The price of victory: the Sunflower Ordnance Works and Desoto and Eudora Kansas

Call number: LD2668 .R4 HIST 1989 V36Master of ArtsHistor

The rise of pertussis in Malta in 2011 : a case for adolescent and adult pertussis booster vaccination

Notwithstanding the high rates of pertussis infant vaccination coverage in developed countries, Bortedella pertussis infections are manifesting a changing epidemiological pattern of disease. Of notable concern is the rise of pertussis in adolescents and adults. This changing picture is largely attributable to waning immunity after natural infection or vaccination. The belief that pertussis is chiefly a childhood disease is a common misconception. A significant rise of pertussis cases in Malta in older age groups was recorded in 2011. The addition of an adolescent and/or an adult booster dose against pertussis should be strongly considered.peer-reviewe

Attenuation of Kappa-opioid receptor sensitivity changes after chronic ethanol exposure in response to voluntary exercise

Exercise has been known to help alleviate addiction for many years. This research investigates the role of exercise on the mesolimbic dopamine circuit, specifically the attenuation of Kappa-opioid receptor sensitivity and how this plays a role in ethanol addiction

Number of Active Social Media Users as Predictors of HIPAA Infringements

HIPAA Infringements Correlate Linearly with Number of Social Media Users. Social media use has made information sharing much easier – including protected health information. Interestingly, as social media has become more popular over the years, HIPAA violations have also become more common. The calculated R and P values suggest a strong correlation exists between social media use and HIPAA complaints

LSTM-based Recurrent Neural Network Predicts Influenza-like-illness in Variable Climate Zones

Purpose: Influenza virus is responsible for a recurrent, yearly epidemic in most temperate regions of the world. For the 2021-2022 season the CDC reports 5000 deaths and 100,000 hospitalizations, a significant number despite the confounding presence of SARS-CoV-2. The mechanisms behind seasonal variance in flu burden are not well understood. Based on a previously validated model, this study seeks to expand understanding of the impact of variable climate regions on seasonal flu trends. To that end, three climate regions have been selected. Each region represents a different ecological region and provides different weather patterns showing how the climate variables impact flu transmission in different regions. Methods: An LSTM-Based recurrent neural network was used to predict influenza-like-illness trends for three separate locations: Hawaii, Vermont, and Nevada. Flu data were gathered from the CDC as weekly influenza-like-illness (ILI) percents. Weather data were collected from Visual Crossing and included temperature, UV index, solar radiation, precipitation, and humidity. These weather data sets were chosen based on previous work results and a literature search. Data were prepared and the model trained as described previously. Results: All three regions showed strong seasonality of flu trends with Hawaii having the largest absolute ILI values. Temperature showed a moderate negative correlation with ILI in all three regions (Vermont = -54, Nevada = -0.56, Hawaii = -0.44). Humidity was moderately correlated in Nevada (0.47) and weakly correlated with ILI in Hawaii (0.22). Vermont ILI did not correlate with humidity. Precipitation and wind speed were weakly correlated in all three regions. Solar radiation and UV index showed moderate correlation in Vermont (-0.33, -0.36) and Nevada (-0.5263, -0.55) however only weak correlation in Hawaii (-0.15, -0.18). When trained on the complete data set model performance at +1 week was comparable to the previously validated model. Conclusions: Preliminary results indicate that temperature is a moderate predictor of ILI rates. Additionally, humidity, solar radiation, and UV index present promising prediction variables. Initial modeling attempts revealed acceptable performance in all regions. While seasonality appeared similar in each region, differences in correlation with weather variables may reveal variability in the driving forces behind ILI rates

The human Schwann cell transcriptome: species-specificity, long-term stability and changes with differentiation

Cultured Schwann cells of human origin differ from those isolated from experimental animals in both phenotype and function. However, the basis for this divergence and its significance to potential clinical applications of the primary cells are not fully understood. In this study, we used RNA-seq to comprehensively analyze the human Schwann cell transcriptome and compare it to that of ratcells. We also studied the transcriptomics profiles of human Schwann cells subjected to: (1) the pro-mitogenic effect of growth factors in cells undergoing serial passaging in vitro, and (2) the pro-differentiating action of cAMP, a signal known to promote myelin gene expression in rodent cells.Despite the human Schwann cell transcriptome differedas much as 44% from that of rat Schwann cells established under identical conditions, the human cells maintained their expected Schwann cell identity regardless of sub-culture and the continued influence of mitogenic factors. Strikingly, the transcriptomes of low passage (proliferative) and late passage (senescent) human Schwann cells were essentially undistinguishable with the exception of roughly 100 differentially expressed genes in the senescentpopulations. On the contrary, the human Schwann cell transcriptome was readily and persistently shifted in response to a single treatment with cAMP analogs as highlighted by the >1,300 genes that were upregulated and the >1,700 genes that were downregulated within 1-day post-stimulation. In sum, these results confirmed that human Schwann cellsmaintain their typical gene expression profiles in culture unless challenged with a strong pro-differentiating stimulus. The observed stability of the human Schwann celltranscriptome in the face of expansion and mitogenic stimulation adds a level of safety for theuse of these glial cells in clinical transplantation.Fil: Monje, Paula. Indiana University; Estados Unidos. University of Miami; Estados UnidosFil: Sant, David. University of Miami; Estados UnidosFil: Andersen, Natalia Denise. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur. Instituto de Investigaciones Bioquímicas de Bahía Blanca; ArgentinaFil: Camarena, Vladimir. University of Miami; Estados UnidosFil: Wang, Gaofeng. University of Miami; Estados UnidosXIV European Meeting on Glial cells in Health and DiseasePortoPortugalEuropean Meeting on Glial Cells in Health and Diseas

Biotrickling filter modeling for styrene abatement. Part 1: Model development, calibration and validation on an industrial scale

Peer ReviewedPostprint (author's final draft

Electromagnetic Scattering Analysis of Simple Targets Embedded in Planar Multilayer Structures: Remote Sensing Applications

Non

De Novo Microdeletion Spanning YWHAE and CRK in an Individual with Intellectual Disability and Stunted Growth

In this report, we present a case of a 20-year-old female with congenital intellectual disability, stunted growth, and hypothyroidism. Competitive genetic hybridization (CHG) revealed a loss of a portion of 17p13.3 at least 195 Kb in size, not present in either parent. This area of chromosome 17 is associated with Miller-Dieker Syndrome (MDS) and Isolated Lissencephaly Sequence (ILS), but these conditions are related predominantly to PAFAH1B1, which is not included in the patient’s deletion