222 research outputs found

    Smart handoff technique for internet of vehicles communication using dynamic edge-backup node

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    © 2020 The Authors. Published by MDPI. This is an open access article available under a Creative Commons licence. The published version can be accessed at the following link on the publisher’s website: https://doi.org/10.3390/electronics9030524A vehicular adhoc network (VANET) recently emerged in the the Internet of Vehicles (IoV); it involves the computational processing of moving vehicles. Nowadays, IoV has turned into an interesting field of research as vehicles can be equipped with processors, sensors, and communication devices. IoV gives rise to handoff, which involves changing the connection points during the online communication session. This presents a major challenge for which many standardized solutions are recommended. Although there are various proposed techniques and methods to support seamless handover procedure in IoV, there are still some open research issues, such as unavoidable packet loss rate and latency. On the other hand, the emerged concept of edge mobile computing has gained crucial attention by researchers that could help in reducing computational complexities and decreasing communication delay. Hence, this paper specifically studies the handoff challenges in cluster based handoff using new concept of dynamic edge-backup node. The outcomes are evaluated and contrasted with the network mobility method, our proposed technique, and other cluster-based technologies. The results show that coherence in communication during the handoff method can be upgraded, enhanced, and improved utilizing the proposed technique.Published onlin

    Evaluation of Antibiotics Pattern of Extended Spectrum Beta-Lactamase Producing Multi-Drug Resistant Pseudomonas aeruginosa

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    Background: Pseudomonas aeruginosa (Ps. aeruginosa) is considered as an opportunistic pathogen and the leading cause of morbidity and mortality in immunocompromised individuals. Globally, approximately 10-15% of the nosocomial infections are caused by Ps. aeruginosa. The Ps. aeruginosa can acquire resistance against broad-spectrum antibiotics. According to recent studies increased mortality has been observed due to infection with extended-spectrum-beta-lactamase (ESBL) producing Ps. aeruginosa strains. This study was designed to determined antibiogram of ESBL producing multi-drug resistant Ps. aeruginosa in Khyber Pakhtunkhwa.Methods: The clinical confirmed Ps. aeruginosa samples were collected according to the standard protocol, at Khyber Teaching Hospital (KTH), Peshawar. All collected samples were sub- cultured on appropriate culture media. After isolation and identification, the antibiotics susceptibility testing was performed. The detection of ESBL was carried out by the double-disc diffusion method. Carbapenemase-producing bacteria was confirmed by the modified Hodge test. Descriptive analysis was performed for statistical analysis of collected data.Results: A total of one hundred and sixty-two (n=162) Ps. aeruginosa confirmed isolates were collected, in which 59.3% were male and 40.7% were from female patients. The percentages of ESBL and carbapenemase producing Ps. aeruginosa isolates were 5.5% and 23.5%, respectively. The multidrug resistance was observed against 27.2% isolates. Among tested antibiotics highest percentages of resistance was observed against ciprofloxacin (43%) and ceftazidime (39.5%). Conclusion: We observed highest level of drug resistance in Ps. aeruginosa clinical isolates against tested antibiotics and majority of the isolates were Multi-drug resistant (MDR).Keywords: Pseudomonas; Multi-Drug Resistant; Extended Spectrum Beta Lactamases; Antibiotics Susceptibilit

    Comprehensive survey on big data privacy protection

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    In recent years, the ever-mounting problem of Internet phishing has been threatening the secure propagation of sensitive data over the web, thereby resulting in either outright decline of data distribution or inaccurate data distribution from several data providers. Therefore, user privacy has evolved into a critical issue in various data mining operations. User privacy has turned out to be a foremost criterion for allowing the transfer of confidential information. The intense surge in storing the personal data of customers (i.e., big data) has resulted in a new research area, which is referred to as privacy-preserving data mining (PPDM). A key issue of PPDM is how to manipulate data using a specific approach to enable the development of a good data mining model on modified data, thereby meeting a specified privacy need with minimum loss of information for the intended data analysis task. The current review study aims to utilize the tasks of data mining operations without risking the security of individuals’ sensitive information, particularly at the record level. To this end, PPDM techniques are reviewed and classified using various approaches for data modification. Furthermore, a critical comparative analysis is performed for the advantages and drawbacks of PPDM techniques. This review study also elaborates on the existing challenges and unresolved issues in PPDM.Published versio

    Phytotoxic characterization of crude methanolic extract of Periploca aphylla

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    Periploca aphylla is traditionally used in the treatment of various ailments. Phytotoxic activity of crude methanolic extract of P. aphylla was tested on the germination of wheat seeds and on the growth of the germinated seedlings. In both the field and plate studies, the extract showed inhibitory effect on the germination of the growth of root and shoot of the seedlings. The inhibition was found to be dose dependent. The higher concentration of 1000 μg/ml showed maximum inhibitory effect on the growth of root and shoots in the studies of plate as well as on fresh and dry weight of wheat plant. Similarly, the herbicidal activity is also dependent on the concentration of extract. In this study, it was found that inhibitory potential of methanolic extract of P. aphylla increased as 1000 >100 >10 μg/ml.Keywords: Phytotoxic activity, herbicidal activity, germination, plates and field studies, Perifloca aphyll

    Phytotoxic, Antibacterial and Haemagglutination activities of the aerial parts of Myrsine africana L.

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    The crude methanolic extract and various fractions derived from the aerial parts of Myrsine africana were screened in vitro for possible phytotoxic, antibacterial and haemagglutination activities. Moderate phytotoxic activity (31.25 %) was observed against Lemna minor L at 1000 μg/ml by chloroform fraction (CHCl3). The crude methanolic extract and CHCl3 fraction showed good antibacterial activity against Klebsiella pneumoniae (MIC50 = 2.45 and 2.1 mg/ml respectively). The crude methanolic extract and other fractions showed moderate activity against tested bacterial strains. The CHCl3 and aqueous fractions showed no activity against Escherichia coli. Similarly, the ethyl acetate (EtOAc) and butanol (BuOH) fractions were found to be non active against Bacillus pumilus and Enterobacter aerogenes, respectively. Moderate haemagglutination activity was observed against human red blood cells (RBCs) of blood group AB- by crude methanolic extract and CHCl3 fraction and against AB+ by aqueous fraction, respectively. The plant specie can be a source of antibacterial agent(s) and phytolectins.Keywords: Myrsine africana, phytotoxicity, haemagglutination, antibacterial and MIC5

    A case of orbital apex syndrome in a patient with malignant otitis externa

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    Abstract A rare case of skull base infection with a rapid clinical course leading to visual loss and eventually death in a poorly-controlled diabetic patient is presented. A 37-year-old woman presented with a history of visual loss and painful protrusion of the right eye for the preceding 3 days.This was accompanied by vertigo and right-side facial weakness. The patient had perception of light in her right eye and 20/25 (presenting visual acuity) in the fellow eye, accompanied by right-side proptosis, total ophthalmoplegia, optic disc pallor and central retinal artery occlusion. Magnetic resonance imaging showed the presence of oedema with soft-tissue thickening in the right external auditory canal along with evidence of fluid within the middle ear cavity and mastoid air cells on the right side. A diagnosis of Orbital Apex Syndrome was made and treatment initiated

    Potential application of Conyza canadensis (L) Cronquist in the management of diabetes: In vitro and in vivo evaluation

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    Purpose: To investigate the antihyperglycemic activity of Conyza canadensis via α-glucosidase inhibition in alloxan-induced diabetic mice.Methods: In vitro antidiabetic activity was investigated using α-glucosidase inhibition assay with acarbose (62.5, 125, 500 and 1000 μg/ml) as the standard drug. Conyza canadensis crude extract (Cc.Cr) in doses of 10, 30, 100 and 300 mg/kg were administered daily as a single dose to alloxaninduced (200 mg/kg) diabetic mice (Balb/c), and its effect on fasting blood glucose levels and body weight were evaluated for 15 consecutive days; oral glucose tolerance test was conducted. Metformin (500 mg/kg) was used as a standard antidiabetic drug for comparison. Acute toxicity of Cc.Cr was also evaluated at doses of 3 and 5 g/kg.Results: Conyza canadensis crude extract (Cc.Cr) exhibited strong enzyme inhibition at concentrations (μg/ml) of 1000 (74.78 ± 0.92), 500 (65.11 ± 0.07), 250 (57.55 ± 0.41), 125 (51.55 ± 0.67) and 62.5 ( 44.00 ± 0.57), with a median inhibitory concentration (IC50) of 107 μg/ml. Cc.Cr at all test doses (10 - 300 mg / kg) reduced fasting blood glucose levels in alloxan (200 mg/kg) - induced diabetic mice on days 5, 10 and 15 compared to the diabetic control group (p < 0. 001). These effects were similar to those caused by the standard antidiabetic drug, metformin. Cc.Cr at all test doses also increased body weight of treated animals. The extract (300 mg/kg) significantly improved tolerance of oral glucose overload in mice, like metformin. The extract did not cause any mortality up to the maximum dose of 5 g/kg.Conclusion: The results reveal that Conyza canadensis possesses potent secondary metabolites which can cause inhibition of α-glucosidase. Moreover, the plant extract has the ability to reduce blood glucose level in diabetic animals and significantly improves oral glucose overload tolerance.Keywords: Conyza canadensis, α-Glucosidase, Blood glucose, Alloxan, Diabetes, Glucose toleranc

    An Investigation of the Major Wheat Weeds in Different Zones of Dera Ismail Khan

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    On account of huge yield losses, weed infestation is a serious threat in wheat crops throughout the country. A comprehensive survey to find out the major weeds in wheat in Dera Ismail Khan was carried out during the crop season of 2012-13. Wheat fields at seed farms of Rakhmanghan, RakhZandani, Rata Kulachi and adjacent farmer’s fields to each seed farm were investigated. Data was collected at the peak growth stage of weeds and the quadratic method was used to record relative density (RD), relative frequency (RF), relative crowding coefficient (RCC) and importance value index (IVI). The results revealed that the major and most problematic weed of wheat at all the locations was Avena fatua (wild oat) on account of having maximum IVI at Rakh Manghan (78.51 & 77.44), Rata Kulachi (77.82 & 77.54) and Rakh Zandani (77.51 & 77.53) seed Farms and Farmer’s fields respectively. Rumex dentatus (dock) and Convolvulus arvensis (Lehli) were the second and third abundantly occurring weeds at almost all the seed farms and farmer fields on account of having the second and third highest IVI values at all the locations. Therefore Avena fatua (wildoat), Rumex dentatus (dock) and Convolvulus arvensis (lehli) seed were collected to find out the yield losses through further experimentation
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