New palladium(II) and platinum(II) 5,5-diethylbarbiturate complexes with 2-phenylpyridine, 2,2’-bipyridine and 2,2’-dipyridylamine : synthesis, structures, DNA binding, molecular docking, cellular uptake, antioxidant activity and cytotoxicity

Peer reviewedPostprin

High-Throughput Calculation Workflows for Solid State Systems

The automation of calculations is key for high-throughput computational screening which can accelerate materials discovery and characterisation for a myriad of applications. These include Johnson Matthey’s areas of expertise such as catalysts for exhaust emissions control and hydrogen production via water electrolysis. An introduction to high-throughput computational screening and water electrolysis is provided in Chapter 1 of this thesis as well as a review of recent literature. We have used the AiiDA workflow manager to create material-agnostic workflows for high-throughput CASTEP density functional theory calculations of materials' properties. These workflows can automate various calculations including convergence testing, density of states, band structure, phonon, and defect calculations. In addition to running these calculations, our workflows automate the analysis of these results including the plotting of results. Some of the plots are simulated spectra which cover both electronic and vibrational spectroscopy techniques, and can be compared to experimental spectra to aid the characterisation of new materials. More details can be found in Chapter 3 of this thesis along with other computational methodology used in this work. An overview of the fundamental theory is given in Chapter 2. Chapter 4 contains the results of workflow testing with rutile TiO\textsubscript{2}, a widely studied photocatalyst, as well as Fe for its magnetic properties. In Chapter 5 we discuss our work on CeO\textsubscript{2} and ZrO\textsubscript{2}, two oxides that are used for oxygen storage in catalytic converters. Our work on mixed rutile oxides for water electrolysis is presented in Chapter 6, and Chapter 7 provides the summary and conclusions of the thesis as well as possible directions for future work

The development of plans for a national airport for Ankara, Turkey

\u27The present rapid development of general interest in aviation has brought to the front a new field of engineering. Development of the airplane has already reached a stage where the limit of its usefulness seems fixed only by the places which may be provided for taking off and landing. Due to the newness of the problem, not every one on whom responsibility rests recognizes the fact that the selection of the proper site and location for an airport is just as much an engineering problem as are its design and construction.\u27 The Turkish government began construction or the Ankara-Esenboga airport in 1949. The present airport has many disadvantages over the ideal situation. The runways are located about 20 degrees off the prevailing winds of the wind rose, which creates crosswinds on the runways and is very unsatisfactory for a class 4 airport. The location of the runways introduced an uneconomical excavation problem. The taxiways cross the main runways at four locations, which congests the take off and landing traffic. The overall length of the taxiway is great and adds more expense to the airport. The purpose of this thesis is to show that a more economical and advantageous design could have been had for an airport in this locality. The thesis submitted discusses this problem from several points of view as well as the actual location and design of runway and taxiway according to the new and modern specification of U.S. Civil Aeronautics Administration. Not considered in this paper is the design of hangars, administration building and other auxiliaries which is in fact a totally different field. That design is left for structural Engineers to work out --Foreword, pages 1-2

Design of non-fragile state estimators for discrete time-delayed neural networks with parameter uncertainties

This paper is concerned with the problem of designing a non-fragile state estimator for a class of uncertain discrete-time neural networks with time-delays. The norm-bounded parameter uncertainties enter into all the system matrices, and the network output is of a general type that contains both linear and nonlinear parts. The additive variation of the estimator gain is taken into account that reflects the possible implementation error of the neuron state estimator. The aim of the addressed problem is to design a state estimator such that the estimation performance is non-fragile against the gain variations and also robust against the parameter uncertainties. Sufficient conditions are presented to guarantee the existence of the desired non-fragile state estimators by using the Lyapunov stability theory and the explicit expression of the desired estimators is given in terms of the solution to a linear matrix inequality. Finally, a numerical example is given to demonstrate the effectiveness of the proposed design approach

Analiza učestalosti goveđeg beta-kazeina tipa A1 i A2 u krava holštajnsko-frizijske pasmine PCR-om u stvarnom vremenu s fluorescentnim hibridizacijskim sondama

A2 milk popularity is increasing across the world and novel molecular techniques have been evaluated to develop reliable methods. This study aimed to genotype Holstein-Friesian cows concerning their A1/A2 status using Real-time PCR assay with the specifically designed FRET hybridization probes. In this context, DNA samples were obtained from 310 Holstein-Friesian milk samples. Concerning the Real-time PCR assay, the melting temperature of each amplicon was analyzed and the melting data was converted to a derivative plot using the LightCycler 480 System. The sensor probe was designed to match the wild-type sequence in the target DNA. In the Real-time PCR assay, the melting peaks obtained in the Real-time PCR assay were highly decisive and consistent for each genotype regarding CCT→CAT alteration. The results indicated a remarkably high frequency of the A2 allele (68%) and a considerable frequency of heterozygous animals (0.41). Population genetic analysis showed intermediate levels of genetic variability and biodiversity. The A2-herd conversion process is a complex process consisting of genetic testing of both cows and calves, evaluating replacement rates, and the conversion of heterozygotes by using A2-genotyped bull semen. In this sense, the key point is a reliable and rapid genotyping method to produce A1-free milk. This study suggests that Real-time PCR assay with the specifically designed FRET hybridization probes is a preferable method for A2 genotyping, and may be useful for further studies and instructive for companies or breeders who aim to produce A2 milk.Popularnost mlijeka s A2 tipom beta-kazeina sve je veća diljem svijeta što je popraćeno razvojem novih i pouzdanijih metoda za molekularne analize. Cilj je ovog istraživanja bila genotipizacija holštajnsko-frizijskih krava s obzirom na A1/A2 status primjenom PCR-a u stvarnom vremenu (RT-PCR) s posebno dizajniranim FRET hibridizacijskim sondama. DNA je dobivena iz uzoraka mlijeka 310 krava. RT-PCR-om analizirana je temperatura taljenja svakog amplikona te su ti podaci uz upotrebu sustava LightCycler 480 korišteni za iscrtavanje grafičkih prikaza. Senzorska sonda dizajnirana je tako da odgovara divljem tipu sekvencije u ciljnoj DNA. Vršne vrijednosti taljenja dobivene RTPCR-om bile su postojane razlučivosti za svaki genotip s obzirom na promjenu CCT→CAT. Rezultati su pokazali vrlo visoku učestalost alela A2 (68 %) i znakovitu učestalost heterozogotnih životinja (0,41). Genetska analiza u populaciji pokazala je srednje vrijednosti genetske varijabilnosti i bioraznolikosti. Proces usmjeravanja uzgoja prema životinjama s A2 tipom mlijeka složen je proces koji uključuje genetsko testiranje krava i teladi, procjenu stopa zamjene i konverziju heterozigota upotrebom A2-genotipiziranog sjemena bikova. U tom je smislu ključna brza i pouzdana metoda genotipizacije životinja koje proizvode mlijeko bez A1 tipa beta-kazeina. Ovo istraživanje pokazuje da se RT-PCR s posebno dizajniranim hibridizacijskim FRET sondama može preporučiti za A2 genotipizaciju goveda. Navedena metoda mogla bi biti korisna u daljnjim istraživanjima te u industriji i u uzgoju stada za proizvodnju mlijeka s A2 tipom beta-kazeina

Assessments of Teachers’ Retention Strategies in Public and Private Secondary Schools in Manyara Region

This study is aimed to explore the teachers’ retention strategies between the private and public secondary schools in Babati Town council. The study was guided by four research objectives which were (i) To assess the factors affecting the job turnover for teachers in government schools in Babati Town council (ii) To assess the retention strategies used by the community to enhance teachers’ retention (iii) To compare the retention strategies used by private and public schools administrators to enhance teachers’ retention (iv) To assess the role of students in enhancing teachers’ retention. The study used both qualitative and quantitative approach where the sample of 191 respondents of different categories was interviewed and the data of the study was collected through structured questionnaires and semi-structured interviews. Simple random sampling was used to select the respondent of the study. The key findings of the study indicated that low salary, distance from home to school, lack of motivation, lack of morale and poor respect of teaching profession as well as lack profession development were the major reasons which cause teachers turnover in many government schools in Babati Town council. Also the study showed that the community have great role of making teachers to remains in schools if they were incorporated. Furthermore, the study showed that the private schools have managed to retain teachers because their administrators motivate them by providing extra duty allowance, giving them housing and rewarding top performers. It was concluded that in order the government schools to perform better they should have good and enough teachers in all teaching subjects. Therefore, this study recommends that if the government wants to retain teachers and to compete with private schools, the government should increase teacher’s salary so as to commensurate with their qualifications

ANALISIS PENGEMBANGAN KOTA BERDASARKAN KONDISI FISIK WILAYAH KOTA MASOHI IBUKOTA KABUPATEN MALUKU TENGAH

Dua hal penting dalam perkembangan kota, yaitu pertama; Menyangkut perubahan yang dikehendaki untuk memenuhi kebutuhan prasarana kota dan fasilitas hidup yang mengikat seiring perkembangan penduduk, kedua; menyangkut perluasan kota, sebab perkembangan ruang kota menuntut adanya ruang yang luas namun keterbatasan ruang yang merupakan kendala yang tak terhindarkan sehingga cenderung dilakukan konsolidasi dan pencadangan lahan serta peremajaan kota.Kota Masohi memiliki potensi yang sangat strategis baik dari segi posisi kewilayahan yang berada pada simpul pergerakan transportasi di daerah Kepulauan Seram yang dapat memicu perkembangan arus penduduk dalam jumlah besar, kemudian dari segi Historis yang merupakan ibukota kabupaten induk dari kedua kabupaten pemekaran yang menghimpit Kota Masohi dengan kondisi perkembangan yang telah ada baik itu ketersediaan sarana dan prasarana wilayah maupun kemampuan dalam mengelola sebuah perkotaan sehingga ketergantungan pada daerah ini masih sangat besar. Dengan melihat potensi-potensi tersebut, maka Kota Masohi memiliki beban yang bukan hanya dari dalam saja akan tetapi mendapat beban dari luar sehingga perkembangan wilayah secara fisik dirasakan sangat meningkat, sementara kondisi fisik wilayah kota memiliki beberapa keterbatasan dan kendala dalam perluasan wilayah kota dengan adanya beberapa faktor pembatas tersebut

ANALISIS POSTUR KERJA PADA SECTION MAINTENANCE TIRE DENGAN MENGGUNAKAN METODE WORKPLACE ERGONOMIC RISK ASSESSMENT (WERA) (STUDI KASUS: PT. RIUNG MITRA LESTARI SITE EMBALUT)

PT. Riung Mitra Lestari Site Embalut merupakan perusahaan kontraktor pertambangan batubara sebagai penunjang ketersediaan dan pemeliharaan alat berat. Salah satu aktivitas pemeliharaan alat berat yaitu section maintenance tire. Berdasarkan observasi, pada aktivitas section maintenance postur kerja dilakukan secara membungkuk dan berjongkok mengakibatkan keluhan MSDs pada pinggang dan punggung. Berdasarkan permasalahan, dilakukan analisis postur kerja menggunakan metode WERA. Dari 20 aktivitas terdapat 4 aktivitas mendapatkan action high yaitu pelepasan dan pemasangan nut tire dengan score 50 (92,60%), pemasangan tire dengan score 48 (88,90%), dan pemasangan bead seat band, o-ring, dan lockring dengan score 49 (90,70%). Diberikan usulan perbaikan yaitu alat fasilitas kerja dan postur kerja menggunakan simulasi software CATIA V5. Pada pelepasan dan pemasangan nut tire, diperoleh hasil 26 (48,15%) dengan action low. Pada pemasangan tire, diperoleh hasil 25 (46,29%) dengan action low. Dan pada pemasangan bead seat band, o-ring, dan lockring diperoleh hasil dari 31 (57,40%) dengan action medium