Avaliação do efeito da adubação NPK no crescimento de gravioleira (Annona muricata L.) nas condições edafoclimáticas do município de São Francisco do Pará.

In: FRAZÃO, D. A. C.; HOMMA, A. K. O; VIÉGAS, I. de J. M. (Ed.). Contribuição ao desenvolvimento da fruticultura na Amazônia. Belém, PA: Embrapa Amazônia Oriental, 2006. p. 557-561

Determination of tetracycline and its major degradation products by liquid chromatography with fluorescence detection

A liquid chromatographic method of tetracycline and its major degradation products on a C8-reversed phase column with acidic mobile phase and fluorescence detection is described. The quantification limit, measured as the amount of sample that gave a signal ten times the peak-to-peak noise of the baseline, was: 0.25 ng for tetracycline (TC) and epitetracycline (ETC), 25 ng for and 4-epianhydrotetracycline (EATC) and 50 ng for anhydrotetracycline (ATC) of injected standard. By means of this liquid chromatography (LC) assay TC, ETC, EATC and ATC as main degradation products of tetracycline, can be separated and determined with good sensitivity and specificity within 15 min.http://www.sciencedirect.com/science/article/B6TGX-43HVHWC-1D/1/9763379e028400de01242a673bd4528

AUTOMATED COLLECTION OF QUALITY-OF-LIFE DATA: TOUCH-SCREEN COMPUTER SYSTEMS IN PATIENTS WITH IMMUNE DISEASES

AUTOMATED COLLECTION OF QUALITY-OF-LIFE DATA: TOUCH-SCREEN COMPUTER SYSTEMS IN PATIENTS WITH IMMUNE DISEASES Claúdia Ribeiro1,2,3, Augusta Silveira4,3, Isabel Silva4, Catarina Ribeiro4, Carlos Vasconcelos2,3 1UCP, 2HSA/CHP, 3ICBAS/UP, 4UFP e 5HSMF. Universidade Católica Portuguesa (UCP), Porto. Hospital de Santo António, Centro Hospitalar do Porto (HSA/CHP), Porto. Instituto Ciências Biomédicas Abel Salazar, Universidade do Porto (ICBAS/UP), Porto. Universidade Fernando Pessoa (UFP), Porto. Hospital Santa Maria da Feira (HSMF), Porto. Background The increase of technological knowledge and methodology has allowed the practice of redirecting epidemiological research, particularly in the field of chronic disease. Although capable of controlling the accumulation of events and constraints imposed by the treatment can lead to a drastic change in quality of life (QoL) of subjects progressed to varying degrees of disability and death. In this perspective the Quality of Life Related to Health (HRQOL) has taken a leading role and its evaluation is indispensable in Medicine. Aim The aims of this study were (1) analyze the importance of HRQOL assessment as a tool for health promotion and a way of measuring the effectiveness of interventions in daily practice in patients with coexisting chronic immune system (PCSI), (2) evaluation of alternative methods for the automated collection of data on HRQOL and development of an electronic interface in sample of 320 patients, (3) creating a database to ascertain the epidemiological profile of PCSI, and identification of socio-economic, demographic and clinical data of these individuals, (4) using the QoL indicator as a predictor in decision treatment and use the preferences of patients. Methods A total of 473 patients with chronic diseases of the immune system, which were applied Graffar Index, SF-36v2, a demographic questionnaire and identification of clinical variables. Results The results of this investigation suggest that the demographic, socio-economic and clinics are associated with significant differences in QoL cumulative and chronic complications associated with different pathologies. The results verified the existence of significant correlations between the different diagnoses, duration of disease and therapy. In general, patients who have chronic diseases of the immune system such as rheumatoid arthritis, lupus, scleroderma, Bechet's disease, Sjögren's syndrome or infection with human immunodeficiency virus 1 or 2 showed a worse QoL than the general population. The derivations of preferences from the SF-36v2 exhibit strong correlations with the preferences measured with the SF-6D. Conclusions This suggests that both the application of the SF-36v2 as the SF-6D can be important sources of preferences to implement measures in economic evaluation in healthcare. HRQL can and should be integrated into immune clinical practice. The translation of graphical results given to the clinician at the beginning of the consultation, favors the rapid analysis of global values of the patient's HRQL. This assessment can be an excellent diagnostic tool to be used routinely in clinical practice or assisting in disease management and therapeutic decision making. Apresentador: Cláudia Ribeiro, Médica Dentista. Doutoranda, Faculdade de Medicina da Universidade de Santiago de Compostela

Cobrição de porcas em lactação: experiência em uma criação comercial.

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AUTOMATED COLLECTION OF QUALITY-OF-LIFE DATA: TOUCH-SCREEN COMPUTER SYSTEMS IN PATIENTS WITH IMMUNE DISEASES

AUTOMATED COLLECTION OF QUALITY-OF-LIFE DATA: TOUCH-SCREEN COMPUTER SYSTEMS IN PATIENTS WITH IMMUNE DISEASES Claúdia Ribeiro1,2,3, Augusta Silveira4,3, Isabel Silva4, Catarina Ribeiro4, Carlos Vasconcelos2,3 1UCP, 2HSA/CHP, 3ICBAS/UP, 4UFP e 5HSMF. Universidade Católica Portuguesa (UCP), Porto. Hospital de Santo António, Centro Hospitalar do Porto (HSA/CHP), Porto. Instituto Ciências Biomédicas Abel Salazar, Universidade do Porto (ICBAS/UP), Porto. Universidade Fernando Pessoa (UFP), Porto. Hospital Santa Maria da Feira (HSMF), Porto. Background The increase of technological knowledge and methodology has allowed the practice of redirecting epidemiological research, particularly in the field of chronic disease. Although capable of controlling the accumulation of events and constraints imposed by the treatment can lead to a drastic change in quality of life (QoL) of subjects progressed to varying degrees of disability and death. In this perspective the Quality of Life Related to Health (HRQOL) has taken a leading role and its evaluation is indispensable in Medicine. Aim The aims of this study were (1) analyze the importance of HRQOL assessment as a tool for health promotion and a way of measuring the effectiveness of interventions in daily practice in patients with coexisting chronic immune system (PCSI), (2) evaluation of alternative methods for the automated collection of data on HRQOL and development of an electronic interface in sample of 320 patients, (3) creating a database to ascertain the epidemiological profile of PCSI, and identification of socio-economic, demographic and clinical data of these individuals, (4) using the QoL indicator as a predictor in decision treatment and use the preferences of patients. Methods A total of 473 patients with chronic diseases of the immune system, which were applied Graffar Index, SF-36v2, a demographic questionnaire and identification of clinical variables. Results The results of this investigation suggest that the demographic, socio-economic and clinics are associated with significant differences in QoL cumulative and chronic complications associated with different pathologies. The results verified the existence of significant correlations between the different diagnoses, duration of disease and therapy. In general, patients who have chronic diseases of the immune system such as rheumatoid arthritis, lupus, scleroderma, Bechet's disease, Sjögren's syndrome or infection with human immunodeficiency virus 1 or 2 showed a worse QoL than the general population. The derivations of preferences from the SF-36v2 exhibit strong correlations with the preferences measured with the SF-6D. Conclusions This suggests that both the application of the SF-36v2 as the SF-6D can be important sources of preferences to implement measures in economic evaluation in healthcare. HRQL can and should be integrated into immune clinical practice. The translation of graphical results given to the clinician at the beginning of the consultation, favors the rapid analysis of global values of the patient's HRQL. This assessment can be an excellent diagnostic tool to be used routinely in clinical practice or assisting in disease management and therapeutic decision making. Apresentador: Cláudia Ribeiro, Médica Dentista. Doutoranda, Faculdade de Medicina da Universidade de Santiago de Compostela

HEALTH-STATE UTILITIES IN CHRONIC IMMUNE DISEASES: PILOT STUDY

HEALTH-STATE UTILITIES IN CHRONIC IMMUNE DISEASES: PILOT STUDY Claúdia Ribeiro1,2,3, Augusta Silveira4,3, Augusta Marques5, Catarina Ribeiro4, Isabel Santos6,2,3, Carlos Vasconcelos2,3 1UCP, 2HSA/CHP, 3ICBAS/UP, 4UFP, 5HPA e 6HSMF. Universidade Católica Portuguesa (UCP), Porto Hospital de Santo António, Centro Hospitalar do Porto (HSA/CHP), Porto. Instituto Ciências Biomédicas Abel Salazar, Universidade do Porto (ICBAS/UP), Porto. Universidade Fernando Pessoa (UFP), Porto. Hospital Privado da Arrábida (HPA), Porto. Hospital Santa Maria da Feira (HSMF), Porto. Background Utility scores are used to estimate Quality Adjusted Life Years (QALYs), applied in determining the cost-effectiveness of health care interventions. In studies where no preference based measures are collected, indirect methods have been developed to estimate utilities from clinical instruments. Aim The aim of this study was to evaluate a published method of estimating the Short Form-6D (SF-6D) (preference based) in patients with chronic immune diseases from Unidade de Imunologia Clínica do Hospital de Santo António - Centro Hospitalar do Porto and evaluate the impact of socio demographics economics and clinical characteristics on quality of life (QoL) and potential predictors for QoL improvements. Methods We enrolled 320 patients with chronic immune diseases (104 men and 226 women with a mean age: 45.21; 84 people living with HIV and 236 with chronic autoimmune diseases. All responders to the Portuguese SF-36 version 2.0 questionnaire can be assigned an SF-6D score provided the 11 items used in the SF-6D have been completed using a computerized administration. To assess socioeconomic status, we use the Graffer’s scale, clinical and demographic variables were assessed by a questionnaire specifically designed for the present study. Results The mean utility value was .595. Male, gender, young, single, individuals with high educational attainment level and Graffer’s scale Class high reported higher utility levels. As expected, those who takes therapeutics’ or have a higher length disease reported lower mean utility levels than those who were in a less severe stadium of the disease or without therapeutic. Conclusion This paper provides the first utilities obtained from a populations leave with chronic immune diseases. The preference-based measures used in this study distinguish patient groups with chronic immune diseases’ in terms of socio-demographics characteristics and clinical groups. The normative values can be used economic evaluation and clinical studies as they incorporate patient’s preferences and translate the value attribute to patients´ health state. Apresentador: Cláudia Ribeiro, Médica Dentista. Doutoranda, Faculdade de Medicina da Universidade de Santiago de Compostela

Genetic evaluation for productive traits in endangered Portuguese Malhado de Alcobaça pig

Malhado de Alcobaça (MA) is a swine breed from center west Portugal, recognized in 2003. Herdbook (LGMA) has information of >17,000 animals (1985-2022). It´s a very endangered breed with only 244 sows, 18 boars and 12 breeders. Within the scope of MA’s genetic conservation plan, for genetic evaluation, genetic parameters and fixed effects were estimated for birth weight (PN), for adjusted weight at 30 d (P30) and at 90 d (P90). Pedigree records (n=16,883) and weighing records (nPN=9,198; nP30=5,799; nP90=2,429) from LGMA of 362 litters were compiled. Genetic parameters and fixed effects, genetic values and precisions were predicted for PN, P30 and P90, through BLUP, with a mixed model including fixed effects of breeder × year of birth, season of birth, sex, age of mother (linear / quadratic effect) and as random effects genetic value of animal, maternal genetic effect and permanent environmental effect of litter. Fixed effects of prolificacy and number of weaned piglets were included as covariates, respectively, in PN and P30/P90 analyses. Mean values for PN 1.32±0.28 kg, 7.16±1.6 kg P30 and 34.1±6.4 kg P90 were recorded. For PN, P30 and P90, respectively, a heritability for direct effects of 0.170±0.156, 0.145±0.161 and 0.293±0.175; a maternal heritability of 0.084±0.109, 0.124±0.173 and 0.250±0.186 and a genetic correlation between direct and maternal effects of -0.344, -0.524 and -0.174 was estimated. Permanent environmental effect of litter was 0.395±0.056 PN, 0.403±0.086 P30 and 0.129±0.047 P90. In fixed effects, a superiority was observed for males of +0.031 kg PN, +0.046 kg P30 and +0.201 P90. Breeder × year effect showed maximum differences of 0.93, 5.21 and 19.25 kg for PN, P30 and P90, respectively, with Spring being the best season of birth. Sow age at farrowing had a quadratic effect for all traits. For each increase of 1 piglet in prolificacy, PN, P30 and P90 were reduced by 4, 7 and 58 g, respectively.info:eu-repo/semantics/publishedVersio

Efficiency Improvement and Analysis of Changes in Microstructure Associated to a Uniform Pressure Actuator

During the 1st international Conference on HIGH SPEED FORMING held in Dortmund in 2004 a new forming coil giving significant advantages was presented in the framework of ongoing R&D programs at OSU (The Ohio State University). It established the improvement provided by the return path for currents induced in the workpiece. To quantify the mentioned improvement, Labein has performed classical cone forming experiments with both configurations and analyzed energetic efficiency using well known alloys, more precisely AA 6016 and 1050. Both deformation mechanisms and contour analysis of the specimens were studied. General purpose multi-turn coils provide pressure distributions not extended to the whole forming area, resulting in zones undergoing significant delay as die the deformation sequence is referred. As a result, varied deformation patterns can be found along the contour of a cone specimen formed in such way. Firstly, a macroscopic survey of the specimens shows that uniform pressure distributes deformation over the entire formed area during the deformation process. Secondly, the effect on efficiency provided by this new coil concept is focuses not only on the ability for distributing deformation, but on the energy required to create such deformation. Finally, to validate the whole simulation, the predicted strain level, shape, and internal energy of the workpiece are compared with the experimental specimens. A key point in the validation process is checking the internal energy. It is known that the ratio of stored energy to deformation energy ranges in the order of 30 %. The procedure for the experiments follows this methodology

Classical and quantum wormholes in a flat Λ\Lambda-decaying cosmology

We study the classical and quantum wormholes for a flat {\it Euclidean} Friedmann-Robertson-Walker metric with a perfect fluid including an ordinary matter source plus a source playing the role of dark energy (decaying cosmological term). It is shown that classical wormholes exist for this model and the quantum version of such wormholes are consistent with the Hawking-Page conjecture for quantum wormholes as solutions of the Wheeler-DeWitt equation.Comment: 8 pages, 4 figures, accepted for publication in IJT