Spectrophotometric experiment on the Verera-11 and Venera-12 descent vehicles: Some results of the analysis of the spectrum of the daytime sky of Venus

The spectra of the daytime sky of Venus were recorded on the Venera-11 and Venera-12 descent vehicles at various altitudes above the planet's surface, within the interval of 4500 to 12,000 Angstroms. The angular distribution of the brightness of the scattered radiation was recorded and the ratio of water and carbon dioxide were studied, with respect to the cloud cover boundaries

Clinical factors associated with high glycemic variability defined by coefficient of variation in patients with type 2 diabetes

Antecedentes: La Variabilidad Glucémica Alta (VHG) ha convertirse en un predictor más fuerte de hipoglucemia. Sin embargo, aún se desconocen los factores clínicos asociados con el VHG. Objetivo:Determinar las variables clínicas que se asociaron con un coeficiente de variación (CV) superior al 36% evaluado mediante monitorización continua de glucosa (MCG) en un grupo de pacientes con diabetes mellitus. Métodos: Se evaluó una cohorte de pacientes con diabetes tipo 2 (T2D). Se evaluaron variables demográficas, HbA1c, tasa de filtración glomerular (TFG) y régimen de tratamiento. Se realizó un análisis bivariado, para evaluar la asociación entre la variable resultado (CV > 36%) y cada una de las variables independientes. Se construyó un modelo multivariado para evaluar las asociaciones después de controlar las variables de confusión. Resultados:Se analizaron los datos de MCG de 274 pacientes. CV> 36% estuvo presente en 56 pacientes (20,4%). En el análisis bivariado se incluyeron variables demográficas y clínicas, como tiempo desde el diagnóstico, antecedente de hipoglucemia, A1c, FG y tratamiento instaurado. En el análisis multivariante, FG 9% (OR 2,81; IC 1,05,7,51; p:0,04) y antecedentes de hipoglucemia (OR 2,09; IC 1,02, 4,32; p: 0,04) se asociaron con VHG. El tratamiento con iDPP4 (OR 0,39; IC 0,19, 0,82; p: 0,01) y AGLP1 (OR 0,08; IC 0,01, 0,68; p: 0,02) se asoció inversamente con la VG. Conclusión:Variables clínicas como FG 9% y antecedentes de hipoglucemia se asocian a un VG alto. Nuestros datos sugieren que el uso de tecnología y tratamientos capaces de reducir la variabilidad glucémica podría ser útil en esta población para reducir el riesgo de hipoglucemia y mejorar el control glucémico.Q3Background: High glycemic Variability (HGV) has become a stronger predictor of hypoglycemia. However, clinical factors associate with HGV still are unknown. Objective: To determine clinical variables that were associated with a coefficient of variation (CV) above 36% evaluated by continuous glucose monitoring (CGM) in a group of patients with diabetes mellitus. Methods: A cohort of patients with type 2 diabetes (T2D) was evaluated. Demographic variables, HbA1c, glomerular filtration rate (GFR) and treatment regimen were assessed. A bivariate analysis was performed, to evaluate the association between the outcome variable (CV> 36%) and each of the independent variables. A multivariate model was constructed to evaluate associations after controlling for confounding variables. Results: CGM data from 274 patients were analyzed. CV> 36% was present in 56 patients (20.4%). In the bivariate analysis, demographic and clinical variables were included, such as time since diagnosis, hypoglycemia history, A1c, GFR and treatment established. In the multivariate analysis, GFR 9% (OR 2.81; CI 1.05,7.51; p:0.04) and hypoglycemia history (OR 2.09; CI 1.02,4.32; p:0.04) were associated with HGV. Treatment with iDPP4 (OR 0.39; CI 0.19,0.82; p:0.01) and AGLP1 (OR 0.08; CI 0.01,0.68; p:0.02) was inversely associated with GV. Conclusion: Clinical variables such as GFR 9% and a history of hypoglycemia are associated with a high GV. Our data suggest that the use of technology and treatments able to reduce glycemic variability could be useful in this population to reduce the risk of hypoglycemia and to improve glycemic control.Revista Internacional - Indexad

Engaging patients and clinicians through simulation: rebalancing the dynamics of care

This paper proposes simulation-based enactment of care as an innovative and fruitful means of engaging patients and clinicians to create collaborative solutions to healthcare issues. This use of simulation is a radical departure from traditional transmission models of education and training. Instead, we frame simulation as co-development, through which professionals, patients and publics share their equally (though differently) expert perspectives. The paper argues that a process of participatory design can bring about new insights and that simulation offers understandings that cannot easily be expressed in words. Drawing on more than a decade of our group’s research on simulation and engagement, the paper summarises findings from studies relating to clinician-patient collaboration and proposes a novel approach to address the current need. The paper outlines a mechanism whereby pathways of care are jointly created, shaped, tested and refined by professionals, patients, carers and others who are affected and concerned by clinical care

The Potential of Electromobility in Austria: An Analysis Based on Hybrid Choice Models

This paper analyses the impact of the introduction of electromobility in Austria, focusing specifically on the potential demand for electric vehicles in the automotive market. We estimate discrete choice behavioral mixture models considering latent variables; these allows us to deal with this potential demand as well as to analyze the effect of different attributes of the alternatives over the potential market penetration. We find out that some usual assumptions regarding electromobilityalso hold for the Austrian market (e.g. proclivity of green-minded people and reluctance of older individuals), while others are only partially valid (e.g. the power of the engine is not relevant for purely electric vehicles). Along the same line, it was possible to establish that some policy incentives would have a positive effect over the demand for electrical cars, while others - such as an annual Park and Ride subscription or a one-year-ticket for public transportation - would not increase thewillingness-to-pay for electromobility. Our work suggests the existence of reliability thresholds, concerning the availability of charging stations. Finally this paper enunciates and successfully tests an alternative approach to address unreported information regarding income in presence of endogeneity and multiple information sources

The age of the oldest Scandinavian glaciations in mid-eastern Poland and southwestern Belarus

Analysis of type localities of Pleistocene deposits from mid-eastern Poland (Kozi Grzbiet, Łuków, Biała Podlaska and Wilczyn) and southwestern Belarus (Smolarka and Postolovo) has provided a new view on the age, limits and correlation of the oldest Scandinavian glaciations in the area. Integration of palaeontological data with determination of the Brunhes/Matuyama boundary (780 ka) at Kozi Grzbiet and Smolarka suggests that the first glaciation (Narevian) preceded this boundary and had a slightly smaller extent in SW Belarus than hitherto considered. The second glaciation (Nidanian) occurred slightly above or at this palaeomagnetic boundary. In Poland it is the first South Polish Glaciation, a till of which can be traced as far as the Holy Cross Mts. In SW Belarus it is represented by a till to the south of Brest and Bereza, and connected there with the oldest glaciation

Paleogeographical interpretation of paleochannel fill in the Biebrza river valley at Lipowo site (NE Poland)

Четвертичная геологияPart of the research was carried out in cooperation with the project «Preservation of wetland habitats in the upper Biebrza Valley» LIFE11/NAT/PL/422

Paleogeographical interpretation of paleochannel fill in the Biebrza river valley at Lipowo site (NE Poland)

Четвертичная геологияPart of the research was carried out in cooperation with the project «Preservation of wetland habitats in the upper Biebrza Valley» LIFE11/NAT/PL/422

Supra-regional correlations of the most ancient paleosols and Paleolithic layers of Kostenki-Borschevo region (Russian Plain)

International audienceThe archaeological site Kostenki12, located on the Middle Don River, provides a key stratigraphic profile for regional paleopedological, paleoenvironmental, geological and cultural sequences, containing the oldest known cultural layers of the region (layer V - Paleolithic, layer IV - Upper Paleolithic, layer III - Kostenki-Strelets culture early phase) dating to the early part of MIS3, or, in chronometric terms, to 54-42 ka. Kostenki12 complements Kostenki14 (Markina Gora), which is a key profile for the interval 42-27 ka. The new data from Kostenki12 show that the East European Upper Paleolithic began similar to 45 ka. The stratigraphy exhibits similarities to that of Borschevo5. The Kostenki12 pollen diagramis correlated with: 1) other pollen diagrams from Kostenki-Borschevo region; 2) the most detailed climatostratigraphical scale of the Russian Plain Late Pleistocene; 3) O-16/O-18 Greenland GISP2 scale; 4) C-13/C-14 record from stalagmite at Villars Cave (France), as well as with pollen records (5-7) from: 5) Lake Monticchio (Italy), 6) southern Black Sea (M72/5-25-GC1) and 7) Glinde and Moershoofd (northern Germany). The results of the supra-regional paleoenvironmental correlations demonstrate that the lowest Paleolithic layer V and paleosol D, characterized by elm dominance, correlate to the second half of the optimum of the Glinde interstadial at 51-48 ka, corresponding to DO 14. The earliest Upper Paleolithic layer IV and paleosol B, characterized by coexistence of elm forests and wet meadows, began to form during the second part of the Moershoofd interstadial optimum at 46-44 ka, correlating with DO 12. Paleosol A and layer III (Kostenki-Strelets culture) began to form after the abrupt end of the Moershoofd interstadial similar to 43.5 ka, during unstable conditions, according to pollen and paleozoological data (steppe with horse dominance and later spruce forest tundra with reindeer dominance in paleozoological complex). These correlations provide more accurate dating of the Paleolithic layers and paleosols at Kostenki-Borschevo, suggesting that previously reported radiocarbon dates on units below CI tephra layer are too young, but that the OSL chronology is generally accurate. (C) 2014 Elsevier Ltd and INQUA. All rights reserved