87 research outputs found

    Exploring noise-induced chaos and complexity in a red blood cell system

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    We investigate dynamical changes and its corresponding phase space complexity in a stochastic red blood cell system. The system is obtained by incorporating power noise with the associated sinusoidal flow. Both chaotic and non-chaotic dynamics of sinusoidal flow in red blood cell are identified by 0-1 test. Furthermore, dynamical complexity of the sinusoidal flow in the system is investigated by heterogeneous recurrence based entropy. The numerical simulation is performed to quantify the existence of chaotic dynamics and complexity for the sinusoidal blood flow.Comment: 10 page

    Biokinetic Mechanisms Linked With Musculoskeletal Health Disparities: Stochastic Models Applying Tikhonov\u27s Theorem to Biomolecule Homeostasis.

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    Multiscale technology and advanced mathematical models have been developed to control and characterize physicochemical interactions, respectively, enhancing cellular and molecular engineering progress. Ongoing tissue engineering development studies have provided experimental input for biokinetic models examining the influence of static or dynamic mechanical stimuli (Saha, A. K., and Kohles, S. S., 2010, “A Distinct Catabolic to Anabolic Threshold Due to Single-Cell Nanomechanical Stimulation in a Cartilage Biokinetics Model,” J. Nanotechnol. Eng. Med., 1(3) p. 031005; 2010, “Periodic Nanomechanical Stimulation in a Biokinetics Model Identifying Anabolic and Catabolic Pathways Associated With Cartilage Matrix Homeostasis,” J. Nanotechnol. Eng. Med., 1(4), p. 041001). In the current study, molecular regulatory thresholds associated with specific disease disparities are further examined through applications of stochastic mechanical stimuli. The results indicate that chondrocyte bioregulation initiates the catabolic pathway as a secondary response to control anabolic processes. In addition, high magnitude loading produced as a result of stochastic input creates a destabilized balance in homeostasis. This latter modeled result may be reflective of an injurious state or disease progression. These mathematical constructs provide a framework for single-cell mechanotransduction and may characterize transitions between healthy and disease states

    A novel implementation of Petrov-Galerkin method to shallow water solitary wave pattern and superperiodic traveling wave and its multistability: generalized Korteweg-de Vries equation

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    This work deals with the constitute of numerical solutions of the generalized Korteweg-de Vries (GKdV) equation with Petrov-Galerkin finite element approach utilising a cubic B-spline function as the trial function and a quadratic function as the test function. Accurateness and effectiveness of the submitted methods are shown by employing propagation of single solitary wave. The L2, L∞error norms and I1, I2and I3invariants are used to validate the applicability and durability of our numerical algorithm. Implementing the Von-Neumann theory, it is manifested that the suggested method is marginally stable. Furthermore, supernonlinear traveling wave solution of the GKdV equation is presented using phase plots. It is seen that the GKdV equation supports superperiodic traveling wave solution only and it is significantly affected by velocity and nonlinear parameters. Also, considering a superficial periodic forcing multistability of traveling waves of perturbed GKdV equation is presented. It is found that the perturbed GKdV equation supports coexisting chaotic and various quasiperiodic features with same parametric values at different initial condition

    Coronary atheroma [14 cm] extracted from the right coronary artery during off-pump coronary artery bypass grafting 

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    Coronary endarterectomy is a good option for surgical revascularization in diffusely coronary artery disease. In coronary artery bypass surgery, a diffusely diseased right coronary artery is an obstruction to accomplishing complete myocardial revascularization, subsequently increasing the likelihood of a poor postoperative prognosis. Here, we report a case of extraction of a long segment coronary atheroma (14 cm) from right coronary artery during off-pump coronary artery bypass grafting using closed endarterectomy technique followed by reconstruction with saphenous venous graft

    Health-related quality of life following heart surgery

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    This study evaluates the differences in preoperative and postoperative health-related quality of life of the patients following heart surgery and observed the factors that influence quality of life changes. This prospective observational study involved two parameters from the SF-36 questionnaire before and one year after heart surgery in a single surgeon’s practice. At the baseline assessment of the study observed 140 patients, predominantly were male in both study groups. The mean age was 56.8 ± 4.2 years, 64.7 ± 7.4 years in Group of patients age ≀ 60 years and age >60 year’s respectively. In elderly aged group, patients have greater risk of co-morbidity, operative complications, and low preoperative as well as postoperative quality of life score. There was an overall improvement in all majority health domains of the SF-36 questionnaire among study population. Statistical results from Logistic multivariate analysis demonstrates a greater value of preoperative mental component summary scores (p=0.08), and physical component summary scores (p=0.01) as potential risk factors for non-improvement following heart surgery. Although, elderly patients (age >60 year’s) with greater operative risk have low preoperative quality of life score, but demonstrate an equal improvement in most of the health domains following heart surgery as like as younger study population

    Off pump coronary artery bypass grafting in awake patient

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    This article has no abstract. The first 100 words appear below: A 60-year-old male patient was admitted into the department as a diagnosed case of ischemic heart disease and his coronary angiogram reveals triple vessel disease (80-90% lesion in the mid part of left anterior descending artery; 90% lesion in the distal part of obtuse marginal and 99% stenosis in the distal part of right coronary artery). The patient was suffering from chest pain for last 3 months which aggravated by exertion and radiates along the neck and left arm. The patient was non-diabetic and non-hypertensive

    Coronary atheroma [14 cm] extracted from the right coronary artery during off-pump coronary artery bypass grafting 

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    Coronary endarterectomy is a good option for surgical revascularization in diffusely coronary artery disease. In coronary artery bypass surgery, a diffusely diseased right coronary artery is an obstruction to accomplishing complete myocardial revascularization, subsequently increasing the likelihood of a poor postoperative prognosis. Here, we report a case of extraction of a long segment coronary atheroma (14 cm) from right coronary artery during off-pump coronary artery bypass grafting using closed endarterectomy technique followed by reconstruction with saphenous venous graft

    Ultrasonic Wave Propagation Assessment of Native Cartilage Explants and Hydrogel Scaffolds for Tissue Engineering

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    Non-destructive techniques characterising the mechanical properties of cells, tissues, and biomaterials provide baseline metrics for tissue engineering design. Ultrasonic wave propagation and attenuation has previously demonstrated the dynamics of extracellular matrix synthesis in chondrocyte-seeded hydrogel constructs. In this paper, we describe an ultrasonic method to analyse two of the construct elements used to engineer articular cartilage in real-time, native cartilage explants and an agarose biomaterial. Results indicated a similarity in wave propagation velocity ranges for both longitudinal (1500-1745 m/s) and transverse (350-950 m/s) waveforms. Future work will apply an acoustoelastic analysis to distinguish between the fluid and solid properties including the cell and matrix biokinetics as a validation of previous mathematical models

    Rectangular ZnO porous nano-plate assembly with excellent acetone sensing performance and catalytic activity

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    The controlled synthesis of a hierarchically assembled porous rectangular ZnO plate (2.5-3.5 mm length, 1.5-2.5 mm width and 100-150 nm thickness) from bulk ZnO without using any organic substrates, such as solvents/surfactants/structure-directing agents, is presented. The synthesized ZnO plates are single crystalline with exposed (10 (1) over bar0) facets on the flat surface, porous and formed through the calcination of a hydrozincite Zn-5(CO3)(2)(OH)(6)] intermediate. A gas sensor based on the synthesized porous ZnO architecture exhibited high sensitivity towards acetone even in low concentration (S = 3.4 in 1 ppm acetone) with good selectivity. The ZnO nanostructured material as a heterogeneous catalyst also showed excellent catalytic activity for the synthesis of 5-substituted-1H-tetrazoles (yield = 94%). Both the activities are superior than those of other reported ZnO based acetone sensors and heterogeneous catalysts. We believe that the improved properties of the synthesized ZnO nanostructure is due to the exposed (10 (1) over bar0) facets, and its porous and assembled structure, which provides a reasonably large accessible surface area, and facilitates diffusion and mass transport of gas or substrate molecules
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