1,630 research outputs found

    Increased erythrocyte osmotic fragility in hypothyroidism

    Get PDF
    Hypothyroidism a quite common thyroid disorder is often associated with anemia. Osmotic fragility is altered with an alteration of the thyroid profile. Hypothyroidism induced reduction of membrane cholesterol and compromised the activity of Na+K+ATPase and increased peroxidation of membrane lipids appear to be responsible for damaging the red blood corpuscle (RBC) membranes which alter the permeability of themembrane and thus ionic environment within the cell. The objective of this study was to evaluate the relation between the association of hypothyroidism and RBC membrane lipid peroxidation in the development of increased RBC osmotic fragility. A complete clinical history and biochemical investigations, including thyroid function tests namely, thyroid -stimulating hormone (TSH) and free T4 (fT4), RBC membrane osmotic fragility test by gradient concentration of NaCl, and RBC membrane peroxidation using thiobarbituric acid reactive substances (TBARS) tests were performed among thirty two hypothyroidism patients and healthy controls. Serum TSH & TBARS in the RBC membrane were significantly higher (P <0.001) than healthy controls which also showed a significant positive correlation (r =0.8, P =0.01) when compared without grouping. Osmotic fragility of RBC was found significantly increased among hypothyroid patients (P <0.001) at NaCl conc. of 0.3%, 0.4%, 0.5% & (P <0.05) at NaCl conc. of 0.6%. In conclusion, the results indicated that RBC osmotic fragility increases significantly in hypothyroidism possibility due to increased membrane lipid peroxidation as observed in the study

    Increased erythrocyte osmotic fragility in hypothyroidism

    Get PDF
    213-218Hypothyroidism a quite common thyroid disorder is often associated with anemia. Osmotic fragility is altered with an alteration of the thyroid profile. Hypothyroidism induced reduction of membrane cholesterol and compromised the activity of Na+K+ATPase and increased peroxidation of membrane lipids appear to be responsible for damaging the red blood corpuscle (RBC) membranes which alter the permeability of themembrane and thus ionic environment within the cell. The objective of this study was to evaluate the relation between the association of hypothyroidism and RBC membrane lipid peroxidation in the development of increased RBC osmotic fragility. A complete clinical history and biochemical investigations, including thyroid function tests namely, thyroid -stimulating hormone (TSH) and free T4 (fT4), RBC membrane osmotic fragility test by gradient concentration of NaCl, and RBC membrane peroxidation using thiobarbituric acid reactive substances (TBARS) tests were performed among thirty two hypothyroidism patients and healthy controls. Serum TSH & TBARS in the RBC membrane were significantly higher (P <0.001) than healthy controls which also showed a significant positive correlation (r =0.8, P =0.01) when compared without grouping. Osmotic fragility of RBC was found significantly increased among hypothyroid patients (P <0.001) at NaCl conc. of 0.3%, 0.4%, 0.5% & (P <0.05) at NaCl conc. of 0.6%. In conclusion, the results indicated that RBC osmotic fragility increases significantly in hypothyroidism possibility due to increased membrane lipid peroxidation as observed in the study

    Quantum homogenization in non-Markovian collisional model

    Full text link
    Collisional models are a category of microscopic framework designed to study open quantum systems. The framework involves a system sequentially interacting with a bath comprised of identically prepared units. In this regard, quantum homogenization is a process where the system state approaches the identically prepared state of bath unit in the asymptotic limit. Here, we study the homogenization process for a single qubit in the non-Markovian collisional model framework generated via additional bath-bath interaction. With partial swap operation as both system-bath and bath-bath unitary, we numerically demonstrate that homogenization is achieved irrespective of the initial states of the system or bath units. This is reminiscent of the Markovian scenario, where partial swap is the unique operation for a universal quantum homogenizer. On the other hand, we observe that the rate of homogenization is slower than its Markovian counter part. Interestingly, a different choice of bath-bath unitary speeds up the homogenization process but loses the universality, being dependent on the initial states of the bath units.Comment: 26 pages, 9 figures. Expanded version with some new figures. Accepted in New Journal of Physic

    Activities of fisheries co-operative societies in India to boost up and optimise the resources and economy of farmers: a review

    Get PDF
    Fisheries within India have significant financial, nutritional and socio-economic development prospects. The country has a diversified natural fishery resource. Fishermen have continuously undertaken fisheries activity throughout the country over decades and fisheries co-operatives have now been developed for cumulative production and effective regulation of fishery activities. It was observed that there have been many inconsistencies, mostly in the management of fisheries co-operatives; a few were effectively handled under active supervision and government backing, whereas many co-operatives are facing various problems for their existence. Effective administration of fisherman's co-operatives is critical for increasing fishing productivity and the socio-economic growth of fishermen. Co-operatives can help fishermen develop their skills and gather information about technology, marketing, and management. Co-operatives can improve productivity, processing, storing and transportation capabilities while also meeting financial demands. As a result, co-operative organisations may contend with multinational corporations by integrating competent management abilities with co-operative power. To do this, a nationwide research project focusing on different elements of fisheries co-operatives is recommended. The need for appropriate policy implications for such sustainable management of fisheries co-operatives in accordance with current technical advancements in the sector of aquaculture, environmental degradation and global warming has been highlighted

    Hazards of wind turbines on avifauna - A preliminary appraisal within the Indian context

    Get PDF

    Trianthema portulacastrum L.: Traditional medicine in healthcare and biology

    Get PDF
    127-145Medicinal plants are the major folk and traditional medicine for the prevention of diseases worldwide. Trianthema portulacastrum L. (family: Aizoaceae), a small perennial weed, found in the America, Africa, India, and other regions of the world, and are extensively used not only as medicine but also as vegetable for its various health benefits. Phytochemical analysis of T. portulacastrum reveals the presence of alkaloids, phytosterols, terpenoids, saponins, flavonoids and phenolic compounds. In vitro and in vivo studies have demonstrated its pharmacological and biological activities. Different parts of T. portulacastrum L. are conventionally being used as analgesic, anti-pyretic, lipid lowering and microbicide agent; and protect liver and kidney from carcinogen, inflammation and oxidant chemicals

    Trianthema portulacastrum L.: Traditional medicine in healthcare and biology

    Get PDF
    Medicinal plants are the major folk and traditional medicine for the prevention of diseases worldwide. Trianthema portulacastrum L. (family: Aizoaceae), a small perennial weed, found in the America, Africa, India, and other regions of the world, and are extensively used not only as medicine but also as vegetable for its various health benefits. Phytochemical analysis of T. portulacastrum reveals the presence of alkaloids, phytosterols, terpenoids, saponins, flavonoids and phenolic compounds. In vitro and in vivo studies have demonstrated its pharmacological and biological activities. Different parts of T. portulacastrum L. are conventionally being used as analgesic, anti-pyretic, lipid lowering and microbicide agent; and protect liver and kidney from carcinogen, inflammation and oxidant chemicals
    corecore