2,310 research outputs found
Bulk spectral function sum rule in QCD-like theories with a holographic dual
We derive the sum rule for the spectral function of the stress-energy tensor
in the bulk (uniform dilatation) channel in a general class of strongly coupled
field theories. This class includes theories holographically dual to a theory
of gravity coupled to a single scalar field, representing the operator of the
scale anomaly. In the limit when the operator becomes marginal, the sum rule
coincides with that in QCD. Using the holographic model, we verify explicitly
the cancellation between large and small frequency contributions to the
spectral integral required to satisfy the sum rule in such QCD-like theories.Comment: 16 pages, 2 figure
Sum Rules from an Extra Dimension
Using the gravity side of the AdS/CFT correspondence, we investigate the
analytic properties of thermal retarded Green's functions for scalars,
conserved currents, the stress tensor, and massless fermions. We provide some
results concerning their large and small frequency behavior and their pole
structure. From these results, it is straightforward to prove the validity of
various sum rules on the field theory side of the duality. We introduce a novel
contraction mapping we use to study the large frequency behavior of the Green's
functions.Comment: v2: 23 pages (plus appendix), revised presentation, discussion of
branch cuts moved to appendix, and some minor changes; v1: 24 pages (plus
appendix
Epithelial–mesenchymal transition is driven by transcriptional and post transcriptional modulations in copd: Implications for disease progression and new therapeutics
© 2019 Eapen et al. COPD is a common and highly destructive disease with huge impacts on people and health services throughout the world. It is mainly caused by cigarette smoking though environmental pollution is also significant. There are no current treatments that affect the overall course of COPD; current drugs focus on symptomatic relief and to some extent reducing exacerbation rates. There is an urgent need for in-depth studies of the fundamental pathogenic mechanisms that underpin COPD. This is vital, given the fact that nearly 40%– 60% of the small airway and alveolar damage occurs in COPD well before the first measurable changes in lung function are detected. These individuals are also at a high risk of lung cancer. Current COPD research is mostly centered around late disease and/or innate immune activation within the airway lumen, but the actual damage to the airway wall has early onset. COPD is the end result of complex mechanisms, possibly triggered through initial epithelial activation. To change the disease trajectory, it is crucial to understand the mechanisms in the epithelium that are switched on early in smokers. One such mechanism we believe is the process of epithelial to mesenchymal transition. This article highlights the importance of this profound epithelial cell plasticity in COPD and also its regulation. We consider that understanding early changes in COPD will open new windows for therapy
Holographic Superconductors in a Cohesive Phase
We consider a four-dimensional N=2 gauged supergravity coupled to matter
fields. The model is obtained by a U(1) gauging of a charged hypermultiplet and
therefore it is suitable for the study of holographic superconductivity. The
potential has a topologically flat direction and the parameter running on this
"moduli space" labels the new superconducting black holes. Zero temperature
solutions are constructed and the phase diagram of the theory is studied. The
model has rich dynamics. The retrograde condensate is just a special case in
the new class of black holes. The calculation of the entanglement entropy makes
manifest the properties of a generic solution and the superconductor at zero
temperature is in a confined cohesive phase. The parameter running on the
topologically flat direction is a marginal coupling in the dual field theory.
We prove this statement by considering the way double trace deformations are
treated in the AdS/CFT correspondence. Finally, we comment on a possible
connection, in the context of gauge/gravity dualities, between the geometry of
the scalar manifold in N=2 supergravity models and the space of marginal
deformations of the dual field theory.Comment: 32 pages, 11 figures. Introduction rewritten and clarified, comments
and details on section 4 added, acknowledgements rectified. To appear in JHE
Hydrodynamics of a 5D Einstein-dilaton black hole solution and the corresponding BPS state
We apply the potential reconstruction approach to generate a series of
asymptotically AdS (aAdS) black hole solutions, with a self-interacting bulk
scalar field. Based on the method, we reproduce the pure AdS solution as a
consistency check and we also generate a simple analytic 5D black hole
solution. We then study various aspects of this solution, such as temperature,
entropy density and conserved charges. Furthermore, we study the hydrodynamics
of this black hole solution in the framework of fluid/gravity duality, e.g. the
ratio of the shear viscosity to the entropy density. In a degenerate case of
the 5D black hole solution, we find that the c function decreases monotonically
from UV to IR as expected. Finally, we investigate the stability of the
degenerate solution by studying the bosonic functional energy of the gravity
and the Witten-Nester energy . We confirm that the degenerate solution
is a BPS domain wall solution. The corresponding superpotential and the
solution of the killing spinor equation are found explicitly.Comment: V2: 23 pages, no figure, minor changes, typos corrected, new
references and comments added, version accepted by JHE
Massive Quantum Liquids from Holographic Angel's Trumpets
We explore the small-temperature regime in the deconfined phase of massive
fundamental matter at finite baryon number density coupled to the 3+1
dimensional N=4 SYM theory. In this setting, we can demonstrate a new type of
non-trivial temperature-independent scaling solutions for the probe brane
embeddings. Focusing mostly on matter supported in 2+1 dimensions, the
thermodynamics indicate that there is a quantum liquid with interesting
density-dependent low-temperature physics. We also comment about 3+1 and 1+1
dimensional systems, where we further find for example a new thermodynamic
instability.Comment: 18+1 pages, 6 figures; replaced fig. 6 and comments in sec. 5.2;
minor explanations added and typos fixed, final version published in JHEP
(modulo fig. 3); factor of \sqrt{\lambda} and corresponding comments fixe
Transport coefficients, membrane couplings and universality at extremality
We present an efficient method for computing the zero frequency limit of
transport coefficients in strongly coupled field theories described
holographically by higher derivative gravity theories. Hydrodynamic parameters
such as shear viscosity and conductivity can be obtained by computing residues
of poles of the off-shell lagrangian density. We clarify in which sense these
coefficients can be thought of as effective couplings at the horizon, and
present analytic, Wald-like formulae for the shear viscosity and conductivity
in a large class of general higher derivative lagrangians. We show how to apply
our methods to systems at zero temperature but finite chemical potential. Our
results imply that such theories satisfy universally in the
Einstein-Maxwell sector. Likewise, the zero frequency limit of the real part of
the conductivity for such systems is shown to be universally zero, and we
conjecture that higher derivative corrections in this sector do not modify this
result to all orders in perturbation theory.Comment: 29 pages, v2: Small text changes for clarity, typos correcte
Abelian-Higgs and Vortices from ABJM: towards a string realization of AdS/CMT
We present ans\"{a}tze that reduce the mass-deformed ABJM model to gauged
Abelian scalar theories, using the fuzzy sphere matrices . One such
reduction gives a Toda system, for which we find a new type of nonabelian
vortex. Another gives the standard Abelian-Higgs model, thereby allowing us to
embed all the usual (multi-)vortex solutions of the latter into the ABJM model.
By turning off the mass deformation at the level of the reduced model, we can
also continuously deform to the massive theory in the massless ABJM
case. In this way we can embed the Landau-Ginzburg model into the AdS/CFT
correspondence as a consistent truncation of ABJM. In this context, the mass
deformation parameter and a field VEV act as and
respectively, leading to a well-motivated AdS/CMT construction from string
theory. To further this particular point, we propose a simple model for the
condensed matter field theory that leads to an approximate description for the
ABJM abelianization. Finally, we also find some BPS solutions to the
mass-deformed ABJM model with a spacetime interpretation as an M2-brane ending
on a spherical M5-brane.Comment: 43 pages, latex, explanations added in the introduction, end of
section 4, and on page 2
M-Branes and Metastable States
We study a supersymmetry breaking deformation of the M-theory background
found in arXiv:hep-th/0012011. The supersymmetric solution is a warped product
of R^{2,1} and the 8-dimensional Stenzel space, which is a higher dimensional
generalization of the deformed conifold. At the bottom of the warped throat
there is a 4-sphere threaded by \tilde{M} units of 4-form flux. The dual
(2+1)-dimensional theory has a discrete spectrum of bound states. We add p
anti-M2 branes at a point on the 4-sphere, and show that they blow up into an
M5-brane wrapping a 3-sphere at a fixed azimuthal angle on the 4-sphere. This
supersymmetry breaking state turns out to be metastable for p / \tilde{M} <
0.054. We find a smooth O(3)-symmetric Euclidean bounce solution in the
M5-brane world volume theory that describes the decay of the false vacuum.
Calculation of the Euclidean action shows that the metastable state is
extremely long-lived. We also describe the corresponding metastable states and
their decay in the type IIA background obtained by reduction along one of the
spatial directions of R^{2,1}.Comment: 33 pages, 5 figures; v2 note adde
On The Phase Structure and Thermodynamic Geometry of R-Charged Black Holes
We study the phase structure and equilibrium state space geometry of
R-charged black holes in , 4 and 7 and the corresponding rotating ,
and branes. For various charge configurations of the compact black
holes in the canonical ensemble we demonstrate new liquid-gas like phase
coexistence behaviour culminating in second order critical points. The critical
exponents turn out to be the same as that of four dimensional asymptotically
AdS black holes in Einstein Maxwell theory. We further establish that the
regions of stability for R-charged black holes are, in some cases, more
constrained than is currently believed, due to properties of some of the
response coefficients. The equilibrium state space scalar curvature is
calculated for various charge configurations, both for the case of compact as
well as flat horizons and its asymptotic behaviour with temperature is
established.Comment: 1 + 33 pages, LaTeX, 25 figures. References adde
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