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Not AvailablePresent study was conducted to generate baseline data on radionuclide concentration in commercially important crabs around Mumbai and Sindhudurg districts of Maharashtra, India. The activity concentration of U-238, Ra-228, K-40 and Pb-210 were calculated in different tissues of crabs for different species, with respect to seasonal and spatial variations. The order of accumulation was gills > exoskeleton > muscle. The study shows that the observed values varied depending upon the species, locality and environmental factors.Not Availabl

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Not AvailableThe present work deals with assessment of baseline radionuclide concentration in marine organisms around selected coasts of Maharashtra, India. This baseline study highlights concentrations of natural and fallout radionuclides in finfish and shellfish species found in the surrounding seawater. Water and fish samples were collected, processed, and analyzed for 238U, 226Ra, 228Ra, 232Th, 40K, and 137Cs by high-resolution gamma spectrometry. 238U, 226Ra, 228Ra, 232Th, 40K, and 137Cs concentrations were found to be in the range of ≤1.5, ≤2.0, ≤0.4, ≤1.5, ≤8.0 to 258, and ≤0.2 Bq/kg, respectively. The seasonal study revealed the maximum concentration in premonsoon season. Activity concentrations were higher in pelagic fish than those in demersal fish. A higher concentration factor was reported in shellfish than in finfish.Not Availabl

Polymer-mineral scaffold augments in vivo equine multipotent stromal cell osteogenesis

Abstract Background Use of bioscaffolds to direct osteogenic differentiation of adult multipotent stromal cells (MSCs) without exogenous proteins is a contemporary approach to bone regeneration. Identification of in vivo osteogenic contributions of exogenous MSCs on bioscaffolds after long-term implantation is vital to understanding cell persistence and effect duration. Methods This study was designed to quantify in vivo equine MSC osteogenesis on synthetic polymer scaffolds with distinct mineral combinations 9 weeks after implantation in a murine model. Cryopreserved, passage (P)1, equine bone marrow-derived MSCs (BMSC) and adipose tissue-derived MSCs (ASC) were culture expanded to P3 and immunophenotyped with flow cytometry. They were then loaded by spinner flask on to scaffolds composed of tricalcium phosphate (TCP)/hydroxyapatite (HA) (40:60; HT), polyethylene glycol (PEG)/poly-l-lactic acid (PLLA) (60:40; GA), or PEG/PLLA/TCP/HA (36:24:24:16; GT). Scaffolds with and without cells were maintained in static culture for up to 21 days or implanted subcutaneously in athymic mice that were radiographed every 3 weeks up to 9 weeks. In vitro cell viability and proliferation were determined. Explant composition (double-stranded (ds)DNA, collagen, sulfated glycosaminoglycan (sGAG), protein), equine and murine osteogenic target gene expression, microcomputed tomography (μCT) mineralization, and light microscopic structure were assessed. Results The ASC and BMSC number increased significantly in HT constructs between 7 and 21 days of culture, and BMSCs increased similarly in GT constructs. Radiographic opacity increased with time in GT-BMSC constructs. Extracellular matrix (ECM) components and dsDNA increased significantly in GT compared to HT constructs. Equine and murine osteogenic gene expression was highest in BMSC constructs with mineral-containing scaffolds. The HT constructs with either cell type had the highest mineral deposition based on μCT. Regardless of composition, scaffolds with cells had more ECM than those without, and osteoid was apparent in all BMSC constructs. Conclusions In this study, both exogenous and host MSCs appear to contribute to in vivo osteogenesis. Addition of mineral to polymer scaffolds enhances equine MSC osteogenesis over polymer alone, but pure mineral scaffold provides superior osteogenic support. These results emphasize the need for bioscaffolds that provide customized osteogenic direction of both exo- and endogenous MSCs for the best regenerative potential

Charge radii of thallium isotopes near the <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mi>N</mml:mi><mml:mo>=</mml:mo><mml:mn>126</mml:mn></mml:mrow></mml:math> shell closure

The changes in the mean-squared charge radius of Tlg209 (N=128) and Tlm207 (N=126) relative to Tl205 have been measured for the first time using the in-source laser resonance-ionization spectroscopy technique with the Laser Ion Source and Trap (LIST) at ISOLDE (CERN). The application of the LIST suppresses the dominant background from isobaric francium isotopes and allows access to thallium nuclides with A⩾207. The characteristic kink in the charge radii at the N=126 neutron shell closure, as well as the odd-even effect similar to that in the adjacent bismuth, lead, and mercury isotopic chains, have been observed. The self-consistent theory of finite Fermi systems based on the energy density functional by Fayans reproduces the behavior of charge radii in these isotopic chains near N=126. The comparison with calculations in the framework of the relativistic mean field (RMF) approach is also presented. In the case of the Fayans functional it is a specific form of pairing interaction with the dependence on the density gradient that is essential to provide agreement with the experimental charge radii. In particular, the kink is reproduced without the inversion of g9/2 and i11/2 neutron single-particle states, which is a prerequisite to correctly describe the kink in the RMF models. Published by the American Physical Society 2024 </jats:sec