The ontology of causal process theories

There is a widespread belief that the so-called process theories of causation developed by Wesley Salmon and Phil Dowe have given us an original account of what causation really is. In this paper, I show that this is a misconception. The notion of "causal process" does not offer us a new ontological account of causation. I make this argument by explicating the implicit ontological commitments in Salmon and Dowe's theories. From this, it is clear that Salmon's Mark Transmission Theory collapses to a counterfactual theory of causation, while the Conserved Quantity Theory collapses to David Fair's phsyicalist reduction of causation

Intermediate range chemical ordering of cations in simple molten alkali halides

The presence of first sharp diffraction peaks in the partial structure factors is investigated in computer simulations of molten mixtures of alkali halides. An intermediate range ordering appears for the Li+ ions only, which is associated with clustering of this species and is not reflected in the arrangement of other ions. This ordering is surprising in view of the simplicity of the interionic interactions in alkali halides. The clustering reflects an incomplete mixing of the various species on a local length scale, which can be demonstrated by studying the complementary sub-space of cations in the corresponding pure alkali halides by means of a void analysis.Comment: 5 pages, 5 figure

The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells.

Thymocytes must bind major histocompatibility complex (MHC) proteins on thymic epithelial cells in order to mature into either CD8+ cytotoxic T cells or CD4+ helper T cells. Thymic precursors express both CD8 and CD4, and it has been suggested that the intracellular signals generated by CD8 or CD4 binding to class I or II MHC, respectively, might influence the fate of uncommitted cells. Here we test the notion that intracellular signaling by CD4 directs the development of thymocytes to a CD4 lineage. A hybrid protein consisting of the CD8 extracellular and transmembrane domains and the cytoplasmic domain of CD4 (CD884) should bind class I MHC but deliver a CD4 intracellular signal. We find that expression of a hybrid CD884 protein in thymocytes of transgenic mice leads to the development of large numbers of class I MHC-specific, CD4 lineage T cells. We discuss these results in terms of current models for CD4 and CD8 lineage commitment

OPENING REMARKS—TWELFTH VERTEBRATE PEST CONFERENCE

On behalf of the Vertebrate Pest Council, welcome to the 12th Vertebrate Pest Conference. Every other year since 1962, the Vertebrate Pest Council has sponsored the conference with the primary objective of bringing individuals interested in vertebrate pest control together to discuss problems and solutions of mutual concern. The main objectives of the conference are: 1. To exchange information on vertebrate pest management and related matters. 2. To advance environmentally safe vertebrate pest management methodologies. 3. To build cooperation with public and private agencies in solving vertebrate pest problems. 4. To consider and promote discussion and interaction among agencies and others about problems of mutual concern in the field of vertebrate pest management. 5. To foster educational work in vertebrate pest management. 6. To encourage research by both public and private agencies on vertebrate pest problems and their solutions. 7. To promote uniformity and coordination of activities among agencies and individuals concerned with the regulatory aspects of vertebrate pest management

WILDLIFE DAMAGE IN AUSTRALIA: CONSTRUCTIVE CONTRASTS WITH THE UNITED STATES

There are numerous wildlife damage problems in Australia. The major pests include rabbits (Oryctolagus cuniculusl, foxes (Vulpes vulpes/, starlings (Sturnus vulgarisl, feral cats (felts catus/, donkeys (Equus asinusl, goats (Capra hircusl, buffalo (Bubalus trutralisl, pigs (Sus scrofal, all of which have been introduced. The dingo ICanis familiaris dingo/, classified as being a native species by most people, is the primary native animal causing problems, although others, such as kangaroos and several native bird species, are pests in some areas. The Australians spend considerable amounts of money on wildlife damage control research. The people of Western Australia take a regulatory approach to most of their wildlife problems. The concept of declaring species as pests allows the Australians to regulate what can and should be done to control these species. Australian wildlife control programs range from conducting control activities to simply advising as to what should be done. The Australians often designate areas where control should (or should not) be undertaken. This approach allows clear decisions to be made about control program expenditures and resource deployment

Differential effects of Alzheimer\u27s disease and Huntington\u27s disease on the performance of mental rotation

he ability to spatially rotate a mental image was compared in patients with Alzheimer\u27s disease (AD; n = 18) and patients with Huntington\u27s disease (HD; n = 18). Compared to their respective age-matched normal control (NC) group, the speed, but not the accuracy, of mental rotation abnormally decreased with increasing angle of orientation for patients with HD. In contrast, the accuracy, but not the speed, of rotation abnormally decreased with increasing angle of orientation for patients with AD. Additional analyses showed that these unique patterns of performance were not attributable to different speed/accuracy trade-off sensitivities. This double dissociation suggests that the distinct brain regions affected in the two diseases differentially contribute to speed and accuracy of mental rotation. Specifically, the slowing exhibited by HD patients may be mediated by damage to the basal ganglia, whereas the spatial manipulation deficit of AD patients may reflect pathology in parietal and temporal lobe association cortices important for visuospatial processing. (JINS, 2005, 11, 30–39.

A randomized controlled trial of PEEK versus titanium interference screws for anterior cruciate ligament reconstruction with 2-year follow-up

Purpose: To compare the clinical performance of ACL reconstruction with PEEK and titanium interference screws at 2 years and to evaluate a novel method of measuring tunnel volume. Study Design: Randomized controlled trial; Level of evidence, 1. Methods: A total of 133 patients underwent arthroscopic ACL reconstruction with 4-strand hamstring autografts and were randomized to have titanium or PEEK interference screws for femoral and tibial tunnel fixation. At 2 years, subjective Lysholm and International Knee Documentation Committee scores were assessed and clinical examination performed. At 12 months, MRI was performed to assess graft incorporation and cyst formation, and a novel technique was employed to measure tunnel volumes. Results: There were no significant differences in graft rerupture rate, contralateral ACL rupture rate, subjective outcomes, or objective outcomes. In the titanium and PEEK groups, MRI demonstrated high overall rates of graft integration (96%-100% and 90%-93%, respectively) and ligamentization (89% and 84%) and low rates of synovitis (22% and 10%) and cyst formation (0%-18% and 13%-15%). There was a higher proportion of patients with incomplete graft integration within the femoral tunnel in the PEEK group as compared with the titanium group (10% vs 0%, P = .03); however, the authors suggest that metal artifact precluded proper assessment of the graft in the titanium group by MRI. Tunnel volumes also appeared to be equivalent in the 2 groups and were measured with a novel technique that was highly reproducible in the PEEK group secondary to the absence of flare. Conclusion: Two-year clinical analysis of PEEK interference screws for femoral and tibial fixation of ACL reconstructions showed equivalent clinical performance to titanium interference screws. Given the excellent mechanical characteristics, biological compatibility, and absence of metal artifact on MRI, PEEK has become our material of choice for interference screw fixation in ACL reconstruction

Slow flows of an relativistic perfect fluid in a static gravitational field

Relativistic hydrodynamics of an isentropic fluid in a gravitational field is considered as the particular example from the family of Lagrangian hydrodynamic-type systems which possess an infinite set of integrals of motion due to the symmetry of Lagrangian with respect to relabeling of fluid particle labels. Flows with fixed topology of the vorticity are investigated in quasi-static regime, when deviations of the space-time metric and the density of fluid from the corresponding equilibrium configuration are negligibly small. On the base of the variational principle for frozen-in vortex lines dynamics, the equation of motion for a thin relativistic vortex filament is derived in the local induction approximation.Comment: 4 pages, revtex, no figur

Speech of Hon. Salmon P. Chase.

Speech of Honorary Salmon P. Chase delivered at the Republican Mass Meeting in Cincinnati, August 21, 1855. Together with extracts from his speeches in the Senate of Kindred subjects. Consisting of 16 pages.https://stars.library.ucf.edu/civilwar-text/1023/thumbnail.jp

Letter, Salmon P. Chase to Elliot C. Cowden, September 2, 1862

This handwritten letter, dated September 8, 1862, is from Salmon P. Chase to Elliot C. Cowden as a response to Cowden\u27s letter to Chase on September 2. Chase informs Cowden that Mr. John Mack\u27s appointment was made by the President on the recommendation of some of the best the citizens of New York and is not under the purview of the Secretary of the Treasury. Chase goes on to encourage that perhaps experience will prove the selection not so injudicious as you think it now. A Treasury Department envelope postmarked Washington, D. C. Sep. 9, 1862 and addressed to Elliot C. Cowdin, Esq. in New York is included with the letter.https://scholarsjunction.msstate.edu/fvw-manuscripts-original-manuscripts/1130/thumbnail.jp