Impact of resource conservation technologies on soil health and productivity of wheat in rice-wheat cropping system

A field experiment was conducted to investigate the impact of resource conservation technologies on soil health and productivity of wheat in rice-wheat cropping system in split plot design with three replications. The physico-chemical parameters of the soils like pH and EC both maximum decreased almost significantly over control under treatments T2 (Ploughing twice by Cultivator, allowed to decompose weeds for a week then puddling by cross ploughing and planking), T3(Summer ploughing onset of monsoon by mould bold plough to invert the soil once in three years followed by subsequent ploughing by cultivator to puddle the soil) and C5 (GM + Paddy straw @ 50 q/ha) and C6 (GM + Rice husk @ 50 q/ha). Soil data revealed a highly significant increase in organic carbon content along with available N, P2O5 and K2O content under treatments T3 and C6 and their interactions(T3×C6)over control. This might be attributed to the improvement in physico-chemical properties of the soils. The significant (P<0.05) increase in yield attributes and yields of wheat grain and straw over control was observed under influence of the treatments T3 and C6 and their interaction except height and length of ear head. These observations were confirmed by the positive and highly significant correlation of yield of wheat grain with available N (r=0.74**), available P2O5 (r = 0.64**), and available K2O (r = 0.52**). Deep ploughing and green manuring in addition with other organic residues (GM+ rice husk) individually and/ or in combination improved the soil health significantly

GLYCATED HEMOGLOBIN LEVELS IN METABOLIC SYNDROME PATIENTS

Objectives: Metabolic syndrome (MetS) is a cluster of several metabolic disorders including hyperglycemia, reduced high-density lipoprotein cholesterol, and raised triglyceride level in serum, hypertension, and abdominal obesity. Glycated hemoglobin (HbA1c) is used as one of the diagnostic criteria for diabetes and diagnostic tool for MetS. Methods: The present study was conducted at Prasad Institute of Medical Sciences. The study includes 150 patients with MetS as a case and 150 healthy volunteers as a control. MetS was diagnosed according to National Cholesterol Education Program’s Adult Treatment Panel III criteria. HbA1c was assayed in various components of MetS. Results: It was found that HbA1c was significantly higher in MetS patients when compared to control group. Conclusion: Our study suggests that HbA1c might be used as a diagnostic criterion for MetS. Therefore, proper glycemic control should be maintained by maintaining HbA1c level <6.5% to prevent from diabetes and MetS

Assessment of Acute biliary pancreatitis: a prospective observational hospital-based study

Background: Pancreatitis is quite common problem, it may present either as abdominal emergency with fulminant course or as an indolent process leading to long-term medical as well as surgical complications often leading to poor prognosis if not intervened timely. Methods:This was a prospective hospital based observational study conducted at  Department of General Surgery, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India.from November 2015 to July 2016. All cases of ABP admitted over a period of one year were included in the study. The clinical presentation, severity and course of the disease, imaging studies, duration of ICU and hospital stay and timing of ERCP and cholecystectomy were studied. Results: A total of 100 cases were included in the study. Average age was 53.45 years. Pain abdomen was the most common symptom at presentation. About 88% patients had mild to moderate disease while the rest had severe disease. The mean duration of intensive care unit stay was 8-10 days. ERCP was done in 12 cases. Cholecystectomy during the same admission was done in 34 cases. Conclusion: Early intervention definitely reduces morbidity, mortality and recurrent admissions in cases of acute biliary pancreatitis. Same admission laparoscopic cholecystectomy is preferable in mild ABP. All cases of severe ABP must undergo early ERCP irrespective of biliary obstruction. Keywords: pneumonia, hyponatremia, sodium level, children

Study of spectrum and clinical profile of benign breast disease in the rural area: an observational study

Background: Recent understanding of pathophysiology and health awareness may have impact on spectrum of benign breast disease (BBD) in rural area. We have analyzed clinical data of 200 cases of BBD for spectrum and clinical profile to compare with present studies.Materials and Methods: This was a clinical study conducted at Department of General Surgery at Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India. which is located in rural area. This study was done during  from April 2015 to March 2016. Patients presented with different breast related problems like lump in breast, nipple discharge, associated fever and mastalgia were admitted in surgical ward for evaluation.Results: A total of 200 females were included in the study. Fibroadenoma 79(39.5%) and fibroadenosis 49(24.5%) were the commonest diseases, both presenting mostly at 20-30years of age. Left side involvement was most common. The commonest presentation was breast lump which comprised (82%) cases, patients with breast lump 82%, patients with breast pain 36.5% and patients with nipple discharge 3.5%. Conclusion: Benign breast diseases are common problems of 2nd and 3rd decade in females and raises considerable fear of malignancy. The patients of BBDs generally present with one or more of these complaints – breast lump, breast pain or nipple discharge. All the patients with discrete breast lumps should undergo a triple assessment to make an early diagnosis. Key words: Benign breast diseases, Fibroadenoma, Fibrocystic disease, Mastitis

Negative pressure wound therapy in management of abdominal wound dehiscence: a case-control study

Background: Since the 1990’s, negative pressure wound therapy (NPWT) has been used to treat soft tissue defects, burn wounds, and to achieve skin graft fixation. In the field of abdominal surgery, the application of NPWT is increasing in cases with an open abdominal wound requiring temporary wound closure and a second look operation. In the present study, analyzed negative pressure wound therapy in management of abdominal wound dehiscence.Materials and Methods: The study was conducted in the Department of General Surgery Indira Gandhi Institute of Medical Sciences, Patna,Bihar India. This study was done during from Jan 2016 to December 2016.  Institutional ethical approval was obtained before conducting this study.A total of n=100 cases were included in this study.Out of n=100,50were taken as cases in whom intervention was done by applying VAC Therapy and 50 were taken as control in whom only NS dressing was done.Results:In this study major number of patients belonged to the age group between 40-60 years, Abdominal wound dehiscence were more common in males 71 cases (71%) than females 29 cases (29%). Male to female ratio was 2.4:1. The type abdominal wound dehiscence was most commonly partial thickness wound dehiscence 64 case (64%) and full thickness wound dehiscence were 36 (36%).  There was mean wound contraction of 0.82 cm in post VAC patients compared to0.13 cm in post ns dressing. there was significant decrease in wound sepsis of patient by application of negative pressure wound therapy and  patients with negative pressure wound therapy dressing has more number of healing by secondary intention and nil mortalityrate.Conclusion: NPWT significantly reduces the hospital stay of patients, it causes faster and higher degree of wound contraction, reduces wound sepsis thereby reducing morbidity of patient. Keywords: Abdominal wound dehiscence, Negative pressure wound therapy, Vaccum assisted closure

Synthesis of Reconfigurable Multiple Shaped Beams of a Concentric Circular Ring Array Antenna Using Evolutionary Algorithms, Journal of Telecommunications and Information Technology, 2023, nr 1

The approach described in this paper uses evolutionary algorithms to create multiple-beam patterns for a concentric circular ring array (CCRA) of isotropic antennas using a common set of array excitation amplitudes. The flat top, cosec2, and pencil beam patterns are examples of multiple-beam patterns. All of these designs have an upward angle of θ = 0◦. All the patterns are further created in three azimuth planes (φ = 0◦, 5◦, and 10◦). To create the necessary patterns, non-uniform excitations are used in combination with evenly spaced isotropic components. For the flat top and cosecant-squared patterns, the best combination of common components, amplitude and various phases is applied, whereas the pencil beam pattern is produced using the common amplitude only. Differential evolutionary algorithm (DE), genetic algorithm (GA), and firefly algorithm (FA) are used to generate the best 4-bit discrete magnitudes and 5-bit discrete phases. These discrete excitations aid in lowering the feed network design complexity and the dynamic range ratio (DRR). A variety of randomly selected azimuth planes are used to verify the excitations as well. With small modifications in the desired parameters, the patterns are formed using the same excitation. The results proved both the efficacy of the suggested strategy and the dominance of DE over GA as well as FA

Bcl-2 prevents CD95 (Fas/APO-1)-induced degradation of lamin B and poly (ADP-ribose) polymerase and restores the NF-κB signaling pathway

In the study presented here, we investigated the possible interactions between CD95 (Fas/APO-1) and Bcl-2 by studying the effects of Bcl-2 on the modulation of cellular pathways activated by CD95 using HeLa cells as a model system. We report that stable expression of Bcl-2 in HeLa cells is associated with multiple phenotypic changes. Treatment of HeLa cells with anti-CD95 monoclonal antibody (mAb) resulted in preferential degradation of lamin B compared with lamins A and C. Significant lamin B degradation was detected as early as 1 h after anti-CD95 mAb treatment. In contrast, lamins A and C as well as actin remained unchanged until 4 h after treatment with anti-CD95 mAb, a time point that correlated with the period of DNA fragmentation. These results indicate that selective degradation of lamin B is an early cellular event in response to activation of the CD95 pathway and that it precedes DNA fragmentation. Overexpression of Bcl-2 resulted in prevention of lamin B degradation and DNA fragmentation into oligonucleosome fragments in response to the apoptotic signal by anti-CD95 mAb. In addition, in Bcl-2-overexpressing cells that were protected against apoptosis, anti-CD95 mAb-induced cleavage of poly(ADP-ribose) polymerase was completely blocked. Overexpression of Bcl-2 also resulted in restoration of the CD95-mediated signaling pathway involving activation of the transcription factor NF-κB (p50/RelA). These findings suggest that Bcl-2 prevents apoptosis in part by preventing the degradation of major nuclear polypeptides such as lamin B and poly(ADP-ribose) polymerase. In addition, our results demonstrate that CD95-mediated signaling involves activation of NF-κB (p50/RelA)

Cosmogenic Nuclide Tracking of Sediment Recycling From a Frontal Siwalik Range in the Northwestern Himalaya

The Himalayan orogen exports millions of tons of sediment annually to the Indo-Gangetic foreland basin, derived from both hinterland and foreland fold-thrust belts (FTB). Although erosion rates in the hinterland are well-constrained, erosion rates in the foreland FTB and, by extension, the sediment flux have remained poorly constrained. Here, we quantified erosion rates and sediment flux from the Mohand Range in the northwestern Himalaya by modeling and measuring the cosmogenic radionuclide (CRN) 10Be and 26Al concentrations in modern fluvial sediments. Our model uses local geological and geophysical constraints and accounts for CRN inheritance and sediment recycling, which enables us to determine the relative contributions of the hinterland and foreland FTB sources to the CRN budget of the proximal foreland deposits. Our model predictions closely match measured concentrations for a crustal shortening rate across the Mohand Range of 8.0 +/- 0.5 mm yr-1 (i.e., approximately 50% of the total shortening across the Himalaya at this longitude) since 0.75-0.06+0.02 $0.7{5}_{-0.06}{+0.02}$ Ma. This shortening implies a spatial gradient in erosion rates ranging from 0.42 +/- 0.03 to 4.92 +/- 0.34 mm yr-1, controlled by the geometry of the underlying structure. This erosion pattern corresponds to an annual sediment recycling of similar to 2.0 megatons from the Mohand Range to the downstream Yamuna foreland. Converted to sediment fluxes per unit width along the Himalaya, the foreland FTB accounts for similar to 21% +/- 5% of the total flux entering the foreland. Because these sediments have lower 10Be concentrations than hinterland-derived sediment, they would lead to similar to 14% overestimation of 10Be-derived erosion rates, based on Yamuna sediments in the proximal foreland

Excision of choledochal cyst in children by Roux-en-Y hepaticojejunostomy

The aim of this study was to review our experience of total excision with Roux-en-Y hepatico-jejunostomy for the surgical management of type I and type IVa choledochal cysts in 30 children. Among them, 22 were in type I and 8 in type IVa choledochal cysts. All had complete excision and Roux-en-Y hepaticojejunostomy with no morality. Morbidity consisted of prolong drainage (n=2) and late onset cholangitis/pancreatitis (n=4). Choledochal cyst generally has an excellent prognosis with early complete excision and Roux-en-Y hepaticojejunostomy

Parametric optimalization of submerged fermantation conditions for xylanase production Bacillus cereus BSA1 through Taguchi Methodology

Extracellular xylanase production of Bacillus cereus BSA1 was optimized under submerged fermentation using Taguchi orthogonal array (OA). An L18 layout of OA was constructed at three-levels of six factors, i.e. temperature, pH, and xylan, Na2HPO4, NH4NO3 and NaCl concentrations, influencing the xylanase synthesis. The enzyme production was studied in 18 parallel batch systems using different levels of each factor. The results were processed with Qualitek-4 software using ‘bigger is better’ quality character, and combination of 35 oC; pH 6.0; and xylan 0.5; NH4NO3 0.5, Na2HPO4, 0.1; NaCl 0.05 concentrations (in w/v %) with a predictive xylanase production of 7.404 U/ml was obtained. Fermentation experiment was performed for further validating the statistical output, and it resulted 10.24% in the xylanase yield (from 6.44 U/ml to 7.10 U/ml) as compared to one variable at a time (OVAT) design. Interaction effects of the factors individually and in combination can be evaluated by using Taguchi method design of experiment