Big differences in primary care celiac disease serological markers request in Spain

Introduction: Celiac disease (CD) prevalence is increasing but the disorder remains undiagnosed. The study compares CD serology markers requested by General Practitioners (GPs) over time and geographical areas. The aim of the current research is to assess the inter-practice and temporal variability in the request of CD serology markers by GPs in Spain, and the differences between regions. Materials and methods: A cross-sectional study was conducted enrolling Spanish clinical laboratories. Primary care CD serology markers request in 2010, 2012 and 2014 from 15 autonomous communities (AACC), with more participants was reported. Test-utilization rates were calculated (tissue transglutaminase IgA antibodies (tTG-IgA) and deaminated peptide gliadine IgA antibodies (DGP-IgA) per 1000 inhabitants), and also the ratio of both tests request (DGP-IgA /tTG-IgA). Results: The request of tTG-IgA per 1000 inhabitants increased significantly along years (from 3.99 to 5.90 (P < 0.001)). The demand of DGP-IgA per 1000 inhabitants was maintained in 2010 and 2012 (0.68 and 0.6), and decreased in 2014 (0.35) (P = 0.927). DGP-IgA /tTG-IgA diminished over time (from 0.16 to 0.06 (P = 0.548)), and in the 2014 edition, there was a significant regional difference, ranging from 0.01 to 0.57 (P < 0.001). Conclusions: The variability in the request in CD serology markers emphasizes the need of inter-regional cooperation to develop strategies to optimize the use of laboratory test

Agile in Public Administration: Oxymoron or reality? An experience report

In the last 10 years, Agile methods and practices have emerged as an alternative for software development. Different "flavors" of Agile have appeared ranging from project management to tests organization. These approaches have being gaining popularity and involve now a solid option for organizations developing software, but what about Public Administrations? Is Agile a suitable option for developing software in Public Administrations? Even if Public Administrations have been traditionally regarded as changeresistant, Agile approach can also provide them with the benefits of quick adaptation and frequent value delivery. This paper presents the results of two different projects, which use an Agile framework based on Scrum, developed by a Spanish Public Administration. Additionally, after considering the obtained results, it takes out some relevant learned lessons on the suitability of applying Agile approaches to Public Administration environments.Ministerio de Ciencia e Innovación TIN2010-20057-C03-02Junta de Andalucía TIC-578

An Approach to Transform Public Administration into SOA-based Organizations

Nowadays, Service-Oriented Architectures (SOA) is widely spread in private organizations. However, when transferring this knowledge to Public Administration, it is realized that it has not been transformed in terms of its legal nature into organizations capable to operate under the SOA paradigm. This fact prevents public administration bodies from offering the efficient services they have been provided by different boards of governments. A high-level framework to perform this transformation is proposed. Taking it as starting point, an instance of a SOA Target Meta-Model can be obtained by means of an iterative and incremental process based on the analysis of imperatives and focused on the particular business context of each local public administration. This paper briefly presents a practical experience consisting in applying this process to a Spanish regional public administration.Junta de Andalucía TIC-578

Agile, Web Engineering and Capability Maturity ModelI ntegration : A systematic literature review

Context Agile approaches are an alternative for organizations developing software, particularly for those who develop Web applications. Besides, CMMI (Capability Maturity Model Integration) models are well-established approaches focused on assessing the maturity of an organization that develops software. Web Engineering is the field of Software Engineering responsible for analyzing and studying the specific characteristics of the Web. The suitability of an Agile approach to help organizations reach a certain CMMI maturity level in Web environments will be very interesting, as they will be able to keep the ability to quickly react and adapt to changes as long as their development processes get mature. Objective This paper responds to whether it is feasible or not, for an organization developing Web systems, to achieve a certain maturity level of the CMMI-DEV model using Agile methods. Method The proposal is analyzed by means of a systematic literature review of the relevant approaches in the field, defining a characterization schema in order to compare them to introduce the current state-of-the-art. Results The results achieved after the systematic literature review are presented, analyzed and compared against the defined schema, extracting relevant conclusions for the different dimensions of the problem: compatibility, compliance, experience, maturity and Web. Conclusion It is concluded that although the definition of an Agile approach to meet the different CMMI maturity levels goals could be possible for an organization developing Web systems, there is still a lack of detailed studies and analysis on the field

Estimating, planning and managing Agile Web development projects under a value-based perspective

Context: The processes of estimating, planning and managing are crucial for software development projects, since the results must be related to several business strategies. The broad expansion of the Internet and the global and interconnected economy make Web development projects be often characterized by expressions like delivering as soon as possible, reducing time to market and adapting to undefined requirements. In this kind of environment, traditional methodologies based on predictive techniques sometimes do not offer very satisfactory results. The rise of Agile methodologies and practices has provided some useful tools that, combined with Web Engineering techniques, can help to establish a framework to estimate, manage and plan Web development projects. Objective: This paper presents a proposal for estimating, planning and managing Web projects, by combining some existing Agile techniques with Web Engineering principles, presenting them as an unified framework which uses the business value to guide the delivery of features. Method: The proposal is analyzed by means of a case study, including a real-life project, in order to obtain relevant conclusions. Results: The results achieved after using the framework in a development project are presented, including interesting results on project planning and estimation, as well as on team productivity throughout the project. Conclusion: It is concluded that the framework can be useful in order to better manage Web-based projects, through a continuous value-based estimation and management process.Ministerio de Economía y Competitividad TIN2013-46928-C3-3-

Additional technician tasks and turnaround time in the clinical Stat laboratory.

Introduction: Many additional tasks in the Stat laboratory (SL) increase the workload. It is necessary to control them because they can affect the service provided by the laboratory. Our aim is to calculate these tasks, study their evolution over a 10 year period, and compare turnaround times (TAT) in summer period to the rest of the year. Materials and methods: Additional tasks were classified as “additional test request” and “additional sample”. We collected those incidences from the laboratory information system (LIS), and calculated their evolution over time. We also calculated the monthly TAT for troponin for Emergency department (ED) patients, as the difference between the verification and LIS registration time. A median time of 30 minutes was our indicator target. TAT results and tests workload in summer were compared to the rest of the year. Results: Over a 10-year period, the technologists in the SL performed 51,385 additional tasks, a median of 475 per month. The workload was significantly higher during the summer (45,496 tests) than the rest of the year (44,555 tests) (P = 0.019). The troponin TAT did not show this variation between summer and the rest of the year, complying always with our 30 minutes indicator target. Conclusion: The technicians accomplished a significant number of additional tasks, and the workload kept increasing over the period of 10 years. That did not affect the TAT results

El fraude en la ciencia: reflexiones a partir del caso Hwang

In 2006 Hwang's fraudulent papers published in Science on stem cell research re-opened the debate on scientific misconduct. Taking this as a starting point, some reflections are put forward on the dimension of fraud in science. The singularity of Hwang's case, due to its scientific, social and media impact, is examined as a consequence of the persuasion mechanisms systematised in the so-called Routes of Scholarly Lying. Furthermore, the reasons for publishing fraudulent research, the inefficiency of peer review for detecting it, and the various mechanisms for managing and eradicating it, are presented