Effectiveness of mindfulness-based stress reduction training and drug therapy on quality of life in patients with irritable bowel syndrome in Shahrekord

Abstract: Background: Irritable bowel syndrome is a common gastrointestinal disorder that affects 20-10 percent of the population. The current research is performed to compare the effectiveness of two methods of Mindfulnessbased stress reduction training and drug therapy on quality of life in patients with irritable bowel syndrome. methods used: In this research, randomized clinical trial had three phases: pre-test, post-test and 4 months after the last intervention (follow up) was performed. The Sample consisted of 30 IBS-D patients were randomly selected according to Rome-II, III criteria and divided into two groups of mindfulness-based stress reduction training and drug therapy. The collected data were analyzed using Ancova test. Results: The results showed that there were significant differences between Mindfulness-based stress reduction training and drug therapy group in quality of life in patients with irritable bowel syndrome in post-test and follow up stage (p<0/05). Conclusion: The rapists should consider modern psychotherapy techniques such as Mindfulness-based stress reduction training therapy as potential methods for Improve the quality of life in patients with irritable bowel syndrome. [Kamal Solati Dehkordi, Masoud Nikfarjam, Somaye Sanaei. Effectiveness of mindfulness-based stress reduction training and drug therapy on quality of life in patients with irritable bowel syndrome in Shahrekord

The Role of SCM practices in Competitive Advantage and Firm Performance: A Mediating Role of Supply Chain Innovation and TQM

The present study aimed to propose a theoretical framework that elucidates the impact of supply chain management (SCM) practices on the competitive advantage and performance of firms while considering the mediating effects of supply chain innovation and total quality management (TQM). This research article employed a descriptive correlational methodology based on a questionnaire, complemented by structural equation modelling. The study involved the participation of 279 individuals, including managers, assistants, and supply chain experts from small and medium-sized enterprises. The study findings suggest that SCM practices significantly influence TQM, supply chain innovation, competitive advantage, and firm performance. Additionally, TQM has a significant effect on supply chain innovation, competitive advantage, and firm performance. Similarly, supply chain innovation has a positive and significant impact on competitive advantage and firm performance. Furthermore, the positive and significant mediating role of supply chain innovation and TQM in the effect of SCM practices on competitive advantage and firm performance was observed. Therefore, it can be concluded that SCM practices enhance firm performance and competitive advantage through the improvement of supply chain innovation and TQM

The Role of SCM practices in Competitive Advantage and Firm Performance: A Mediating Role of Supply Chain Innovation and TQM

The present study aimed to propose a theoretical framework that elucidates the impact of supply chain management (SCM) practices on the competitive advantage and performance of firms while considering the mediating effects of supply chain innovation and total quality management (TQM). This research article employed a descriptive correlational methodology based on a questionnaire, complemented by structural equation modelling. The study involved the participation of 279 individuals, including managers, assistants, and supply chain experts from small and medium-sized enterprises. The study findings suggest that SCM practices significantly influence TQM, supply chain innovation, competitive advantage, and firm performance. Additionally, TQM has a significant effect on supply chain innovation, competitive advantage, and firm performance. Similarly, supply chain innovation has a positive and significant impact on competitive advantage and firm performance. Furthermore, the positive and significant mediating role of supply chain innovation and TQM in the effect of SCM practices on competitive advantage and firm performance was observed. Therefore, it can be concluded that SCM practices enhance firm performance and competitive advantage through the improvement of supply chain innovation and TQM

The Role of SCM practices in Competitive Advantage and Firm Performance: A Mediating Role of Supply Chain Innovation and TQM

The present study aimed to propose a theoretical framework that elucidates the impact of supply chain management (SCM) practices on the competitive advantage and performance of firms while considering the mediating effects of supply chain innovation and total quality management (TQM). This research article employed a descriptive correlational methodology based on a questionnaire, complemented by structural equation modelling. The study involved the participation of 279 individuals, including managers, assistants, and supply chain experts from small and medium-sized enterprises. The study findings suggest that SCM practices significantly influence TQM, supply chain innovation, competitive advantage, and firm performance. Additionally, TQM has a significant effect on supply chain innovation, competitive advantage, and firm performance. Similarly, supply chain innovation has a positive and significant impact on competitive advantage and firm performance. Furthermore, the positive and significant mediating role of supply chain innovation and TQM in the effect of SCM practices on competitive advantage and firm performance was observed. Therefore, it can be concluded that SCM practices enhance firm performance and competitive advantage through the improvement of supply chain innovation and TQM.</p

Growing Rats Are Resistant to Bone Loss Associated With Short-Term Hypercholesterolemia: A Preliminary Experimental Study: Rats Are Resistant to Bone Loss

We aimed to evaluate the potential of growing rats as a model of osteoporosis induced by short term hypercholesterolemia. Twelve growing female Sprague-Dawley rats were randomly allocated into two groups. Control rats received standard diet while rats in group 2 were fed with diet contained 20% sunflower oil, 2% cholesterol and 0.5% cholic acid for 2 weeks and then a diet contained 10% sunflower oil, 1% cholesterol and 0.25% cholic acid for the next 4 weeks. At the end of second week, serum total cholesterol level was assayed which was repeated at the end of the 6th week along with serum carboxy-terminal collagen crosslinks (CTX) and procollagen type 1 N propeptide (PINP) levels. Finally, rats were euthanized and right and left tibiae were dissected for histomorphometric study and determination of bone mineral density, respectively. Hypercholesterolemia was present in rats of group 2 in both sampling times. No significant difference was observed in body weight, epiphyseal and metaphyseal histomorphometric parameters and mineral density as well as serum CTX and PINP. Although this was a preliminary study with relatively low sample size, it seems that growing female Sprague-Dawley rats do not show bone loss due to short term hypercholesterolemia and may not be a proper animal model in this regard

International Nosocomial Infection Control Consortium report, data summary of 50 countries for 2010-2015: Device-associated module

•We report INICC device-associated module data of 50 countries from 2010-2015.•We collected prospective data from 861,284 patients in 703 ICUs for 3,506,562 days.•DA-HAI rates and bacterial resistance were higher in the INICC ICUs than in CDC-NHSN's.•Device utilization ratio in the INICC ICUs was similar to CDC-NHSN's. Background: We report the results of International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2010-December 2015 in 703 intensive care units (ICUs) in Latin America, Europe, Eastern Mediterranean, Southeast Asia, and Western Pacific. Methods: During the 6-year study period, using Centers for Disease Control and Prevention National Healthcare Safety Network (CDC-NHSN) definitions for device-associated health care-associated infection (DA-HAI), we collected prospective data from 861,284 patients hospitalized in INICC hospital ICUs for an aggregate of 3,506,562 days. Results: Although device use in INICC ICUs was similar to that reported from CDC-NHSN ICUs, DA-HAI rates were higher in the INICC ICUs: in the INICC medical-surgical ICUs, the pooled rate of central line-associated bloodstream infection, 4.1 per 1,000 central line-days, was nearly 5-fold higher than the 0.8 per 1,000 central line-days reported from comparable US ICUs, the overall rate of ventilator-associated pneumonia was also higher, 13.1 versus 0.9 per 1,000 ventilator-days, as was the rate of catheter-associated urinary tract infection, 5.07 versus 1.7 per 1,000 catheter-days. From blood cultures samples, frequencies of resistance of Pseudomonas isolates to amikacin (29.87% vs 10%) and to imipenem (44.3% vs 26.1%), and of Klebsiella pneumoniae isolates to ceftazidime (73.2% vs 28.8%) and to imipenem (43.27% vs 12.8%) were also higher in the INICC ICUs compared with CDC-NHSN ICUs. Conclusions: Although DA-HAIs in INICC ICU patients continue to be higher than the rates reported in CDC-NSHN ICUs representing the developed world, we have observed a significant trend toward the reduction of DA-HAI rates in INICC ICUs as shown in each international report. It is INICC's main goal to continue facilitating education, training, and basic and cost-effective tools and resources, such as standardized forms and an online platform, to tackle this problem effectively and systematically

International Nosocomial Infection Control Consortiu (INICC) report, data summary of 43 countries for 2007-2012. Device-associated module

We report the results of an International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2007-December 2012 in 503 intensive care units (ICUs) in Latin America, Asia, Africa, and Europe. During the 6-year study using the Centers for Disease Control and Prevention's (CDC) U.S. National Healthcare Safety Network (NHSN) definitions for device-associated health care–associated infection (DA-HAI), we collected prospective data from 605,310 patients hospitalized in the INICC's ICUs for an aggregate of 3,338,396 days. Although device utilization in the INICC's ICUs was similar to that reported from ICUs in the U.S. in the CDC's NHSN, rates of device-associated nosocomial infection were higher in the ICUs of the INICC hospitals: the pooled rate of central line–associated bloodstream infection in the INICC's ICUs, 4.9 per 1,000 central line days, is nearly 5-fold higher than the 0.9 per 1,000 central line days reported from comparable U.S. ICUs. The overall rate of ventilator-associated pneumonia was also higher (16.8 vs 1.1 per 1,000 ventilator days) as was the rate of catheter-associated urinary tract infection (5.5 vs 1.3 per 1,000 catheter days). Frequencies of resistance of Pseudomonas isolates to amikacin (42.8% vs 10%) and imipenem (42.4% vs 26.1%) and Klebsiella pneumoniae isolates to ceftazidime (71.2% vs 28.8%) and imipenem (19.6% vs 12.8%) were also higher in the INICC's ICUs compared with the ICUs of the CDC's NHSN