Dermatophylosis in Santa Inês sheep from Distrito Federal

Relataram-se quatro casos de dermatofilose em ovinos da raça Santa Inês, no período de um ano. Microscopicamente observaram-se filamentos na forma de "trilho de bonde" e zoósporos nos quatro casos. A tentativa do isolamento do microrganismo foi realizada por meio do método de Haalstra e em apenas um caso obteve-se sucesso, observando-se colônias de aparência lisa, formato circular, cor amarelada e hemolítica em ágar sangue. O exame direto com coloração de Gram mostrou-se um método bastante eficiente na confirmação da presença do microrganismo afetando a epiderme em razão da morfologia típica do agente.Four cases of dermatophylosis were reported in Santa Inês sheep in a study period of one year. Microscopically, septate filaments and coccoid forms zoospores were observed. Attempts to isolate the microorganisms were accomplished using Haastra's method and it was successful in only one case. Dermatophilus congolensis samples have grown on blood agar, colonies where hemolytic, small, round and pigmentation vary from yellow to orange. The gram staining method was efficient to confirm the presence of the microorganism affecting the epidermis due to typical morphology of the agent

Pharmacology And Toxicology Of Peumus Boldus And Baccharis Genistelloides [farmacologia E Toxicologia De Peumus Boldus E Baccharis Genistelloides]

There are a great number of medicinal plants without any scientific confirmation about their efficacy and safety. This paper is a short review about two medicinal plants, "boldo do chile" (Peumus boldus) and "carqueja" (Baccharis genistelloides). Pharmacological studies have confirmed several popular indications for P. boldus and B. genistelloides, besides have established a relationship between isolated compounds from these extracts and the pharmacological effects observed. On the other hand, toxicological researches have pointed out that P. boldus tea should not be consumed during a long period (potential hepatotoxicity) and by pregnant, especially during the first three months. Moreover, B. genistelloides tea must be prohibited for pregnant because of confirmed abortive action, and for patients using medicines for blood pressure disorders. These studies point out the continuous necessity of more studies about medicinal plants; only with this knowledge it will be possible a safe and efficient use.182295300Abad, M.J., Bermejo, P., Gonzales, E., Iglesias, I., Irurzun, A., Carrasco, L., Antiviral activity of Bolivian plant extracts (1999) Gen Pharmacol, 32, pp. 499-503Agra, M.F., França, P.F., Barbosa-Filho, J.M., Synopsis of the plants known as medicinal and poisonous in Northeast of Brazil (2007) Rev Bras Farmacogn, 17, pp. 114-140Almeida, E.R., Melo, A.M., Xavier, H., Toxicological evaluation of the hydro-alcohol extract of the dry leaves of Peumus boldus and boldine in rats (2000) Phytother Res, 14, pp. 99-102Alonso JR 1998. Tratado de Fitomedicina - bases clínicas y farmacológicas. ISIS Ediciones S. R. 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(2005) Quim Nova, 28, pp. 85-94Vila, R., Valenzuela, L., Bello, H., Cañigueral, S., Montes, M., Adzet, T., Composition and antimicrobial activity of the essential oil of Peumus boldus leaves (1999) Planta Med, 65, pp. 178-179Vogel, H., Razmilic, I., Muñoz, M., Doll, U., San Martin, J., Studies of genetic variation of essential oil and alkaloid content in boldo (Peumus boldus) (1999) Planta Med, 65, pp. 90-91Youn, Y.C., Kwon, O.S., Han, E.S., Song, J.H., Shin, Y.K., Lee, C.S., Protective effect of boldine on dopamine-induced membrane permeability transition in brain mitochondria and viability loss in PC12 cells (2002) Biochem Pharmacol, 63, pp. 495-50