Infected pancreatic necrosis: outcomes and clinical predictors of mortality. A post hoc analysis of the MANCTRA-1 international study

: The identification of high-risk patients in the early stages of infected pancreatic necrosis (IPN) is critical, because it could help the clinicians to adopt more effective management strategies. We conducted a post hoc analysis of the MANCTRA-1 international study to assess the association between clinical risk factors and mortality among adult patients with IPN. Univariable and multivariable logistic regression models were used to identify prognostic factors of mortality. We identified 247 consecutive patients with IPN hospitalised between January 2019 and December 2020. History of uncontrolled arterial hypertension (p = 0.032; 95% CI 1.135-15.882; aOR 4.245), qSOFA (p = 0.005; 95% CI 1.359-5.879; aOR 2.828), renal failure (p = 0.022; 95% CI 1.138-5.442; aOR 2.489), and haemodynamic failure (p = 0.018; 95% CI 1.184-5.978; aOR 2.661), were identified as independent predictors of mortality in IPN patients. Cholangitis (p = 0.003; 95% CI 1.598-9.930; aOR 3.983), abdominal compartment syndrome (p = 0.032; 95% CI 1.090-6.967; aOR 2.735), and gastrointestinal/intra-abdominal bleeding (p = 0.009; 95% CI 1.286-5.712; aOR 2.710) were independently associated with the risk of mortality. Upfront open surgical necrosectomy was strongly associated with the risk of mortality (p < 0.001; 95% CI 1.912-7.442; aOR 3.772), whereas endoscopic drainage of pancreatic necrosis (p = 0.018; 95% CI 0.138-0.834; aOR 0.339) and enteral nutrition (p = 0.003; 95% CI 0.143-0.716; aOR 0.320) were found as protective factors. Organ failure, acute cholangitis, and upfront open surgical necrosectomy were the most significant predictors of mortality. Our study confirmed that, even in a subgroup of particularly ill patients such as those with IPN, upfront open surgery should be avoided as much as possible. Study protocol registered in ClinicalTrials.Gov (I.D. Number NCT04747990)

An embedding technique to determine ττ backgrounds in proton-proton collision data

The Secretaría de Estado de Investigación, Desarrollo e Innovación, Programa ConsoliderIngenio 2010, Plan Estatal de Investigación Científica y Técnica y de Innovación 2013–2016, Plan de Ciencia, Tecnología e Innovación 2013–2017 del Principado de Asturias, and Fondo Europeo de Desarrollo Regional, Spain. Individuals have received support from the Marie-Curie program and the European Research Council and Horizon 2020 Grant, contract No. 675440 (European Union); the Programa de Excelencia María de Maeztu, and the Programa Severo Ochoa del Principado de Asturias (...)Sirunyan, A.M., Tumasyan, A., Adam, W., Ambrogi, F., Asilar, E., Bergauer, T., Brandstetter, J., Dragicevic, M., Erö, J., Escalante Del Valle, A., Flechl, M., Frühwirth, R., Ghete, V.M., Hrubec, J., Jeitler, M., Krammer, N., Krätschmer, I., Liko, D., Madlener, T., Mikulec, I., Rad, N., Rohringer, H., Schieck, J., Schöfbeck, R., Spanring, M., Spitzbart, D., Waltenberger, W., Wittmann, J., Wulz, C.-E., Zarucki, M., Chekhovsky, V., Mossolov, V., Suarez Gonzalez, J., De Wolf, E.A., Di Croce, D., Janssen, X., Lauwers, J., Lelek, A., Pieters, M., Van Haevermaet, H., Van Mechelen, P., Van Remortel, N., Blekman, F., D'Hondt, J., De Clercq, J., Deroover, K., Flouris, G., Lontkovskyi, D., Lowette, S., Marchesini, I., Moortgat, S., Moreels, L., Python, Q., Skovpen, K., Tavernier, S., Van Doninck, W., Van Mulders, P., Van Parijs, I., Beghin, D., Bilin, B., Brun, H., Clerbaux, B., De Lentdecker, G., Delannoy, H., Dorney, B., Fasanella, G., Favart, L., Grebenyuk, A., Kalsi, A.K., Luetic, J., Popov, A., Postiau, N., Starling, E., Thomas, L., Vander Velde, C., Vanlaer, P., Vannerom, D., Wang, Q., Cornelis, T., Dobur, D., Fagot, A., Gul, M., Khvastunov, I., Roskas, C., Trocino, D., Tytgat, M., Verbeke, W., Vermassen, B., Vit, M., Zaganidis, N., Bakhshiansohi, H., Bondu, O., Bruno, G., Caputo, C., David, P., Delaere, C., Delcourt, M., Giammanco, A., Krintiras, G., Lemaitre, V., Magitteri, A., Piotrzkowski, K., Saggio, A., Vidal Marono, M., Vischia, P., Zobec, J., Alves, F.L., Alves, G.A., Correia Silva, G., Hensel, C., Moraes, A., Pol, M.E., Rebello Teles, P., Belchior Batista Das Chagas, E., Carvalho, W., Chinellato, J., Coelho, E., Da Costa, E.M., Da Silveira, G.G., De Jesus Damiao, D., De Oliveira Martins, C., Fonseca De Souza, S., Huertas Guativa, L.M., Malbouisson, H., Matos Figueiredo, D., Melo De Almeida, M., Mora Herrera, C., Mundim, L., Nogima, H., Prado Da Silva, W.L., Sanchez Rosas, L.J., Santoro, A., Sznajder, A., Thiel, M., Tonelli Manganote, E.J., Torres Da Silva De Araujo, F., Vilela Pereira, A., Ahuja, S., Bernardes, C.A., Calligaris, L., Fernandez Perez Tomei, T.R., Gregores, E.M., Mercadante, P.G., Novaes, S.F., Padula, S.S., Aleksandrov, A., Hadjiiska, R., Iaydjiev, P., Marinov, A., Misheva, M., Rodozov, M., Shopova, M., Sultanov, G., Dimitrov, A., Litov, L., Pavlov, B., Petkov, P., Fang, W., Gao, X., Yuan, L., Ahmad, M., Bian, J.G., Chen, G.M., Chen, H.S., Chen, M., Chen, Y., Jiang, C.H., Leggat, D., Liao, H., Liu, Z., Shaheen, S.M., Spiezia, A., Tao, J., Yazgan, E., Zhang, H., Zhang, S., Zhao, J., Ban, Y., Chen, G., Levin, A., Li, J., Li, L., Li, Q., Mao, Y., Qian, S.J., Wang, D., Wang, Y., Avila, C., Cabrera, A., Carrillo Montoya, C.A., Chaparro Sierra, L.F., Florez, C., González Hernández, C.F., Segura Delgado, M.A., Godinovic, N., Lelas, D., Puljak, I., Sculac, T., Antunovic, Z., Kovac, M., Brigljevic, V., Ferencek, D., Kadija, K., Mesic, B., Roguljic, M., Starodumov, A., Susa, T., Ather, M.W., Attikis, A., Kolosova, M., Mavromanolakis, G., Mousa, J., Nicolaou, C., Ptochos, F., Razis, P.A., Rykaczewski, H., Finger, M., Finger, M., Jr., Ayala, E., Carrera Jarrin, E., Ellithi Kamel, A., Mahmoud, M.A., Salama, E., Bhowmik, S., Carvalho Antunes Deoliveira, A., Dewanjee, R.K., Ehataht, K., Kadastik, M., Raidal, M., Veelken, C., Eerola, P., Kirschenmann, H., Pekkanen, J., Voutilainen, M., Havukainen, J., Heikkilä, J.K., Järvinen, T., Karimäki, V., Kinnunen, R., Lampén, T., Lassila-Perini, K., Laurila, S., Lehti, S., Lindén, T., Luukka, P., Mäenpää, T., Siikonen, H., Tuominen, E., Tuominiemi, J., Tuuva, T., Besancon, M., Couderc, F., Dejardin, M., Denegri, D., Faure, J.L., Ferri, F., Ganjour, S., Givernaud, A., Gras, P., Hamel De Monchenault, G., Jarry, P., Leloup, C., Locci, E., Malcles, J., Negro, G., Rander, J., Rosowsky, A., Sahin, M.Ö., Titov, M., Abdulsalam, A., Amendola, C., Antropov, I., Beaudette, F., Busson, P., Charlot, C., Diab, B., Granier De Cassagnac, R., Kucher, I., Lobanov, A., Martin Blanco, J., Martin Perez, C., Nguyen, M., Ochando, C., Ortona, G., Paganini, P., Rembser, J., Salerno, R., Sauvan, J.B., Sirois, Y., Stahl Leiton, A.G., Zabi, A., Zghiche, A., Agram, J.-L., Andrea, J., Bloch, D., Bourgatte, G., Brom, J.-M., Chabert, E.C., Cherepanov, V., Collard, C., Conte, E., Fontaine, J.-C., Gelé, D., Goerlach, U., Jansová, M., Le Bihan, A.-C., Tonon, N., Van Hove, P., Gadrat, S., Beauceron, S., Bernet, C., Boudoul, G., Chanon, N., Chierici, R., Contardo, D., Depasse, P., El Mamouni, H., Fay, J., Gascon, S., Gouzevitch, M., Grenier, G., Ille, B., Lagarde, F., Laktineh, I.B., Lattaud, H., Lethuillier, M., Mirabito, L., Perries, S., Sordini, V., Touquet, G., Vander Donckt, M., Viret, S., Khvedelidze, A., Tsamalaidze, Z., Autermann, C., Feld, L., Kiesel, M.K., Klein, K., Lipinski, M., Preuten, M., Rauch, M.P., Schomakers, C., Schulz, J., Teroerde, M., Wittmer, B., Albert, A., Erdmann, M., Erdweg, S., Esch, T., Fischer, R., Ghosh, S., Hebbeker, T., Heidemann, C., Hoepfner, K., Keller, H., Mastrolorenzo, L., Merschmeyer, M., Meyer, A., Millet, P., Mukherjee, S., Novak, A., Pook, T., Pozdnyakov, A., Radziej, M., Reithler, H., Rieger, M., Schmidt, A., Teyssier, D., Thüer, S., Flügge, G., Hlushchenko, O., Kress, T., Müller, T., Nehrkorn, A., Nowack, A., Pistone, C., Pooth, O., Roy, D., Sert, H., Stahl, A., Aldaya Martin, M., Arndt, T., Asawatangtrakuldee, C., Babounikau, I., Beernaert, K., Behnke, O., Behrens, U., Bermúdez Martínez, A., Bertsche, D., Bin Anuar, A.A., Borras, K., Botta, V., Campbell, A., Connor, P., Contreras-Campana, C., Danilov, V., De Wit, A., Defranchis, M.M., Diez Pardos, C., Domínguez Damiani, D., Eckerlin, G., Eichhorn, T., Elwood, A., Eren, E., Gallo, E., Geiser, A., Grados Luyando, J.M., Grohsjean, A., Guthoff, M., Haranko, M., Harb, A., Jung, H., Kasemann, M., Keaveney, J., Kleinwort, C., Knolle, J., Krücker, D., Lange, W., Lenz, T., Leonard, J., Lipka, K., Lohmann, W., Mankel, R., Melzer-Pellmann, I.-A., Meyer, A.B., Meyer, M., Missiroli, M., Mittag, G., Mnich, J., Myronenko, V., Pflitsch, S.K., Pitzl, D., Raspereza, A., Saibel, A., Savitskyi, M., Saxena, P., Schütze, P., Schwanenberger, C., Shevchenko, R., Singh, A., Tholen, H., Turkot, O., Vagnerini, A., Van De Klundert, M., Van Onsem, G.P., Walsh, R., Wen, Y., Wichmann, K., Wissing, C., Zenaiev, O., Aggleton, R., Bein, S., Benato, L., Benecke, A., Blobel, V., Dreyer, T., Ebrahimi, A., Garutti, E., Gonzalez, D., Gunnellini, P., Haller, J., Hinzmann, A., Karavdina, A., Kasieczka, G., Klanner, R., Kogler, R., Kovalchuk, N., Kurz, S., Kutzner, V., Lange, J., Marconi, D., Multhaup, J., Niedziela, M., Niemeyer, C.E.N., Nowatschin, D., Perieanu, A., Reimers, A., Rieger, O., Scharf, C., Schleper, P., Schumann, S., Schwandt, J., Sonneveld, J., Stadie, H., Steinbrück, G., Stober, F.M., Stöver, M., Vormwald, B., Zoi, I., Akbiyik, M., Barth, C., Baselga, M., Baur, S., Bechtel, J., Brommer, S., Butz, E., Caspart, R., Chwalek, T., Colombo, F., De Boer, W., Dierlamm, A., El Morabit, K., Faltermann, N., Freund, B., Giffels, M., Gottmann, A., Harrendorf, M.A., Hartmann, F., Heindl, S.M., Husemann, U., Katkov, I., Kudella, S., Mitra, S., Mozer, M.U., Müller, Th., Musich, M., Plagge, M., Quast, G., Rabbertz, K., Schröder, M., Shvetsov, I., Simonis, H.J., Ulrich, R., Wayand, S., Weber, M., Weiler, T., Wöhrmann, C., Wolf, R., Anagnostou, G., Daskalakis, G., Geralis, T., Kyriakis, A., Loukas, D., Paspalaki, G., Agapitos, A., Karathanasis, G., Kontaxakis, P., Panagiotou, A., Papavergou, I., Saoulidou, N., Vellidis, K., Bakas, G., Kousouris, K., Papakrivopoulos, I., Tsipolitis, G., Evangelou, I., Foudas, C., Gianneios, P., Katsoulis, P., Kokkas, P., Mallios, S., Manitara, K., Manthos, N., Papadopoulos, I., Paradas, E., Strologas, J., Triantis, F.A., Tsitsonis, D., Bartók, M., Csanad, M., Filipovic, N., Major, P., Mandal, K., Mehta, A., Nagy, M.I., Pasztor, G., Surányi, O., Veres, G.I., Bencze, G., Hajdu, C., Horvath, D., Hunyadi, Á., Sikler, F., Vámi, T.Á., Veszpremi, V., Vesztergombi, G., Beni, N., Czellar, S., Karancsi, J., Makovec, A., Molnar, J., Szillasi, Z., Raics, P., Trocsanyi, Z.L., Ujvari, B., Choudhury, S., Komaragiri, J.R., Tiwari, P.C., Bahinipati, S., Kar, C., Mal, P., Nayak, A., Roy Chowdhury, S., Sahoo, D.K., Swain, S.K., Bansal, S., Beri, S.B., Bhatnagar, V., Chauhan, S., Chawla, R., Dhingra, N., Gupta, R., Kaur, A., Kaur, M., Kaur, S., Kumari, P., Lohan, M., Meena, M., Sandeep, K., Sharma, S., Singh, J.B., Virdi, A.K., Walia, G., Bhardwaj, A., Choudhary, B.C., Garg, R.B., Gola, M., Keshri, S., Kumar, A., Malhotra, S., Naimuddin, M., Priyanka, P., Ranjan, K., Shah, A., Sharma, R., Bhardwaj, R., Bharti, M., Bhattacharya, R., Bhattacharya, S., Bhawandeep, U., Bhowmik, D., 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Ince, M., Lezki, S., Maggi, G., Maggi, M., Miniello, G., My, S., Nuzzo, S., Pompili, A., Pugliese, G., Radogna, R., Ranieri, A., Selvaggi, G., Sharma, A., Silvestris, L., Venditti, R., Verwilligen, P., Abbiendi, G., Battilana, C., Bonacorsi, D., Borgonovi, L., Braibant-Giacomelli, S., Campanini, R., Capiluppi, P., Castro, A., Cavallo, F.R., Chhibra, S.S., Codispoti, G., Cuffiani, M., Dallavalle, G.M., Fabbri, F., Fanfani, A., Fontanesi, E., Giacomelli, P., Grandi, C., Guiducci, L., Iemmi, F., Lo Meo, S., Marcellini, S., Masetti, G., Montanari, A., Navarria, F.L., Perrotta, A., Primavera, F., Rossi, A.M., Rovelli, T., Siroli, G.P., Tosi, N., Albergo, S., Di Mattia, A., Potenza, R., Tricomi, A., Tuve, C., Barbagli, G., Chatterjee, K., Ciulli, V., Civinini, C., D'Alessandro, R., Focardi, E., Latino, G., Lenzi, P., Meschini, M., Paoletti, S., Russo, L., Sguazzoni, G., Strom, D., Viliani, L., Benussi, L., Bianco, S., Fabbri, F., Piccolo, D., Ferro, F., Mulargia, R., Robutti, E., Tosi, S., 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E., Monteno, M., Obertino, M.M., Pacher, L., Pastrone, N., Pelliccioni, M., Pinna Angioni, G.L., Romero, A., Ruspa, M., Sacchi, R., Salvatico, R., Shchelina, K., Sola, V., Solano, A., Soldi, D., Staiano, A., Belforte, S., Candelise, V., Casarsa, M., Cossutti, F., Da Rold, A., Della Ricca, G., Vazzoler, F., Zanetti, A., Kim, D.H., Kim, G.N., Kim, M.S., Lee, J., Lee, S.W., Moon, C.S., Oh, Y.D., Pak, S.I., Sekmen, S., Son, D.C., Yang, Y.C., Kim, H., Moon, D.H., Oh, G., Francois, B., Goh, J., Kim, T.J., Cho, S., Choi, S., Go, Y., Gyun, D., Ha, S., Hong, B., Jo, Y., Lee, K., Lee, K.S., Lee, S., Lim, J., Park, S.K., Roh, Y., Kim, H.S., Almond, J., Kim, J., Kim, J.S., Lee, H., Lee, K., Lee, S., Nam, K., Oh, S.B., Radburn-Smith, B.C., Seo, S.H., Yang, U.K., Yoo, H.D., Yu, G.B., Jeon, D., Kim, H., Kim, J.H., Lee, J.S.H., Park, I.C., Choi, Y., Hwang, C., Lee, J., Yu, I., Veckalns, V., Dudenas, V., Juodagalvis, A., Vaitkus, J., Ibrahim, Z.A., Md Ali, M.A.B., Mohamad Idris, F., Wan Abdullah, W.A.T., Yusli, M.N., Zolkapli, Z., Benitez, J.F., Castaneda Hernandez, A., Murillo Quijada, J.A., Castilla-Valdez, H., De La Cruz-Burelo, E., Duran-Osuna, M.C., Heredia-De La Cruz, I., Lopez-Fernandez, R., Mejia Guisao, J., Rabadan-Trejo, R.I., Ramirez-Sanchez, G., Reyes-Almanza, R., Sanchez-Hernandez, A., Carrillo Moreno, S., Oropeza Barrera, C., Ramirez-Garcia, M., Vazquez Valencia, F., Eysermans, J., Pedraza, I., Salazar Ibarguen, H.A., Uribe Estrada, C., Morelos Pineda, A., Krofcheck, D., Bheesette, S., Butler, P.H., Ahmad, A., Ahmad, M., Asghar, M.I., Hassan, Q., Hoorani, H.R., Khan, W.A., Shah, M.A., Shoaib, M., Waqas, M., Bialkowska, H., Bluj, M., Boimska, B., Frueboes, T., Górski, M., Kazana, M., Szleper, M., Traczyk, P., Zalewski, P., Bunkowski, K., Byszuk, A., Doroba, K., Kalinowski, A., Konecki, M., Krolikowski, J., Misiura, M., Olszewski, M., Pyskir, A., Walczak, M., Araujo, M., Bargassa, P., Beirão Da Cruz E Silva, C., Di Francesco, A., Faccioli, P., Galinhas, B., 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Searches for pair production of charginos and top squarks in final states with two oppositely charged leptons in proton-proton collisions at vs=13 TeV

SEIDI, CPAN, PCTI and FEDER (Spain); Individuals have received support from the Marie-Curie program and the European Research Council and Horizon 2020 Grant, contract No. 675440 (European Union); the Programa Severo Ochoa del Principado de AsturiasSirunyan, A.M., Tumasyan, A., Adam, W., Ambrogi, F., Asilar, E., Bergauer, T., Brandstetter, J., Dragicevic, M., Erö, J., Escalante Del Valle, A., Flechl, M., Frühwirth, R., Ghete, V.M., Hrubec, J., Jeitler, M., Krammer, N., Krätschmer, I., Liko, D., Madlener, T., Mikulec, I., Rad, N., Rohringer, H., Schieck, J., Schöfbeck, R., Spanring, M., Spitzbart, D., Taurok, A., Waltenberger, W., Wittmann, J., Wulz, C.-E., Zarucki, M., Chekhovsky, V., Mossolov, V., Suarez Gonzalez, J., De Wolf, E.A., Di Croce, D., Janssen, X., Lauwers, J., Pieters, M., Van De Klundert, M., Van Haevermaet, H., Van Mechelen, P., Van Remortel, N., Abu Zeid, S., Blekman, F., D’Hondt, J., De Bruyn, I., De Clercq, J., Deroover, K., Flouris, G., Lontkovskyi, D., Lowette, S., 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Sguazzoni, G., Strom, D., Viliani, L., Benussi, L., Bianco, S., Fabbri, F., Piccolo, D., Ferro, F., Ravera, F., Robutti, E., Tosi, S., Benaglia, A., Beschi, A., Brianza, L., Brivio, F., Ciriolo, V., Di Guida, S., Dinardo, M.E., Fiorendi, S., Gennai, S., Ghezzi, A., Govoni, P., Malberti, M., Malvezzi, S., Massironi, A., Menasce, D., Moroni, L., Paganoni, M., Pedrini, D., Ragazzi, S., Tabarelli de Fatis, T., Zuolo, D., Buontempo, S., Cavallo, N., Di Crescenzo, A., Fabozzi, F., Fienga, F., Galati, G., Iorio, A.O.M., Khan, W.A., Lista, L., Meola, S., Paolucci, P., Sciacca, C., Voevodina, E., Azzi, P., Bacchetta, N., Bisello, D., Boletti, A., Bragagnolo, A., Carlin, R., Checchia, P., Dall’Osso, M., De Castro Manzano, P., Dorigo, T., Dosselli, U., Gasparini, F., Gasparini, U., Gozzelino, A., Lacaprara, S., Lujan, P., Margoni, M., Meneguzzo, A.T., Pazzini, J., Ronchese, P., Rossin, R., Simonetto, F., Tiko, A., Torassa, E., Zanetti, M., Zotto, P., Zumerle, G., Braghieri, A., Magnani, A., Montagna, P., Ratti, S.P., Re, V., Ressegotti, M., Riccardi, C., Salvini, P., Vai, I., Vitulo, P., Alunni Solestizi, L., Biasini, M., Bilei, G.M., Cecchi, C., Ciangottini, D., Fanò, L., Lariccia, P., Leonardi, R., Manoni, E., Mantovani, G., Mariani, V., Menichelli, M., Rossi, A., Santocchia, A., Spiga, D., Androsov, K., Azzurri, P., Bagliesi, G., Bianchini, L., Boccali, T., Borrello, L., Castaldi, R., Ciocci, M.A., Dell’Orso, R., Fedi, G., Fiori, F., Giannini, L., Giassi, A., Grippo, M.T., Ligabue, F., Manca, E., Mandorli, G., Messineo, A., Palla, F., Rizzi, A., Spagnolo, P., Tenchini, R., Tonelli, G., Venturi, A., Verdini, P.G., Barone, L., Cavallari, F., Cipriani, M., Daci, N., Del Re, D., Di Marco, E., Diemoz, M., Gelli, S., Longo, E., Marzocchi, B., Meridiani, P., Organtini, G., Pandolfi, F., Paramatti, R., Preiato, F., Rahatlou, S., Rovelli, C., Santanastasio, F., Amapane, N., Arcidiacono, R., Argiro, S., Arneodo, M., Bartosik, N., Bellan, R., Biino, C., Cartiglia, N., Cenna, F., Cometti, S., Costa, M., Covarelli, R., Demaria, N., Kiani, B., Mariotti, C., Maselli, S., Migliore, E., Monaco, V., Monteil, E., Monteno, M., Obertino, M.M., Pacher, L., Pastrone, N., Pelliccioni, M., Pinna Angioni, G.L., Romero, A., Ruspa, M., Sacchi, R., Shchelina, K., Sola, V., Solano, A., Soldi, D., Staiano, A., Belforte, S., Candelise, V., Casarsa, M., Cossutti, F., Della Ricca, G., Vazzoler, F., Zanetti, A., Kim, D.H., Kim, G.N., Kim, M.S., Lee, J., Lee, S., Lee, S.W., Moon, C.S., Oh, Y.D., Sekmen, S., Son, D.C., Yang, Y.C., Kim, H., Moon, D.H., Oh, G., Goh, J., Kim, T.J., Cho, S., Choi, S., Go, Y., Gyun, D., Ha, S., Hong, B., Jo, Y., Lee, K., Lee, K.S., Lee, S., Lim, J., Park, S.K., Roh, Y., Kim, H.S., Almond, J., Kim, J., Kim, J.S., Lee, H., Lee, K., Nam, K., Oh, S.B., Radburn-Smith, B.C., Seo, S., Yang, U.K., Yoo, H.D., Yu, G.B., Jeon, D., Kim, H., Kim, J.H., Lee, J.S.H., Park, I.C., Choi, Y., Hwang, C., Lee, J., Yu, I., Dudenas, V., Juodagalvis, A., Vaitkus, J., Ahmed, I., Ibrahim, Z.A., Md Ali, M.A.B., Mohamad Idris, F., Wan Abdullah, W.A.T., Yusli, M.N., Zolkapli, Z., Castaneda Hernandez, A., Murillo Quijada, J.A., Castilla-Valdez, H., De La Cruz-Burelo, E., Duran-Osuna, M.C., Heredia-De La Cruz, I., Lopez-Fernandez, R., Mejia Guisao, J., Rabadan-Trejo, R.I., Ramirez-Garcia, M., Ramirez-Sanchez, G., Reyes-Almanza, R., Sanchez-Hernandez, A., Carrillo Moreno, S., Oropeza Barrera, C., Vazquez Valencia, F., Eysermans, J., Pedraza, I., Salazar Ibarguen, H.A., Uribe Estrada, C., Morelos Pineda, A., Krofcheck, D., Bheesette, S., Butler, P.H., Ahmad, A., Ahmad, M., Asghar, M.I., Hassan, Q., Hoorani, H.R., Saddique, A., Shah, M.A., Shoaib, M., Waqas, M., Bialkowska, H., Bluj, M., Boimska, B., Frueboes, T., Górski, M., Kazana, M., Nawrocki, K., Szleper, M., Traczyk, P., Zalewski, P., Bunkowski, K., Byszuk, A., Doroba, K., Kalinowski, A., Konecki, M., Krolikowski, J., Misiura, M., Olszewski, M., Pyskir, A., Walczak, M., Bargassa, P., Beirão Da Cruz E Silva, C., Di Francesco, A., Faccioli, P., Galinhas, B., Gallinaro, M., Hollar, J., Leonardo, N., Lloret Iglesias, L., Nemallapudi, M.V., Seixas, J., Strong, G., Toldaiev, O., Vadruccio, D., Varela, J., Afanasiev, S., Alexakhin, V., Bunin, P., Gavrilenko, M., Golunov, A., Golutvin, I., Gorbounov, N., Karjavin, V., Lanev, A., Malakhov, A., Matveev, V., Moisenz, P., Palichik, V., Perelygin, V., Savina, M., Shmatov, S., Smirnov, V., Voytishin, N., Zarubin, A., Golovtsov, V., Ivanov, Y., Kim, V., Kuznetsova, E., Levchenko, P., Murzin, V., Oreshkin, V., Smirnov, I., Sosnov, D., Sulimov, V., Uvarov, L., Vavilov, S., Vorobyev, A., Andreev, Y., Dermenev, A., Gninenko, S., Golubev, N., Karneyeu, A., Kirsanov, M., Krasnikov, N., Pashenkov, A., Tlisov, D., Toropin, A., Epshteyn, V., Gavrilov, V., Lychkovskaya, N., Popov, V., Pozdnyakov, I., Safronov, G., Spiridonov, A., Stepennov, A., Stolin, V., Toms, M., Vlasov, E., Zhokin, A., Aushev, T., Chadeeva, M., Parygin, P., Philippov, D., Polikarpov, S., Popova, E., Rusinov, V., Andreev, V., Azarkin, M., Dremin, I., Kirakosyan, M., Rusakov, S.V., Terkulov, A., Baskakov, A., Belyaev, A., Boos, E., Dubinin, M., Dudko, L., Ershov, A., Gribushin, A., Klyukhin, V., Kodolova, O., Lokhtin, I., Miagkov, I., Obraztsov, S., Petrushanko, S., Savrin, V., Snigirev, A., Blinov, V., Dimova, T., Kardapoltsev, L., Shtol, D., Skovpen, Y., Azhgirey, I., Bayshev, I., Bitioukov, S., Elumakhov, D., Godizov, A., Kachanov, V., Kalinin, A., Konstantinov, D., Mandrik, P., Petrov, V., Ryutin, R., Slabospitskii, S., Sobol, A., Troshin, S., Tyurin, N., Uzunian, A., Volkov, A., Babaev, A., Baidali, S., Okhotnikov, V., Adzic, P., Cirkovic, P., Devetak, D., Dordevic, M., Milosevic, J., Alcaraz Maestre, J., Álvarez Fernández, A., Bachiller, I., Barrio Luna, M., Brochero Cifuentes, J.A., Cerrada, M., Colino, N., De La Cruz, B., Delgado Peris, A., Fernandez Bedoya, C., Fernández Ramos, J.P., Flix, J., Fouz, M.C., Gonzalez Lopez, O., Goy Lopez, S., Hernandez, J.M., Josa, M.I., 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Roeck, A., Deelen, N., Dobson, M., Dünser, M., Dupont, N., Elliott-Peisert, A., Everaerts, P., Fallavollita, F., Fasanella, D., Franzoni, G., Fulcher, J., Funk, W., Gigi, D., Gilbert, A., Gill, K., Glege, F., Guilbaud, M., Gulhan, D., Hegeman, J., Innocente, V., Jafari, A., Janot, P., Karacheban, O., Kieseler, J., Kornmayer, A., Krammer, M., Lange, C., Lecoq, P., Lourenço, C., Malgeri, L., Mannelli, M., Meijers, F., Merlin, J.A., Mersi, S., Meschi, E., Milenovic, P., Moortgat, F., Mulders, M., Ngadiuba, J., Orfanelli, S., Orsini, L., Pantaleo, F., Pape, L., Perez, E., Peruzzi, M., Petrilli, A., Petrucciani, G., Pfeiffer, A., Pierini, M., Pitters, F.M., Rabady, D., Racz, A., Reis, T., Rolandi, G., Rovere, M., Sakulin, H., Schäfer, C., Schwick, C., Seidel, M., Selvaggi, M., Sharma, A., Silva, P., Sphicas, P., Stakia, A., Steggemann, J., Tosi, M., Treille, D., Tsirou, A., Veckalns, V., Zeuner, W.D., Caminada, L., Deiters, K., Erdmann, W., Horisberger, R., Ingram, Q., Kaestli, H.C., 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Search for high-mass resonances decaying to a jet and a Lorentz-boosted resonance in proton-proton collisions at $\sqrt{s}=13\text{ }\text{ }\mathrm{TeV}

Physics letters / B 832, 137263 (2022). doi:10.1016/j.physletb.2022.137263 Published by North-Holland Publ., Amsterda

Two-particle Bose-Einstein correlations and their Lévy parameters in PbPb collisions at sNN\sqrt{s_\mathrm{NN}} = 5.02 TeV

Two-particle Bose-Einstein momentum correlation functions are studied for charged-hadron pairs in lead-lead collisions at a center-of-mass energy per nucleon pair of $\sqrt{s_\mathrm{NN}}$ = 5.02 TeV. The data sample, containing 4.27$\times10^{9}$ minimum bias events corresponding to an integrated luminosity of 0.607 nb$^{-1}$, was collected by the CMS experiment in 2018. The experimental results are discussed in terms of a L\'evy-type source distribution. The parameters of this distribution are extracted as functions of particle pair average transverse mass and collision centrality. These parameters include the L\'evy index or shape parameter ($\alpha$), the L\'evy scale parameter ($R$), and the correlation strength parameter ($\lambda$). The source shape, characterized by $\alpha$, is found to be neither Cauchy nor Gaussian, implying the need for a full L\'evy analysis. Similarly to what was previously found for systems characterized by Gaussian source radii, a hydrodynamical scaling is observed for the L\'evy $R$ parameter. The $\lambda$ parameter is studied in terms of the core-halo model.Comment: Submitted to Physical Review C. All figures and tables can be found at http://cms-results.web.cern.ch/cms-results/public-results/publications/HIN-21-011 (CMS Public Pages

Search for supersymmetry in hadronic final states with missing transverse energy using the variables αT and b-quark multiplicity in pp collisions at √s = 8 TeV

Submitted by Vitor Silverio Rodrigues ([email protected]) on 2014-05-27T11:30:34Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:48:49Z : No. of bitstreams: 1 2-s2.0-84883824987.pdf: 1540579 bytes, checksum: be6bbff5192436d9fcdbc367ffd1650e (MD5) Made available in DSpace on 2014-05-27T11:30:34Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-09-01 An inclusive search for supersymmetric processes that produce final states with jets and missing transverse energy is performed in pp collisions at a centre-of-mass energy of 8 TeV. The data sample corresponds to an integrated luminosity of 11.7 fb-1 collected by the CMS experiment at the LHC. In this search, a dimensionless kinematic variable, αT, is used to discriminate between events with genuine and misreconstructed missing transverse energy. The search is based on an examination of the number of reconstructed jets per event, the scalar sum of transverse energies of these jets, and the number of these jets identified as originating from bottom quarks. No significant excess of events over the standard model expectation is found. Exclusion limits are set in the parameter space of simplified models, with a special emphasis on both compressed-spectrum scenarios and direct or gluino-induced production of third-generation squarks. For the case of gluino-mediated squark production, gluino masses up to 950-1125 GeV are excluded depending on the assumed model. For the direct pair-production of squarks, masses up to 450 GeV are excluded for a single light first- or second-generation squark, increasing to 600 GeV for bottom squarks. © 2013 CERN for the benefit of the CMS collaboration. CERN, Geneva Yerevan Physics Institute, Yerevan Institut für Hochenergiephysik der OeAW, Wien National Centre for Particle and High Energy Physics, Minsk Universiteit Antwerpen, Antwerpen Vrije Universiteit Brussel, Brussel Université Libre de Bruxelles, Bruxelles Ghent University, Ghent Université Catholique de Louvain, Louvain-la-Neuve Université de Mons, Mons Centro Brasileiro de Pesquisas Fisicas, Rio de Janeiro Universidade do Estado do Rio de Janeiro, Rio de Janeiro Universidade Estadual Paulista, São Paulo Universidade Federal do ABC, São Paulo Institute for Nuclear Research and Nuclear Energy, Sofia University of Sofia, Sofia Institute of High Energy Physics, Beijing State Key Laboratory of Nuclear Physics and Technology Peking University, Beijing Universidad de Los Andes, Bogota Technical University of Split, Split University of Split, Split Institute Rudjer Boskovic, Zagreb University of Cyprus, Nicosia Charles University, Prague Academy of Scientific Research and Technology of the Arab Republic of Egypt Egyptian Network of High Energy Physics, Cairo National Institute of Chemical Physics and Biophysics, Tallinn Department of Physics University of Helsinki, Helsinki Helsinki Institute of Physics, Helsinki Lappeenranta University of Technology, Lappeenranta DSM/IRFU CEA/Saclay, Gif-sur-Yvette Laboratoire Leprince-Ringuet, Ecole Polytechnique IN2P3-CNRS, Palaiseau Institut Pluridisciplinaire Hubert Curien, Universite de Strasbourg, Universite de Haute Alsace Mulh CNRS/IN2P3, Strasbourg CNRS-IN2P3, Institut de Physique Nucléaire de Lyon Université de Lyon, Université Claude Bernard Lyon 1, Villeurbanne Institute of High Energy Physics and Informatization Tbilisi State University, Tbilisi I. Physikalisches Institut RWTH Aachen University, Aachen III. Physikalisches Institut A RWTH Aachen University, Aachen III. Physikalisches Institut B RWTH Aachen University, Aachen Deutsches Elektronen-Synchrotron, Hamburg University of Hamburg, Hamburg Institut für Experimentelle Kernphysik, Karlsruhe Institute of Nuclear and Particle Physics (INPP) NCSR Demokritos, Aghia Paraskevi University of Athens, Athens University of Ioánnina, Ioánnina KFKI Research Institute for Particle and Nuclear Physics, Budapest Institute of Nuclear Research ATOMKI, Debrecen University of Debrecen, Debrecen Panjab University, Chandigarh University of Delhi, Delhi Saha Institute of Nuclear Physics, Kolkata Bhabha Atomic Research Centre, Mumbai Tata Institute of Fundamental Research - EHEP, Mumbai Tata Institute of Fundamental Research - HECR, Mumbai Institute for Research in Fundamental Sciences (IPM), Tehran INFN Sezione di Bari, Bari Università di Bari, Bari Politecnico di Bari, Bari INFN Sezione di Bologna, Bologna Università di Bologna, Bologna INFN Sezione di Catania, Catania Università di Catania, Catania INFN Sezione di Firenze, Firenze Università di Firenze, Firenze INFN Laboratori Nazionali di Frascati, Frascati INFN Sezione di Genova, Genova Università di Genova, Genova INFN Sezione di Milano-Bicocca, Milano Università di Milano-Bicocca, Milano INFN Sezione di Napoli, Napoli Università di Napoli 'Federico II', Napoli Università della Basilicata (Potenza), Napoli Università G. 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Kidney and Cardiovascular Effects of Canagliflozin According to Age and Sex: A Post Hoc Analysis of the CREDENCE Randomized Clinical Trial

Rationale & Objective: It is unclear whether the effect of canagliflozin on adverse kidney and cardiovascular events in those with diabetic kid-ney disease varies by age and sex. We assessed the effects of canagliflozin among age group categories and between sexes in the Canagli-flozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) study.Study Design: Secondary analysis of a random-ized controlled trial. Setting & Participants: Participants in the CREDENCE trial. Intervention: Participants were randomly assigned to receive canagliflozin 100 mg/d or placebo.Outcomes: Primary composite outcome of kid-ney failure, doubling of serum creatinine con-centration, or death due to kidney or cardiovascular disease. Prespecified secondary and safety outcomes were also analyzed. Out-comes were evaluated by age at baseline (<60, 60-69, and >_70 years) and sex in the intention-to-treat population using Cox regression models.Results: The mean age of the cohort was 63.0 & PLUSMN; 9.2 years, and 34% were female. Older age and female sex were independently associ-ated with a lower risk of the composite of adverse kidney outcomes. There was no evidence that the effect of canagliflozin on the primary outcome (acomposite of kidney failure, a doubling of serum creatinine concentration, or death from kidney or cardiovascular causes) differed between age groups (HRs, 0.67 [95% CI, 0.52-0.87], 0.63 [0.4 8-0.82], and 0.89 [0.61-1.29] for ages <60, 60-69, and >_70 years, respectively; P = 0.3 for interaction) or sexes (HRs, 0.71 [95% CI, 0.5 4-0.95] and 0.69 [0.56-0.8 4] in women and men, respectively; P = 0.8 for interaction). No differences in safety outcomes by age group or sex were observed.Limitations: This was a post hoc analysis with multiple comparisons.Conclusions: Canagliflozin consistently reduced the relative risk of kidney events in people with diabetic kidney disease in both sexes and across age subgroups. As a result of greater background risk, the absolute reduction in adverse kidney outcomes was greater in younger participants.Funding: This post hoc analysis of the CREDENCE trial was not funded. The CREDENCE study was sponsored by Janssen Research and Development and was conducted collaboratively by the sponsor, an academic-led steering committee, and an academic research organization, George Clinical.Trial Registration: The original CREDENCE trial was registered at ClinicalTrials.gov with study number NCT02065791