98 research outputs found

    Elimination of illegally obtained evidence as a guarantee of compliance of the Polish criminal process with fair trial requirements

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    Zdigitalizowano i udostępniono w ramach projektu pn. Rozbudowa otwartych zasobów naukowych Repozytorium Uniwersytetu w Białymstoku, dofinansowanego z programu „Społeczna odpowiedzialność nauki” Ministra Edukacji i Nauki na podstawie umowy SONB/SP/512497/2021Przedmiotem rozważań Autorzy uczynili zagadnienie eliminacji dowodów nielegalnych w polskim postępowaniu karnym. Jest to tematyka bardzo istotna z punktu rzetelności procesu bowiem prawidłowe procedowanie w zakresie gromadzenia dowodów jest jednym z jego determinantów. Zagadnienie eliminacji dowodów nielegalnych ważne jest także dla konsensualnych form zakończenia postępowania karnego, a szczególnie dla „skazania bez rozprawy” (art. 335 w zw. z art. 343 kpk.) oraz dobrowolnego poddania się karze (art. 387 kpk.). Co ciekawe w polskim procesie karnym nie ma konkretnej regulacji w zakresie eliminacji dowodów nielegalnych, dlatego też w opracowaniu zaproponowano różne rozwiązania w tym zakresie. Autorzy wskazują także na kontrowersje związane z zakazem wykorzystania owoców zatrutego drzewa, który choć nie ma swego miejsca w przepisach kodeksu postępowania karnego zaczyna być realnie widoczny w orzecznictwie. W związku z powyższym Autorzy stanęli na stanowisku, że organ procesowy naruszający warunki legalności dokonania podsłuchu, przeszukania, lub kontroli korespondencji czy też np. prowokacji, przekreśla dopuszczalność dowodowego wykorzystania wyników swojego działania.Katarzyna T. Boratyńska - Departament of Criminal Procedure of the Faculty of Law, University in Białystok (Poland)Andrzej Sakowicz – Department of Criminal Law of the Faculty of Law, University in Białystok (Poland)11714

    Field Effect Transistors for Terahertz Detection: Physics and First Imaging Applications

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    Resonant frequencies of the two-dimensional plasma in FETs increase with the reduction of the channel dimensions and can reach the THz range for sub-micron gate lengths. Nonlinear properties of the electron plasma in the transistor channel can be used for the detection and mixing of THz frequencies. At cryogenic temperatures resonant and gate voltage tunable detection related to plasma waves resonances, is observed. At room temperature, when plasma oscillations are overdamped, the FET can operate as an efficient broadband THz detector. We present the main theoretical and experimental results on THz detection by FETs in the context of their possible application for THz imaging.Comment: 22 pages, 12 figures, review pape

    A potent chemotherapeutic strategy in prostate cancer: S-(methoxytrityl)-L-cysteine, a novel Eg5 inhibitor

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    Docetaxel-based combination chemotherapy remains the predominant treatment for castration-resistant prostate cancer. However, taxane-related drug resistance and neurotoxicity have prompted us to develop substitute treatment strategies. Eg5 (kinesin spindle protein), which is crucial for bipolar spindle formation and duplicated chromosome separation during the early phase of mitosis, has emerged as an attractive target for cancer chemotherapy. The aim of this study was to investigate the anticancer efficacy of S-(methoxytrityl)-ℒ-cysteine (S(MeO)TLC), a novel Eg5 inhibitor in prostate cancer. Eg5 expression was examined in human prostate cancer cell lines and tissue microarrays were constructed from clinical specimens. Antiproliferative activity of S(MeO)TLC in prostate cancer cells was assessed by a cell viability assay. The anticancer effect and inhibitory mechanism of S(MeO)TLC in prostate cancer cells was further explored by Hoechst staining, flow cytometry and immunofluorescence. In addition, the antitumor effect of S(MeO)TLC on subcutaneous xenograft models was assessed. Eg5 expression was identified in PC3, DU145 and LNCaP cells. More than half of prostate cancer clinical specimens displayed Eg5 expression. S(MeO)TLC exhibited more powerful anticancer activity in prostate cancer cells compared with the other four Eg5 inhibitors tested. S(MeO)TLC induced cell death after arresting dividing cells at mitosis with distinct monopolar spindle formation. S(MeO)TLC exhibited its significant inhibitory activity (P<0.05) on subcutaneous xenograft models also through induction of mitotic arrest. We conclude that Eg5 is a good target for prostate cancer chemotherapy, and S(MeO)TLC is a potent promising anticancer agent in prostate cancer

    Purinergic signalling and immune cells

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    This review article provides a historical perspective on the role of purinergic signalling in the regulation of various subsets of immune cells from early discoveries to current understanding. It is now recognised that adenosine 5'-triphosphate (ATP) and other nucleotides are released from cells following stress or injury. They can act on virtually all subsets of immune cells through a spectrum of P2X ligand-gated ion channels and G protein-coupled P2Y receptors. Furthermore, ATP is rapidly degraded into adenosine by ectonucleotidases such as CD39 and CD73, and adenosine exerts additional regulatory effects through its own receptors. The resulting effect ranges from stimulation to tolerance depending on the amount and time courses of nucleotides released, and the balance between ATP and adenosine. This review identifies the various receptors involved in the different subsets of immune cells and their effects on the function of these cells

    Investigation of rotational motion in a reinforced concrete frame construction by a fiber optic gyroscope

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    This paper deals with an issue of a rotational motion impact on a construction and presents civil engineering applications of a fiber optic rotational seismograph named Fiber-Optic System for Rotational Events & Phenomena Monitoring. It has been designed for a long- term building monitoring and structural rotations’ recording. It is based on the Sagnac effect which enables to detect one-axis rotational motion in a direct way and without any reference system. It enables to detect a rotation component in the wide range of a signal amplitude from 10-8 rad/s to 10 rad/s, as well as a frequency from DC to 1000 Hz. Data presented in this paper show the behavior of a reinforced concrete frame construction on different floors. Several measurements were carried out by placing the applied sensor on different floor levels of a building. The laboratory and in-situ measurements confirmed that Fiber-Optic System for Rotational Events & Phenomena Monitoring is an accurate and suitable device for applications in civil engineering
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