GOREWEB framework for goal oriented requirements engineering of web applications

In this paper, we propose a framework for modeling goal driven requirements of web applications. Web engineers mostly focus on design aspects only overlooking the real goals and expectations of the user. Goal oriented Requirement Engineering is a popular approach for Information system development but has not been explored much for Web applications. However, in today's times Web is dominating in every business making it imperative that its requirements are analyzed carefully and in profundity. Goal driven requirements analysis helps in capturing stakeholders' goals very finely, by choosing between alternatives and resolving conflicts. Detailed classification of both functional and non-functional requirements specific to web applications is discussed in the presented work. A framework, GOREWEB (Goal oriented Requirements Engineering for Web Applications) is proposed for analyzing goals and translating them into functional and non-functional web requirements

A Comparative Clinical Study of Shamana Therapy and Shodhana Purvaka Shamana Therapy in the Management of Tamaka Shwasa w.s.r to Bronchial Asthma

Ayurveda is the science of life which deals with the prevention and cure of diseases. From the first breath of newly born till the last breath i.e, Shwasochhwasa Kriya is the sign of life. Any disturbance in this process leads to Shwasa Roga. Tamaka Shwasa is one of the important diseases of such disturbance. Shwasa is a Kapha-Vataja disease which is originated from Pittasthana. Tamaka Shwasa is very much similar to bronchial asthma in modern medicine which is a chronic disease of multifactorial origin. Ayurveda describes two type of management of all disease i.e. Shodhana and Shamana Chikitsa. In present scenario Panchakarma therapy is the best way to effectively and safely manage the condition without any specific side effects. It is one of the most effective and complete therapy in the management of the chronic disease such as Tamaka Shwasa (Bronchial Asthma). In Ayurvedic classics both Vamana and Virechana have been described specifically in the management of Tamaka Shwasa. Considering the Ayurvedic concept of treatment of Tamaka Shwasa, in present study we have used Virechana therapy along with certain herbal preparation. In this study we concluded that the cases who were treated with herbal preparation along with Virechana got better relief than herbal preparation alone

Retention of Cognitive Skills in Advanced Cardiac Life Support Training

AbstractRespiratory therapists (RTs) and registered nurses (RNs) who work at a local hospital in the state of Maryland have expressed difficulty retaining the knowledge required to renew their advanced cardiac life support (ACLS) certification. The retention of skills is very important in responding to a life-threatening event, such as cardiac arrest. The ACLS is a key clinical competency for these clinicians, suggesting a need to understand how their retention and learning can be improved. Accordingly, the purpose of this qualitative study was to better understand the factors that may affect RNs and RTs in learning and retaining the knowledge and skills needed to renew the ACLS recertification. The conceptual framework was based on Kolb’s experiential learning and Gurbin’s information-processing theory. The research questions focused on the difficulties that RTs and RNs described in retaining the knowledge and skills from the ACLS recertification course and the strategies that RTs and RNs perceive in helping them to retain the knowledge and skills. The study was carried out through in-person, qualitative semistructured interviews with 5 RTs and 5 RNs. Interview data were analyzed through qualitative thematic analysis. As a result, there were themes developed and the outcome was that regular training and recertification in the knowledge and skills required to provide safe, effective care is essential. The study promotes social change by giving an opportunity to healthcare providers to practice and translate evidence-based practice into clinical practice. The results revealed that in order to successfully retain cognitive skills, educational programs need to be improved to enhance patient outcomes from better ACLS retention

An exploratory study using the OMI scale to assess the opinion toward mental illness among young adults

Background: Public perception of mental illness is critical for successful treatment seeking behaviour as well as for early diagnosis and surveillance of disease. Two hundred eleven young patients were interviewed at Department of psychiatry, Sir Sunderlal Hospital, Varanasi with the help of consecutive sampling method. Objective: To assess the opinion towards mental illness among young adults by using the opinion on mental illness scale (OMI). Methods: Data was collected using the opinion about mental illness scale (OMI) which consists of 51 questions out of which, 15 questions directly related to the cause, care, and management of mental illness were randomly selected and analyzed. Analysis was done showing Percentage and chi-square tests to see the significance of scores between the respondents. Results: The finding shows that more than 70% of respondents believe that mental illness is a consequence of bad behavior, lack of willpower, or negative beliefs and gap in the treatment seeking behavior and understanding the cause of disease was found. Conclusions: Opinions on Mental health have received increasing attention as a useful strategy to promote early identification of mental illness, reduce stigma and enhance help-seeking behaviors. As part of the National Mental Health Programme, there is a need to raise awareness in order to enhance understanding of mental illness in facilitating early diagnosis and treatment of disease

Hepatorenal protective action of Spirulina platensis against beryllium induced hepatorenal dysfunction and histopathological alterations in rats

23-32Beryllium (Be) is highly toxic to human, induces oxidative stress and leads to Chronic Beryllium Disease (CBD) or berylliosis, apoptosis and cancer. In this study, we have investigated the antioxidative and hepatorenal protective potential of Spirulina platensis (SP) against beryllium (Be) induced alterations in hepatorenal biochemical parameters, oxidative stress and histopathological alterations in rats. Different doses of SP (50, 100, 200 and 400 mg/kg, p.o.) were administered (once a day daily for 7 days) against Be(NO3)2 (1 mg/kg, i.p. once a day daily, for 28 days) induced toxic menifestations in female Wistar rats. Be decreased GSH, SOD, CAT, G-6-Pase, ALP and ATPase activities and increased TBARS and ACP activity in liver and kidney. Be enhanced ALT, AST, bilirubin, uric acid, creatinine, total cholesterol and decreased haemoglobin, total protein, sugar in blood. Be deposited in vital organs of rats and altered the histoarchitecture of liver and kidney. Different doses of SP showed dose dependent recovery. SP @400 mg/kg showed significant recovery against Be induced oxidative stress, maintained hepatorenal function towards normal and reduced beryllium body burden. Results of the study. well supported by histopathological observations, conclude that SP possesses hepatorenal protective potential against Be induced toxicity in rats

Protective potential of Moringa oleifera Lam. along with curcumin and piperine against beryllium-induced alterations in hepatorenal biochemistry and ultramorphology in rats

Moringa oleifera Lam. (Moringaceae) is a medicinally important plant, used as traditional medicine all over the world particularly in South Asia and India. Hydroalcoholic (50% v/v) root extract of M. oleifera (150 mg/kg, p.o.) with piperine (2.5 mg/kg, p.o), or curcumin (5.0 mg/kg, p.o.) was administered daily for 1 week in Female Wistar albino rats against beryllium toxicity (1.0 mg/kg, i.p. daily for 5 weeks). Beryllium altered hepatorenal function and enhanced the leakage of AST, ALT, and LDH, depleted SALP activity, and increased the level of urea, uric acid, creatinine, triglyceride and total cholesterol in the blood. Beryllium altered tissue biochemical parameters by a decrease in SDH, ALPase, ATPase activities, and increased ACPase activity, depleted hemoglobin and ALAD activity with an increase in ALAS activity and serum bilirubin. A significant amount of beryllium deposited in the liver, kidney, spleen, and bones. M. oleifera with curcumin showed better antitoxic potential by reversal of hepatorenal function towards normal and restored the activity of SDH, ALPase, ATPase, ACPase, and hemoglobin level normal. M. oleifera with curcumin effectively mobilized beryllium from the body and restored ultrastructure of liver and kidney. It was concluded that curcumin enhances the antitoxic potential of M. oleifera root extract and reduces beryllium body burden in rats

Gallic acid-cholesterol conjugate: Synthesis spectroscopic characterization and quantum chemical calculations-an experimental and theoretical approach

Gallic acid is the major constituent in fruits Phyllanthusemblica (amla), of the family phyllanthaceae. Gallic acid was first methylated to 3,4,5 trimethoxygallic acid, which upon esterification using steglich method with cholesterol resulted in the product (3S,8S,10R,13R,17R) -10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro - 1H - cyclopenta[a]phenanthren-3-yl 3,4,5-trimethoxybenzoate. The synthesized compound has been characterized by 1H NMR, 13C NMR, UV, FT-IR and mass spectroscopy. Density functional theory (B3YLP) using a 6-31G (d,p) basis set has been used for quantum chemical calculations. The reactive site and reactivity within the molecule are rendered by global and local reactivity descriptors, whereas AIM (Atom in a molecule) approach illustrated weak molecular interactions within the molecule. The energies of HOMO and LUMO and frontier orbital energy gap are calculated by time dependent DFT approach using the IEFPCM model. A small value for the HOMO-LUMO energy gap indicates easier charge transfer within the synthesized compound. The nucleophilic and electrophilic reactivity is determined by MEP (molecular electrostatic potential) studies. The values calculated for polarizability, dipole moment, and first hyperpolarizability are used to depict the NLO (nonlinear optical) property of the synthesized compound

ANALYSIS OF INVENTORY MODEL WITH PRICE DEPENDENT DEMAND INCLUDING CONSTANT DETERIORATION RATE WITH SALVAGE VALUE, HOLDING COST IS TIME-DEPENDENT AND SHORTAGE IS PARTIALLY BACKLOGGED

In this study, we examine a model of inventory for things that are deteriorating along with the price dependent demand. The deterioration rate is constant and Salvage value is related to goods that are deteriorating, and holding cost is time-dependent. The suggested approach allows for some backlog in the shortage. Based on the length of time it will be before the next replenishment, the backlog rate is determined. This framework is solved to reduce the overall cost of given inventory to showing some numerical examples with sensitivity analysis to find the optimal solution for various parameters

Intermittent Food Absence Motivates Reallocation of Locomotion and Feeding in Spotted Munia (Lonchura punctulata)

Background: Daily feeding and locomotion are interrelated behaviours. The time spent in feeding and rate of food intake depends on food availability. In low food condition, the birds would show intense movement (locomotion) for a longer time throughout the day however during abundant food supply they may chose higher activity and food intake in the morning and evening only. In the present study we hypothesized that in Spotted Munia (Lonchura punctulata), intermittent food availability during day would reallocate their interrelated behaviors, the feeding (food intake) and locomotor activity patterns.  Methods: Two groups of birds (N = 6 each) were kept individually in activity cages under 12L:12D. Group 1 (Control; C) had ad libitum food but group 2 (Treatment; T) had food for 6 hours only (2 h presence followed by 2 h absence; 2P:2A) during 12 hour light period. In the first week, group 2 received food with ‘lights on’ (TI; ZT 0–2, 4–6 and 8–10; where ZT 0= zeitgeber time 0, time of lights ON). In the following week, the food was given 2 hours after ‘lights on’ (TII; ZT 2–4, 6–8, 10–12). The food intake and locomotor activity under each condition were observed.  Results: The results showed that locomotor activity was induced during food deprivation and suppressed during food availability. Also the food deprivation led to increased food intake. Conclusion: Our results suggest that intermittent food availability/ deprivation reallocates the locomotor activity and food intake in Spotted Munia