Primary Ciliary Dyskinesia and Hydrocephalus With Aqueductal Stenosis

We report 1 female patient with situs inversus, dextrocardia, a complex heart malformation, hydrocephalus due to aqueductal stenosis, and abnormal ultrastructure of the respiratory epithelium cilia. Several animal models of this disorder implicate abnormal ciliary function in the genesis of hydrocephalus, and 11 patients were previously reported with hydrocephalus and the syndrome of primary ciliary dyskinesia. primary ciliary dyskinesia–associated aqueductal stenosis should be considered as a possible cause for fetal or neonatal hydrocephalus if heterotaxy, heart malformations, and/or a probable genetic etiology are present

Spatial metrics to study urban patterns in growing and shrinking cities

This article reviews existing literature on spatial metrics, presenting a portfolio of metrics addressing the spatial patterns of growing and shrinking cities and discussing their potential and limitations. A wide and diverse set of spatial metrics was found. While these metrics address most of the identified spatial patterns of urban growth, spatial metrics used in urban shrinkage studies are much scarcer and not nearly sufficient to provide a comprehensive assessment of its spatial patterns. The article concludes that there is great potential for the development of new spatial metrics or mixed indicators, particularly in shrinkage contexts. The article builds on recent literature focusing on reviewing and developing metrics for particular spatial patterns (notably patterns of urban sprawl), while considering a very broad and multidisciplinary set of metrics. It focuses not only on the outcomes of urban growth but also on those of the increasingly common shrinking phenomenon.This research was funded by the Portuguese Foundation for Science and Technology (SFRH/BD/71970/2010), co-financed by the European Social Fund through the POPH Programme.This is the author accepted manuscript. The final version is available from Taylor & Francis via http://dx.doi.org/10.1080/02723638.2015.109611

Monitorização da Adesão à Terapêutica Médica do Glaucoma

Introdução: A adesão à terapêutica antiglaucomatosa é fundamental na redução e controlo da pressão intra-ocular. O glaucoma, por ser uma doença crónica e inicialmente assintomática, tem um risco aumentado de não cumprimento terapêutico. Este estudo tem como objectivo a avaliação da adesão à terapêutica médica do glaucoma (estrita e relativa), através da utilização de um dispositivo de registo electrónico (DRE). Material e Métodos: Estudo prospectivo que incluiu 21 doentes, com glaucoma ou hipertensão ocular. Um e três meses após a visita inicial, procedeu-se ao preenchimento de um questionário relativo à compliance e analisaram-se os dados registados no DRE. Resultados: A idade média dos doentes era 62,4 anos (± 19,2), 52% do sexo masculino e 48% do sexo feminino. A compliance média relativa foi de 77,9% no primeiro mês e de 78,7% no final do terceiro mês. A compliance média estrita foi de 56,7% e de 53.3% no final do primeiro e terceiro mês, respectivamente. A maioria dos doentes sentiu facilidade (80,9%) e deseja continuar (85,7%) a utilização do mesmo. Conclusão: A adesão à terapêutica médica do glaucoma, factor importante no controlo desta patologia, pode ser avaliada de forma simples e objectiva através da utilização de um dispositivo de registo electrónico

Natural nanomaterials : reappraising the elusive structure of the nano-sized mineral ferrihydrite through X-Ray absorption spectroscopy at the iron K-edge

Ferrihydrite is natural ferric oxyhydroxide occurring exclusively nanocrystalline. With ideal formula 5 Fe2 O3 . 9 H2 O, ferrihydrite is quite abundant in sediments, weathering crusts and mine wastes, being characteristic of red pre-soils formed by loose weathered rock plus mineral debris (regoliths) and commonly designated as “2-line” or “6-line” on the basis of the broadened maxima observed in the X-ray diffraction pattern. Synthetic nanocrystalline “6-line” ferrihydrite was recently studied through methods based on atomic-pair distribution functions disclosing the possible occurrence of icosahedral clusters formed by twelve octahedra centred by an inner tetrahedron, all filled by Fe 3+ ions. However, Mössbauer studies were inconclusive about the existence of 4-coordinated iron, thus suggesting that the tetrahedral cation may well be Si4+. In view of such structural uncertainty, a XANES study at the Fe K-edge was undertaken on ferrihydrite from a regolith to ascertain the occurrence of tetrahedral iron. Comparison with data collected from well crystallized iron oxide and hydroxide minerals where Fe 3+/2+ ions occur in octahedral and tetrahedral coordination is described and the results so far obtained are discussed, showing that supplementary study is needed on the elusive structure of ferrihydrite

Importance of Cutaneous Changes in the Diagnosis of Neurological Diseases

info:eu-repo/semantics/publishedVersio

Cultural Heritage analysis using Synchrotron Radiaon: case studies in Ceramics, Glasses, and Lithologic Materials

ABSTRACT: Synchrotron radiaton is a powerful tool for non‐destructve analysis of materials in cultural heritage research. It has revolutonized our ability to understand the compositon, structure, and history of cultural heritage objects, leading to significant advances in fields such as archaeology, art conservation, and materials science. Dedicated beamlines for cultural heritage research are available at synchrotron facilites around the world, such as the European Synchrotron Radiation Facility (ESRF), SOLEIL synchrotron, and ALBA synchrotron, providing specialized support and instrumentation for high‐resolution analysis of cultural heritage objects using various techniques, such as X‐ray absorption spectroscopy, X‐ray fluorescence, X‐ray diffraction, and X‐ray imaging.N/