Relationship between obesity, ethnicity and risk of late stillbirth: a case control study

<p>Abstract</p> <p>Background</p> <p>In high income countries there has been little improvement in stillbirth rates over the past two decades. Previous studies have indicated an ethnic disparity in the rate of stillbirths. This study aimed to determine whether maternal ethnicity is independently associated with late stillbirth in New Zealand.</p> <p>Methods</p> <p>Cases were women with a singleton, late stillbirth (≥28 weeks' gestation) without congenital abnormality, born between July 2006 and June 2009 in Auckland, New Zealand. Two controls with ongoing pregnancies were randomly selected at the same gestation at which the stillbirth occurred. Women were interviewed in the first few weeks following stillbirth, or at the equivalent gestation for controls. Detailed demographic data were recorded. The study was powered to detect an odds ratio of 2, with a power of 80% at the 5% level of significance, given a prevalence of the risk factor of 20%. A multivariable regression model was developed which adjusted for known risk factors for stillbirth, as well as significant risk factors identified in the current study, and adjusted odds ratios and 95% confidence intervals were calculated.</p> <p>Results</p> <p>155/215 (72%) cases and 310/429 (72%) controls consented. Pacific ethnicity, overweight and obesity, grandmultiparity, not being married, not being in paid work, social deprivation, exposure to tobacco smoke and use of recreational drugs were associated with an increased risk of late stillbirth in univariable analysis. Maternal overweight and obesity, nulliparity, grandmultiparity, not being married and not being in paid work were independently associated with late stillbirth in multivariable analysis, whereas Pacific ethnicity was no longer significant (adjusted Odds Ratio 0.99; 0.51-1.91).</p> <p>Conclusions</p> <p>Pacific ethnicity was not found to be an independent risk factor for late stillbirth in this New Zealand study. The disparity in stillbirth rates between Pacific and European women can be attributed to confounding factors such as maternal obesity and high parity.</p

Network layer for cognitive radio sensor networks

Based on recent trends, Cognitive Radio paradigm has become an integral part of future communication networks of which Wireless Sensor Network is an integral part. However, Cognitive Radio (CR) introduces critical issues that have to be addressed for communication in networks to be achieved. Routing, being the core of communication, has to be critically examined within the context of Cognitive Radio Sensor Networks. In this chapter, the authors discuss relevant issues on the topic of routing in Cognitive Radio Sensor Networks (CRSN). As a basis, a general overview of routing in the Wireless Sensor Network (WSN) is made. The applicability of these protocols in CRSN is discussed and the need for integrating Opportunistic Spectrum Access components into existing Wireless Sensor Network protocols is exposed. Factors affecting routing in CRSN are outlined with an emphasis on a cross layering design approach based on a generalized framework. Recent works in this respect are categorized, and finally, open issues in need for research attention are pinpointed

Disinfectant effect of Methylated Ethanol against Listeria species 1

This study was carried out in order to determine the disinfectant effect of Methylated spirit ® (95% methanol and 5 % ethanol) as a teat dip against Listeria species. Hand milking was employed to collect 576 (288 x 2) raw milk samples from different lactating cows within Sokoto metropolis (Nigeria). 288 samples were collected before disinfecting the udder teats with Methylated spirit®, while the other 288 were collected after disinfection with Methylated spirit®. The samples were analyzed using selective culture and isolation technique in which the 288 samples collected before disinfection, 114 (39.6%) were positive for Listeria species. Among the positive samples 44 (38.6%) were Listeria innocua, 16 (14.0%) Listeria ivanovii, 36 (31.6%) Listeria monocytogenes, 11 (9.6%) Listeria welshimeri and 7 (6.1%) Listeria seeligeri, while none of the 288 samples collected after disinfection was positive. The study has shown high prevalence of Listeria species in milk collected without washing/disinfecting the teats and has also established the sensitivity of Listeria species to methylated ethanol which can be used as dip for disinfecting udder teats before milking in order to prevent contamination with Listeria species and other methylated spirit-sensitive organisms. This study is essential to educate Fulani herdsmen and other milk handlers on the importance of disinfecting udder teats before milking

Mosquito-larvicidal efficacy of the extract of Musca domestica maggots against Culex pipiens (Diptera: culidae), an important vector of Filariasis

The intolerably high burdens of mosquito-borne diseases will be reduced sustainably through the development of integral eco-friendly alternative insecticides of natural products origin. The need to broaden the global search for such insecticidal lead-agents, especially , those that will be less vulnerable to resistance, was the reason why this bio-assay study was carried out to test Musca domestica maggots against 4th instar larvae of the mosquito Culex pipiens pipiens. The larvicidal bio-assay followed standard World Health Organisation‟s protocols for testing the susceptibility of mosquitoes to larvicides. Larvicidal tests were carried out in a series of extract concentrations ranging from 0.25-4.50 mg/ml, in distilled and tap water media. The results showed that maggot extract possesses significant (P&lt;0.05) larvicidal activities against the mosquito species, in a way akin to those reported for potent plant extracts. The larvicidal activities of the extract was dose dependent; and extract induced significantly higher larval mortality in tap water bio-assay medium than distilled water, except in the 0.25 mg/ml concentration treatment, where the reverse was the case. While, 100% larval mortality was recorded in extract concentration of 2.50 mg/ml in tap water, it took 4.50 mg/ml to kill all exposed larvae in distilled water bio-assay media. The LC50 values of the extract ranged significantly (P&lt;0.05) from 1.57 mg/ml in tap water to 2.26 mg/ml in distilled water. The LC90 equivalents were 2.14 mg/ml and 3.47 mg/ml, respectively. These results suggest that insects may be at-least as promising as the botanicals in our search for eco-friend alternative insecticides.Key words: Bio-assay media, Insect metabolites, Insecticides, Larval mortality, Lethal Concentration and susceptibility

Assessment of the physicochemical characteristics, chemical and microbiological safety of two types of kilichi, a grilled meat produced in Niger

Production of kilichi, a grilled meat of West Africa, is a common method of meat preservation in Niger. Thirty samples of condiments‐coated kilichi and uncoated kilichi collected in Niger, were analyzed for microbiological contamination, as well as NaCl,protein and lipid contents, using standard methods. Contamination with Polycyclic Aromatic Hydrocarbons (PAHs) was also assessed using a HPLC–FLD technique. Highly significant differences (p < .001) were observed between coated kilichi and uncoated kilichi, for NaCl content (2.56% and 1.40%), for proteins (51% and 72%) and lipids (18% and 13%), respectively. Water activity was low in both kilichi, showing a potential microbial stability. Among the 15 European Union (EU) priority PAHs, 12 were detected in the samples. About 56.3% of coated kilichi samples exceeded the EU maximal limit for BaP, and 75% exceeded the EU maximal limit for the sum of 4 PAHs (PAH4). For uncoated kilichi, 28.6% of samples did not meet the standards for BaP and PAH4. About 6% of coated kilichi samples were not compliant with standards related to Staphylococcus aureus, Bacillus cereus, Clostridium perfringens, and 31%,50% for yeasts and fungi, respectively. Escherichia coli and Enterobacteria were below the detection limit in both kilichi, but Salmonella and Bacillus cereus were detected only in one coated kilichi. The noncompliant samples of uncoated kilichi were in the proportions varying between 7% –86% for S. aureus, C. perfringens, yeasts, and fungi. This study showed potential risks associated with the consumption of traditionally produced kilichi in Niger due to both PAHs and pathogen bacteria contamination