Electrode level Monte Carlo model of radiation damage effects on astronomical CCDs

Current optical space telescopes rely upon silicon Charge Coupled Devices (CCDs) to detect and image the incoming photons. The performance of a CCD detector depends on its ability to transfer electrons through the silicon efficiently, so that the signal from every pixel may be read out through a single amplifier. This process of electron transfer is highly susceptible to the effects of solar proton damage (or non-ionizing radiation damage). This is because charged particles passing through the CCD displace silicon atoms, introducing energy levels into the semi-conductor bandgap which act as localized electron traps. The reduction in Charge Transfer Efficiency (CTE) leads to signal loss and image smearing. The European Space Agency's astrometric Gaia mission will make extensive use of CCDs to create the most complete and accurate stereoscopic map to date of the Milky Way. In the context of the Gaia mission CTE is referred to with the complementary quantity Charge Transfer Inefficiency (CTI = 1-CTE). CTI is an extremely important issue that threatens Gaia's performances. We present here a detailed Monte Carlo model which has been developed to simulate the operation of a damaged CCD at the pixel electrode level. This model implements a new approach to both the charge density distribution within a pixel and the charge capture and release probabilities, which allows the reproduction of CTI effects on a variety of measurements for a large signal level range in particular for signals of the order of a few electrons. A running version of the model as well as a brief documentation and a few examples are readily available at http://www.strw.leidenuniv.nl/~prodhomme/cemga.php as part of the CEMGA java package (CTI Effects Models for Gaia).Comment: Accepted by MNRAS on 13 February 2011. 15 pages, 7 figures and 5 table

How can healthcare workers adapt non-pharmacological treatment – whilst maintaining safety – when treating people with COVID-19 and delirium?

Delirium may be part of the spectrum of COVID-19 symptoms that patients present with. In some cases, the delirium may be severe and have a rapid onset. Clinicians should have a high level of suspicion of COVID-19 when considering a possible cause of the delirium. Non-pharmacological interventions (See Box 1) are the mainstay for the management of delirium in all settings; there is consistent evidence of benefit in the prevention of delirium Communication and care are compromised by the need for Personal Protection Equipment (PPE) in COVID-19 Use of remote consultations may be necessary and is often feasible (See Box 2

Isopoll Maps and an Analysis of the Distribution of the Modern Pollen Rain, Eastern and Central Northern Canada

At 39 sites in eastern and central northern Canada, multiple samples of surface moss and lichens have been analyzed for their pollen content. Although pollen from 20 to 30 taxa were identified in the samples from each site, 8 pollen types (Alnus, Betula, Picea. Pinus, Salix, Gramineae, Cyperaceae and Ericaceae) usually comprise 90 to 100% of the pollen rain. We present isopoll maps of these taxa based on mean percentages of multiple samples from the 39 sites. The data are further analyzed by a number of statistical methods to determine whether there are specific pollen assemblages within this region and to what extent present day climatic parameters and floristic/vegetation zones correlate with pollen counts. Cluster analysis on raw data and on principal component scores yields six distinct pollen assemblages which are further examined by discriminant analysis. Pollen concentration maps for eastern Canada are also presented here and used as an aid in interpreting the percentage data.L'analyse pollinique d'un grand nombre d'échantillons de mousses et de lichens prélevés à la surface de 39 sites du centre et de l'est du Nord canadien a été faite. Même si on a pu identifier de 20 à 30 taxons dans les échantillons provenant de chacun des sites, 8 types polliniques (Alnus, Betula, Picea, Pinus, Salix, Gramineae, Cyperaceae, Ericaceae) se partagent habituellement entre 90 et 100% de la pluie pollinique. On présente ici les cartes isopolles de ces taxons, basées sur les pourcentages moyens des nombreux échantillons prélevés sur les 39 sites. L'analyse statistique des données qui a été faite avait pour but de dégager des assemblages polliniques distincts et de déterminer si les paramètres climatiques actuels ainsi que les régions floristiques pouvaient être mis en corrélation avec les sommes polliniques. Une analyse de grappes et de scores des composantes principales et des données brutes a permis de dégager 6 assemblages polliniques distincts qui ont fait l'objet d'une analyse discriminante. Les cartes de concentration pollinique de l'est du Canada, qui ont été dressées, ont servi à l'interprétation des données en pourcentage

Can dark matter be a Bose-Einstein condensate?

We consider the possibility that the dark matter, which is required to explain the dynamics of the neutral hydrogen clouds at large distances from the galactic center, could be in the form of a Bose-Einstein condensate. To study the condensate we use the non-relativistic Gross-Pitaevskii equation. By introducing the Madelung representation of the wave function, we formulate the dynamics of the system in terms of the continuity equation and of the hydrodynamic Euler equations. Hence dark matter can be described as a non-relativistic, Newtonian Bose-Einstein gravitational condensate gas, whose density and pressure are related by a barotropic equation of state. In the case of a condensate with quartic non-linearity, the equation of state is polytropic with index $n=1$. To test the validity of the model we fit the Newtonian tangential velocity equation of the model with a sample of rotation curves of low surface brightness and dwarf galaxies, respectively. We find a very good agreement between the theoretical rotation curves and the observational data for the low surface brightness galaxies. The deflection of photons passing through the dark matter halos is also analyzed, and the bending angle of light is computed. The bending angle obtained for the Bose-Einstein condensate is larger than that predicted by standard general relativistic and dark matter models. Therefore the study of the light deflection by galaxies and the gravitational lensing could discriminate between the Bose-Einstein condensate dark matter model and other dark matter models.Comment: 20 pages, 7 figures, accepted for publication in JCAP, references adde

Filling some black holes: modeling the connection between urbanization, infrastructure, and global service intensity

This empirical article combines insights from previous research on the level of knowledge-intensive service in metropolitan areas with the aim to develop an understanding of the spatial structure of the global service economy. We use a stepwise regression model with the Globalization and World Cities research network's measure of globalized service provisioning as the dependent variable and a range of variables focusing on population, infrastructure, urban primacy, and national regulation as independent variables. The discussion of the results focuses on model parameters as well as the meaning of outliers and is used to explore some avenues for future research

Genomic Profiling Reveals Distinct Routes To Complement Resistance in Klebsiella pneumoniae.

The serum complement system is a first line of defense against bacterial invaders. Resistance to killing by serum enhances the capacity of Klebsiella pneumoniae to cause infection, but it is an incompletely understood virulence trait. Identifying and characterizing the factors responsible for preventing activation of, and killing by, serum complement could inform new approaches to treatment of K. pneumoniae infections. Here, we used functional genomic profiling to define the genetic basis of complement resistance in four diverse serum-resistant K. pneumoniae strains (NTUH-K2044, B5055, ATCC 43816, and RH201207), and explored their recognition by key complement components. More than 90 genes contributed to resistance in one or more strains, but only three, rfaH, lpp, and arnD, were common to all four strains. Deletion of the antiterminator rfaH, which controls the expression of capsule and O side chains, resulted in dramatic complement resistance reductions in all strains. The murein lipoprotein gene lpp promoted capsule retention through a mechanism dependent on its C-terminal lysine residue; its deletion led to modest reductions in complement resistance. Binding experiments with the complement components C3b and C5b-9 showed that the underlying mechanism of evasion varied in the four strains: B5055 and NTUH-K2044 appeared to bypass recognition by complement entirely, while ATCC 43816 and RH201207 were able to resist killing despite being associated with substantial levels of C5b-9. All rfaH and lpp mutants bound C3b and C5b-9 in large quantities. Our findings show that, even among this small selection of isolates, K. pneumoniae adopts differing mechanisms and utilizes distinct gene sets to avoid complement attack

From 'River Cottage' to 'Chicken Run': Hugh Fearnley-Whttingstall and the class politics of ethical consumption

Lifestyle television provides a key site through which to explore the dilemmas of ethical consumption, as the genre shifts to consider the ethics of different consumption practices and taste cultures. UK television cook Hugh Fearnley-Whittingstall's TV programmes offer fertile ground not only for thinking about television personalities as lifestyle experts and moral entrepreneurs, but also for thinking about how the meanings and uses of their television image are inflected by genre. In this article we explore how the shift from the lifestyled downshifting narrative of the River Cottage series to the 'campaigning culinary documentary' Hugh's Chicken Run exposes issues of celebrity, class and ethics. While both series are concerned with ethical consumption, they work in different ways to reveal a distinction between 'ethical' and 'unethical' consumption practices and positions - positions that are inevitably classed

Developing a framework for the analysis of power through depotentia

Stakeholder participation in tourism policy-making is usually perceived as providing a means of empowerment. However participatory processes drawing upon stakeholders from traditionally empowered backgrounds may provide the means of removing empowerment from stakeholders. Such an outcome would be in contradiction to the claims that participatory processes improve both inclusivity and sustainability. In order to form an understanding of the sources through which empowerment may be removed, an analytical perspective has been developed deriving from Lukes�s views of power dating from 1974. This perspective considers the concept of depotentia as the removal of �power to� without speculating upon the underlying intent and also provides for the multidimensionality of power to be examined within a single study. The application of this analytical perspective has been tested upon findings of the government-commissioned report of the Countryside and Community Research Unit in 2005. The survey and report investigated the progress of Local Access Forums in England created in response to the Countryside and Rights of Way Act 2000. Consideration of the data from this perspective permits the classification of individual sources of depotentia which can each be addressed and potentially enable stakeholder groups to reverse loss of empowerment where it has occurred