Dynamics of the Pionium with the Density Matrix Formalism

The evolution of pionium, the $\pi^+ \pi^-$ hydrogen-like atom, while passing through matter is solved within the density matrix formalism in the first Born approximation. We compare the influence on the pionium break-up probability between the standard probabilistic calculations and the more precise picture of the density matrix formalism accounting for interference effects. We focus our general result in the particular conditions of the DIRAC experiment at CERN.Comment: 14 pages, 2 figures, submitted to J. Phys. B: At. Mol. Phy

A Sheep and Catlle Diet Selection Study on a Fertilized Native Sward in Uruguay

This study was undertaken during winter, spring and summer 1997, located in the basaltic region of Uruguay to evaluate the effects of stocking rate (SR) and N and P fertilizer application on sward characteristics and on sheep and cattle diet selection and grazing behaviour. The treatments applied were: a) control (C; without fertilizer application using a SR of 0.9 stock units (SU)/ha), b) T1 (with N and P fertilizer application using a SR of 0.9 SU/ha), c) T2 (with N and P fertilizer application using a SR of 1.2 SU/ha) and d) T3 (with N and P fertilizer application using a SR of 1.5 SU/ha). In general, compared with C, fertilized treatments resulted in increments in sward surface height (SSH) and sheep bite weight (BW): a) winter (3, 8, 5 and 5 cm., P \u3c 0.01; 79, 142, 139 and 92 mg DM/bite, P \u3c 0.05), b) spring (3, 8, 5 and 6 cm., P \u3c 0.01; 108, 188, 115 and 215 mg DM/bite, P \u3c 0.01), and c) summer (7, 14, 11 and 8 cm., P \u3c 0.01;146, 199, 182 and 131 mg DM/bite, P \u3c 0.05) for C, T1, T2 and T3, respectively. In general, the nutritive value of diet selected by sheep and cattle was higher than that of the pasture on offer, and higher in sheep than in cattle: a) winter (17, 18 and 16% crude protein, CP, P \u3c 0.05; 39, 37 and 41% acid detergent fiber, ADF, P \u3c 0.05), b) spring (11, 14 and 11% CP, P \u3c 0.05; 42, 33 and 37% ADF, P \u3c 0.01), and c) summer (8, 10 and 9% CP, P \u3c 0.05; 50, 40 and 45% ADF, P \u3c 0.01) for pasture on offer, sheep and cattle diets, respectively. This study demonstrated the importance of fertilizing native swards to improve production, structure, nutritive value, and animal carrying capacity and animal performance. It also shows the important role that diet selection plays in determining the nutritive value of the forage eaten by sheep and cattle, and stresses the greater selective ability of sheep over cattle

A Comparative Grazing Study of Sheep and Cattle Diet Selection on Native Pastures in Uruguay

An experiment was carried out during winter, spring and summer 1997, on native pastures of the basaltic region of Uruguay to evaluate the effects of different herbage mass levels (high, medium and low) on sward characteristics and on sheep and cattle diet selection and grazing behaviour. Higher herbage masses resulted in increments in herbage accumulation and sheep bite weight: winter (1880, 1513 and 610 kg DM ha-1, P \u3c 0.01; 199, 148 and 128 mg DM/bite, P \u3c 0.01), and summer (3046, 2175 and 1172 kg DM ha-1, P \u3c 0.01; 214, 175 and 143 mg DM/bite, P \u3c 0.01) for high, medium and low herbage mass levels respectively. The nutritive value of diet selected by sheep and cattle was higher than that of the herbage on offer, and higher in sheep than in cattle: winter (10.2, 15.9 and 12.5% crude protein, CP, P \u3c 0.05; 49.2, 32.4 and 38.1% acid detergent fiber, ADF, P \u3c 0.01, and summer (7.4, 10 and 9.5% CP, P \u3c 0.05; 51.1, 36.8 and 43% ADF, P \u3c 0.01) for herbage on offer, sheep and cattle diets respectively. These contrasting results found in the nutritive value were closely associated with differences in the proportions of the botanical components recorded, particularly the differential contribution of dead material. This experiment quantified the importance of diet selection in determining the nutritive value of the forage eaten by sheep and cattle on the native pastures of the basaltic region of Uruguay and established some relationships between diet selection and grazing management, involving animal selectivity ability differences (sheep versus cattle) and seasonal effects

Drought affects the performance of native oak seedlings more strongly than competition with invasive crested wattle seedlings

Two of the most important processes threatening vulnerable plant species are competitive displacement by invasive alien species and water stress due to global warming. Quercus lusitanica, an oak shrub species with remarkable conservation interest, could be threatened by the expansion of the invasive alien tree Paraserianthes lophantha. However, it is unclear how competition would interact with predicted reductions in water availability due to global climate change. We set up a full factorial experiment to examine the direct interspecific competition between P. lophantha and Q. lusitanica seedlings under control and water-limited conditions. • We measured seed biomass, germination, seedling emergence, leaf relative growth rate, biomass, root/shoot ratio, predawn shoot water potential and mortality to assess the individual and combined effects of water stress and interspecific competition on both species. • Our results indicate that, at seedling stage, both species experience competitive effects and responses. However, water stress exhibited a stronger overall effect than competition. Although both species responded strongly to water stress, the invasive P. lophantha exhibited significantly less drought stress than the native Q. lusitanica based on predawn shoot water potential measurements. • The findings of this study suggest that the competition with invasive P. lophantha in the short term must not be dismissed, but that the long-term conservation of the native shrub Q. lusitanica could be compromised by increased drought as a result of global change. Our work sheds light on the combined effects of biological invasions and climate change that can negatively affect vulnerable plant species

Direct calculation of the probability of pionium ionization in the target

We performed the first direct calculation of the probability of pionium (pi+pi- atom) ionization in the target. The dependence of the probability of pionium ionization in the target as a function of the pionium lifetime is established. These calculations are of interest of the DIRAC experiment at CERN, which aims to measure the pionium lifetime with high precision.Comment: 11 pages, 4 figures; submitted to "Physics of Atomic Nuclei" ("Yadernaya Fizika"

ALERT Doctoral School 2012: advanced experimental techniques in geomechanics

The twenty-second session of the European Graduate School 2012 (called usually ALERT Doctoral School) entitled Advanced experimental techniques in geomechanics is organized by Cino Viggiani, Steve Hall and Enrique Romero.Postprint (published version

Lanthanide molecular nanomagnets as probabilistic bits

Over the decades, the spin dynamics of a large set of lanthanide complexes have been explored. Lanthanide-based molecular nanomagnets are bistable spin systems, generally conceptualized as classical bits, but many lanthanide complexes have also been presented as candidate quantum bits (qubits). Here we offer a third alternative and model them as probabilistic bits (p-bits), where their stochastic behavior constitutes a computational resource instead of a limitation. We present a modelling tool for molecular spin p-bits, we demonstrate its capability to simulate bulk magnetic relaxation data and ac experiments and to simulate a minimal p-bit network under realistic conditions. Finally, we go back to a recent systematic data gathering and screen the best lanthanide complexes for p-bit behavior, lay out the performance of the different lanthanide ions and chemical families and offer some chemical design considerations

Characterization and Engineering Properties of Dry and Ponded Class-F Fly Ash

Characterization studies conducted on Class-F fly-ash specimens gathered from different producers in the southeastern United States confirm general trends reported for fly ash worldwide. Additional tests and detailed analyses explain the spread in specific gravity (interparticle porosity cenospheres), highlight the tendency to segregation and layering, and show marked ferromagnetism. Furthermore, data show that early diagenetic cementation—within days after wetting—hinders densification and produces a fabric that is prone to collapse. New procedures are specifically developed to diagnose and characterize early diagenesis, including (1) pH measurements as an indicator of diagenetic potential, (2) test protocols to assess early diagenesis using oedometer tests and shear-wave velocity, and (3) procedures to determine realizable unit weights as reference values for the analyses of contractive or dilative tendencies and instability. In the absence of early diagenetic cementation, dilative fly-ash behavior is expected in the upper ≈20  m under monotonic shear loading. Flow instability may follow the failure of the containment structure if the ponded ash is saturated and has experienced hindered densification

Estimation of the hydraulic parameters of unsaturated samples by electrical resistivity tomography

In situ and laboratory experiments have shown that electrical resistivity tomography (ERT) is an effective tool to image transient phenomena in soils. However, its application in quantifying soil hydraulic parameters has been limited. In this study, experiments of water inflow in unsaturated soil samples were conducted in an oedometer equipped to perform three-dimensional electrical measurements. Reconstructions of the electrical conductivity at different times confirmed the usefulness of ERT for monitoring the evolution of water content. The tomographic reconstructions were subsequently used in conjunction with a finite-element simulation to infer the water retention curve and the unsaturated hydraulic conductivity. The parameters estimated with ERT agree satisfactorily with those determined using established techniques, hence the proposed approach shows good potential for relatively fast characterisations. Similar experiments could be carried out on site to study the hydraulic behaviour of the entire soil deposi

Perampanel outcomes at different stages of treatment in people with focal and generalized epilepsy treated in clinical practice: Evidence from the PERMIT study

IntroductionThe PERMIT study is the largest pooled analysis of perampanel (PER) clinical practice data conducted to date.MethodsThis post-hoc analysis of PERMIT investigated the effectiveness, safety and tolerability of PER when used as early add-on therapy (after failure of one or two previous antiseizure medications) in comparison with late add-on therapy (after failure of three or more previous antiseizure medications). Retention and effectiveness were assessed after 3, 6, and 12 months, and at the last visit (last observation carried forward). Effectiveness was assessed by seizure type (total seizures, focal seizures, generalized tonic-clonic seizures [GTCS]) and assessments included seizure freedom rate and responder rate. Safety and tolerability were assessed by evaluating adverse events (AEs) and discontinuation due to AEs.ResultsThe Full Analysis Set included 1184 and 2861 PWE treated with PER as early and late add-on therapy, respectively. Compared to the late add-on subgroup, the early add-on subgroup was characterized by later mean age at epilepsy onset, shorter mean duration of epilepsy, lower rates of intellectual disability and psychiatric comorbidity, and lower frequency of seizures per month, suggesting a less severe form of epilepsy in this subgroup. After 12 months, retention was significantly higher in the early versus late add-on subgroup (67.7% vs. 62.4%; p = 0.004). At the last visit, responder rates in the early versus late add-on subgroup were significantly higher for total seizures (68.2% vs. 39.3%; p &amp;lt; 0.001), focal seizures (65.0% vs. 36.8%; p &amp;lt; 0.001) and GTCS (83.7% vs. 67.2%; p &amp;lt; 0.001), as were seizure freedom rates (total seizures, 35.9% vs. 11.9% [p &amp;lt; 0.001]; focal seizures, 29.4% vs. 8.7% [p &amp;lt; 0.001]; GTCS, 69.0% vs. 48.1% [p &amp;lt; 0.001]). Incidence of AEs was significantly lower in the early versus late add-on subgroup (42.1% vs. 54.7%; p &amp;lt; 0.001), as was the rate of discontinuation due to AEs over 12 months (15.0% vs. 18.1%; p = 0.031).DiscussionThis study demonstrated that PER was effective and generally well tolerated when initiated as early or late add-on therapy, but it was significantly more effective and better tolerated when initiated early. These findings support PER's use as a broad-spectrum, early add-on therapy for use in PWE with focal and generalized seizures.</jats:sec