146 research outputs found

    Efficacy and Safety of Human Placental Extract Solution on Fatigue: A Double-Blind, Randomized, Placebo-Controlled Study

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    Introduction. Fatigue is a common symptom, but only a few effective treatments are available. This study was conducted to assess the efficacy and safety of the human placental extract solution, which has been known to have a fatigue recovery effect. Methods. A total of 315 subjects were randomly assigned to three groups: group 1 (with Unicenta solution administration), group 2 (with exclusively human placental extract administration, excluding other ingredients from the Unicenta solution), and the placebo group. Subsequently, solutions were administered for four weeks. Results. The fatigue recovery rate was 71.00% in group 1, 71.72% in group 2, and 44.21% in the placebo group, which show statistically significant differences between the group 1 and the placebo group (P value = 0.0002), and between group 2 and the placebo group (P value = 0.0001). Conclusion. The human placental extract solution was effective in the improvement of fatigue

    Effect of Apneic Oxygenation via Nasal Prong on Gas Exchange and Vital Signs during Fiberoptic Intubation under General Anesthesia

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    A clinical study for the evaluation of the effect of apneic oxygenation by nasal prong during fiberoptic orotracheal intubation on gas exchange and vital signs has been done on the patients who received tympanomastoidectomy (ASA c1assfication 1 and 2, aged from 20 to 40). Among them, 22 patients were selected whose fiberoptic intubation lasted more than 3 but less than 4 minutes, to observe the changes of Pa02, PaC02, HR, and MAP. 11 patients who underwent fiberoptic orotracheal intubation in apneic state without oxygen administration (Group I) showed similar increases in vital signs to the other 11 patients who received apneic oxygenation (Group II). PaC02 increased more in Group I than in Group II, which was not statistically significant. The differences of Pa02 at 1 and 2 minutes between two groups after removal of oxygen mask and beginning of fiberoptic intubation, were not statistically significant but Group II showed a significantly lesser degree of decrease in Pa02 at 3 minutes. We might say that apneic oxygenation during fiberoptic intubation under general anesthesia is useful because it could delay the onset of hypoxia, thereby provide extra time for intubation. Therefore we could attempt intubation up to 3 minutes on the fully relaxed patient, if we give oxygen via nasal prong

    A study of deep learning algorithm usage in predicting building loss ratio due to typhoons: the case of southern part of the Korean Peninsula

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    The goal of this study is to suggest an approach to predict building loss due to typhoons using a deep learning algorithm. Due to the influence of climate change, the frequency and severity of typhoons gradually increase and cause exponential destruction of building. Therefore, related industries and the government are focusing their efforts on research and model development to quantify precisely the damage caused by typhoons. However, advancement in the accuracy of prediction is still needed, and the introduction of new technology, obtained due to the fourth revolution, is necessary. Therefore, this study proposed a framework for developing a model based on a deep neural network (DNN) algorithm for predicting losses to buildings caused by typhoons. The developed DNN model was tested and verified by calculating mean absolute error (MAE), root mean square error (RMSE) and coefficient of determination (R2). In addition, to further verify the robustness of the model, the applicability of the framework proposed in this study was verified through comparative verification with the conventional multi-regression model. The results and framework of this study will contribute to the present understanding by suggesting a deep learning method to predict the loss of buildings due to typhoons. It will also provide management strategies to related workers such as insurance companies and facility managers
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