GENDER-BASED POPULATION IN DURG DISTRICT: A GEOGRAPHICAL DISTRIBUTION

Gender base working population this mines of Male person and Female person working population. In this study area district of Durg are divided the Agriculture and Industrial base working population. This district are population base second position in Chhattisgarh. Population are as per 2011 census report of Durg district 2,68,806 population. In this paper is an attempt of population growth are highly increasable but population growth base not increase the worker in Durg district. The statistical survey report 2011 census data base Durg district study place worker are divided the Primary sector worker (66%) and Secondary sector (23%) worker rapidly growth.Further during the study period it has been found that despite performing well on the front of poverty and unemployment reduction, still there is a high concentration of rural and slum area poor and unemployed in this district. So the entailed on the part of government new policy develop the problem of population growth, and unemployment. 2001 census report in population growth rate 17.87 % and 2011 census report is 18.98% in Durg district and working population is 43% of Chhattisgarh

Effect of citric acid and polymer blend on characteristics of ofloxacin floating matrix tablets by factorial design

The present investigation deals with the development of floating matrix tablet containing Ofloxacin, to prolong the gastric residence time, thereby effective in eradication of Helicobacter pylori from the gastric mucosa. A 32 factorial design was employed to formulate floating matrix tablet selecting polymer blend ratio [hydroxypropyl methylcellulose (HPMC) / sodium carboxymethylcellulose (SCMC)] and content of citric acid as independent variables. Time required for 50 % of drug release (t50 %), percentage drug release at 8 h (Q8), floating duration (h) and diffusion exponent (n) were selected as dependent variables. Multiple regression analysis with two way ANOVA revealed statistically significant effect of the two independent variables on the responses studied (P 8 varied from ~ 76 % to ~100 % whereas t50 % ranged from 1.7 h to 3.7 h. The kinetics of drug release fitted best to Higuchi diffusion controlled model.Colegio de Farmacéuticos de la Provincia de Buenos Aire

A longitudinal study on health expenditure in a rural community attached to mahatma Gandhi Institute of Medical Sciences, Sewagram, Maharashtra

Community based study on health expenditure is a rarity in India. A Rural Community based longitudinal study was undertaken in Jaulgaon village of Maharashtra, with objectives of finding out the health expenditure contributed by direct treatment, related travel and relevant loss of wages with certain pertinent associated factors. 50% of the village population was studied (N = 256) by pre-designed, pre-tested schedule following WHO guidelines. A monthly house to house interview was conducted over 12 months. During study period, 78% study subjects suffered some illness with mean illness episode 1.74/person and 6.37/family without any sex difference. The annual health expenditure of the community was Rs 1,576/family, 4,31/person and 2,42/episode, which was about 4.3% of their income. The major part of the expenditure (82%) was for direct treatment cost, followed by loss of wages (12%) and travel related cost (6%). Expenditure was seen to be significantly associated with family income (P = 0.000) and education (P = 0.006)

Formulation and In Vitro Evaluation of Sunflower Oil Entrapped within Buoyant Beads of Furosemide

The purpose of the present study was to develop buoyant beads for the intragastric delivery of furosemide in order to evaluate the effect of incorporated sunflower oil on physiochemical properties of alginate beads. Sunflower oil entrapped buoyant alginate beads of furosemide were prepared by the emulsion-gelation technique. During the preparation of various batches of beads, the ratio of sunflower oil to water (v/v), the ratio of drug to polymer (w/w), were kept as variables at two levels; either high or low. Smooth, spherical beads with nominal weight variation were obtained. All batches of beads floated for 24 hours with a lag time of 5–10 min. The release of drug followed for 5 hours. Higuchi and first order kinetic modeling indicated a diffusion-controlled release of drug from the beads. The study also demonstrated the influence of sunflower oil on drug entrapment (81–95%) and in vitro release. A higher level of oil increased drug entrapment efficiency but retarded drug release rate as compared to a lower level of oil containing beads

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Not AvailableFeed is the costliest input that accounts 50-60% of operational expenditure in aquaculture. To reduce the feed quantity and minimize related environmental impacts arising from feed wastage in aquaculture, natural fish food item, periphyton can be utilized as an alternate option. Milkfish (Chanos chanos), being a herbivore fish, can be cultured by developing periphyton biomass as natural diet and thereby to reduce use of commercial feed. Monoculture of milkfish (15000 no./ha) for 180 days was undertaken in 50 m2 pond enclosures with four different feeding systems: (P0) control with total feeding and no periphyton; P75, P100 and P125 were with periphyton grown on 75, 100 and 125% pond surface area, respectively along with partial feeding. White nylon net (40 mesh) as substrate for periphyton growth was fixed vertically in the epilimnion of pond water. Fish growth (242.29±5.22 g), productivity (3146±60 kg/ha) and benefit-cost ratio (1.81) were significantly highest (P<0.05) with lowest FCR of 1.17±0.02 in P125. FCR could be reduced maximum by 46% compared to P0 in P125 based on the dry matter of periphyton grown in negative control enclosures containing no fish. Therefore, this method is appropriate for monoculture of milkfish to reduce feed cost and ensure environmental sustainabilityNot Availabl

Anticancer Potential of 3-(Arylideneamino)-2- Phenylquinazoline-4(3H)-One Derivatives

Different quinazoline derivatives have showed wide spectrum of pharmacological activities. Some 3- (arylideneamino)-phenylquinazoline-4(3H)-ones have been reported to possess antimicrobial activity. The present study has been undertaken to evaluate the anticancer effect of these quinazolinone derivatives. The quinazolinone derivatives were synthesized as reported earlier. Compounds containing NO2, OH, OCH3, or OH and OCH3 as substituent(s) on the arylideneamino group were named as P(3a), P(3b), P(3c), and P(3d) respectively. Out of these, P(3a) and P(3d) showed better cytotoxic activity than P(3b) and P(3c) on a panel of six cancer cell lines of different origin, namely, B16F10, MiaPaCa-2, HCT116, HeLa, MCF7, and HepG2, though the effect was higher in B16F10, HCT116, and MCF7 cells. P(3a) and P(3d) induced death of B16F10 and HCT116 cells was associated with characteristic apoptotic changes like cell shrinkage, nuclear condensation, DNA fragmentation, and annexin V binding. Also, cell cycle arrest at G1 phase, alteration of caspase-3, caspase- 9, Bcl-2 and PARP levels, loss of mitochondrial membrane potential, and enhanced level of cytosolic cytochrome c were observed in treated B16F10 cells. Treatment with multiple doses of P(3a) significantly increased the survival rate of B16F10 tumor bearing BALB/c mice by suppressing the volume of tumor while decreasing microvascular density and mitotic index of the tumor cells