A Method to Separate Stochastic and Deterministic Information from Electrocardiograms

In this work we present a new idea to develop a method to separate stochastic and deterministic information contained in an electrocardiogram, ECG, which may provide new sources of information with diagnostic purposes. We assume that the ECG has information corresponding to many different processes related with the cardiac activity as well as contamination from different sources related with the measurement procedure and the nature of the observed system itself. The method starts with the application of an improuved archetypal analysis to separate the mentioned stochastic and deterministic information. From the stochastic point of view we analyze Renyi entropies, and with respect to the deterministic perspective we calculate the autocorrelation function and the corresponding correlation time. We show that healthy and pathologic information may be stochastic and/or deterministic, can be identified by different measures and located in different parts of the ECG.Comment: 4 pages, 6 figure

Educators’ Reflections on Empowerment in a Gender Responsive Program for Women Offenders

We explore women educators’ experiences teaching in a gender-responsive program for women who are incarcerated. Themes including fostering empowerment, motivations for teaching, and tensions teaching emancipatory content in jail

ResolanaPaving Paths Toward Transformation with Incarcerated Women

The purpose of this study was to elicit the experiences of women who participated in a gender-responsive program in jail. Results indicate the holistic programming and learning environment was an emancipatory container where transformation could occur through interpersonal and intrapersonal engagement. Findings have implications for the education of incarcerated women

Y-Aminobutyric acid inhibits synergistic interleukin-6 release and increases intracellular cytokine content in C6 astrocytoma cells in vitro

Alzheimer’s disease (AD) is a neurodegenerative disorder that is characterized by memory loss and is the most common cause of dementia. It is has been hypothesized that pro-inflammatory cytokines induce the inflammation that is believed to be the cause of the neuronal death that is associated with AD. γ-aminobutyric acid (GABA) is a major inhibitory neurotransmitter in the Central Nervous System possessing membrane hyperpolarization or depolarization activities. A decline in GABA may enhance cytokine release in Alzheimer’s disease resulting in neuroinflammation. Therefore, we investigated the GABA-mediated suppression of the synergistic release of interleukin-6 (IL-6) induced by interleukin 1- (IL-1) and tumor necrosis factor (TNF-). In this study our aim was to determine the sub-cellular location of the accumulated IL-6 within Rat C6 astrocytoma cells and to determine the receptor through which GABA is acting to cause the intracellular accumulation of IL-6. We hypothesize that the accumulation occurs within the Golgi apparatus and that the GABAB receptor is acted upon to inhibit the release of IL-6

Effect of Different Urine Cow Nitrogen Rates and Different Moisture Conditions on Nitrogen Mineralization in an Andisol from Southern Chile

Urea present in cattle urine contributes large amounts of nitrogen (N) to grazed pastures, which can be an equivalent to approximately 1000 kg N ha−1. However, there are no studies in volcanic soils of southern Chile on the effect of different concentrations of urinary N deposited in the soil, nor of different wetting and drying conditions mimicking the variation of weather conditions on the nitrification process, from urea to NH4+ and total oxidized nitrogen (TON), throughout time. In addition, the inhibition on nitrification driven by the accumulation of NH3 at high rates of N applied to an Andisol have not been evaluated. Fresh cattle urine was applied at three different rates of N equivalent to 247 kg N ha−1 (Low N), 461 kg N ha−1 (Medium N), 921 kg N ha−1 (High N), and de-ionized water as Control. Further, three moisture conditions were imposed: constant moisture (CM), drying-rewetting (DRW) cycles at 7 days interval, and soil drying (SD). Destructive soil cores samples were evaluated for top and bottom halves individually every 7 days over a 36-d period to measure changes on inorganic N and pH. There were no interaction effects for N rates and soil moisture. The main effect of the different rates of N on mineralization was significant throughout the incubation period, while the effect of the different moisture conditions was var-iable over time. The High N was associated with elevated NH3 concentrations and could explain that total N mineralization was partially inhibited. These results suggest that the presence of different nitrifying microorganisms in the soil under different chemical and physical conditions determines nitrification, thus, the oxidation of ammonia should be studied in more detail as the first step of nitrification, specifically in volcanic soils

Sensitivity Analysis and Quantification of the Role of Governing Transport Mechanisms and Parameters in a Gas Flow Model for Low-Permeability Porous Media

Recent models represent gas (methane) migration in low-permeability media as a weighted sum of various contributions, each associated with a given flow regime. These models typically embed numerous chemical/physical parameters that cannot be easily and unambiguously evaluated via experimental investigations. In this context, modern sensitivity analysis techniques enable us to diagnose the behavior of a given model through the quantification of the importance and role of model input uncertainties with respect to a target model output. Here, we rely on two global sensitivity analysis approaches and metrics (i.e., variance-based Sobol’ indices and moment-based AMA indices) to assess the behavior of a recent interpretive model that conceptualizes gas migration as the sum of a surface diffusion mechanism and two weighted bulk flow components. We quantitatively investigate the impact of (i) each uncertain model parameter and (ii) the type of their associated probability distribution on the evaluation of methane flow. We then derive the structure of an effective diffusion coefficient embedding all complex mechanisms of the model considered and allowing quantification of the relative contribution of each flow mechanism to the overall gas flow

The Simple Non-degenerate Relativistic Gas: Statistical Properties and Brownian Motion

This paper shows a novel calculation of the mean square displacement of a classical Brownian particle in a relativistic thermal bath. The result is compared with the expressions obtained by other authors. Also, the thermodynamic properties of a non-degenerate simple relativistic gas are reviewed in terms of a treatment performed in velocity space.Comment: 6 pages, 2 figure

Building a Shared Definitional Model of Long Duration Human Spaceflight

In 1956, on the eve of human space travel Strughold first proposed a simple classification of the present and future stages of manned flight that identified key factors, risks and developmental stages for the evolutionary journey ahead. As we look to optimize the potential of the ISS as a gateway to new destinations, we need a current shared working definitional model of long duration human space flight to help guide our path. Initial search of formal and grey literature augmented by liaison with subject matter experts. Search strategy focused on both the use of term long duration mission and long duration spaceflight, and also broader related current and historical definitions and classification models of spaceflight. The related sea and air travel literature was also subsequently explored with a view to identifying analogous models or classification systems. There are multiple different definitions and classification systems for spaceflight including phase and type of mission, craft and payload and related risk management models. However the frequently used concepts of long duration mission and long duration spaceflight are infrequently operationally defined by authors, and no commonly referenced classical or gold standard definition or model of these terms emerged from the search. The categorization (Cat) system for sailing was found to be of potential analogous utility, with its focus on understanding the need for crew and craft autonomy at various levels of potential adversity and inability to gain outside support or return to a safe location, due to factors of time, distance and location