141 research outputs found

    Inverse perturbation method for structural redesign with frequency and mode shape constraints

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76581/1/AIAA-8777-705.pd

    Nonlinear incremental inverse perturbation method for structural redesign

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76715/1/AIAA-1983-892-392.pd

    Admissible large perturbations in structural redesign

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76363/1/AIAA-10551-828.pd

    Higher than present global mean sea level recorded by an Early Pliocene intertidal unit in Patagonia (Argentina)

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    Reconstructions of global mean sea level from earlier warm periods in Earth?s history can helpconstrain future projections of sea level rise. Here we report on the sedimentology and age ofa geological unit in central Patagonia, Argentina, that we dated to the Early Pliocene(4.69?5.23 Ma, 2σ) with strontium isotope stratigraphy. The unit was interpreted as representativeof an intertidal environment, and its elevation was measured with differential GPS atca. 36m above present-day sea level. Considering modern tidal ranges, it was possible toconstrain paleo relative sea level within ±2.7m (1σ). We use glacial isostatic adjustmentmodels and estimates of vertical land movement to calculate that, when the Camaronesintertidal sequence was deposited, global mean sea level was 28.4 ± 11.7m (1σ) above present.This estimate matches those derived from analogous Early Pliocene sea level proxies inthe Mediterranean Sea and South Africa. Evidence from these three locations indicates thatEarly Pliocene sea level may have exceeded 20m above its present level. Such high globalmean sea level values imply an ice-free Greenland, a significant melting of West Antarctica,and a contribution of marine-based sectors of East Antarctica to global mean sea level.Fil: Rovere, Alessio. Universitat Bremen; AlemaniaFil: Pappalardo, Marta. Universidad de Pisa; ItaliaFil: Richiano, Sebastián Miguel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto Patagónico de Geología y Paleontología; ArgentinaFil: Aguirre, Marina Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo; ArgentinaFil: Sandstrom, Michael R.. Columbia University; Estados UnidosFil: Hearty, Paul J.. University of Texas at Austin; Estados UnidosFil: Austermann, Jacqueline. Columbia University; Estados UnidosFil: Castellanos, Ignacio. Universidad Nacional de La Plata; ArgentinaFil: Raymo, Maureen E.. Columbia University; Estados Unido

    An Early Pliocene relative sea level record from Patagonia (Argentina)

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    We report ciao a geological unit surveyed and dated in central Patagonia, Argentina (Camarones town, San Jorge Gulf). The unit was interpreted as representative of an intertidal environment and dated to the Early Pliocene (4.69-5.23 Ma) with strontium isotope stratigraphy. The elevation of this unit was measured with differential GPS at ca. 36 m above present-day sea level. Considering modern tidal ranges, it was possible to constrain paleo relative sea level within ±2.5m (1s). We use glacial isostatic adjustment models and estimates of vertical land movement to calculate that, when the Camarones intertidal sequence was deposited, global mean sea level was 28.4 ± 11.7m above present. This estimate matches those derived from analogous Early Pliocene sea level proxies in the Mediterranean Sea and South Africa. Evidence from these three locations indicates that Early Pliocene sea level may have exceeded 20m above its present level. Such high global mean sea level values imply an ice-free Greenland, a significant melting of West Antarctica, and a contribution of East Antarctica to global mean sea level.Los datos utilizados para este trabajo pueden accederse haciendo clic en "Documentos relacionados".Facultad de Ciencias Naturales y Muse

    Structural model correlation using large admissible perturbations incognate space

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76957/1/AIAA-10863-901.pd

    Children’s coping with in vivo peer rejection: An experimental investigation

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    We examined children's behavioral coping in response to an in vivo peer rejection manipulation. Participants (N=186) ranging between 10 and 13 years of age, played a computer game based on the television show Survivor and were randomized to either peer rejection (i.e., being voted out of the game) or non-rejection control. During a five-min. post-feedback waiting period children's use of several behavioral coping strategies was assessed. Rejection elicited a marked shift toward more negative affect, but higher levels of perceived social competence attenuated the negative mood shift. Children higher in depressive symptoms were more likely to engage in passive and avoidant coping behavior. Types of coping were largely unaffected by gender and perceived social competence. Implications are discussed. © 2006 Springer Science+Business Media, LLC

    An expansive human regulatory lexicon encoded in transcription factor footprints.

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    Regulatory factor binding to genomic DNA protects the underlying sequence from cleavage by DNase I, leaving nucleotide-resolution footprints. Using genomic DNase I footprinting across 41 diverse cell and tissue types, we detected 45 million transcription factor occupancy events within regulatory regions, representing differential binding to 8.4 million distinct short sequence elements. Here we show that this small genomic sequence compartment, roughly twice the size of the exome, encodes an expansive repertoire of conserved recognition sequences for DNA-binding proteins that nearly doubles the size of the human cis-regulatory lexicon. We find that genetic variants affecting allelic chromatin states are concentrated in footprints, and that these elements are preferentially sheltered from DNA methylation. High-resolution DNase I cleavage patterns mirror nucleotide-level evolutionary conservation and track the crystallographic topography of protein-DNA interfaces, indicating that transcription factor structure has been evolutionarily imprinted on the human genome sequence. We identify a stereotyped 50-base-pair footprint that precisely defines the site of transcript origination within thousands of human promoters. Finally, we describe a large collection of novel regulatory factor recognition motifs that are highly conserved in both sequence and function, and exhibit cell-selective occupancy patterns that closely parallel major regulators of development, differentiation and pluripotency
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