Self Care system for Heart Failure out of hospital patients

CUORE is a Heart Failure (HF) Disease Assessment System that makes use of innovative approaches, based on Information Technologies (IT) and portable monitoring devices, for the continuous assessment of HF progression and cardiovascular risk stratification. The system valuates the cardiac condition integrating patient data from different sources with special emphasis in the information obtained for ECG processing. Rather than just evaluate the cardiovascular status, the system also aims to motivate patients to have an active role in their health management and to improve their cardiac condition by promotion of an active lifestyle. In order to make the system usable the methodology adopted to create the final solution is iterative and it involves users in all stages. This paper presents the conceptualization of CUORE as a solution to self care for heart failure out of hospital patients

AIoTES: Setting the principles for semantic interoperable and modern IoT-enabled reference architecture for Active and Healthy Ageing ecosystems

[EN] The average life expectancy of the world's population is increasing and the healthcare systems sooner than later will be compromised by its reduced capacity and its highly economic cost; in addition, the age distribution of the population is leading towards the older spectrum. This trend will lead to immeasurable and unexpected economic problems and social changes. In order to face up this challenge and complex economic and social problem, it is necessary to rely on the appropriate digital tools and technological infrastructures for ensuring that the elderly are properly cared in their everyday living environments and they can live independently for longer. This article presents ACTIVAGE IoT Ecosystem Suite (AIoTES), a concrete reference architecture and its implementation process that addresses these issues and that was designed within the first European Large Scale Pilot, ACTIVAGE, a H2020 funded project by the European Commission with the objective of creating sustainable ecosystems for Active and Healthy Ageing (AHA) based on Internet of Things and big data technologies. AIoTES offers platform level semantic interoperability, with security and privacy, as well as Big Data and Ecosystem tools. AIoTES enables and promotes the creation, exchange and adoption of crossplatform services and applications for AHA. The number of existing AHA services and solutions are quite large, especially when state-of-the-art technology is introduced, however a concrete architecture such as AIoTES gains more importance and relevance by providing a vision for establishing a complete ecosystem, that looks for supporting a larger variety of AHA services, rather than claiming to be a unique solution for all the AHA domain problems. AIoTES has been successfully validated by testing all of its components, individually, integrated, and in real-world environments with 4345 direct users. Each validation is contextualized in 11 Deployment Sites (DS) with 13 Validation Scenarios covering the heterogeneity of the AHA-IoT needs. These results also show a clear path for improvement, as well as the importance for standardization efforts in the ever-evolving AHA-IoT domain.We thank to all the people who have participated in the development and validation of AIoTES. This work has been developed under the framework of the ACTIVAGE project. The project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 732679.Valero-López, CI.; Medrano-Gil, A.; González-Usach, R.; Julián-Seguí, M.; Fico, G.; Arredondo, MT.; Stavropoulos, TG.... (2021). AIoTES: Setting the principles for semantic interoperable and modern IoT-enabled reference architecture for Active and Healthy Ageing ecosystems. Computer Communications. 177:96-111. https://doi.org/10.1016/j.comcom.2021.06.0109611117

Impact of interstitial lung disease on the survival of systemic sclerosis with pulmonary arterial hypertension

To assess severity markers and outcomes of patients with systemic sclerosis (SSc) with or without pulmonary arterial hypertension (PAH-SSc/non-PAH-SSc), and the impact of interstitial lung disease (ILD) on PAH-SSc. Non-PAH-SSc patients from the Spanish SSc registry and PAH-SSc patients from the Spanish PAH registry were included. A total of 364 PAH-SSc and 1589 non-PAH-SSc patients were included. PAH-SSc patients had worse NYHA-functional class (NYHA-FC), worse forced vital capacity (FVC) (81.2 ± 20.6% vs 93.6 ± 20.6%, P < 0.001), worse tricuspid annular plane systolic excursion (TAPSE) (17.4 ± 5.2 mm vs 19.9 ± 6.7 mm, P < 0.001), higher incidence of pericardial effusion (30% vs 5.2%, P < 0.001) and similar prevalence of ILD (41.8% vs. 44.9%). In individuals with PAH-SSc, ILD was associated with worse hemodynamics and pulmonary function tests (PFT). Up-front combination therapy was used in 59.8% and 61.7% of patients with and without ILD, respectively. Five-year transplant-free survival rate was 41.1% in PAH-SSc patients and 93.9% in non-PAH-SSc patients (P < 0.001). Global survival of PAH-SSc patients was not affected by ILD regardless its severity. The multivariate survival analysis in PAH-SSc patients confirmed age at diagnosis, worse NYHA-FC, increased PVR, reduced DLCO, and lower management with up-front combination therapy as major risk factors. In conclusion, in PAH-SSc cohort risk of death was greatly increased by clinical, PFT, and hemodynamic factors, whereas it was decreased by up-front combination therapy. Concomitant ILD worsened hemodynamics and PFT in PAH-SSc but not survival regardless of FVC impairment

Impact of interstitial lung disease on the survival of systemic sclerosis with pulmonary arterial hypertension

To assess severity markers and outcomes of patients with systemic sclerosis (SSc) with or without pulmonary arterial hypertension (PAH-SSc/non-PAH-SSc), and the impact of interstitial lung disease (ILD) on PAH-SSc. Non-PAH-SSc patients from the Spanish SSc registry and PAH-SSc patients from the Spanish PAH registry were included. A total of 364 PAH-SSc and 1589 non-PAH-SSc patients were included. PAH-SSc patients had worse NYHA-functional class (NYHA-FC), worse forced vital capacity (FVC) (81.2 +/- 20.6% vs 93.6 +/- 20.6%, P < 0.001), worse tricuspid annular plane systolic excursion (TAPSE) (17.4 +/- 5.2 mm vs 19.9 +/- 6.7 mm, P < 0.001), higher incidence of pericardial effusion (30% vs 5.2%, P < 0.001) and similar prevalence of ILD (41.8% vs. 44.9%). In individuals with PAH-SSc, ILD was associated with worse hemodynamics and pulmonary function tests (PFT). Up-front combination therapy was used in 59.8% and 61.7% of patients with and without ILD, respectively. Five-year transplant-free survival rate was 41.1% in PAH-SSc patients and 93.9% in non-PAH-SSc patients (P < 0.001). Global survival of PAH-SSc patients was not affected by ILD regardless its severity. The multivariate survival analysis in PAH-SSc patients confirmed age at diagnosis, worse NYHA-FC, increased PVR, reduced DLCO, and lower management with up-front combination therapy as major risk factors. In conclusion, in PAH-SSc cohort risk of death was greatly increased by clinical, PFT, and hemodynamic factors, whereas it was decreased by up-front combination therapy. Concomitant ILD worsened hemodynamics and PFT in PAH-SSc but not survival regardless of FVC impairment

Process Choreography for Human Interaction Computer-Aided Simulation

Design errors can suppose a unaffordable load for the production costs. Allowing product designers to de ne behavioral patterns that describe the interaction of future users of the system can reduce the number of design errors. These patterns can be used to simulate how users respond to stimuli of products detecting problems at early stages of product development. Choreography systems to simulate the interaction among devices and services defined using commercially available workflow engines have been used in previous work (as the European project VAALID). However, the complexity of human behavior models requires much more expressive workflow languages for their definition. In this work, a highly expressive Workflow engine is presented. This system solves the problem of expressiveness in the representation of the interaction of human behavior models in the VAALID projectFernández Llatas, C.; Mocholi Agües, JB.; Sala Soriano, MP.; Naranjo Martinez, J. (2011). Process Choreography for Human Interaction Computer-Aided Simulation. Lecture Notes in Computer Science. 6761:214-220. doi:10.1007/978-3-642-21602-2_24S214220676

universAAL: Towards the Assisting Technologies Market Breakthrough

The universAAL initiative aims at fulfilling EU objectives to promote open platforms in the Ambient Assisted Living domain by: (1) producing a platform providing the necessary technical support; (2) carrying out support activities promoting widespread acceptance and adoption of the platform. Coordinated exploitation models to ensure the sustainability of project results are being developed by a partnership of committed partners in order to deliver the evidence of usefulness, usability, and reliability of the universAAL platform while assuring its maintenance, thus making universAAL a unique candidate for re-use under real-life conditionsSala Soriano, MP.; Guillén Barrionuevo, SG.; Naranjo Martinez, J.; Lazaro Ramos, JP.; Gorman, J. (2013). universAAL: Towards the Assisting Technologies Market Breakthrough. Studies in Health Technology and Informatics. 189:187-192. doi:10.3233/978-1-61499-268-4-187S18719218

Implementation of the ISO/IEC 24756 for the Interaction Modeling of an AAL Space

This paper presents the results of the implementation of an accessibility verifier tool for AAL systems using the ISO/IEC 24756 standard. The accessibility verifier tool is based in an interaction model where the Common Accessibility Profile (CAP), as defined by the standard, is used to perform the checking of the accessibility constrains of the system configuration against the user capabilities. The paper gives information of the major design decisions in developing the tool, the context of use in the VAALID project and the relation with the standardSala Soriano, MP.; Fernández Llatas, C.; Mocholi Agües, JB.; Presencia Ortí, PL.; Naranjo Martinez, J. (2011). Implementation of the ISO/IEC 24756 for the Interaction Modeling of an AAL Space. Lecture Notes in Computer Science. 6767:210-219. doi:10.1007/978-3-642-21666-4_24S210219676

Conjoint PERSONA – SOPRANO Workshop 1

Abstract. Being both EU-IST integrated projects in the field of AAL, PERSONA and SOPRANO organized a conjoint workshop on the occasion of the AmI-07 conference in order for the researchers of the projects to exchange insights of the approaches to the key field challenges, the achievements so far in each of the projects, and possible synergies in the future. Here, we summarize the exchanged info and the workshop results. The paper gives a good overview of the two projects and their status by the end of October 2007. Keywords: EU-IST integrated project, ambient intelligence, assisted living, use cases and scenarios, architectural design, technological approach

Impact of late presentation of HIV infection on short-, mid- and long-term mortality and causes of death in a multicenter national cohort : 2004-2013

To analyze the impact of late presentation (LP) on overall mortality and causes of death and describe LP trends and risk factors (2004-2013). Cox models and logistic regression were used to analyze data from a nation-wide cohort in Spain. LP is defined as being diagnosed when CD4 < 350 cells/ml or AIDS. Of 7165 new HIV diagnoses, 46.9% (CI:45.7-48.0) were LP, 240 patients died.First-year mortality was the highest (aHR = 10.3[CI:5.5-19.3]); between 1 and 4 years post-diagnosis, aHR = 1.9(1.2-3.0); an

Comunicación multisensorial

Compendio de las reflexiones que sobre el trabajo diario han realizado un grupo de profesionales de Educación Especial en el seno del Seminario de Centros de Educación Especial y Recursos de la Región de Murcia, cuyo objetivo ha sido proporcionar a los alumnos una educación de calidad en un marco de buenas prácticas de enseñanza. El trabajo consta de una fundamentación teórica sobre lo que este grupo de profesionales entiende por 'Comunicación Multisensorial', haciendo un recorrido por las diferentes fuentes teóricas de las cuales se han servido para la realización de este trabajo. Una segunda parte en la que se ofrecen orientaciones para el plan de trabajo individualizado. En la tercera parte se presentan los materiales, sus características y usos con una explicación de cada uno de ellos, así como recomendaciones para su uso. La última parte se dedica a la evaluación en la que se ofrecen tres tipos de documentos: fichas de seguimiento para cada área, registro de evaluación de Comunicación Multisensorial y un boletín informativo para las familias.MurciaES