A new proof of some polynomial inequalities related to pseudo-splines

AbstractPseudo-splines of type I were introduced in [I. Daubechies, B. Han, A. Ron, Z. Shen, Framelets: MRA-based constructions of wavelet frames, Appl. Comput. Harmon. Anal. 14 (2003) 1–46] and [Selenick, Smooth wavelet tight frames with zero moments, Appl. Comput. Harmon. Anal. 10 (2000) 163–181] and type II were introduced in [B. Dong, Z. Shen, Pseudo-splines, wavelets and framelets, Appl. Comput. Harmon. Anal. 22 (2007) 78–104]. Both types of pseudo-splines provide a rich family of refinable functions with B-splines, interpolatory refinable functions and refinable functions with orthonormal shifts as special examples. In [B. Dong, Z. Shen, Pseudo-splines, wavelets and framelets, Appl. Comput. Harmon. Anal. 22 (2007) 78–104], Dong and Shen gave a regularity analysis of pseudo-splines of both types. The key to regularity analysis is Proposition 3.2 in [B. Dong, Z. Shen, Pseudo-splines, wavelets and framelets, Appl. Comput. Harmon. Anal. 22 (2007) 78–104], which also appeared in [A. Cohen, J.P. Conze, Régularité des bases d'ondelettes et mesures ergodiques, Rev. Mat. Iberoamericana 8 (1992) 351–365] and [I. Daubechies, Ten Lectures on Wavelets, CBMS-NSF Series in Applied Mathematics, SIAM, Philadelphia, 1992] for the case l=N−1. In this note, we will give a new insight into this proposition

PSAT1 prompted cell proliferation and inhibited cell apoptosis in multiple myeloma through regulating PI3K/AKT pathway

Purpose: To identify the biological function of phosphoserine aminotransferase 1 (PSAT1) in regulating cell proliferation and apoptosis in multiple myeloma (MM).Methods: The mRNA and protein levels of PSAT1 were determined using quantitative real-time polymerase chain reaction (PCR) and western blotting, respectively. Cell proliferation was measured using CCK-8 assay.Results: PSAT1 mRNA and protein expression levels were significantly increased in MM cell lines when compared to control cells. Moreover,  downregulation of PSAT1 inhibited MM cell proliferation and induced cell apoptosis, whereas overexpression of PSAT1 promoted MM cell  proliferation and suppressed cell apoptosis. Further analysis demonstrated that the underlying mechanism was via regulation of PI3K/AKT pathway.Conclusion: The results identified a novel role for PSAT1 in the progression of MM, which may provide a therapeutic and a new anticancer target for the therapy of MM. Keywords: Multiple myeloma, PSAT1, Cell proliferation, PI3K/AKT pathwa

This article has been accepted for inclusion in a future issue of this journal. Content is final as presented, with the exception of pagination. IEEE/ACM TRANSACTIONS ON NETWORKING 1 Design, Realization, and Evaluation of DozyAP for Power-Efficient Wi-Fi

Abstract—Wi-Fi tethering (i.e., sharing the Internet connection of a mobile phone via its Wi-Fi interface) is a useful functionality and is widely supported on commercial smartphones. Yet, existing Wi-Fi tethering schemes consume excessive power: They keep the Wi-Fi interface in a high power state regardless if there is ongoing traffic or not. In this paper, we propose DozyAP to improve the power efficiency of Wi-Fi tethering. Based on measurements in typical applications, we identify many opportunities that a tethering phone could sleep to save power. We design a simple yet reliable sleep protocol to coordinate the sleep schedule of the tethering phone with its clients without requiring tight time synchronization. Furthermore, we develop a two-stage, sleep interval adaptation algorithm to automatically adapt the sleep intervals to ongoing traffic patterns of various applications. DozyAP does not require any changes to the 802.11 protocol and is incrementally deployable through software updates. We have implemented DozyAP on commercial smartphones. Experimental results show that, while retaining comparable user experiences, our implementation can allow the Wi-Fi interface to sleep for up to 88 % of the total time in several different applications and reduce the system power consumption by up to 33 % under the restricted programmability of current Wi-Fi hardware. Index Terms—802.11, mobile hotspot, power-efficient, software access point, Wi-Fi tethering

Non-Gaussianity in the warm k-inflation

This paper presents and investigates non-Gaussian perturbations for the warm k-inflation model that is driven by pure kinetic energy. The two complementary components of the overall non-Gaussianity are the three-point and four-point correlations. The intrinsic non-Gaussian component, denoted as the nonlinear parameter f_{NL}^{int}, is rooted in the three-point correlation for the inflaton field. Meanwhile, the \delta N part non-Gaussianity, denoted as f_{NL}^{\delta N}, is the contribution attributed to the four-point correlation function of the inflaton field. In this paper, the above two components in warm k-inflation are individually computed and analyzed. Then, comparisons and discussions between them are conducted, and the non-Gaussian theoretical results are compared with experimental observations to determine the range of model parameters within the allowable range of observation

A genetic diversity assessment of starch quality traits in rice landraces from the Taihu basin, China

AbstractThere are nearly 1000 rice landrace varieties in the Taihu basin, China. To assess the genetic diversity of the rice, 24 intragenic molecular markers (representing 17 starch synthesis-related genes) were investigated in 115 Taihu basin rice landraces and 87 improved cultivars simultaneously. The results show that the average genetic diversity and polymorphism information content values of the landraces were higher than those of improved cultivars. In total, 41 and 39 allele combinations (of the 17 genes) were derived from the landraces and improved cultivars, respectively; only two identical allele combinations were found between the two rice variety sources. Cluster analysis, based on the molecular markers, revealed that the rice varieties could be subdivided into five groups and, within these, the japonica improved rice and japonica landrace rice varieties were in two separate groups. According to the quality reference criteria to classify the rice into grades, some of the landraces were found to perform well, in terms of starch quality. For example, according to NY/T595-2002 criteria from the Ministry of Agriculture of China, 25 and 33 landraces reached grade 1, in terms of their apparent amylose content and gel consistency. The varieties that had outstanding quality could be used as breeding materials for rice quality breeding programs in the future. Our study is useful for future applications, such as genetic diversity studies, the protection of rice variety and improvment of rice quality in breeding programs

Microbiology, ecology, and application of the nitrite-dependent anaerobic methane oxidation process

Nitrite-dependent anaerobic methane oxidation (n-damo), which couples the anaerobic oxidation of methane to denitrification, is a recently discovered process mediated by “Candidatus Methylomirabilis oxyfera.” M. oxyfera is affiliated with the “NC10” phylum, a phylum having no members in pure culture. Based on the isotopic labeling experiments, it is hypothesized that M. oxyfera has an unusual intra-aerobic pathway for the production of oxygen via the dismutation of nitric oxide into dinitrogen gas and oxygen. In addition, the bacterial species has a unique ultrastructure that is distinct from that of other previously described microorganisms. M. oxyfera-like sequences have been recovered from different natural habitats, suggesting that the n-damo process potentially contributes to global carbon and nitrogen cycles. The n-damo process is a process that can reduce the greenhouse effect, as methane is more effective in heat-trapping than carbon dioxide. The n-damo process, which uses methane instead of organic matter to drive denitrification, is also an economical nitrogen removal process because methane is a relatively inexpensive electron donor. This mini-review summarizes the peculiar microbiology of M. oxyfera and discusses the potential ecological importance and engineering application of the n-damo process

The Association and Clinical Significance of CDKN2A Promoter Methylation in Head and Neck Squamous Cell Carcinoma: a Meta-Analysis

Background/Aims: The association between cyclin-dependent kinase inhibitor 2A (CDKN2A) hypermethylation and head and neck squamous cell carcinoma (HNSCC) risk has been investigated by a number of studies. However, these studies have not demonstrated consistent results. Moreover, the role of CDKN2A methylation in HNSCC carcinogenesis and its clinical significance remain unclear. Methods: We performed a systematic meta-analysis based on 72 articles (including 3399 HNSCCs, 668 premalignant lesions, and 2393 normal controls) from the PubMed, Google Scholar, Web of Science, Embase, China National Knowledge Infrastructure and Wanfang databases. Results: Our study showed a significant increase in the frequency of CDKN2A methylation during HNSCC carcinogenesis (HNSCC vs. normal controls, odds ratio (OR) = 6.72, P < 0.01; HNSCC vs. precancerous lesions, OR = 1.89, P < 0.05; precancerous lesions vs. normal controls, OR = 14.70, P < 0.01). Moreover, CDKN2A methylation was significantly associated with gender (OR = 1.34; P < 0.05) and lymph node metastasis (OR = 2.32; P < 0.01). The area under summary receiver operating characteristic curve (AUC) for diagnosis of HNSCC based on all samples and saliva sample subgroup were 0.77 and 0.96, respectively. Additionally, CDKN2A hypermethylation was significantly associated with shorter overall survival (OS) (hazard ratio (HR) = 1.01, P < 0.05) and recurrence-free survival (RFS) (HR = 1.77, P < 0.05). Conclusion: Our findings indicate CDKN2A methylation is involved in the carcinogenesis, progression, and metastasis of HNSCC. Furthermore, methylated CDKN2A could be a potential diagnostic and prognostic biomarker for HNSCC