19 research outputs found

    Documentation of individualized preoperative risk assessment: a multi-center study

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    Background: Individual surgical risk assessment (ISRA) enhances patient care experience and outcomes by informing shared decision-making, strengthening the consent process, and supporting clinical management. Neither the use of individual pre-surgical risk assessment tools nor the rate of individual risk assessment documentation is known. The primary endpoint of this study was to determine the rate of physician documented ISRAs, with or without a named ISRA tool, within the records of patients with poor outcomes. Secondary endpoints of this work included the effects of age, sex, race, ASA class, and time and type of surgery on the rate of documented presurgical risk. / Methods: The records of non-obstetric surgical patients within 22 community-based private hospitals in Arizona, Colorado, Nebraska, Nevada, and Wyoming, between January 1 and December 31, 2017, were evaluated. A two-sample proportion test was used to identify the difference between surgical documentation and anesthesiology documentation of risk. Logistic regression was used to analyze both individual and group effects associated with secondary endpoints. / Results: Seven hundred fifty-six of 140,756 inpatient charts met inclusion criteria (0.54%, 95% CI 0.50 to 0.58%). ISRAs were documented by 16.08% of surgeons and 4.76% of anesthesiologists (p < 0.0001, 95% CI −0.002 to 0.228). Cardiac surgeons documented ISRAs more frequently than non-cardiac surgeons (25.87% vs 16.15%) [p = 0.0086, R-squared = 0.970%]. Elective surgical patients were more likely than emergency surgical patients (19.57 vs 12.03%) to have risk documented (p = 0.023, R-squared = 0.730%). Patients over the age of 65 were more likely than patients under the age of 65 to have ISRA documentation (20.31 vs 14.61%) [p = 0.043, R-squared = 0.580%]. Only 10 of 756 (1.3%) records included documentation of a named ISRA tool. / Conclusions: The observed rate of documented ISRA in our sample was extremely low. Surgeons were more likely than anesthesiologists to document ISRA. As these individualized risk assessment discussions form the bedrock of perioperative informed consent, the rate and quality of risk documentation must be improved

    The Universal Plausibility Metric (UPM) & Principle (UPP)

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    <p>Abstract</p> <p>Background</p> <p>Mere possibility is not an adequate basis for asserting scientific plausibility. A precisely defined universal bound is needed beyond which the assertion of <it>plausibility</it>, particularly in life-origin models, can be considered operationally falsified. But can something so seemingly relative and subjective as plausibility ever be quantified? Amazingly, the answer is, "Yes." A method of objectively measuring the plausibility of any chance hypothesis (The Universal Plausibility Metric [UPM]) is presented. A numerical inequality is also provided whereby any chance hypothesis can be definitively falsified when its UPM metric of ξ is < 1 (The Universal Plausibility Principle [UPP]). Both UPM and UPP pre-exist and are independent of any experimental design and data set.</p> <p>Conclusion</p> <p>No low-probability hypothetical plausibility assertion should survive peer-review without subjection to the UPP inequality standard of formal falsification (ξ < 1).</p

    Addressing the Desert Kites Phenomenon and Its Global Range Through a Multi-proxy Approach

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    International audienceThis paper argues that the wide geographical distribution of desert kites, which are huge archaeological structures of stone visible from satellite images, must be more broadly acknowledged as a momentous factor in the study of their variability and function. This is important so that researchers can more accurately understand and interpret their impact on biodiversity, landscapes and subsistence patterns. The first results and perspectives of the Globalkites research project are discussed and presented. Often considered as hunting traps, the kites could have also been used for animal husbandry. In a broader archaeological context, where kites seem to have been operating from the Neolithic to recent historical times, we propose an interdisciplinary approach at the crossroads of anthropology (archaeology and ethnology), geomatics and Geographic Information Systems (GIS), geostatistics, mathematics and computerized data processing and geoarchaeological and bioarchaeological sciences (isotope studies, paleoclimatology, archaeozoology…). The principal aims of the project are to clearly articulate the variability of the structures and their relationship with the function and chronology of the kites. It is also crucial to discuss the wide distribution of these structures across the Middle East and Central Asia as a global phenomenon and the ideas that explain the dispersal and movements of people and/or traditions must be addressed

    Biomedical Potential of Marine Natural Products

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