“‘Sink or swim’: buoyancy and coping in the cognitive test anxiety – academic performance relationship”

© 2015 Taylor & Francis This study explores the relationship between students’ self-report levels of cognitive test anxiety (worry), academic buoyancy (withstanding and successfully responding to routine school challenges and setbacks), coping processes and their achieved grades in high-stakes national examinations at the end of compulsory schooling. The sample comprised 325 English students in their final year of secondary school preparing for high-stakes examinations. While controlling for prior attainment and gender, higher worry predicted lower examinations scores. This was partially mediated by less use of effective pre-exam coping strategies. Academic buoyancy moderated the indirect relationship such that the indirect negative relationship from worry to examination performance was stronger when academic buoyancy was lower. The paper concludes that providing in-school training in task-focus and orientation and how to withstand academic pressures may help to ameliorate the influence of performance-interfering worries, and potentially enhance performance among students inclined to worry about examinations

Folate-conjugated nanoparticles as a potent therapeutic approach in targeted cancer therapy

The selective and efficient drug delivery to tumor cells can remarkably improve different cancer therapeutic approaches. There are several nanoparticles (NPs) which can act as a potent drug carrier for cancer therapy. However, the specific drug delivery to cancer cells is an important issue which should be considered before designing new NPs for in vivo application. It has been shown that cancer cells over-express folate receptor (FR) in order to improve their growth. As normal cells express a significantly lower levels of FR compared to tumor cells, it seems that folate molecules can be used as potent targeting moieties in different nanocarrier-based therapeutic approaches. Moreover, there is evidence which implies folate-conjugated NPs can selectively deliver anti-tumor drugs into cancer cells both in vitro and in vivo. In this review, we will discuss about the efficiency of different folate-conjugated NPs in cancer therapy. © 2015, International Society of Oncology and BioMarkers (ISOBM)

Dynamic Resource Sharing in 5G with LSA: Criteria-Based Management Framework

Owing to a steadily increasing demand for efficient spectrum utilization as part of the fifth-generation (5G) cellular concept, it becomes crucial to revise the existing radio spectrum management techniques and provide more flexible solutions for the corresponding challenges. A new wave of spectrum policy reforms can thus be envisaged by producing a paradigm shift from static to dynamic orchestration of shared resources. The emerging Licensed Shared Access (LSA) regulatory framework enables flexible spectrum sharing between a limited number of users that access the same frequency bands, while guaranteeing better interference mitigation. In this work, an advanced user satisfaction-aware spectrum management strategy for dynamic LSA management in 5G networks is proposed to balance both the connected user satisfaction and the Mobile Network Operator (MNO) resource utilization. The approach is based on the MNO decision policy that combines both pricing and rejection rules in the implemented processes. Our study offers a classification built over several types of users, different corresponding attributes, and a number of MNO's decision scenarios. Our investigations are built on Criteria-Based Resource Management (CBRM) framework, which has been specifically designed to facilitate dynamic LSA management in 5G mobile networks. To verify the proposed model, the results (spectrum utilization, estimated Secondary User price for the future connection, and user selection methodology in case of user rejection process) are validated numerically as we yield important conclusions on the applicability of our approach, which may offer valuable guidelines for efficient radio spectrum management in highly dynamic and heterogeneous 5G environments. © 2018 Zhaleh Sadreddini et al

Prevalence of Helicobacter pylori and cytotoxin-associated gene A in Iranian patients with non-erosive and erosive reflux disease

Background: The prevalence of Helicobacter pylori (H. pylori) infection and its virulent strain (cytotoxin-associated gene A: CagA) has not been evaluated in patients with gastroesophageal reflux disease (GERD) subgroups (erosive and non-erosive) in Iran. AIMS: This study was conducted to evaluate H. pylori infection and anti-CagA status in GERD. Setting and Design: One hundred fifty-four patients (71 male and 83 female; mean age, 42.6± 15.5 years) were evaluated for symptoms - heartburn and acid regurgitation - compatible with GERD. Materials and Methods: The esophagus was diagnosed endoscopically whether it was with erosion (erosive reflux disease, ERD) or without erosion (non-erosive reflux disease, NERD). Rates of anti-H. pylori and anti-CagA-IgG (immunoglobulin G) antibodies were determined for each subject by ELISA. H. pylori was considered by ELISA if the rapid urease test proved positive. Statistical Analysis: anti-H. pylori and anti-CagA statuses were compared in ERD and NERD patients with and without related IgG antibodies. Mean values and P values were calculated using SPSS (version 12). Results: The overall prevalence of H. pylori infection was 75.3% (116/154). Anti-CagA antibody was found in 60.3% (70/116) of infected patients. The prevalence of H. pylori infection in patients with NERD and ERD was 81.2% (56/69) and 70.6% (60/85), respectively (OR= 0.56; 95% CI [confidence interval]= 0.26-1.20; P= .14). The prevalence of anti-CagA antibody in infected NERD and ERD patients was 58.9% (33/56) and 61.7% (37/60), respectively (OR= 1.16; 95% CI= 0.49-1.70; P= 0.83). Conclusion: The results showed that more than 70% of the patients, either NERD or ERD, acquire H. pylori infection. Anti-CagA antibody is also common in patients with reflux disorders in our community