10 research outputs found
Folic acid-modified and functionalized CuS nanocrystal-based nanoparticles for combined tumor chemo- and photothermal therapy
No full textInfluence of drug transporters and stereoselectivity on the brain penetration of pioglitazone as a potential medicine against Alzheimer's disease
No full text
Novel Nanosized Chitosan-Betulinic Acid Against Resistant Leishmania Major and First Clinical Observation of such parasite in Kidney
No full textNanotechnology and Drug Delivery
No full textNowadays nanotechnology represents an expanding field that is providing powerfultools for the pharmaceutical industry such as polymeric, solid lipid, metallic, and magnetic NPs, liposomes, dendrimers, and other nanostructures. The development of nanopharmaceutics allows the understanding of some of the major mechanisms of current diseases on a molecular basis. Particularly, drug delivery mediated by nanosystems is relevant since NPs are able to reach the target organ and deliver the drug with a desirable profile according to the pathology needs, minimizing undesirable side effects. The main physicochemical properties of nanosystems are related with the increase in the surface-to-volume ratio of the particles, their permeability across biological barriers, and the surface modification of nanodevices. These parameters are relevant in drug loading and release and particularly for the targeted delivery to cells showing specific markers or receptors in the membrane surface.Fil: Islan, German Abel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Fermentaciones Industriales. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Fermentaciones Industriales; ArgentinaFil: Martin Saldaña, Sergio. Gihon Laboratorios Químicos SRL; ArgentinaFil: Chevalier, Merari Tumin. Gihon Laboratorios Químicos SRL; ArgentinaFil: Alvarez, Vera Alejandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata. Instituto de Investigaciones en Ciencia y Tecnología de Materiales. Universidad Nacional de Mar del Plata. Facultad de Ingeniería. Instituto de Investigaciones en Ciencia y Tecnología de Materiales; ArgentinaFil: Castro, Guillermo Raul. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Fermentaciones Industriales. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Fermentaciones Industriales; Argentin
Molecular decodification of gymnemic acids from Gymnema sylvestre. Discovery of a new class of liver X receptor antagonists
No full text
