Empirical Analyses of the Relationship between Trade and Budget Deficit of FYR of Macedonia

The purpose of this article is to analyze the evidence of twin deficits hypothesis by empirically examining the relationship between trade deficit and budget deficit for the case of FYR of Macedonia. The study employs a vector autoregression (VAR) model as well as a Granger causality test in order to investigate the causal relationship between trade and budget deficit variables using quarterly data for the time period 1998Q1–2017Q4. The econometric results of VAR model disclose that there exists a short term relationship between these two variables, implying that higher trade deficits are associated with higher fiscal deficits. Moreover, the causality test shows a unidirectional relationship, revealing that trade deficit causes budget deficit, whereas budget deficit doesn't cause trade deficit.     Keywords: trade deficit, budget deficit, causality analysi

Optimal design of nanoplasmonic materials using genetic algorithms as a multi-parameter optimization tool

An optimal control approach based on multiple parameter genetic algorithms is applied to the design of plasmonic nanoconstructs with pre-determined optical properties and functionalities. We first develop nanoscale metallic lenses that focus an incident plane wave onto a pre-specified, spatially confined spot. Our results illustrate the role of symmetry breaking and unravel the principles that favor dimeric constructs for optimal light localization. Next we design a periodic array of silver particles to modify the polarization of an incident, linearly-polarized plane wave in a desired fashion while localizing the light in space. The results provide insight into the structural features that determine the birefringence properties of metal nanoparticles and their arrays. Of the variety of potential applications that may be envisioned, we note the design of nanoscale light sources with controllable coherence and polarization properties that could serve for coherent control of molecular or electronic dynamics in the nanoscale.Comment: 13 pages, 6 figures. submitted to J. Chem. Phy

Optical properties of metal nanoparticles with no center of inversion symmetry: observation of volume plasmons

We present theoretical and experimental studies of the optical response of L-shaped silver nanoparticles. The scattering spectrum exhibits several plasmon resonances that depend sensitively on the polarization of the incident electromagnetic field. The physical origin of the resonances is traced to different plasmon phenomena. In particular, a high energy band with unusual properties is interpreted in terms of volume plasmon oscillations arising from the asymmetry of a nanoparticle.Comment: 14 pages, 5 figures. Physical Review B, 2007, accepte

Three-Dimensional FDTD Simulation of Biomaterial Exposure to Electromagnetic Nanopulses

Ultra-wideband (UWB) electromagnetic pulses of nanosecond duration, or nanopulses, have been recently approved by the Federal Communications Commission for a number of various applications. They are also being explored for applications in biotechnology and medicine. The simulation of the propagation of a nanopulse through biological matter, previously performed using a two-dimensional finite difference-time domain method (FDTD), has been extended here into a full three-dimensional computation. To account for the UWB frequency range, a geometrical resolution of the exposed sample was $0.25 mm$, and the dielectric properties of biological matter were accurately described in terms of the Debye model. The results obtained from three-dimensional computation support the previously obtained results: the electromagnetic field inside a biological tissue depends on the incident pulse rise time and width, with increased importance of the rise time as the conductivity increases; no thermal effects are possible for the low pulse repetition rates, supported by recent experiments. New results show that the dielectric sample exposed to nanopulses behaves as a dielectric resonator. For a sample in a cuvette, we obtained the dominant resonant frequency and the $Q$-factor of the resonator.Comment: 15 pages, 8 figure

Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism

Limiting dysfunctional neutrophilic inflammation while preserving effective immunity requires a better understanding of the processes that dictate neutrophil function in the tissues. Quantitative mass-spectrometry identified how inflammatory murine neutrophils regulated expression of cell surface receptors, signal transduction networks, and metabolic machinery to shape neutrophil phenotypes in response to hypoxia. Through the tracing of labeled amino acids into metabolic enzymes, proinflammatory mediators, and granule proteins, we demonstrated that ongoing protein synthesis shapes the neutrophil proteome. To maintain energy supplies in the tissues, neutrophils consumed extracellular proteins to fuel central carbon metabolism. The physiological stresses of hypoxia and hypoglycemia, characteristic of inflamed tissues, promoted this extracellular protein scavenging with activation of the lysosomal compartment, further driving exploitation of the protein-rich inflammatory milieu. This study provides a comprehensive map of neutrophil proteomes, analysis of which has led to the identification of active catabolic and anabolic pathways that enable neutrophils to sustain synthetic and effector functions in the tissues

An exploration of the factors influencing career choice in mental health

Aims and objectives: To identify the factors that are associated with considering a career in mental health. Background: The mental health specialty is facing a recruitment crisis in the United Kingdom but there is limited evidence about which factors encourage and discourage people from considering a career in mental health. Design: Quantitative, observational, online survey using a multiple ordinal logistic regression model to identify if there were any significant predictors of the extent to which participants would consider a career in mental health. The design and write up of the study were guided by the STROBE checklist. Method: We gathered the views of 231 participants (female = 188, 81.7%) aged between 16–65 (mean = 22.7, SD = 8.9), using an online survey, the majority of whom were studying on, or graduates of, psychology/social studies degrees. Information was gathered about the extent to which a range of factors influenced consideration of a career in mental health. Results: The majority (71.2%) of participants reported that they would definitely or probably consider undertaking a career in mental health, and over half (51.4%) would consider a career as a mental health nurse. The ability to help others and receiving appropriate training required for the role were important career choice factors. Being female, having a mental health condition and greater knowledge of mental health were associated with a significantly greater likelihood of considering a career in mental health, while having had experience of working with people with mental health difficulties was significantly negatively associated. Conclusions: Students and graduates of psychology and social studies degrees appear to be a large, untapped recruitment pool for mental health services. Relevance to clinical practice: The results can inform more targeted recruitment strategies and development of suitable career pathways for those interested in a career in mental health