121 research outputs found

    Examination of the Development, Implementation, and Monitoring of One Instructional Coaching Program in an Urban, Title I, Elementary School

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    Some schools and school districts have implemented instructional coaching programs to improve teaching practices and increase student achievement. A review of the literature revealed the varying roles of instructional coaches including building relationships with teachers, improving teaching practices, and providing feedback to teachers. Additionally, literature examined highlighted the important role that school leaders play in planning and preparation when implementing an instructional coaching program, and the importance of careful hiring, training, and financial considerations. This qualitative research study examined the decisions that one Title I elementary school principal made when designing, implementing, monitoring and evaluating an instructional coaching program. The theoretical framework of instructional leadership anchored and organized this study. This dissertation study was conducted in one Title I elementary school in an urban school district that has made gains in student achievement over the past three years. Participants included the principal, two assistant principals who are involved in the instructional coaching program, two instructional coaches, and four teachers who have worked with an instructional coach or coaches. Data collected includes interviews with all participants, observations of interactions between participants, and the collection of artifacts. The key themes that emerged after the triangulation of the data were (a) instructional leadership driven decision-making, (b) instructional coaching support in the classroom, and (c) collaboration and preparation for collaboration. As more schools and principals consider instructional coaching as a framework for improving teaching practices and increasing student achievement, a sound understanding of the key instructional leadership driven decisions becomes increasingly essential. By gaining a full understanding of the practices of an effective instructional coaching program, school leaders have the potential of significantly and positively improving their school’s performance

    The field description model for the LHC quadrupole superconducting magnets

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    The LHC control system requires an accurate forecast of the magnetic field and the multipole field errors to reduce the burden on the beam-based feed-back. The Field Description for the LHC (FIDEL) is the core of this forecast system and is based on the identification and physical decomposition of the effects that contribute to the total field in the magnet apertures. The effects are quantified using the data obtained from series magnetic measurements at CERN and they are consequently modelled empirically or theoretically depending on the complexity of the physical phenomena. This paper presents a description of the methodology used to model the field of the LHC magnets particularly focusing on the results obtained for the LHC main quadrupoles (MQ) and insertion region wide aperture quadrupoles (MQY).peer-reviewe

    The dependence of the field decay on the powering history of the LHC superconducting dipole magnets

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    The decay of the allowed multipoles in the Large Hadron Collider (LHC) dipoles is expected to perturb the beam stability during the particle injection. The decay amplitude is largely affected by the powering history of the magnet and is particularly dependent on the pre-cycle flat-top current and duration as well as the pre-injection preparation duration. With possible prospects of having different genres of cycles during the LHC operation, the powering history effect must be taken into account in the Field Description Model for the LHC and must hence be corrected during machine operation. This paper presents the results of the modelling of this phenomenon.peer-reviewe

    Adaptation to Blue Light in Marine Synechococcus Requires MpeU, an Enzyme with Similarity to Phycoerythrobilin Lyase Isomerases

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    Marine Synechococcus has successfully adapted to environments with different light colors, which likely contributes to this genus being the second most abundant group of microorganisms worldwide. Populations of Synechococcus that grow in deep, blue ocean waters contain large amounts of the blue-light absorbing chromophore phycourobilin (PUB) in their light harvesting complexes (phycobilisomes). Here, we show that all Synechococcus strains adapted to blue light possess a gene called mpeU. MpeU is structurally similar to phycobilin lyases, enzymes that ligate chromophores to phycobiliproteins. Interruption of mpeU caused a reduction in PUB content, impaired phycobilisome assembly and reduced growth rate more strongly in blue than green light. When mpeU was reintroduced in the mpeU mutant background, the mpeU-less phenotype was complemented in terms of PUB content and phycobilisome content. Fluorescence spectra of mpeU mutant cells and purified phycobilisomes revealed red-shifted phycoerythrin emission peaks, likely indicating a defect in chromophore ligation to phycoerythrin-I (PE-I) or phycoerythrin-II (PE-II). Our results suggest that MpeU is a lyase-isomerase that attaches a phycoerythrobilin to a PEI or PEII subunit and isomerizes it to PUB. MpeU is therefore an important determinant in adaptation of Synechococcus spp. to capture photons in blue light environments throughout the world\u27s oceans

    Can we monitor heart attack in the troponin era: evidence from a population-based cohort study

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    <p>Abstract</p> <p>Background</p> <p>Troponins (highly sensitive biomarkers of myocardial damage) increase counts of myocardial infarction (MI) in clinical practice, but their impact on trends in admission rates for MI in National statistics is uncertain.</p> <p>Methods</p> <p>Cases coded as MI or other cardiac diagnoses in the Hospital Morbidity Data Collection (MI-HMDC) in Western Australia in 1998 and 2003 were classified using revised criteria for MI developed by an International panel convened by the American Heart Association (AHA criteria) using information on symptoms, ECGs and cardiac biomarkers abstracted from samples of medical notes. Age-sex standardized rates of MI-HMDC were compared with rates of MI based on AHA criteria including troponins (MI-AHA) or traditional biomarkers only (MI-AHAck).</p> <p>Results</p> <p>Between 1998 and 2003, rates of MI-HMDC decreased by 3.5% whereas rates of MI-AHA increased by 17%, a difference largely due to increased false-negative cases in the HMDC associated with marked increased use of troponin tests in cardiac admissions generally, and progressively lower test thresholds. In contrast, rates of MI-AHA<sub>ck </sub>declined by 18%.</p> <p>Conclusions</p> <p>Increasing misclassification of MI-AHA by the HMDC may be due to reluctance by clinicians to diagnose MI based on relatively small increases in troponin levels. These influences are likely to continue. Monitoring MI using AHA criteria will require calibration of commercially available troponin tests and agreement on lower diagnostic thresholds for epidemiological studies. Declining rates of MI-AHA<sub>ck </sub>are consistent with long-standing trends in MI in Western Australia, suggesting that neither MI-HMDC nor MI-AHA reflect the true underlying population trends in MI.</p

    The relationship between biological and psychosocial risk factors and resting‐state functional connectivity in 2‐monthold Bangladeshi infants: A feasibility and pilot study

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    Childhood poverty has been associated with structural and functional alterations in the developing brain. However, poverty does not alter brain development directly, but acts through associated biological or psychosocial risk factors (e.g. malnutrition, family conflict). Yet few studies have investigated risk factors in the context of infant neurodevelopment, and none have done so in low‐resource settings such as Bangladesh, where children are exposed to multiple, severe biological and psychosocial hazards. In this feasibility and pilot study, usable resting‐state fMRI data were acquired in infants from extremely poor (n = 16) and (relatively) more affluent (n = 16) families in Dhaka, Bangladesh. Whole‐brain intrinsic functional connectivity (iFC) was estimated using bilateral seeds in the amygdala, where iFC has shown susceptibility to early life stress, and in sensory areas, which have exhibited less susceptibility to early life hazards. Biological and psychosocial risk factors were examined for associations with iFC. Three resting‐state networks were identified in within‐group brain maps: medial temporal/striatal, visual, and auditory networks. Infants from extremely poor families compared with those from more affluent families exhibited greater (i.e. less negative) iFC in precuneus for amygdala seeds; however, no group differences in iFC were observed for sensory area seeds. Height‐for‐age, a proxy for malnutrition/infection, was not associated with amygdala/precuneus iFC, whereas prenatal family conflict was positively correlated. Findings suggest that it is feasible to conduct infant fMRI studies in low‐resource settings. Challenges and practical steps for successful implementations are discussed

    Focusing strength measurements of the main quadrupoles for the LHC

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    More than 1100 quadrupole magnets of different types are needed for the Large Hadron Collider (LHC) which is in the construction stage at CERN. The most challenging parameter to measure on these quadrupoles is the integrated gradient (Gdl). An absolute accuracy of 0.1% is needed to control the beta beating. In this paper we briefly describe the whole set of equipment used for Gdl measurements: Automated Scanner system, Single Stretched Wire system and Twin Coils system, concentrating mostly on their absolute accuracies. Most of the possible inherent effects that can introduce systematic errors are discussed along with their preventive methods. In the frame of this qualification some of the magnets were tested with two systems. The results of the intersystem cross-calibrations are presented. In addition, the qualification of the measurement system used at the magnet manufacturer's is based on results of more than 40 quadrupole assemblies tested in cold conditions at CERN and in warm conditions at the vendor site.peer-reviewe

    Effect of private insurance incentive policy reforms on trends in coronary revascularisation procedures in the private and public health sectors in Western Australia: A cohort study

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    Background: The Australian federal government introduced private health insurance incentive policy reforms in 2000 that increased the uptake of private health insurance in Australia. There is currently a lack of evidence on the effect of the policy reforms on access to cardiovascular interventions in public and private hospitals in Australia. The aim was to investigate whether the increased private health insurance uptake influenced trends in emergency and elective coronary artery revascularisation procedures (CARPs) for private and public patients. Methods: We included 34,423 incident CARPs from Western Australia during 1995-2008 in this study. Rates of emergency and elective CARPs were stratified for publicly and privately funded patients. The average annual percent change (AAPC) in trend was calculated before and after 2000 using joinpoint regression. Results: The rate of emergency CARPs, which were predominantly percutaneous coronary interventions (PCIs) with stenting, increased throughout the study period for both public and private patients (AAPC=12.9%, 95% CI=5.0,22.0 and 14.1%, 95% CI=9.8,18.6, respectively) with no significant difference in trends before and after policy implementation. The rate of elective PCIs with stenting from 2000 onwards remained relatively stable for public patients (AAPC=−6.0, 95% C= −16.9,6.4), but increased by 4.1% on average annually (95% CI=1.8,6.3) for private patients (Pdifference=0.04 between groups). This rate increase for private patients was only seen in people aged over 65 years and people residing in high socioeconomic areas.Conclusions: The private health insurance incentive policy reforms are a likely contributing factor in the shift in 2000 from public to privately-funded elective PCIs with stenting. These reforms as well as the increasing number of private hospitals may have been successful in increasing the availability of publicly-funded beds since 2000

    A cohort study: temporal trends in prevalence of antecedents, comorbidities and mortality in Aboriginal and non-Aboriginal Australians with first heart failure hospitalization, 2000-2009

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    Abstract Background/objectives: Little is known about trends in risk factors and mortality for Aboriginal Australians with heart failure (HF). This population-based study evaluated trends in prevalence of risk factors, 30-day and 1-year all-cause mortality following first HF hospitalization among Aboriginal and non-Aboriginal Western Australians in the decade 2000-2009. Methods: Linked-health data were used to identify patients (20-84 years), with a first-ever HF hospitalization. Trends in demographics, comorbidities, interventions and risk factors were evaluated. Logistic and Cox regression models were fitted to test and compare trends over time in 30-day and 1-year mortality. Results: Of 17,379 HF patients, 1,013 (5.8 %) were Aboriginal. Compared with 2000-2002, the prevalence (as history) of myocardial infarction and hypertension increased more markedly in 2006-2009 in Aboriginal (versus non-Aboriginal) patients, while diabetes and chronic kidney disease remained disproportionately higher in Aboriginal patients. Risk factor trends, including the Charlson comorbidity index, increased over time in younger Aboriginal patients. Risk-adjusted 30-day mortality did not change over the decade in either group. Risk-adjusted 1-year mortality (in 30-day survivors) was non-significantly higher in Aboriginal patients in 2006-2008 compared with 2000-2002 (hazard ratio (HR) 1.44; 95 % CI 0.85-2.41; p-trend = 0.47) whereas it decreased in non-Aboriginal patients (HR 0.87; 95 % CI 0.78-0.97; p-trend = 0.01). Conclusions: Between 2000 and 2009, the prevalence of HF antecedents increased and remained disproportionately higher in Aboriginal (versus non-Aboriginal) HF patients. Risk-adjusted 1-year mortality did not improve in Aboriginal patients over the period in contrast with non-Aboriginal patients. These findings highlight the need for better prevention and post-HF care in Aboriginal Australians
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