896 research outputs found
Caracterização de adubos orgânicos por espectroscopia de ressonância paramagnética eletrônica.
Utilização da Espectroscopia de Ressonância Paramagnética Eletrônica para Avaliar a Presença de Impurezas em Adubos Orgânicos.
bitstream/CNPDIA/10476/1/CT67_2005.pd
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Effectiveness of Ledipasvir/Sofosbuvir with/without Ribavarin in Liver Transplant Recipients with Hepatitis C.
Background and Aims: Recurrent infection of hepatitis C virus (HCV) in liver transplant (LT) recipients is universal and associated with significant morbidity and mortality. Methods: We retrospectively evaluated the safety and efficacy of ledipasvir/sofosbuvir with and without ribavirin in LT recipients with recurrent genotype 1 hepatitis C. Results: Eighty-five LT recipients were treated for recurrent HCV with ledipasvir/sofosbuvirwith and without ribavirin for 12 or 24 weeks. The mean (± standard deviation [SD]) time from LT to treatment initiation was 68 (±71) months. The mean (± SD) age of the cohort was 63 (±8.6) years old. Most recipients were male (70%). Baseline alanine transaminase, total bilirubin, and HCV ribonucleic acid (RNA) values (± SD) were 76.8 (±126) mg/dL, 0.8 (±1.3) U/L, and 8,010,421.9 (±12,420,985) IU/mL, respectively. Five of 43 recipients who were treated with ribavirin required drug cessation due to side effects, with 4 of those being anemia complications. No recipient discontinued the ledipasvir/sofosbuvir. Eighty-one percent of recipients had undetectable viral levels at 4 weeks after starting therapy, and all recipients had complete viral suppression at the end of therapy. The sustained viral response at 12 weeks after completion of therapy was 94%. Conclusion : Ledipasvir and sofosbuvir with and without ribavirin therapy is an effective and well-tolerated interferon-free treatment for recurrent HCV infection after LT. Anemia is not uncommon in LT recipients receiving ribavirin
Caracterização de solos orgânicos do Estado do Rio de Janeiro: propriedades fÃsicas e morfológicas como subsÃdios à classificação.
bitstream/item/62880/1/CNPS-PESQ.-AND.-4-99.pd
Low-threshold analysis of CDMS shallow-site data
Data taken during the final shallow-site run of the first tower of the
Cryogenic Dark Matter Search (CDMS II) detectors have been reanalyzed with
improved sensitivity to small energy depositions. Four ~224 g germanium and two
~105 g silicon detectors were operated at the Stanford Underground Facility
(SUF) between December 2001 and June 2002, yielding 118 live days of raw
exposure. Three of the germanium and both silicon detectors were analyzed with
a new low-threshold technique, making it possible to lower the germanium and
silicon analysis thresholds down to the actual trigger thresholds of ~1 keV and
~2 keV, respectively. Limits on the spin-independent cross section for weakly
interacting massive particles (WIMPs) to elastically scatter from nuclei based
on these data exclude interesting parameter space for WIMPs with masses below 9
GeV/c^2. Under standard halo assumptions, these data partially exclude
parameter space favored by interpretations of the DAMA/LIBRA and CoGeNT
experiments' data as WIMP signals, and exclude new parameter space for WIMP
masses between 3 GeV/c^2 and 4 GeV/c^2.Comment: 18 pages, 12 figures, 5 table
Search for inelastic dark matter with the CDMS II experiment
Results are presented from a reanalysis of the entire five-tower data set
acquired with the Cryogenic Dark Matter Search (CDMS II) experiment at the
Soudan Underground Laboratory, with an exposure of 969 kg-days. The analysis
window was extended to a recoil energy of 150 keV, and an improved
surface-event background-rejection cut was defined to increase the sensitivity
of the experiment to the inelastic dark matter (iDM) model. Three dark matter
candidates were found between 25 keV and 150 keV. The probability to observe
three or more background events in this energy range is 11%. Because of the
occurrence of these events the constraints on the iDM parameter space are
slightly less stringent than those from our previous analysis, which used an
energy window of 10-100 keV.Comment: 10 pages, 10 figures, minor changes to match published version,
conclusion unchange
Estudo comparativo de métodos de determinação do teor de matéria orgânica em solos orgânicos do Estado do Rio de Janeiro.
bitstream/item/62879/1/CNPS-PESQ.-AND.-3-99.pd
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