NDVI Response to Satellite-Estimated Antecedent Precipitation in Dryland Pastures

Precipitation is a critical driver of vegetation productivity and dynamics in dryland environments, especially in areas with intense livestock farming. Availability and access to accurate, reliable, and timely rainfall data are essential for natural resources management, environmental monitoring, and informing hydrological rainfall-runoff models. Gauged precipitation data in drylands are often scarce, fragmented, and with low spatial resolution; therefore, satellite-estimated precipitation becomes a valuable dataset for overcoming this constraint. Using statistical indices, we compared satellite-derived precipitation data from four products (CHIRPS, GPM, TRMM, and PERSIANN-CDR) against gauged data at different temporal scales (daily, monthly, and yearly). Spatial correlations were calculated for GPM and CHIRPS estimates against interpolated gauged precipitation. We then estimated NDVI response to Antecedent Accumulated Precipitation (AAP) for 1, 3, 6, 9, and 12 months of four major vegetation types typical of the region. Statistical metrics varied with temporal scales being highest and acceptable for periods of 1 month or 1 year. At monthly scale GPM presented the best Pearson’s Correlation Coefficient (r), Root Mean Square Error (RMSE) and RMSE-observations standard deviation ratio (RSR) and CHIRPS resulted in lower Mean Error (ME) and Bias. On an annual basis CHIRPS showed the best adjustment for all indicators except for r. NDVI responses to 3 months of AAP were significant for all vegetation types in the study area. The findings of this study show that estimated precipitation data from GPM and CHIRPS satellites are accurate and valuable as a tool for analysing the relationships between precipitation and vegetation in the drylands of MendozaEEA Rama CaídaFil: Brieva, Carlos. University of Newcastle. School of Engineering. Centre for Water Security and Environmental Sustainability; AustraliaFil: Brieva, Carlos. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rama Caída; ArgentinaFil: Saco, Patricia, M. University of Newcastle. School of Engineering. Centre for Water Security and Environmental Sustainability; AustraliaFil: Sandi, Steven G. University of Newcastle. School of Engineering. Centre for Water Security and Environmental Sustainability; AustraliaFil: Sandi, Steven G. Deakin University. School of Engineering; AustraliaFil: Mora, Sebastián. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rama Caída; ArgentinaFil: Rodríguez, José F. University of Newcastle. School of Engineering. Centre for Water Security and Environmental Sustainability; Australi

Mitochondrial physiology

As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery

Mitochondrial physiology

As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery

Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever

Infection with Lassa virus (LASV) can cause Lassa fever, a haemorrhagic illness with an estimated fatality rate of 29.7%, but causes no or mild symptoms in many individuals. Here, to investigate whether human genetic variation underlies the heterogeneity of LASV infection, we carried out genome-wide association studies (GWAS) as well as seroprevalence surveys, human leukocyte antigen typing and high-throughput variant functional characterization assays. We analysed Lassa fever susceptibility and fatal outcomes in 533 cases of Lassa fever and 1,986 population controls recruited over a 7 year period in Nigeria and Sierra Leone. We detected genome-wide significant variant associations with Lassa fever fatal outcomes near GRM7 and LIF in the Nigerian cohort. We also show that a haplotype bearing signatures of positive selection and overlapping LARGE1, a required LASV entry factor, is associated with decreased risk of Lassa fever in the Nigerian cohort but not in the Sierra Leone cohort. Overall, we identified variants and genes that may impact the risk of severe Lassa fever, demonstrating how GWAS can provide insight into viral pathogenesis

The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance.

Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing in Africa over the past year has led to a major increase in the number of sequences that have been generated and used to track the pandemic on the continent, a number that now exceeds 100,000 genomes. Our results show an increase in the number of African countries that are able to sequence domestically and highlight that local sequencing enables faster turnaround times and more-regular routine surveillance. Despite limitations of low testing proportions, findings from this genomic surveillance study underscore the heterogeneous nature of the pandemic and illuminate the distinct dispersal dynamics of variants of concern-particularly Alpha, Beta, Delta, and Omicron-on the continent. Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve while the continent faces many emerging and reemerging infectious disease threats. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century

The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance

INTRODUCTION Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic. RATIONALE We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs). RESULTS Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants. CONCLUSION Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century

Calibration, validation and predictive capability of a wetland evolution model for subtropical estuaries.

School of Engineering, University of Newcastle, Callaghan, NSW, AustraliaCentro Universitario Rosario de Investigaciones Hidroambientales (CURIHAM)Consejo de Investigaciones de la Universidad Nacional de Rosari

Predicting Sea-level Rise and Infrastructure Effects on Coastal Wetlands

: Climate change predictions for Australia include an accelerated sea-level rise, wich challenges the survival of estuarine wetlands. Furthermore, coastal infrastructure poses and additional constraint on the adaptive capacity of these ecosystems. This paper presents results of wetland evolution based on hydro period and inundation depth experienced by vegetation, and computed using a hydrodynamic model. The application simulates the long-term evolution of wetland on the Hunter Estuary heavily constricted by infrastructure that is undergoing the effects of predicted accelerated sea-level rise. The wetland presents a vegetation zonation sequence mudflats –mangrove –saltmarsh from the seaward margin, but it also affected by compartmentalization due tu internal road embankments and culverts that effectively attenuates tidal inputs. Results of the modelo show that flow attenuation can play a major role in wetland hydrodynamics and that its effects can increase wetland vulnerability under climate change scenarios, particularly in situations where existing infrastructure affects the flow.School of Engineering, University of Newcastle, Callaghan, NSW, AustraliaDepartment of Environmental Sciences, Macquarie University, North Ride, AustraliaDepartamento de Hidráulica, Escuela de Ingenieria Civil, Fac. de Cs. Exactas, Ingenieria y Agrimensura, Universidad Nacional de RosarioConsejo de Investigaciones de la Universidad Nacional de Rosari

Incorporating Infrastructure and Vegetation Effects on Sea Level Rise Predictions in Low-Gradient Coastal Landscapes

At the regional and global scales, coastal management and planning for future sea level rise scenarios is typically supported by modelling tools that predict the expected inundation extent. These tools rely on a number of simplifying assumptions that, in some cases, may result in important overestimation or underestimation of the inundation extent. One of such cases is coastal wetlands, where vegetation strongly affects both the magnitude and the timing of inundation. Many coastal wetlands display other forms of flow restrictions due to, for example, infrastructure or drainage works, which also alters the inundation patterns. In this contribution we explore the effects of flow restrictions on inundation patterns under sea level rise conditions in coastal wetlands. We use a dynamic wetland evolution model that not only incorporates the effects of flow restrictions due to culverts, bridges and weirs as well as vegetation, but also considers that vegetation changes as a consequence of increasing inundation. We apply our model to a coastal wetland in Australia and compare predictions of our model to predictions using conventional approaches. We found that some restrictions accentuate detrimental effects of sea level rise while others moderate them. We also found that some management strategies based on flow redistribution that provide short term solution may result more damaging in the long term if sea level rise is considered.Civil and Env. Eng. University of Newcastle, Callaghan, NSW 2308, AustraliaDepartamento de Hidráulica, Escuela de Ingenieria Civil, Fac. de Cs. Exactas, Ingenieria y Agrimensura, Universidad Nacional de RosarioConsejo de Investigaciones de la Universidad Nacional de Rosari

Hydrodynamics, vegetation transition and geomorphology coevolution in a semi-arid floodplain wetland.

School of Engineering, University of Newcastle, Callaghan, NSW, AustraliaCentro Universitario Rosario de Investigaciones Hidroambientales (CURIHAM)Consejo de Investigaciones de la Universidad Nacional de RosarioScience Division, NSW Office of Environment and Heritage, Sydney, NSW, AustraliaEnvironmental Sciences, Macquarie University, Sydney, Australi