3,483 research outputs found
Efficient Video Indexing on the Web: A System that Leverages User Interactions with a Video Player
In this paper, we propose a user-based video indexing method, that
automatically generates thumbnails of the most important scenes of an online
video stream, by analyzing users' interactions with a web video player. As a
test bench to verify our idea we have extended the YouTube video player into
the VideoSkip system. In addition, VideoSkip uses a web-database (Google
Application Engine) to keep a record of some important parameters, such as the
timing of basic user actions (play, pause, skip). Moreover, we implemented an
algorithm that selects representative thumbnails. Finally, we populated the
system with data from an experiment with nine users. We found that the
VideoSkip system indexes video content by leveraging implicit users
interactions, such as pause and thirty seconds skip. Our early findings point
toward improvements of the web video player and its thumbnail generation
technique. The VideSkip system could compliment content-based algorithms, in
order to achieve efficient video-indexing in difficult videos, such as lectures
or sports.Comment: 9 pages, 3 figures, UCMedia 2010: 2nd International ICST Conference
on User Centric Medi
Isobaric vapor−liquid equilibrium data for binary system of glycerol ethyl acetal and acetonitrile at 60.0 kPa and 97.8 kPa
Isobaric vapor−liquid equilibrium (VLE) data for the
binary mixture of glycerol ethyl acetal (GEA) and acetonitrile were measured at 60.0 kPa and 97.8 kPa, using a dynamic recirculating still. The VLE data were correlated using the nonrandom two-liquid (NRTL) and universal quasichemical activity coefficient (UNIQUAC) models, and the
interaction parameters of this mixture were estimated. The experimental procedure was checked by measuring VLE data at 97.8 kPa of the well known system acetone/methanol showing high conformity, as given by applying a set of VLE consistency tests. The vapor pressure of GEA was
measured, for the first time, in the temperature range from 371.85 K to 456.85 K, and it is described by the following expression: ln PGEA sat (Pa) =
24.17 − 5781/T(K). The information collected is of utmost importance for the purification of GEA synthesized using simulated moving bed reactor technology
Sustained gene expression in the retina by improved episomal vectors
Gene and cellular therapies are nowadays part of therapeutic strategies for the treatment of diverse pathologies. The drawbacks associated with gene therapy-low levels of transgene expression, vector loss during mitosis, and gene silencing-need to be addressed. The pEPI-1 and pEPito family of vectors was developed to overcome these limitations. It contains a scaffold/matrix attachment region, which anchors its replication to cell division in eukaryotic cells while in an extrachromosomal state and is less prone to silencing, due to a lower number of CpG motifs. Recent success showed that ocular gene therapy is an important tool for the treatment of several diseases, pending the overcome of the aforementioned limitations. To achieve sustained gene delivery in the retina, we evaluated several vectors based on pEPito and pEPI-1 for their ability to sustain transgene expression in retinal cells. These vectors stably transfected and replicated in retinal pigment epithelial (RPE) cells. Expression levels were promoter dependent with constitutive promoters cytomegalovirus immediate early promoter (CMV) and human CMV enhancer/human elongation factor 1 alpha promoter yielding the highest levels of transgene expression compared with the retina-specific RPE65 promoter. When injected in C57Bl6 mice, transgene expression was sustained for at least 32 days. Furthermore, the retina-specific RPE65 promoter showed higher efficiency in vivo compared to in vitro. In this study, we demonstrate that by combining tissue-specific promoters with a mitotic stable system, less susceptible to epigenetic silencing such as pEPito-based plasmids, we can achieve prolonged gene expression and a sustained therapeutic effect.Fundacao para a Ciencia e Tecnologia, Portugal [PEst/OE/EQB-LA 0023/2013, SFRH/BD/76873/2011, SFRH/BD/70318/2010, PTDC/SAU/BEB/098475/2008]; European Union [PIRG-GA-2009-249314
Thermodynamics of the S=1 spin ladder as a composite S=2 chain model
A special class of S=1 spin ladder hamiltonians, with second- neighbor
exchange interactions and with anisotropies in the -direction, can be mapped
onto one-dimensional composite S=2 (tetrahedral S=1) models. We calculate the
high temperature expansion of the Helmoltz free energy for the latter class of
models, and show that their magnetization behaves closely to that of standard
XXZ models with a suitable effective spin , such that
, where refers to the
components of spin in the composite model. It is also shown that the specific
heat per site of the composite model, on the other hand, can be very different
from that of the effective spin model, depending on the parameters of the
hamiltonian.Comment: 17 pages, 4 figures. Submitted for publicatio
Influence of availability of shade on testicular characteristics of Santa Ines rams
The purpose of this study was to evaluate the effects of availability of artificial shading on
testicular and seminal characteristics of Santa Ines crossbred rams. Twelve 8 month old rams at 38.1 ± 5.2 kg
average weight, were used in a total random design with two treatments: areas with and without available artificial
shading (black polyethylene mesh screen for a 50% reduction of solar radiation). The scrotal circumference,
scrotal length, scrotal volume, rectal temperature and scrotal temperature were measured twice a week. Also a
biweekly analysis of the semen was carried out, measuring the volume and spermatic concentration as well as the
percentage of normal spermatozoa. The results show that available shading provided for lower scrotal
temperatures and higher sperm concentration, without influencing the scrotal volume and the percentage of
normal spermatozoa. The testicular measures, such as the scrotal circumference and length were higher in the
rams that were subjected to the no available shading treatment. The absence of differences, in some of the
analyzed variables, between the two treatments, with and without available shading, could be due to high
adaptability of the animals
Results of the MRI substudy of the intravenous magnesium efficacy in stroke trial
<p><b>Background and Purpose:</b>Although magnesium is neuroprotective in animal stroke models, no clinical benefit was confirmed in the Intravenous Magnesium Efficacy in Stroke (IMAGES) trial of acute stroke patients. The Magnetic
Resonance in IMAGES (MR IMAGES) substudy investigated the effects of magnesium on the imaging surrogate
outcome of infarct growth.</p>
<p><b>Methods:</b> IMAGES trial patients in participating centers were randomized to receive either intravenous magnesium or placebo within 12 hours of stroke onset. Infarct growth was defined as volume difference between baseline diffusion-weighted imaging and day 90 fluid-attenuated inversion recovery image lesions. Patients who died were imputed the largest infarct growth observed.</p>
<p><b>Results:</b> Among the 90 patients included in the primary analysis, there was no difference in infarct growth (median absolute growth, P=0.639; median percentage growth, P=0.616; proportion with any growth, P=0.212) between the
46 treated with magnesium and 44 with placebo. Infarct growth correlated with NIHSS score change from baseline to
day 90. There was a trend showing baseline serum glucose correlated with infarct growth with magnesium treatment,
but not in the placebo group. The mismatch frequency was reduced from 73% to 47% by increasing the mismatch
threshold from >20% to >100% of core volume.</p>
<p><b>Conclusions:</b> Infarct growth, confirmed here as a surrogate for clinical progression, was similar between magnesium and placebo treatment, paralleling the main IMAGES trial clinical outcomes. Glucose was a covariate for infarct growth with magnesium treatment. A more stringent mismatch threshold to define penumbra more appropriately would have
excluded half of the patients in this 12-hour time window stroke study.</p>
Coupled PermSMBR – Process design and development for 1,1-dibutoxyethane production
AbstractIn this work, a new configuration of the simulated moving bed membrane reactor (PermSMBR) technology is presented, the coupled PermSMBR, where the tubular membranes are located after fixed-bed columns packed with the catalyst/adsorbent. By this way the membranes are not in contact with the solid, which from an industrial point of view is easier to implement since the process of membranes installation/replacement and clean-up is simpler than in the previous considered set-up (tubular membranes packed with the catalyst/adsorbent – integrated PermSMBR). The 1,1-dibutoxyethane production is used, as an example, and the features of the new “coupled PermSMBR” and the previous set-up (integrated PermSMBR) are discussed. The coupled PermSMBR revealed to be a very attractive solution for the sustainable 1,1-dibutoxyethane production, proved by the high productivity and low desorbent consumption obtained within the studied conditions
Hacia un cambio en la concepción de movimiento de estudiantes de la secundaria: un experimento en clase Primera Parte
The main objective of this work was to investigate the effectivinees and the didactic implications arising from the utilization of a constructivist approach to the teaching of the inertial conception of movement to a regular class of a brazilian secondary school.</p
Acoutic-oceanographic buoy - An easily deployable, reconfigurable, and multifunctional acoustic-oceanographic system
The concept of an easy to use and easy to deploy ocean acoustic tomographic (OAT) system is presented. The system is composed of a network of buoys and a data inversion online processor. This study concerns the individual node of that network—the acoustic-oceanographic buoy (AOB)—the data inversion technique and the testing of the system at sea. The AOB is a lightweight surface buoy with a vertical array of acoustic and temperature sensors to be hand deployed in a free-drifting configuration from a small boat. The data are locally stored and transmitted online to a remote station for processing and monitoring. Data inversion is based on a broadband matched-field tomography technique where known and unknown parameters are simultaneously searched for (focalization). In situ recorded temperature data serve for algorithm initialization and calibration. The AOB was successfully deployed in several consecutive days during two rapid environmental assessment sea trials in 2003 (Mediterranean) and 2004 (Atlantic). Data collected at sea also show that the AOB can be reconfigured as a receiving array for underwater coherent communications in the band up to 15 kHz
Nonequilibrium fluctuations of a remodeling in vitro cytoskeleton
Motor proteins actively contract the actin cytoskeleton of cells and thereby give rise to nonequilibrium fluctuations as well as changes in the architecture of the cytoskeleton. Here, we show, by video microrheology of a reconstituted cytoskeleton, that motors generate time-dependent nonequilibrium fluctuations, which evolve as the network is remodeled. At earlier times, the fluctuation spectrum is dominated by strong non-Gaussian fluctuations, which arise from large displacements. At later times, directed displacements are infrequent and finally disappear. We show that these effects are due to contractile coarsening of the network into large actin-myosin foci. © 2012 American Physical Society
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