An Experimental Investigation of Material Removal Rate on H-13 Die Tool Steel on EDM Using Taguchi Techniques

H-13 is die tool steel, it have widely applications in the Hot punches and dies for blanking, bending, swaging and forging, Hot extrusion dies for aluminum, cores, ejector pins, inserts, Nozzles for aluminum, tin and lead die casting, Hot shear blades etc. as the H-13 steel has widely applications so it is chosen for the present study. Presents works shows the effect of various process parameters like peak current, Pulse on Time and Feed rate on Material Removal Rate. EDM Drilling and Taguchi technique is used for the optimization of response variables

Exploring Herbal Remedies for Anti-Leishmanial Activity: A Comprehensive Review

- Leishmaniasis remains a serious neglected illness worldwide, posing significant challenges in its treatment due to the side effects of existing medications and the rising cases of parasite resistance resulting from indiscriminate treatment. To address this issue, exploring complementary remedies using natural products presents a promising option by combining the empirical knowledge of local populations with scientific research on the medicinal properties of plants. Several studies have investigated herbal treatments for leishmaniasis; however, more research is needed to identify safe and non-toxic remedies. To consolidate the latest findings, researchers from around the globe have compiled a comprehensive article on herbal and organic medicines used to treat leishmaniasis. While many medicinal plants have not been extensively studied, promising candidates have undergone prospective clinical trials. Recent articles have explored the active constituents of these medicinal plants, such as quinones, phenolic compounds, lignans, tannins, terpenes, and oxylipins, shedding light on their potential therapeutic benefits. Pharmacognosy views medicinal plants as valuable sources for developing novel medications and supporting traditional therapies, offering a practical approach to managing various illnesses. In summary, harnessing the power of natural goods and integrating traditional knowledge with scientific research provides a viable and desirable strategy to combat leishmaniasis, promoting safer and more effective treatment options in the future

Chronic Active Hepatitis B with HBV-Associated Nephropathy: Close Resemblance to Lupus Nephritis

We present a rare case of a 23-year-old male incidentally detected with hepatitis B virus (HBV) infection presenting with features suggestive of HBV-associated nephropathy. A renal biopsy specimen suggested a mesangioproliferative glomerulonephritis with a full-house pattern on immunoflourescence consistent with a diagnosis of diffuse lupus nephritis. Glomerular HbeAg and HbsAg antigens were not detectable by immunofluorescence. Antiviral therapy was instituted to suppress viral replication, thereby leading to clinical and virological remission, including that of the glomerulonephritis, without the need for additional immunosuppressant therapy. This case depicts the uniqueness of the presentation of the two conditions mimicking each other, the strategy adopted to prevent the activation of viral replication and the achievement of clinical remission

Groundwater hydrochemistry of Rajnandgaon district, Chhattisgarh, Central India

The spreading of fluorosis diseases in Central India related to high concentrations of fluoride ion (F−) is a cause of major concern. In this work, the hydrochemistry of the aquifers related to Seonath River, in Rajnandgaon district, Chhattisgarh state, India, has been studied, focusing on the presence and sources of F−. Hydrochemical parameters were analyzed in the post-monsoon season in 160 wells located in nine tehsils, finding F− concentrations ranging from 0.6 to 18.5 mg L−1. Seasonal variations were also studied in Chhuikhadan tehsil, in which the highest F− values were registered, finding a noticeable enrichment in the pre-monsoon months. In many locations of the district, F− concentrations exceeded the recommended value of 1.5 mg L−1, which have led to the appearance of several health issues. Multidimensional analysis statistical methods were adopted to investigate the sources of F−, and the mineralization of bedrock elements into the groundwater was observed to be the primary source

Assessment of arsenic and heavy metal pollution in Chhattisgarh, India

Natural contamination of arsenic (As) and heavy metals (HMs) poses a health threat in many regions. Ambagarh Tehsil, Rajnandgaon, Central India, is a heavily polluted area due to mineralization of geogenic As and HMs in the environment, i.e., water, plants, and soil. In this work, contamination extents and sources of As and HMs (Cr, Mn, Cu, Zn, and Pb) in water, soil, and common plants were investigated to understand the main entry route of these toxic elements in human and domestic animals. The mean concentrations of total As in surface water, groundwater, surface soil, plant leaves, and animal stool samples of 0.031±0.009¿¿mg¿mL-1, 0.360±0.114¿¿mg¿mL-1, 192±65¿¿mg¿kg-1, 5.61±4.78¿¿mg¿kg-1, and 51.0±7.6¿¿mg¿kg-1, respectively, were found. The speciation, sources, enrichment, and toxicities of the As and other HMs are discussed, together with some associated health hazards, exemplified in domestic animals exposed to the contaminated water and food

Mycobacterium tuberculosis H37Ra: a surrogate for the expression of conserved, multimeric proteins of M.tb H37Rv

Additional file 3. Details of primers used, experimental and theoretical molecular weights, pI values and details of post-translational modifications in GAPDH

Dynamics of Hot QCD Matter -- Current Status and Developments

The discovery and characterization of hot and dense QCD matter, known as Quark Gluon Plasma (QGP), remains the most international collaborative effort and synergy between theorists and experimentalists in modern nuclear physics to date. The experimentalists around the world not only collect an unprecedented amount of data in heavy-ion collisions, at Relativistic Heavy Ion Collider (RHIC), at Brookhaven National Laboratory (BNL) in New York, USA, and the Large Hadron Collider (LHC), at CERN in Geneva, Switzerland but also analyze these data to unravel the mystery of this new phase of matter that filled a few microseconds old universe, just after the Big Bang. In the meantime, advancements in theoretical works and computing capability extend our wisdom about the hot-dense QCD matter and its dynamics through mathematical equations. The exchange of ideas between experimentalists and theoreticians is crucial for the progress of our knowledge. The motivation of this first conference named "HOT QCD Matter 2022" is to bring the community together to have a discourse on this topic. In this article, there are 36 sections discussing various topics in the field of relativistic heavy-ion collisions and related phenomena that cover a snapshot of the current experimental observations and theoretical progress. This article begins with the theoretical overview of relativistic spin-hydrodynamics in the presence of the external magnetic field, followed by the Lattice QCD results on heavy quarks in QGP, and finally, it ends with an overview of experiment results.Comment: Compilation of the contributions (148 pages) as presented in the `Hot QCD Matter 2022 conference', held from May 12 to 14, 2022, jointly organized by IIT Goa & Goa University, Goa, Indi

Voltage Profile Improvement of Transmission Lines Using Static VAR Compensator

ABSTRACT: In the present scenario the power system are operated nearer to their stability limits due to economic and environmental reasons. Now days a stable and secure operation of a power system is therefore a very important and challenging issue. Efficient transmission of voltage and stable operation of the power system is very much essential. The stability has been given much attention by power system researchers and planners in recent years, and is being regarded as one of the major sources of power system problems and insecurity. To compensate these problems in transmission system svc is used. A static VAR compensator is chosen as a low cost solution to replace a conventional capacitor bank, thus allowing a continuous and flexible nodal voltage adjustment. Due to simplest structure, easy designing and low cost, PI controller is used in SVC as voltage regulator is used to regulate the voltage in most industries. In this paper shunt FACTS device-SVC is used in transmission line for improving the voltage profile and stability. MATLAB Simulink platform has been used in this study. KEYWORDS: shunt device, transmission line, MATLAB, SVC, voltage stability. I.INTRODUCTION Static VAR Compensators can be very effective in controlling voltage fluctuations at rapidly varying loads. Unfortunately, the price for such flexibility is high. Nevertheless, they are often the only cost-effective solution for many loads located in remote areas where the power system is weak As the disturbance are arises in the system due any abnormal condition of fault, it goes to transient oscillations. These unwanted oscillations can change the performance characterics of applications. Hence this is required to control and is done by the use the same shunt FACTS device Static VAR Compensator (SVC) designed with auxiliary controllers Hence there is a requirement of devices which can control the random fluctuations and the transient oscillations comes in the transmission line voltage during transmission. It is necessary that system has very less overshoot and very less settling time for retain of voltage in steady level. So for this from the last few years static VAR compensator plays an important role in voltage regulation in AC Transmission Systems. A Static VAR Compensators provides such system improvements and benefits by controlling Shunt reactive power sources, both capacitive and inductive, with fast power electronic switching devices. The shunt connected, fixed or mechanically switched reactors are applied to minimize th

Reactivity and kinetic study of high ash Indian coal and biomass blends

In the present study, char samples of two biomasses and their blends with high ash Indian coal wee prepared at 900°C and then gasified in the temperature range of 850°C to 1000°C in Co2 atmosphere using thermogravimetric analyzer (TGA). It is observed that the char gasification reactivity of coal-biomass blend is lesser in comparison with the gasification reactivity of pure biomass. The effect of gasification temperature on reactivity as well as comparison between gasification of two pure biomasses and their blends with coal have been studied. The activation energy of biomass and their blends has also been discussed in this paper. The gasification reactivity and kinetic data developed from thermogravimetric analysis study may be useful for modeling and designing of suitable gasifier as per the available feedstocks