Facial Expression Restoration Based on Improved Graph Convolutional Networks

Facial expression analysis in the wild is challenging when the facial image is with low resolution or partial occlusion. Considering the correlations among different facial local regions under different facial expressions, this paper proposes a novel facial expression restoration method based on generative adversarial network by integrating an improved graph convolutional network (IGCN) and region relation modeling block (RRMB). Unlike conventional graph convolutional networks taking vectors as input features, IGCN can use tensors of face patches as inputs. It is better to retain the structure information of face patches. The proposed RRMB is designed to address facial generative tasks including inpainting and super-resolution with facial action units detection, which aims to restore facial expression as the ground-truth. Extensive experiments conducted on BP4D and DISFA benchmarks demonstrate the effectiveness of our proposed method through quantitative and qualitative evaluations.Comment: Accepted by MMM202

Measurements of the branching fraction and polarization in B+->rho K-+(*0) decays

We present the results of a study of the charmless vector-vector decay B+->rho K-+(*0), based on 253 fb(-1) of data collected with the Belle detector at the KEKB asymmetric-energy e(+)e(-) collider. We obtain the branching fraction B(B+->rho K-+(*0))=[8.9 +/- 1.7(stat)+/- 1.2(syst)]x10(-6). We also perform a helicity analysis of the rho and K-* vector mesons, and obtain the longitudinal polarization fraction f(L)(B+->rho K-+(*0))=0.43 +/- 0.11(stat)(-0.02)(+0.05)(syst)

A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome

Down syndrome, caused by an extra copy of chromosome 21, is associated with a greatly increased risk of early onset Alzheimer disease. It is thought that this risk is conferred by the presence of three copies of the gene encoding amyloid precursor protein (APP), an Alzheimer risk factor, although the possession of extra copies of other chromosome 21 genes may also play a role. Further study of the mechanisms underlying the development of Alzheimer disease in Down syndrome could provide insights into the mechanisms that cause dementia in the general population

Measurement of forward-backward asymmetry and wilson coefficients in B -> K(*)l(+)l(-)

We report the first measurement of the forward-backward asymmetry and the ratios of Wilson coefficients A(9)/A(7) and A(10)/A(7) in B -> K(*)l(+)l(-), where l represents an electron or a muon. We find evidence for the forward-backward asymmetry with a significance of 3.4 sigma. The results are obtained from a data sample containing 386x10(6) (B) over bar pairs that were collected on the Upsilon(4S) resonance with the Belle detector at the KEKB asymmetric-energy e(+)e(-) collider

Measurements of B decays to two kaons

We report measurements of B meson decays to two kaons using 253 fb(-1) of data collected with the Belle detector at the KEKB energy-asymmetric e(+)e(-) collider. We find evidence for signals in B+->(K) over bar K-0(+) and B-0-> K-0(K) over bar (0) with significances of 3.0 sigma and 3.5 sigma, respectively. (Charge-conjugate modes are included.) The corresponding branching fractions are measured to be B(B+->(K) over bar K-0(+))=(1.0 +/- 0.4 +/- 0.1)x10(-6) and B(B-0-> K-0(K) over bar (0))=(0.8 +/- 0.3 +/- 0.1)x10(-6). These decay modes are examples of hadronic b -> d transitions. No signal is observed in the decay B-0-> K+K-, and we set an upper limit of 3.7x10(-7) at 90% confidence level

Measurement of polarization and triple-product correlations in B -> phi K-* decays

We present measurements of decay amplitudes and triple-product correlations in B ->phi K-* decays based on 253 fb(-1) of data recorded at the Upsilon(4S) resonance with the Belle detector at the KEKB e(+)e(-) storage ring. The decay amplitudes for the three different helicity states are determined from the angular distributions of final-state particles. The longitudinal polarization amplitudes are found to be 0.45 +/- 0.05 +/- 0.02 for B-0->phi K-*0 and 0.52 +/- 0.08 +/- 0.03 for B+->phi K*+ decays. CP- and T-odd CP-violating triple-product asymmetries are measured to be consistent with zero

Prevalence and definition of drooling in Parkinson’s disease: a systematic review

Drooling (saliva loss) is a frequently reported symptom in patients with Parkinson’s disease (PD), but an accurate estimate of the prevalence of drooling is lacking. The aim of this study was to systematically review the prevalence of drooling in published research papers. A systematic PubMed and CINAHL search was done, including studies published until January 2009. Eight studies were found, presenting prevalence rates of drooling based on responses of PD patients to questionnaires. The statistical heterogeneity was highly significant (P < 0.0001), with prevalence rates ranging from 32 to 74%. The pooled prevalence estimate with random effect analysis was of 56% (95% CI 44–67) for PD patients and 14% (95% CI 3–25) for healthy controls; the pooled relative risk (RR) with random effect analysis was 5.5 (95% CI 2.1–14.4). All studies reported data of community dwelling idiopathic PD patients, with a mean age around 65 years and mild PD in 50–60% of the cases. Heterogeneity was mainly caused by differences in definition or frequency of drooling. The highest prevalence rates included nocturnal drooling where others noted only diurnal drooling. Analysis of the data of two studies showed that drooling is reported frequently by 22–26% of the patients. Prevalence rates were lower in milder PD patients. The summarized findings demonstrate that drooling can be present in half of all PD patients. In about a quarter of PD patients, drooling appears to be a frequently occurring problem. We recommend to report drooling in future studies with more detailed consideration of severity, frequency and nocturnal versus diurnal complaints

Changes in the Brain Microstructure of Children with Primary Monosymptomatic Nocturnal Enuresis: A Diffusion Tensor Imaging Study

Background: Primary monosymptomatic nocturnal enuresis (PMNE) is a common disorder in school-aged children. Previous studies have suggested that a developmental delay might play a role in the pathology of children with PMNE. However, microstructural abnormalities in the brains of these children have not been thoroughly investigated. Methodology/Principal Findings: In this work, we evaluated structural changes in the brains of children with PMNE using diffusion tensor imaging (DTI). Two groups consisting of 26 children with PMNE and 26 healthy controls were scanned using magnetic resonance DTI. The diffusion parameters of fractional anisotropy (FA) and mean diffusivity (MD) were subjected to whole-brain, voxel-wise group comparisons using statistical parametric mapping (SPM). When compared to healthy subjects, children with PMNE showed both a decrease in FA and an increase in MD in the thalamus. MD also increased in the frontal lobe, the anterior cingulate cortex and the insula; these areas are all involved in controlling micturition. The significant changes seen in the thalamus could affect both urine storage and arousal from sleep. Conclusions/Significance: The microstructure abnormalities were observed in the thalamus, the medial frontal gyrus, the anterior cingulate cortex and the insula, which are involved in micturition control network. This indicates developmenta

Overnight switch from ropinirole to transdermal rotigotine patch in patients with Parkinson disease

<p>Abstract</p> <p>Background</p> <p>A recent trial involving predominantly Caucasian subjects with Parkinson Disease (PD) showed switching overnight from an oral dopaminergic agonist to the rotigotine patch was well tolerated without loss of efficacy. However, no such data have been generated for Korean patients.</p> <p>Methods</p> <p>This open-label multicenter trial investigated PD patients whose symptoms were not satisfactorily controlled by ropinirole, at a total daily dose of 3 mg to 12 mg, taken as monotherapy or as an adjunct to levodopa. Switching treatment from oral ropinirole to transdermal rotigotine was carried out overnight, with a dosage ratio of 1.5:1. After a 28-day treatment period, the safety and tolerability of switching was evaluated. Due to the exploratory nature of this trial, the effects of rotigotine on motor and nonmotor symptoms of PD were analyzed in a descriptive manner.</p> <p>Results</p> <p>Of the 116 subjects who received at least one treatment, 99 (85%) completed the 28-day trial period. Dose adjustments were required for 11 subjects who completed the treatment period. A total of 76 treatment-emergent adverse events (AEs) occurred in 45 subjects. No subject experienced a serious AE. Thirteen subjects discontinued rotigotine prematurely due to AEs. Efficacy results suggested improvements in both motor and nonmotor symptoms and quality of life after switching. Fifty-two subjects (46%) agreed that they preferred using the patch over oral medications, while 31 (28%) disagreed.</p> <p>Conclusions</p> <p>Switching treatment overnight from oral ropinirole to transdermal rotigotine patch, using a dosage ratio of 1.5:1, was well tolerated in Korean patients with no loss of efficacy.</p> <p>Trial registration</p> <p>This trial is registered with the ClincalTrails.gov Registry (<a href="http://www.clinicaltrials.gov/ct2/show/NCT00593606">NCT00593606</a>).</p

Performance Analysis of Space-Time Block Codes in Flat Fading MIMO Channels with Offsets

We consider the effect of imperfect carrier offset compensation on the performance of space-time block codes. The symbol error rate (SER) for orthogonal space-time block code (OSTBC) is derived here by taking into account the carrier offset and the resulting imperfect channel state information (CSI) in Rayleigh flat fading MIMO wireless channels with offsets.https://doi.org/10.1155/2007/3054