988 research outputs found

    On the Z_p-ranks of tamely ramified Iwasawa modules

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    For a prime number p, we denote by K the cyclotomic Z_p-extension of a number field k. For a finite set S of prime numbers, we consider the S-ramified Iwasawa module which is the Galois group of the maximal abelian pro-p-extension of K unramified outside S. This paper treats the case where S does not contain p and k is the rational number field or an imaginary quadratic field. In this case, we prove the explicit formulae for the free ranks of the S-ramified Iwasawa modules as abelian pro-p groups, by using Brumer's p-adic version of Baker's theorem on the linear independence of logarithms of algebraic numbers

    Renormalised nonequilibrium quantum field theory: scalar fields

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    We discuss the renormalisation of the initial value problem in quantum field theory using the two-particle irreducible (2PI) effective action formalism. The nonequilibrium dynamics is renormalised by counterterms determined in equilibrium. We emphasize the importance of the appropriate choice of initial conditions and go beyond the Gaussian initial density operator by defining self-consistent initial conditions. We study the corresponding time evolution and present a numerical example which supports the existence of a continuum limit for this type of initial conditions.Comment: 18 pages in revtex4, 5 figure

    Alien Registration- De Salle, Maria L. (Rumford, Oxford County)

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    https://digitalmaine.com/alien_docs/12683/thumbnail.jp

    Lyapunov Control on Quantum Open System in Decoherence-free Subspaces

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    A scheme to drive and manipulate a finite-dimensional quantum system in the decoherence-free subspaces(DFS) by Lyapunov control is proposed. Control fields are established by Lyapunov function. This proposal can drive the open quantum system into the DFS and manipulate it to any desired eigenstate of the free Hamiltonian. An example which consists of a four-level system with three long-lived states driven by two lasers is presented to exemplify the scheme. We have performed numerical simulations for the dynamics of the four-level system, which show that the scheme works good.Comment: 5 pages, 6 figure

    Diosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpression

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    In the present study, we have shown for the first time that a plant steroid, diosgenin, causes an inhibition of the growth of fibroblast-like synoviocytes from human rheumatoid arthritis, with apoptosis induction associated with cyclooxygenase-2 (COX-2) up-regulation. Celecoxib, a selective COX-2 inhibitor, provoked a large decrease in diosgenin-induced apoptosis even in the presence of exogenous prostaglandin E(2), whereas interleukin-1β, a COX-2 inducer, strongly increased diosgenin-induced apoptosis of these synoviocytes. These findings suggest that the proapoptotic effect of diosgenin is associated with overexpression of COX-2 correlated with overproduction of endogenous prostaglandin E(2). We also observed a loss of mitochondrial membrane potential, caspase-3 activation, and DNA fragmentation after diosgenin treatment

    Discurso do orador da turma de bacharelandos de 1938

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    pATsi: Paralogs and singleton genes from Arabidopsis thaliana

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    Arabidopsis thaliana is widely accepted as a model species in plant biology. Its genome, due to its small size and diploidy, was the first to be sequenced among plants, making this species also a reference for plant comparative genomics. Nevertheless, the evolutionary mechanisms that shaped the Arabidopsis genome are still controversial. Indeed, duplications, translocations, inversions, and gene loss events that contributed to the current organization are difficult to be traced. A reliable identification of paralogs and single-copy genes is essential to understand these mechanisms. Therefore, we implemented a dedicated pipeline to identify paralog genes and classify single-copy genes into opportune categories. PATsi, a web-accessible database, was organized to allow the straightforward access to the paralogs organized into networks and to the classification of single-copy genes. This permits to efficiently explore the gene collection of Arabidopsis for evolutionary investigations and comparative genomics

    Post-transplant cerebral toxoplasmosis diagnosed by magnetic resonance imaging.

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    Cerebral toxoplasmosis is a rare late complication in allogeneic bone marrow transplanted patients. Neuroradiological findings may suggest the correct diagnosis. We report a patient in whom cerebral magnetic resonance imaging (MRI) showed a lesion characteristic of toxoplasmosis. Anti- toxoplasma treatment led to clinical and radiological improvement. MRI seems to be a valid tool for detection and follow-up of cerebral toxoplasmosis

    An Assessment of Risk of Iodine Deficiency Among Pregnant Women in Sarawak, Malaysia

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    Previous findings from a state-wide Iodine Deficiency Disorders (IDD) study among pregnant women (PW) in Sarawak indicated that PW are at risk of IDD and further assessment is needed. This paper describes the methodology used in conducting this study for an assessment of risk of iodine deficiency among pregnant women in Sarawak, Malaysia. A total of 30 maternal child health care clinics (MCHCs) were selected using probability proportional to population size (PPS) sampling technique. The PW sample size was calculated based on 95% confidence interval (CI), relative precision of 5%, design effect of 2, anticipated IDD prevalence of 65.0% and non-response rate of 20%. Thus, the total sample size required was 750 (25 respondents per selected MCHC). The WHO Expanded Programme on Immunization (EPI) surveys approach was used to randomly select the first respondent and subsequent respondents were chosen until the required number of PW was met. The required data were obtained through: face-to-face interviews (socio-demographic and food frequency questionnaire), clinical assessments (thyroid size, and hyper/hypothyroidism) and biochemical analysis (urine and blood serum). A total of 677 PW responded in the study with a response rate of 90.2%. Majority of the PW were at second gravida, aged 25-29 years old and of Malay ethnicity. The methodology used in this study was based on International guidelines which may provide state's estimates. All the necessary steps were taken into consideration to ensure valid and reliable findings on current iodine status among PW

    Long-Term Fluoride Release from Dental Resins Affects STRO-1+ Cell Behavior.

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    Fluoride-releasing restorative dental materials can be beneficial to remineralize dentin and help prevent secondary caries. However, the effects of fluoride release from dental materials on the activity of dental pulp stem cells are not known. Here we investigate whether different fluoride release kinetics from dental resins supplemented with modified hydrotalcite (RK-F10) or fluoride-glass filler (RK-FG10) could influence the behavior of a human dental pulp stem cell subpopulation (STRO-1(+) cells) known for its ability to differentiate toward an odontoblast-like phenotype. The 2 resins, characterized by similar physicochemical properties and fluoride content, exhibited different long-term fluoride release kinetics. Our data demonstrate that long-term exposure of STRO-1(+) cells to a continuous release of a low amount of fluoride by RK-F10 increases their migratory response to transforming growth factor β1 (TGF-β1) and stromal cell-derived factor 1 (SDF-1), both important promoters of pulp stem cell recruitment. Moreover, the expression patterns of dentin sialoprotein (dspp), dentin matrix protein 1 (dmp1), osteocalcin (ocn), and matrix extracellular phosphoglycoprotein (mepe) indicate a complete odontoblast-like cell differentiation only when STRO-1(+) cells were cultured on RK-F10. On the contrary, RK-FG10, characterized by an initial fluoride release burst and reduced lifetime of the delivery, did not elicit any significant effect on both STRO-1(+) cell migration and differentiation. Taken together, our results highlight the importance of taking into account fluoride release kinetics in addition to fluoride concentration when designing new fluoride-restorative materials
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