715 research outputs found

    Portfolio Vol. II N 2

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    Browne, Phil. Beaver ad Sawyer at Night . Picture. 2. Varney, Chester. To Dream Beyond . Prose. 3. West, Bill C. Admonition Poem. 6. West, Bill C. Insomnia Poem. 6. Barlow, Don. Heart Determines . Prose. 7. Gordon, Robert. From an Unknown Innocent to... Poem, 11. Black, James. Playing Around . Prose. 13. Parsons, Edith. The Turtle Baby . Picture. 14. Deeds, Ed. Raymond Scott - - Classic Swing . Prose. 15. Schrechkengost, Viktor. Black Sheep-The Creature God Forgot . Picture. 14. Smith, Bob. Review of New Recordings . Prose. 15. Saunders, Paul. Book Reviews and Comments . Prose. 16. Browne, Phil. to Patsy . Picture. 17. Sandor, Joseph. Meditation . Picture. 18. Maxwell, Kenneth. Unnamed. Poem. 18. Sweitzer, Harry J. Social Life at Denison . Prose. 19. Flory Doris. The Student Rationalizes . Poem. 20. Flory Doris. On Noisess . Poem. 20. Bethune, Don. Senior\u27s Lament . Poem. 20. Flory, Doris. Lines on Lines . Poem. 20. Beckham, Adela. My Man . Poem. 20

    Pros Who Know at The University of Maine

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    In January 2016, alumni, and current students from a variety of academic fields gathered at Buchanan Alumni House to swap questions and answers about the keys to landing that first job and career success. Billed as “Pros Who Know,” the event was a collaborative effort of the Alumni Association and UMaine’s Career Center. The alumni panel share their experiences and insights on career search strategies; offered interview, resume, and cover letter tips; related stories from their own career paths; and reflected about things they wish they had known when entering the workforce. Students commented that all the UMaine alumni were inspirational - and they appreciated getting to mingle with the panelists and other professionals

    Calcitonin gene-related peptide promotes cellular changes in trigeminal neurons and glia implicated in peripheral and central sensitization

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    <p>Abstract</p> <p>Background</p> <p>Calcitonin gene-related peptide (CGRP), a neuropeptide released from trigeminal nerves, is implicated in the underlying pathology of temporomandibular joint disorder (TMD). Elevated levels of CGRP in the joint capsule correlate with inflammation and pain. CGRP mediates neurogenic inflammation in peripheral tissues by increasing blood flow, recruiting immune cells, and activating sensory neurons. The goal of this study was to investigate the capability of CGRP to promote peripheral and central sensitization in a model of TMD.</p> <p>Results</p> <p>Temporal changes in protein expression in trigeminal ganglia and spinal trigeminal nucleus were determined by immunohistochemistry following injection of CGRP in the temporomandibular joint (TMJ) capsule of male Sprague-Dawley rats. CGRP stimulated expression of the active forms of the MAP kinases p38 and ERK, and PKA in trigeminal ganglia at 2 and 24 hours. CGRP also caused a sustained increase in the expression of c-Fos neurons in the spinal trigeminal nucleus. In contrast, levels of P2X<sub>3 </sub>in spinal neurons were only significantly elevated at 2 hours in response to CGRP. In addition, CGRP stimulated expression of GFAP in astrocytes and OX-42 in microglia at 2 and 24 hours post injection.</p> <p>Conclusions</p> <p>Our results demonstrate that an elevated level of CGRP in the joint, which is associated with TMD, stimulate neuronal and glial expression of proteins implicated in the development of peripheral and central sensitization. Based on our findings, we propose that inhibition of CGRP-mediated activation of trigeminal neurons and glial cells with selective non-peptide CGRP receptor antagonists would be beneficial in the treatment of TMD.</p

    Modelling and mapping of exceedance of critical loads and critical levels for acidification and eutrophication in the UK 2013-2016. Final report

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    This report covers the work of the original contract (2013-15) and the following one-year extension (2015-16). The overall purpose of this project was to maintain, and where appropriate update, the UK critical loads database, and to provide estimates of critical load and critical level exceedance based on current pollutant deposition or concentrations, and scenarios for the future. The exceedance results were used to inform policy makers on the areas of sensitive habitats and designated sites potentially at risk from air pollution and were updated annually to provide a UK indicator of the impacts of air pollution on ecosystems. The project also supported the UK National Focal Centre (NFC) for critical loads modelling and mapping. The 1-year extension to this contract additionally included the biodiversity modelling required to enable the UK NFC to begin work in preparation for responding to the 2015-17 “Call for Data” under the UNECE Convention on Long-Range Transboundary Air Pollution (CLRTAP)

    Portfolio Vol. II N 4

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    Browne, Phil. Alumni . Picture. 2. Martindale, Virginia. A Statue By Jude . Prose. 3. Maxwell, Robert. Reflections . Poem. 6. Lewis, Lucy. Quiet Zone . Prose. 7. Varney, Chester. Tinder Box . Prose. 9. Beckham, Adela. Spring Harvest . Poem. 10. Beckham, Adela. Morning . Poem. 10. Black, James. The Drama at Denison . Prose. 11. Mackie, Reino. Landscape . Picture. 6. Flory, Doris. April Showers . Poem. 14. Flory, Doris. Aspiration . Poem. 14. Wager, Dick. Solitude . Poem. 14. Wager, Dick. Regret . Poem. 14. Bastida, Sorella y. Children on the Beach . Picture. 14. Saunders, Paul. Review of New Books . Prose. 15. Smith, Bob. Review of New Recordings . Prose. 15. Mitchell, Dave. A Farmyard . Picture. 16. Bonnet, Elsie. Hidden Village . Picture. 16. Taylor, Dave. Concerning Art . Prose. 17. Browne, Phil. Master Craftsman . Picture. 18. Deeds, Ed. Brothers, Sing On . Prose. 19. Boyd, Kate Olive. Spring at Denison . Poem. 20. Barss, William. Landscape . Picture. 20. Deane, Dorothy. The Taming of the Shrew . Prose. 21

    Evidence-based obstetrics in four hospitals in China: An observational study to explore clinical practice, women's preferences and provider's views

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    BACKGROUND: Evidence-based obstetric care is widely promoted in developing countries, but the success of implementation is not known. Using selected childbirth care procedures in four hospitals in Shanghai, we compared practice against evidence-based information, and explored user and provider views about each procedure. METHODS: Observational study. Using the Cochrane Library, we identified six procedures that should be avoided as routine and two that should be encouraged. Procedure rate determined by exit interviews with women, verified using hospital notes. Views of women and providers explored with in depth interviews. The study sites were three hospitals in Shanghai and one in neighbouring province of Jiangsu. 150 women at each centre for procedure rate, and 48 in-depth interviews with women and providers. RESULTS: Vaginal births were 50% (303/599) of the total. Of the six practices where evidence suggests they should be avoided as routine, three were performed with rates above 70%: pubic shaving (3 hospitals), rectal examination (3 hospitals), and episiotomy (3 hospitals). Most women delivered lying down, pain relief was rarely given, and only in the urban district hospital did women routinely have a companion. Most women wanted support or companionship during labour and to be given pain relief; but current practice is insufficient to meet women's needs. CONCLUSION: Obstetric practice is not following best available evidence in the hospitals studied. There is a need to adjust hospital policy to support the use of interventions proven to be of benefit to women during childbirth, and develop approaches that ensure clinical practice changes
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