Sterile acellular dermal collagen as a treatment for rippling deformity of breast.

Prosthetic implants are frequently used for breast augmentation and breast reconstruction following mastectomy. Unfortunately, long-term aesthetic results of prosthetic breast restoration may be hindered by complications such as rippling, capsular contracture, and implant malposition. The advent of use of acellular dermal matrices has greatly improved the outcomes of prosthetic breast reconstruction. We describe a case of rippling deformity of breast that was treated using an acellular dermal matrix product, AlloMax. The patient presented with visible rippling of bilateral prosthetic breast implants as well as significant asymmetry of the breasts after multiple excisional biopsies for right breast ductal carcinoma in situ. A 6 × 10 cm piece of AlloMax was placed on the medial aspect of each breast between the implant and the skin flap. Follow-up was performed at 1 week, 3 months, and 1 year following the procedure. The patient recovered well from the surgery and there were no complications. At her first postoperative follow-up the patient was extremely satisfied with the result. At her 3-month and 1-year follow-up she had no recurrence of her previous deformity and no new deformity

Total posterior leg open wound management with free anterolateral thigh flap: case and literature review.

Soft tissue coverage of the exposed Achilles tendon is a unique reconstructive challenge. In this report, we describe the management of a large posterior leg wound with exposed Achilles tendon using a free anterolateral thigh (ALT) flap. A careful review of alternative reconstructive options is included, along with their respective advantages and disadvantages. A 32-year-old white man suffered a fulminant right lower extremity soft tissue infection requiring extensive debridement of the entire posterior surface of the right leg. The resulting large soft tissue defect included exposure of the Achilles tendon. Reconstruction of the defect was achieved with an ALT flap and split-thickness skin graft for coverage of the Achilles tendon and gastrocnemius muscle, respectively. The patient was able to ambulate independently within 2 months of the procedure

Una revisión de la investigación de Global Reporting Initiative (GRI) con informes de sostenibilidad: conjunto de datos 1999-2020

This review paper aims to identify the main areas of studies in the field of the Global Reporting Initiative (GRI) research with sustainability reports. Using a bibliometric analysis, this study evaluated 955 published documents retrieved from the Scopus database to find a research review structure on GRI with sustainability topics from 1999 to 2020 by utilizing the bibliometric package in VOSviewer and Harzing’s Publish or Perish. This paper examined the most effective journals, authors, countries, institutions, subject area, keywords, citation, co-authorship, co-citation, bibliographic coupling, and co-occurrences networks. Also, this paper demonstrated the intellectual structure of the research and perceived obstacles to growth in the literature. The results show that the trend of publications has been growing over the past 20 years. This study offers a comprehensive understanding and publication of past studies trends and suggests that it will be a much greater number of articles in this field over the next decade which help the future direction of researchers in this area.Este trabajo tiene como objetivo identificar las principales áreas de estudio en la investigación de Global Reporting Initiative (GRI). Mediante un análisis bibliométrico, este estudio evaluó 955 documentos publicados recuperados de la base de datos Scopus para encontrar una estructura de revisión de la investigación sobre GRI con temas de sostenibilidad desde 1999 hasta 2020 utilizando el paquete bibliométrico de VOSviewer y Publish or Perish de Harzing. Este trabajo examinó las revistas, autores, países, instituciones, área temática, palabras clave, citación, coautoría, co-citación, acoplamiento bibliográfico y redes de co-ocurrencias más eficaces. Asimismo, este trabajo demostró la estructura intelectual de la investigación y los obstáculos percibidos para el crecimiento de la bibliografía. Los resultados muestran que en los últimos 20 años la tendencia de las publicaciones ha ido en aumento. Este estudio ofrece una comprensión global y la publicación de las tendencias de los estudios anteriores y sugiere que habrá un número mucho mayor de artículos en este campo durante la próxima década

Local u'g'r'i'z' Standard Stars in the Chandra Deep Field-South

Because several observing programs are underway in various spectral regimes to explore the Chandra Deep Field South (CDF-S), the value of local photometric standards is obvious. As part of an NOAO Surveys Program to establish u'g'r'i'z' standard stars in the southern hemisphere, we have observed the central region of the CDF-S to create local standards for use by other investigators using these filters. As a courtesy, we present the CDF-S standards to the public now, although the main program will not finish until mid-2005.Comment: Accepted by AJ (scheduled for October 2003 issue). 26 pages, 5 tables, 5 figures. High resolution version of Figure 7 available at http://home.fnal.gov/~dtucker/Southern_ugriz/index.htm

Urban Metabolism and Quality of Life in Informal Areas

The 21st century is known as the century of urbanization. Numerous debates are currently taking place to definecities and what they should aspire to be. A number of terms have appeared in this arena,such as sustainable city, eco-city and green city to name a few. However, the main question remains how to measure the performance of a city in regards tothese aims. In addition, it is vital to note that major urbanization activities take part in cities of the developing world, where informalization is synonym to urbanization, thus necessitating a profound study of informal areas and their potential role in achieving sustainable cities. This paper studies how acity performs in terms of consuming and producing resources and how they flow through its various systems, described as urban metabolism. The paper particularly discusses how informal areas perform regarding their metabolism, focusing on water flow through these areas as a priority identified by the residents. Imbaba district, one of the largest informal areas in Cairo, is investigated as a case study to determine the actual quality of life of local residents and their ecological footprint and to providepractical insights. The whole process depends on a multidisciplinary participatory research where the citizens and local community based organization are the focal point. In addition, the process depends on open source data and data sharing as a way to empower local communities to identify their needs and issues and hence their appropriate interventions. This is conducted through questionnaires and interviews to identify what the current conditions and processes in informal areas provide for the residents. The paper concludes with identifying points of leakages in the resources flows and the possible interventions to improve the quality of life in the area while maintaining an efficient use of local resources and minimizing the impact of urbanization of the ecological footprint of cities. This will assist cities to become more resilient in the face of water scarcity, and provide a more vibrant life for its residents

Concentrically Loaded Circular RC Columns Partially Confined with FRP

Wrapping reinforced concrete (RC) columns with fiber reinforced polymer (FRP) composites is effective in increasing their capacity. The current state of the art concentrates primarily on fully wrapped columns and few studies dealt with partially wrapped ones. The objective herein is to evaluate the effectiveness of partial wraps (or strips) and to develop a confined concrete compressive stress–strain (fc − εc) model that accounts for partial wrapping. Three-dimensional finite element (FE) models are generated to evaluate the influence of different parameters on the behavior of concentrically loaded RC circular columns that are partially and fully wrapped with FRP. The results indicated an increase in ductility as the number of FRP strips is increased, and revealed that longitudinal steel had little influence on the confined fc − εc relationship. The proposed fc − εc model, derived from the parametric study, accounts for the effect of partial and full confinement, the unconfined concrete strength f c, and yielding of transverse steel. Comparison of the results generated using the proposed model with FE and experimental results are in good agreement

Causality between Energy Consumption and Economic Growth in Pakistan

The objective of this study is to examine the causality between energy consumption and economic growth in Pakistan over the period of 1991 to 2006. Pakistan has been facing severe energy crises in the current period and the condition is deteriorating day by day. By applying technique of Granger causality and unit root test, the results infer that electric power consumption is granger causing GDP growth. The implications of the study are that energy conservation policy regarding consumption of energy would not lead to any side-effects on economic growth in Pakistan. The country needs a quantum jump in electricity generation in medium-term scenario to revert the possibilities of load shedding in future due to shrinking gap between demand and supply of electricity. Keywords: Granger test, GDP, energy consumption

Relationship between miR-335 and sterol levels after in vitro hypoxia-ischemia of primary brain cells

Background/Purpose: Cholesterol homeostasis is vital for synaptogenesis and myelination during fetal and neonatal brain development. Both brain and plasma sterol levels have been shown to be associated with outcomes in adult stroke, and animal studies have suggested brain and plasma sterol changes in neonatal hypoxic-ischemic brain injury. MicroRNA-335 (miR-335) has been associated with brain sterol metabolism and our preliminary data showed that sterol metabolism is dysregulated in the brain after hypoxic-ischemic injury in a mouse model. This study sought to describe the effect of oxygen-glucose deprivation in vitro on individual brain cell populations and to validate the associations between sterol levels and miR-335 levels. Lastly, we assessed the feasibility of transfecting miR-335 mimics or miRNA antagonists (antagomiRs) in these brain cell cultures to set up future experiments to alter miR-335 levels for neuroprotection. Methods: Primary cells were isolated from embryonic day 18 CD1 mouse brains. Cells were maintained in DMEM for mixed glial culture and Neurobasal media with B27 for neurons. Once astrocytes were confluent, microglia were separated from the mixed glial culture by shaking to provide pure cell populations. Each of the three cell types underwent oxygen and glucose deprivation (OGD: glucose/pyruvate/B27-free media, 1% O2, 5% CO2) for 4 hours followed by replacement of glucose/pyruvate/B27 and resumption of normoxia. At 24 hours after OGD, cells (n=12 wells OGD and 12 normoxia) were washed, counted, and sterols analyzed by LC-MS/MS, normalized to the number of cells/well. Additional cells underwent measurement of miR-335 expression using quantitative PCR and/or transfection with miR-335 mimic or antagomiR. Results: Although lanosterol is increased after OGD in neurons, desmosterol and cholesterol levels were decreased. In microglia and astrocytes, cholesterol levels were lower than in neurons but increased after OGD. MiR-335 expression in neurons and astrocytes were inverse to cholesterol level changes, though this association was not seen in microglia. Lastly, red fluorescent protein-labelled miR-335 mimic was visualized in both neurons and astrocytes after transfection and miR-335 expression changes were seen after transfection in astrocytes. Conclusions: Sterol levels are altered after OGD and may be associated with OGD changes. Transfection of miR-335 mimic and antagomiR is feasible and future studies using these tools will allow for better understanding of the effects of neonatal HIBI on sterol levels. This approach could allow for identification of targets to aid in developing therapeutics.https://digitalcommons.unmc.edu/chri_forum/1017/thumbnail.jp

Public Awareness Toward Healthy Life: Sample from Iraqi Community 2020

Background: People must develop a healthy lifestyle to have a longer and healthier life. Objective: to study the Public awareness toward healthy life of Iraqi community, and it relation with some of demographic variables. Method & persons: A cross-sectional study conducted from 20th June – 20th September 2022, through online questionnaire (google form) distributed through any available channels (e-mails, Viber, Chat, Messenger, WhatsApp, Telegram, Facebook groups) Results: Nine hundred and fifty-six Iraqi persons enrolled in this study, with age mean and standard deviation 32.67± 11.954; the highest percentage of participants 589(51.2%) aged ≤ 29 years, females 577(60.4%), currently married 480(50.2%), medical & health field worker 458(47.9%), while all the non- medical persons 498, (52.1%), {students 212(22.2%), government non-medical worker 146(15.3%). most of the participants 812(84.9%) had once to twice brushing their teeth, and 408(42.7%) had sometimes using Dental floss, while 376(39.3%) of them never using dental floss, and only 39(41.1%)of the participant had regular teeth examination also good overall teeth health only in 387(40.5%). Acceptant-lifestyle 767(80.2%), and only 15(1.6%) had food & water intake poor lifestyle, while in overall-checkup the majority had poor overall-checkup 561(58.7%), then acceptable overall checkup 290(30.3%). Conclusion: Most of the participant had acceptance lifestyle in concerned food and water but had poor Overall checkup for vision, teeth, blood pressure, sugar, lipid and Regular doctor checkup in general