Comprehensive cosmographic analysis by Markov Chain Method

We study the possibility to extract model independent information about the dynamics of the universe by using Cosmography. We intend to explore it systematically, to learn about its limitations and its real possibilities. Here we are sticking to the series expansion approach on which Cosmography is based. We apply it to different data sets: Supernovae Type Ia (SNeIa), Hubble parameter extracted from differential galaxy ages, Gamma Ray Bursts (GRBs) and the Baryon Acoustic Oscillations (BAO) data. We go beyond past results in the literature extending the series expansion up to the fourth order in the scale factor, which implies the analysis of the deceleration, q_{0}, the jerk, j_{0} and the snap, s_{0}. We use the Markov Chain Monte Carlo Method (MCMC) to analyze the data statistically. We also try to relate direct results from Cosmography to dark energy (DE) dynamical models parameterized by the Chevalier-Polarski-Linder (CPL) model, extracting clues about the matter content and the dark energy parameters. The main results are: a) even if relying on a mathematical approximate assumption such as the scale factor series expansion in terms of time, cosmography can be extremely useful in assessing dynamical properties of the Universe; b) the deceleration parameter clearly confirms the present acceleration phase; c) the MCMC method can help giving narrower constraints in parameter estimation, in particular for higher order cosmographic parameters (the jerk and the snap), with respect to the literature; d) both the estimation of the jerk and the DE parameters, reflect the possibility of a deviation from the LCDM cosmological model.Comment: 24 pages, 7 figure

Carcinoma mucoepidermoide della base della lingua

Mucoepidermoid carcinoma (MEC) is the most common malignant, locally-invasive tumour of the salivary glands, and accounts for approximately 35% of all malignancies of the major and minor salivary gland. Minor salivary glands are scattered in different areas of the oral cavity such as palate, retromolar area, floor of the mouth, buccal mucosa, lips and tongue. MECs of tongue base are not common. We present a rare case of MEC localised at the tongue base in a 42-year-old Caucasian woman and discuss the histopathological types, management and review the literature. Adequate intra-oral excision was the treatment of choice in this case and in low-grade MEC. Prognosis of MEC is a function of the histological grade, adequacy of excision and clinical staging. © 2015, Pacini Editore s.r.l. All rights reserved

Explosion Behavior of Ethanol-Ethyl Acetate/Air Mixtures

Alcohol-ester mixtures and, among them, ethanol-ethyl acetate mixtures are widely used as solvents in the packaging industry. For the safe use of such mixtures, it is essential to characterize their explosion behavior. Specifically, knowledge is required about maximum pressure and the maximum rate of pressure rise (i.e., the deflagration index), which are among the most important parameters for the assessment of process hazards and the safe design of process equipment. To this aim, in this work, closed-vessel explosion tests were carried out for an ethanol-ethyl acetate composition (mole fraction of ethanol in ethanol + ethyl acetate equal to 0.62) of interest to the packaging industry, varying the fuel/air equivalence ratio from 1.0 to 1.7. Tests were also extended to ethanol/air and ethyl acetate/air to quantify the effects of the possible interaction between the two fuels in the mixture. All tests started from 25°C and 1 bar. Experimental results show that, as the fuel equivalence ratio is increased, a transition occurs from a regime in which synergistic effects arise making the explosion behavior of ethanol-ethyl acetate more severe (i.e., making the rate of explosion pressure rise of ethanol-ethyl acetate higher) than both ethanol and ethyl acetate, to a regime in which, as a result of a completely different interaction between ethanol and ethyl acetate, the explosion behavior of their mixture is less severe than both the individual components. The maximum rate of pressure rise falls within an intermediate regime in which non-linear interaction effects substantially disappear and, thus, the value of deflagration index for the mixture can be obtained by averaging the values of the two fuels according to their molar proportions

Delineating a new critical region for juvenile myoclonic epilepsy at the 22q11.2 chromosome

No abstract availabl

Surgical management of pleomorphic adenoma of parotid gland in elderly patients: Role of morphological features.

The neoplasms of the salivary glands account for 2% of head and neck tumors and the most common form is the Pleomorphic Adenoma (PA). Parotid gland is affected from 80% to 90% of cases. In elderly this tumors occurs mostly in females. These benign tumors are composed of epithelial and myoepithelial cells that are arranged with various morphological patterns and subtypes. The classification of these tumors is also based on the amount and nature of the stroma. In literature there is a almost complete consensus that, in the major salivary glands, PAs are enclosed by a layer of fibrous tissue often called "capsule" but there is disagreement about the form, extention and thickness of this layer. The treatment is surgical and there are two main different surgical approaches: an enucleation (local dissection) or so-called subtotal superficial parotidectomy and lateral or superficial total parotidectomy. Histopathological characteristics of PAs especially of capsular alterations such as thin capsule areas, capsule-free regions, capsule penetration, satellite nodules and pseudopodia in the different subtypes are important for the choice of surgical treatment and the first explanation for tumor recurrence. In our study we describe a morphological features of 84 cases of pleomorphic adenoma of parotid gland from elderly patients treated by a surgical "enucleation like" method called nucleoresection

Analysis of nucleotide diversity of NAT2 coding region reveals homogeneity across Native American populations and high intra-population diversity.

N-acetyltransferase 2 (NAT2), an important enzyme in clinical pharmacology, metabolizes antibiotics such as isoniazid and sulfamethoxazole, and catalyzes the transformation of aromatic and heterocyclic amines from the environment and diet into carcinogenic intermediates. Polymorphisms in NAT2 account for variability in the acetylator phenotype and the pharmacokinetics of metabolized drugs. Native Americans, settled in rural areas and large cities of Latin America, are under-represented in pharmacogenetics studies; therefore, we sequenced the coding region of NAT2 in 456 chromosomes from 13 populations from the Americas, and two from Siberia, detecting nine substitutions and 11 haplotypes. Variants *4 (37%), *5B (23%) and *7B (24%) showed high frequencies. Average frequencies of fast, intermediate and slow acetylators across Native Americans were 18, 56 and 25%, respectively. NAT2 intra-population genetic diversity for Native Americans is higher than East Asians and similar to the rest of the world, and NAT2 variants are homogeneously distributed across native populations of the continent

H-BIM – Innovative and Digital Tools to Improve the Management of the Existing Buildings

With the introduction of the BIM methodology, the digitalization is consolidating mostly the process of new building design defining new standardized working procedures in order to optimize the data flow. On the contrary, pertaining to existing buildings, the rules are still dictated by the traditional methodology leading to fragmented and disaggregated information flow. However, some tools have been recently developed and are quickly upgrading to meet the specific aim to pursue progress, dynamism and experimentation in order to stay in tune with market demands. One common issue, is due to the fact that the documents are paper, hard to find and numerous so that the digitalization represents the best real solution to improve their management. In this regard, the heart of the informative flow is represented by the Common Data Environment (CDE), a cloud storage in which the documents are collected once uploaded and easily manageable with specific platforms. By way of example, a case study is developed in the paper in which the management process of the H-BIM of the XV century’s structure placed in the old town of Naples is carried out in a digital way, through the usBIM.platform (released by ACCA software company) using specific tools, like links, markers and tags. The goal of the paper is to define both a new organization for the data archive, in which the documents are structured and easily traceable, both a new way of conceiving the BIM model that it is thought as an informative vehicle and a key access to the information rather than a mere geometric representation

Identità e relazioni sociali. Dai popoli migranti alla cultura del Web 2.0

Nel saggio è una riflessione preliminare su cos'è da intendere per identità prima di individuare il ruolo che svolge la comunicazione non solo nel mantenere ma anche e soprattutto nel costruire identità e nel gestire relazioni, nel senso di crearle, mutarle o annullarle.The essay is a reflection about identity and role of communication on creating, mantaining and destroying social relations