated), E2-T0 (treated with E2 immediately after BD; 50 μg/ml, 2 ml/h), and E2-T3 (treated with E2 after 3 h of BD; 50 μg/ml, 2 ml/h). Lung edema, hemorrhage, and leukocyte infiltration were analyzed. Adhesion molecules were evaluated and analysis of NO synthase gene and protein expression was performed using RT-PCR and immunohistochemistry, respectively. Release of chemokines and matrix degradation in the lungs were analyzed. Results: BD increased leukocyte infiltration, as shown by intravital microscopy (P=0.017), bronchoalveolar lavage cell count (P=0.016), the release of inflammatory mediators (P=0.02), and expression of adhesion molecules. BD also increased microvascular permeability and the expression and activity of MMP-9 in the lungs. E2 treatment reduced leukocyte infiltration, especially in the E2-T3 group, release of inflammatory mediators, adhesion molecules, and MMP activity in the lungs. Conclusions: E2 treatment was successful in controlling the lung inflammatory response in females submitted to BD. Our results suggest that E2 directly decreases the release of chemokines, restraining cell traffic into the lungs. Thus, E2 has a therapeutic potential, and its role in improving donor lung quality should be explored further

High-precision calculations of van der Waals coefficients for heteronuclear alkali-metal dimers

Van der Waals coefficients for the heteronuclear alkali-metal dimers of Li, Na, K, Rb, Cs, and Fr are calculated using relativistic ab initio methods augmented by high-precision experimental data. We argue that the uncertainties in the coefficients are unlikely to exceed about 1%.Comment: 11 pages, 2 figs, graphicx.st

Simultaneous Magneto-Optical Trapping of Two Lithium Isotopes

We confine 4 10^8 fermionic 6Li atoms simultaneously with 9 10^9 bosonic 7Li atoms in a magneto-optical trap based on an all-semiconductor laser system. We optimize the two-isotope sample for sympathetic evaporative cooling. This is an essential step towards the production of a quantum-degenerate gas of fermionic lithium atoms.Comment: 4 pages, 3 figure

Large atom number dual-species magneto-optical trap for fermionic 6Li and 40K atoms

We present the design, implementation and characterization of a dual-species magneto-optical trap (MOT) for fermionic 6Li and 40K atoms with large atom numbers. The MOT simultaneously contains 5.2x10^9 6Li-atoms and 8.0x10^9 40K-atoms, which are continuously loaded by a Zeeman slower for 6Li and a 2D-MOT for 40K. The atom sources induce capture rates of 1.2x10^9 6Li-atoms/s and 1.4x10^9 40K-atoms/s. Trap losses due to light-induced interspecies collisions of ~65% were observed and could be minimized to ~10% by using low magnetic field gradients and low light powers in the repumping light of both atomic species. The described system represents the starting point for the production of a large-atom number quantum degenerate Fermi-Fermi mixture