836 research outputs found

    Sobre el carácter histórico del "Cantar de mio Cid"

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    "Mesturar" y la semántica hispano-árabe

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    Dos observaciones sintáctico-estilísticas a las "Coplas" de Manrique

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    Adición a "Soy quien soy"

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    Sobre la cántica "Eya velar"

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    Evolution of Blister-Type HII Regions in a Magnetized Medium

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    We use the three-dimensional Athena ionizing radiation-magnetohydrodynamics (IRMHD) code to simulate blister-type HII regions driven by stars on the edge of magnetized gas clouds. We compare these to simulations of spherical HII regions where the star is embedded deep within a cloud, and to non-magnetized simulations of both types, in order to compare their ability to drive turbulence and influence star formation. We find that magnetized blister HII regions can be very efficient at injecting energy into clouds. This is partly a magnetic effect: the magnetic energy added to a cloud by an HII region is comparable to or larger than the kinetic energy, and magnetic fields can also help collimate the ejected gas, increasing its energy yield. As a result of these effects, a blister HII region expanding into a cloud with a magnetic field perpendicular to its edge injects twice as much energy by 5 Myr as a non-magnetized blister HII region driven by a star of the same luminosity. Blister HII regions are also more efficient at injecting kinetic energy than spherical HII regions, due to the recoil provided by escaping gas, but not by as much as predicted by some analytic approximations.Comment: 15 pages, 17 figures, 1 tabl

    The Milky Way's dark matter halo appears to be lopsided

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    The atomic hydrogen gas (HI) disk in the outer region (beyond ~10 kpc from the centre) of Milky Way can provide valuable information about the structure of the dark matter halo. The recent 3-D thickness map of the outer HI disk from the all sky 21-cm line LAB survey, gives us a unique opportunity to investigate the structure of the dark matter halo of Milky Way in great detail. A striking feature of this new survey is the North-South asymmetry in the thickness map of the atomic hydrogen gas. Assuming vertical hydrostatic equilibrium under the total potential of the Galaxy, we derive the model thickness map of the HI gas. We show that simple axisymmetric halo models, such as softened isothermal halo (producing a flat rotation curve with V_c ~ 220 km/s) or any halo with density falling faster than the isothermal one, are not able to explain the observed radial variation of the gas thickness. We also show that such axisymmetric halos along with different HI velocity dispersion in the two halves, cannot explain the observed asymmetry in the thickness map. Amongst the non-axisymmetric models, it is shown that a purely lopsided (m=1, first harmonic) dark matter halo with reasonable HI velocity dispersion fails to explain the North-South asymmetry satisfactorily. However, we show that by superposing a second harmonic (m=2) out of phase onto a purely lopsided halo e.g. our best fit and more acceptable model A (with parameters \epsilon_{h}^{1}=0.2, \epsilon_{h}^{2}=0.18 and \sigma_{HI}=8.5 km/s) can provide an excellent fit to the observation and reproduce the North-South asymmetry naturally. The emerging picture of the asymmetric dark matter halo is supported by the \Lambda CDM halos formed in the cosmological N-body simulation.Comment: 37 pages, 8 figures, accepted for publication in Ap

    GRFS and CRFS in alternative donor hematopoietic cell transplantation for pediatric patients with acute leukemia.

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    We report graft-versus-host disease (GVHD)-free relapse-free survival (GRFS) (a composite end point of survival without grade III-IV acute GVHD [aGVHD], systemic therapy-requiring chronic GVHD [cGVHD], or relapse) and cGVHD-free relapse-free survival (CRFS) among pediatric patients with acute leukemia (n = 1613) who underwent transplantation with 1 antigen-mismatched (7/8) bone marrow (BM; n = 172) or umbilical cord blood (UCB; n = 1441). Multivariate analysis was performed using Cox proportional hazards models. To account for multiple testing, P \u3c .01 for the donor/graft variable was considered statistically significant. Clinical characteristics were similar between UCB and 7/8 BM recipients, because most had acute lymphoblastic leukemia (62%), 64% received total body irradiation-based conditioning, and 60% received anti-thymocyte globulin or alemtuzumab. Methotrexate-based GVHD prophylaxis was more common with 7/8 BM (79%) than with UCB (15%), in which mycophenolate mofetil was commonly used. The univariate estimates of GRFS and CRFS were 22% (95% confidence interval [CI], 16-29) and 27% (95% CI, 20-34), respectively, with 7/8 BM and 33% (95% CI, 31-36) and 38% (95% CI, 35-40), respectively, with UCB (P \u3c .001). In multivariate analysis, 7/8 BM vs UCB had similar GRFS (hazard ratio [HR], 1.12; 95% CI, 0.87-1.45; P = .39), CRFS (HR, 1.06; 95% CI, 0.82-1.38; P = .66), overall survival (HR, 1.07; 95% CI, 0.80-1.44; P = .66), and relapse (HR, 1.44; 95% CI, 1.03-2.02; P = .03). However, the 7/8 BM group had a significantly higher risk for grade III-IV aGVHD (HR, 1.70; 95% CI, 1.16-2.48; P = .006) compared with the UCB group. UCB and 7/8 BM groups had similar outcomes, as measured by GRFS and CRFS. However, given the higher risk for grade III-IV aGVHD, UCB might be preferred for patients lacking matched donors. © 2019 American Society of Hematology. All rights reserved
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