THE STATE OF SECURITY ISSUANCE IN FINANCIAL SECTOR OF OUR COUNTRY

The article examines the current state of securities issuance in the financial sector of the country. The study covers the use of investment forms as complementary parts rather than being competitive. It highlights the fact that during the years of independence, real investment in the economy formed the basis of public investment programs and it addresses some issues regarding the state of securities issuance in the financial sector of the economy

Использование информационно-коммуникационных технологий для экспорта экономических субъектов Самаркандской области

This article is aimed at improving the use of information and communication technologies to support the export of entrepreneurship, covering the processes of further expansion of business activity and creating conditions for domestic producers, including their export to foreign markets and exports

Slow-roll inflation in (R+R*4) gravity

We reconsider the toy-model of topological inflation, based on the R*4-modified gravity. By using its equivalence to the certain scalar-tensor gravity model in four space-time dimensions, we compute the inflaton scalar potential and investigate a possibility of inflation. We confirm the existence of the slow-roll inflation with an exit. However, the model suffers from the eta-problem that gives rise to the unacceptable value of the spectral index n_s of scalar perturbations.Comment: 12 pages, 3 figures, LaTeX, misprints corrected and references update

ИССЛЕДОВАНИЕ УСТАНОВИВШИХСЯ РЕЖИМОВ РАБОТЫ ЧАСТОТНО-УПРАВЛЯЕМОГО АСИНХРОННОГО ГЕНЕРАТОРА ВЕТРОЭЛЕКТРИЧЕСКИХ УСТАНОВОК

The paper proposes an analytical expression for calculating a manipulated variable of stator voltage in a frequency-controlled induction generator with a cage rotor of a wind power plant while regulating a constant value of the absolute slip of the generator. Comparison of the calculated results by the proposed expression and full differential equations of the generator (an equation of state) at steady state has confirmed a high accuracy of the analytical expression.Предложено аналитическое выражение для расчета регулируемой величины статорного напряжения частотно-управляемого асинхронного генератора с короткозамкнутым ротором ветроэлектрической установки при регулировании на постоянство величины абсолютного скольжения генератора. Сопоставление результатов расчета по предложенному выражению и по полным дифференциальным уравнениям генератора (уравнения состояния) при установившемся режиме подтвердило высокую точность аналитического выражения

Association of angiotensinogen and angiotensin II receptor type I polymorphisms with biomarkers of carbohydrate and lipid metabolism in Dagestan residents with type 2 diabetes and hypertension

Aim. To study the associations of angiotensinogen (AGT) (s4762(С521Т), rs699(Т704C)) and angiotensin II receptor type I (AGTR1) (rs5186(A1166C)) genetic polymorphisms with serum levels of insulin, glucagon, C-peptide, leptin, as well as with dyslipidemia and glycemic levels in Dagestan residents with combination of type 2 diabetes (T2D) and hypertension (HTN), as well as with isolated T2D/HTN.Material and methods. We examined 16 patients with isolated T2D, 59 patients with T2D+HTN and 51 patients with isolated HTN from Dagestan. Genetic polymorphisms of the AGT and AGTR1 genes were studied. The levels of insulin, glucagon, C-peptide, and leptin were studied by enzyme-linked immunosorbent assay (ELISA), while lipid and carbohydrate metabolism — by biochemical methods.Results. In patients with T2D, the association of CC genotype of AGT gene rs4762(С521Т) polymorphism with a leptin decrease was determined, while its CT genotype was associated with an increase in serum level of triglycerides. The TC genotype of AGT gene rs699(Т704C) polymorphism was associated with an increase in leptin, triglyceride and glucose levels. The AA genotype of AGTR1 gene rs5186(A1166C) polymorphism was associated with an increase in insulin and glucose levels, as well as a decrease in leptin level. In patients with a combination of T2D and HTN, CC and CT genotypes of AGT gene rs4762(С521Т) polymorphism was associated with a decrease in glucagon level. The TT genotype of AGT gene rs699(Т704C) polymorphism was associated with an increase in insulin, triglyceride, glucose and body mass index (BMI) levels. In isolated HTN, the CC and CT genotypes of AGT gene rs4762(С521Т) polymorphism were associated ith a decrease in glucagon level. The TT genotype of AGT gene rs699(Т704C) polymorphism was associated with increased levels of insulin, low density lipoproteins, and BMI.Conclusion. Associations of AGT (s4762(С521Т), rs699(Т704C)) and AGTR1 (rs5186(A1166C)) genetic polymorphisms with carbohydrate and lipid metabolism changes are an important pathogenetic link of T2D and HTN, which allows developing an individual prognosis of these diseases in Dagestan residents

Comparative estimation of efficiency of using the ozonized physiological solution before the adenomectomia operation

140 operated patients with purulent-inflammatory process of the bladder and with adenoma pros-tate were under our supervision. 70 patients of them have made the control group, with the tradi-tional complex treatment was carried out. 70 patients were included in the basic group-the seance of ozonotheraphy was carried out on them before and after operation. The comparative analysis of efficiency of the method of ozoning, offered by us, was car-ried out on the clinic- laboratory data. The improvement almost of all researched par aments led to decrease of after operation complications of the basic group patients on 11%.Besides, the ozonotheraphy efficiency is proved by speed rehabilitation of the patients and by opportunity of their, discharge from hospital for three days sooner the patients of the control group, with smaller expression of dizuria symptoms.Под нашим наблюдением находились 140 прооперированных больных с гнойно-воспалительными заболеваниями мочевого пузыря и ложа аденомы, которым были наложены эпицистостомы. Из них 70 пациентов составили контрольную группу, которым было проведено традиционное комплексное лечение, 70 пациентов вошли в основную группу, им проведена была предоперационная подготовка после озонотерапии. Сравнительный анализ эффективности предложенного нами метода озонирования про-водился по клинико-лабораторным данным. Улучшение почти всех исследуемых показателей привело к снижению послеоперационных осложнений у больных основной группы на 11%. Кроме того, эффективность озонотерапии обосновывается скорой реабилитацией больных в после операционном периоде и возможность их выписки на 3 дня раньше пациентов контрольной группы

Microhardness of Polyketone Irradiated by Gamma Rays Co60

The effect of radiation on the microhardness of polyketone has been studied. When ex-posed to gamma irradiation, the near-surface and bulk microhardness increases. The values of microhardness at a load of 10 g increased by 14%, and at a load of 100 g by 20%, respectively.Исследование проводилось в рамках программы научно-исследовательских работ Института ядерной физики Академии наук Республики Узбекистана на 2020-2024 годы, по теме «Радиационно - стимулированные процессы при ядерной трансмутации легированного монокристаллического кремния» в лаборатории радиационной физики и техники твердотельной электроники

Fundamental approaches to the surgical treatment of fecal incontinence after surgical correction of anorectal malformations

The aim of this study was to improve treatment of fecal incontinence in children with damage to the sphincter apparatus of the rectum in the correction of anorectal defect. Method of separate colostomy is preferable because casting of the intestinal contents from the proximal part to the distal is avoided.Целью исследования явилось совершенствование методов лечения недержания кала у детей с повреждением сфинктерного аппарата при коррекции аноректального порока. Метод раздельной колостомии является предпочтительным, поскольку позволяет исключить заброс содержимого кишечника из проксимального отдела в дистальный