SCADA System Testbed for Cybersecurity Research Using Machine Learning Approach

This paper presents the development of a Supervisory Control and Data Acquisition (SCADA) system testbed used for cybersecurity research. The testbed consists of a water storage tank's control system, which is a stage in the process of water treatment and distribution. Sophisticated cyber-attacks were conducted against the testbed. During the attacks, the network traffic was captured, and features were extracted from the traffic to build a dataset for training and testing different machine learning algorithms. Five traditional machine learning algorithms were trained to detect the attacks: Random Forest, Decision Tree, Logistic Regression, Naive Bayes and KNN. Then, the trained machine learning models were built and deployed in the network, where new tests were made using online network traffic. The performance obtained during the training and testing of the machine learning models was compared to the performance obtained during the online deployment of these models in the network. The results show the efficiency of the machine learning models in detecting the attacks in real time. The testbed provides a good understanding of the effects and consequences of attacks on real SCADA environmentsComment: E-Preprin

High Resolution Surface Reconstruction from Overlapping Multiple-Views

International audienceExtracting a computer model of a real scene from a sequence of views, is one of the most challenging and fundamental problems in computer vision. Stereo vision algorithms allow us to extract from the images a sparse 3D point cloud on the scene surfaces. However, computing an accurate mesh of the scene based on such poor quality data points (noise, sparsity) is very difficult. Here we describe a simple yet original approach that uses both the stereo vision extracted point cloud and the calibrated images. Our method is a three-stage process in which the first stage merges, filters and smoothes the input 3D points. The second stage builds for each calibrated image a triangular depth-map and fuses the set of depth-maps into a triangle soup that minimize violations of size and visibility constraints. Finally, a mesh is computed from the triangle soup using a reconstruction method that combines restricted Delaunay triangulation and Delaunay refinement

Feature Preserving Mesh Generation from 3D Point Clouds

Special issue for EUROGRAPHICS Symposium on Geometry Processing, Lyon 2010International audienceWe address the problem of generating quality surface triangle meshes from 3D point clouds sampled on piecewise smooth surfaces. Using a feature detection process based on the covariance matrices of Voronoi cells, we first ex- tract from the point cloud a set of sharp features. Our algorithm also runs on the input point cloud a reconstruction process, such as Poisson reconstruction, providing an implicit surface. A feature preserving variant of a Delaunay refinement process is then used to generate a mesh approximating the implicit surface and containing a faithful representation of the extracted sharp edges. Such a mesh provides an enhanced trade-off between accuracy and mesh complexity. The whole process is robust to noise and made versatile through a small set of parameters which govern the mesh sizing, approximation error and shape of the elements. We demonstrate the effectiveness of our method on a variety of models including laser scanned datasets ranging from indoor to outdoor scenes

Formalization of the neuro-biological models for spike neurons.

When modelizing cortical neuronal maps (here spiking neuronal networks) within the scope of the FACETS project, researchers in neuro-science and computer-science use NeuroML, a XML language, to specify biological neuronal networks. These networks could be simulated either using analogue or event-based techniques. Specifications include : - parametric model specification - model equation symbolic definition - formalization of related semantic aspects (paradigms, ..) and they are used by "non-computer-scientists". In this context XML is used to specify data structures, not documents. The first version of NeuroML uses Java to map XML biological data which can be later simulated within GENESIS, NEURON, etc. The second version uses tools for handling XML data, as XSL, to transform an XML file. To allow NeuroML to be used intensively within the scope of the FACETS project, we will entirely analyse the software. First we are going to evaluate this software deeply in the Technical Report section. Then we will propose a prototype to write down NeuroML code easily

Cage Culture in Iraq, Current Status & Potential: A Review

The present investigation aimed at discussing the present status of cage culture in Iraq and its future potential. Iraqi water resources can provide the basic requirements for successful fish culture in cages. Environmental conditions may maintain sustainable growth rate for 10 months at least. This has encouraged the investors and fish culturists to adopt such technique and make use of its advantages. Development of cage culture in Iraq has been reviewed from the early seventies till now. Fish production from cage culture was analyzed focusing upon recent developments in terms of fish consumption criteria and the per capita in Iraq. The floating cages culture system is considered now as the main culture system, because environmental conditions are suitable for cage culture more than the earthen ponds and recirculating systems. Cage culture industry relies on row materials that are locally available. They includes, frames, bridges, passage ways, nets, floating materials, feeders and wave breakers. Most of the cage units are locally manufactured from steel or wooden frame in square or rectangular shapes. Some circular and octahedral units are used in Kurdistan and Mosul. Researches on cage culture continued to optimize parameters such as stocking density, feeding and stocking sizes, stocking density of fish in the cages was fixed at 60-70 fish per m3 or 1500-2000 fish per cage of 1.5 x 4 x 4m using fish of 100 g in weight. Problems facing cage culture in Iraq are summarized by high prices of feeds, viral infection and other fish diseases, deterioration of water quality, the policy of importing fish from neighboring countries and lack of skills among farmers. Solutions for the above problems and recommendations for future development are discussed at the end of the article

Cage Culture in Iraq, Current Status & Potential: A Review

The present investigation aimed at discussing the present status of cage culture in Iraq and its future potential. Iraqi water resources can provide the basic requirements for successful fish culture in cages. Environmental conditions may maintain sustainable growth rate for 10 months at least. This has encouraged the investors and fish culturists to adopt such technique and make use of its advantages. Development of cage culture in Iraq has been reviewed from the early seventies till now. Fish production from cage culture was analyzed focusing upon recent developments in terms of fish consumption criteria and the per capita in Iraq. The floating cages culture system is considered now as the main culture system, because environmental conditions are suitable for cage culture more than the earthen ponds and recirculating systems. Cage culture industry relies on row materials that are locally available. They includes, frames, bridges, passage ways, nets, floating materials, feeders and wave breakers. Most of the cage units are locally manufactured from steel or wooden frame in square or rectangular shapes. Some circular and octahedral units are used in Kurdistan and Mosul. Researches on cage culture continued to optimize parameters such as stocking density, feeding and stocking sizes, stocking density of fish in the cages was fixed at 60-70 fish per m3 or 1500-2000 fish per cage of 1.5 x 4 x 4m using fish of 100 g in weight. Problems facing cage culture in Iraq are summarized by high prices of feeds, viral infection and other fish diseases, deterioration of water quality, the policy of importing fish from neighboring countries and lack of skills among farmers. Solutions for the above problems and recommendations for future development are discussed at the end of the article

Methods and matrices: Approaches to identifying miRNAs for nasopharyngeal carcinoma

We tested two miRNA discovery workflows on two sample sources for miRNAs associated with NPC. In the first workflow, we assumed that NPC tumor tissue would be enriched for miRNAs, so we compared miRNA expression in FFPE from NPC cases and controls using microarray and RNA-Seq technologies. Candidate miRNAs from both technologies were verified by qPCR in FFPE and sera from an independent NPC sample set. In a second workflow, we directly interrogated NPC case and control sera by RNA-Seq for c-miRNAs associated with NPC, with candidate c-miRNAs verified by qPCR in the sera from the same independent NPC sample set. Results Both microarray and RNA-Seq narrowed the miRNA signature to 1-5% of the known mature human miRNAs. Moreover, these two methods produced similar results when applied to the same sample type (FFPE), with RNA-Seq additionally indicating “unknown” miRNAs associated with NPC. However, we found different miRNA profiles in NPC sera compared to FFPE using RNA-Seq, with the few overlapping miRNAs found to be significantly up-regulated in FFPE significantly down-regulated in sera (and vice versa). Despite the different miRNA profiles found in FFPE and sera, both profiles strongly associated with NPC, providing two potential sources for biomarker signatures for NPC. Conclusions We determined that the direct interrogation of sera by RNA-Seq was the most informative method for identifying a c-miRNA signature associated with NPC. We also showed that there are different miRNA expression profiles associated with NPC for tumor tissue and sera. These results reflect on the methods and meaning of miRNA biomarkers for NPC in tissue and peripheral blood

Digitising diabetes education for a safer Ramadan:Design, delivery, and evaluation of massive open online courses in Ramadan-focused diabetes education

AIMS: Ramadan-focused diabetes education is critical to facilitate safer Ramadan fasting amongst Muslim people living with diabetes. We present the design, delivery, and evaluation of two parallel massive open online courses (MOOCs) in Ramadan-focused diabetes education for people with diabetes and HCPs.METHODS: Two Ramadan-focused diabetes education MOOCs were developed and delivered for Ramadan 2023: one for HCPs in English, and another for people with diabetes in English, Arabic and Malay. A user-centred iterative design process was adopted, informed by user feedback from a 2022 pilot MOOC. Evaluation comprised a mixed-methods evaluation of pre- and post-course user surveys.RESULTS: The platform was utilised by people with diabetes and their family, friends and healthcare professionals. Overall, a total of 1531 users registered for the platform from 50 countries, 809 started a course with a 48% subsequent completion rate among course starters. Qualitative analysis showed users found the course a user-friendly and authoritative information source. In the HCP MOOC, users reported improved post-MOOC Ramadan awareness, associated diabetes knowledge and ability to assess and advise patients in relation to their diabetes during Ramadan (p&lt;0.01).CONCLUSIONS: We demonstrate the potential of MOOCs to deliver culturally tailored, high-quality, scalable, multilingual Ramadan-focused diabetes education to HCPs and people with diabetes.</p

Global, regional, and national burden of chronic kidney disease, 1990–2017 : a systematic analysis for the Global Burden of Disease Study 2017

Background Health system planning requires careful assessment of chronic kidney disease (CKD) epidemiology, but data for morbidity and mortality of this disease are scarce or non-existent in many countries. We estimated the global, regional, and national burden of CKD, as well as the burden of cardiovascular disease and gout attributable to impaired kidney function, for the Global Burden of Diseases, Injuries, and Risk Factors Study 2017. We use the term CKD to refer to the morbidity and mortality that can be directly attributed to all stages of CKD, and we use the term impaired kidney function to refer to the additional risk of CKD from cardiovascular disease and gout. Methods The main data sources we used were published literature, vital registration systems, end-stage kidney disease registries, and household surveys. Estimates of CKD burden were produced using a Cause of Death Ensemble model and a Bayesian meta-regression analytical tool, and included incidence, prevalence, years lived with disability, mortality, years of life lost, and disability-adjusted life-years (DALYs). A comparative risk assessment approach was used to estimate the proportion of cardiovascular diseases and gout burden attributable to impaired kidney function. Findings Globally, in 2017, 1·2 million (95% uncertainty interval [UI] 1·2 to 1·3) people died from CKD. The global all-age mortality rate from CKD increased 41·5% (95% UI 35·2 to 46·5) between 1990 and 2017, although there was no significant change in the age-standardised mortality rate (2·8%, −1·5 to 6·3). In 2017, 697·5 million (95% UI 649·2 to 752·0) cases of all-stage CKD were recorded, for a global prevalence of 9·1% (8·5 to 9·8). The global all-age prevalence of CKD increased 29·3% (95% UI 26·4 to 32·6) since 1990, whereas the age-standardised prevalence remained stable (1·2%, −1·1 to 3·5). CKD resulted in 35·8 million (95% UI 33·7 to 38·0) DALYs in 2017, with diabetic nephropathy accounting for almost a third of DALYs. Most of the burden of CKD was concentrated in the three lowest quintiles of Socio-demographic Index (SDI). In several regions, particularly Oceania, sub-Saharan Africa, and Latin America, the burden of CKD was much higher than expected for the level of development, whereas the disease burden in western, eastern, and central sub-Saharan Africa, east Asia, south Asia, central and eastern Europe, Australasia, and western Europe was lower than expected. 1·4 million (95% UI 1·2 to 1·6) cardiovascular disease-related deaths and 25·3 million (22·2 to 28·9) cardiovascular disease DALYs were attributable to impaired kidney function. Interpretation Kidney disease has a major effect on global health, both as a direct cause of global morbidity and mortality and as an important risk factor for cardiovascular disease. CKD is largely preventable and treatable and deserves greater attention in global health policy decision making, particularly in locations with low and middle SDI

The global, regional, and national burden of cirrhosis by cause in 195 countries and territories, 1990-2017 : a systematic analysis for the Global Burden of Disease Study 2017

Background Cirrhosis and other chronic liver diseases (collectively referred to as cirrhosis in this paper) are a major cause of morbidity and mortality globally, although the burden and underlying causes differ across locations and demographic groups. We report on results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 on the burden of cirrhosis and its trends since 1990, by cause, sex, and age, for 195 countries and territories. Methods We used data from vital registrations, vital registration samples, and verbal autopsies to estimate mortality. We modelled prevalence of total, compensated, and decompensated cirrhosis on the basis of hospital and claims data. Disability-adjusted life-years (DALYs) were calculated as the sum of years of life lost due to premature death and years lived with disability. Estimates are presented as numbers and age-standardised or age-specific rates per 100 000 population, with 95% uncertainty intervals (UIs). All estimates are presented for five causes of cirrhosis: hepatitis B, hepatitis C, alcohol-related liver disease, non-alcoholic steatohepatitis (NASH), and other causes. We compared mortality, prevalence, and DALY estimates with those expected according to the Socio-demographic Index (SDI) as a proxy for the development status of regions and countries. Findings In 2017, cirrhosis caused more than 1.32 million (95% UI 1.27-1.45) deaths (440000 [416 000-518 000; 33.3%] in females and 883 000 [838 000-967 000; 66.7%] in males) globally, compared with less than 899 000 (829 000-948 000) deaths in 1990. Deaths due to cirrhosis constituted 2.4% (2.3-2.6) of total deaths globally in 2017 compared with 1.9% (1.8-2.0) in 1990. Despite an increase in the number of deaths, the age-standardised death rate decreased from 21.0 (19.2-22.3) per 100 000 population in 1990 to 16.5 (15.8-18-1) per 100 000 population in 2017. Sub-Saharan Africa had the highest age-standardised death rate among GBD super-regions for all years of the study period (32.2 [25.8-38.6] deaths per 100 000 population in 2017), and the high-income super-region had the lowest (10.1 [9.8-10-5] deaths per 100 000 population in 2017). The age-standardised death rate decreased or remained constant from 1990 to 2017 in all GBD regions except eastern Europe and central Asia, where the age-standardised death rate increased, primarily due to increases in alcohol-related liver disease prevalence. At the national level, the age-standardised death rate of cirrhosis was lowest in Singapore in 2017 (3.7 [3.3-4.0] per 100 000 in 2017) and highest in Egypt in all years since 1990 (103.3 [64.4-133.4] per 100 000 in 2017). There were 10.6 million (10.3-10.9) prevalent cases of decompensated cirrhosis and 112 million (107-119) prevalent cases of compensated cirrhosis globally in 2017. There was a significant increase in age-standardised prevalence rate of decompensated cirrhosis between 1990 and 2017. Cirrhosis caused by NASH had a steady age-standardised death rate throughout the study period, whereas the other four causes showed declines in age-standardised death rate. The age-standardised prevalence of compensated and decompensated cirrhosis due to NASH increased more than for any other cause of cirrhosis (by 33.2% for compensated cirrhosis and 54.8% for decompensated cirrhosis) over the study period. From 1990 to 2017, the number of prevalent cases snore than doubled for compensated cirrhosis due to NASH and more than tripled for decompensated cirrhosis due to NASH. In 2017, age-standardised death and DALY rates were lower among countries and territories with higher SDI. Interpretation Cirrhosis imposes a substantial health burden on many countries and this burden has increased at the global level since 1990, partly due to population growth and ageing. Although the age-standardised death and DALY rates of cirrhosis decreased from 1990 to 2017, numbers of deaths and DALYs and the proportion of all global deaths due to cirrhosis increased. Despite the availability of effective interventions for the prevention and treatment of hepatitis B and C, they were still the main causes of cirrhosis burden worldwide, particularly in low-income countries. The impact of hepatitis B and C is expected to be attenuated and overtaken by that of NASH in the near future. Cost-effective interventions are required to continue the prevention and treatment of viral hepatitis, and to achieve early diagnosis and prevention of cirrhosis due to alcohol-related liver disease and NASH. Copyright (C) 2020 The Author(s). Published by Elsevier Ltd.Peer reviewe