273 research outputs found

    A case series of Stener’s lesion of the first metacarpophalangeal joint

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    Ulnar collateral ligament (UCL) injuries have a high prevalence however; these are usually being missed in the initial clinical evaluation. Depending on the chronicity of the injury there are two acronyms for UCL tear. One is the skier's thumb and the other is the gamekeeper's thumb. If the UCL of the first metacarpophalangeal joint (MCP joint) has a complete tear with entrapment of aponeurosis of adductor pollicis muscle between the MCP joint and torn ligament, is called a Stener’s lesion. This is a rare clinical entity that requires early surgical correction because of entrapment. The mechanism of injury is the coerced abduction of the thumb from the index finger, causing ligament tears or sprain with or without ensuing avulsion fracture. The incidence of Stener’s lesions associated with UCL rupture has been reported to be up to 52% per intra-operative finding. In Stener’s lesions, the UCL tears from the base of the proximal phalanx (PP) then retracts proximally and displaces superficial to the adductor pollicis. Here we are presenting four cases of Stener’s lesions, with the usefulness of magnetic resonance imaging (MRI) in diagnosing this entity, which can prevent possible long-term complications such as chronic pain, joint degeneration, and joint instability

    BIOCHEMICAL CHANGES IN THE STORED WHOLE BLOOD ASSESSED AT PERIODIC INTERVALS IN CPDA-1 ANTICOAGULANT CONTAINING BLOOD BAGS: A STUDY AT THE BLOOD BANK OF TERTIARY CARE HOSPITAL OF SOUTHERN RAJASTHAN

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    Objectives: The objectives of this study were to study the various biochemical changes occurring in a stored whole blood unit at day 0, day 17th, and the 35th day in full blood bag containing citrate phosphate dextrose adenine-1 anticoagulant. Methods: A cross-sectional descriptive study had been carried out among 110 healthy volunteer donors in the Department of Transfusion Medicine, RNT Medical College, Udaipur, between August 2019 and July 2020. A 10 mL blood sample from each bag containing anti-coagulated blood being collected, and the level of sodium, potassium, chloride, total protein, and albumin were measured on days 0, 17th, and the 35th. Mean and standard deviation had been calculated for the parameters, a one-way analysis of variance test was applied to compare the differences, and a p<0.05 was considered statistically significant. Results: A higher proportion of males in the age group 18–27 years, and a generally steady increase in serum potassium level with a steady decrease in serum sodium, chloride, total protein, and albumin levels over the 35-day storage period. Conclusions: In this study, stored whole blood undergoing changes in its biochemical parameters had been studied and found to be significant. The study also recommends transfusion of fresh blood for high-risk patients

    Oxidized cellulose: an unusual cause of post hysterectomy hemorrhage

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    Haemostatic material made of oxidized cellulose is a bio-absorbable fabric used widely for intraoperative haemostasis and adhesion prevention in surgery. The knit mesh facilitates platelet adhesion and aggregation during surgery. However, rarely it may cause a foreign-body reaction, which is indistinguishable from abscess or granuloma formation. This report describes a case of a local tissue reaction due to oxidized regenerated cellulose followed by vault erosion and vaginal bleeding, mimicking pelvic sepsis post hysterectomy. The signs and symptoms resolved completely following removal of the oxidized cellulose fabric

    CECT IN THE ADRENOCORTICAL CARCINOMAS: RECOGNIZING THE TYPICAL MORPHOLOGICAL FEATURES

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    Objectives: This study was characterization of adrenal masses on computer tomography (CT) using shape, size, and enhancement patterns. Methods: It is a retrospective study of 86 adrenal masses with morphological differences in the appearance and enhancement patterns (histopathologically proven 36 pheochromocytoma [PCCs], 26 adrenal cortical carcinoma [ACCs], one lymphoma, 22 metastases, and one schwannoma). Two experienced radiologists who were unaware of the histopathological diagnosis reviewed the computed tomography scans, morphological parameters had been noted, along with attenuations measured in Hounsfield units for all the phases of contrast-enhanced computed tomography. Results: Necrosis had been seen in all the cases of ACCs with a loss of adeniform shape. ACCs were significantly less enhancing in arterial phase and venous phase than PCC; however, no significant difference was seen with lymphomas, metastasis, and schwannoma. 25/33 (75.5%) ACC showed heterogeneous enhancement (due to the presence of necrosis) in the VP. Conclusion: Heterogenous architecture with a size of more than 5 cm is relatively specific for diagnosing ACC. No specific enhancement pattern could well differentiate ACC from lymphoma, metastases, and schwannoma

    Nepal Himalaya Offers Considerable Potential for Pumped Storage Hydropower

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    There is a pressing need for a transition from fossil-fuel to renewable energy to meet the increasing energy demands and reduce greenhouse gas emissions. The Nepal Himalaya possesses substantial renewable energy potential that can be harnessed through hydropower projects due to its peculiar topographic characteristics and abundant water resources. However, the current exploitation rate is low owing to the predominance of run-of-river hydropower systems to support the nation's power system. The utility-scale storage facility is crucial in the load scenario of an integrated Nepalese power system to manage diurnal variation, peak demand, and penetration of intermittent energy sources. In this study, we first identify the potential of pumped storage hydropower across the country under multiple configurations by pairing lakes, hydropower projects, rivers, and available flat terrains. We then identify technically feasible pairs from those of potential locations. Infrastructural, environmental, operational, and other technical constraints govern the choice of feasible locations. We find the flat land-to-river configuration most promising over other configurations for Nepal. Our results provide insight into the potential of pumped storage hydropower and are of practical importance in planning sustainable power systems in the Himalayas

    Grzybiczy tętniak rzekomy tętnicy płucnej u pacjentki z historią ubytku przegrody międzykomorowej. Opis przypadku i przegląd piśmiennictwa

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    Tętniaki są rzadko zlokalizowane w tętnicy płucnej. Częstszą jest lokalizacja wewnątrzczaszkowa, aorta lub inne naczynia krwionośne. Tętniak tętnicy płucnej może być spowodowany zakażeniem takimi bakteriami, jak Staphylococcus, Streptococcus, Mycobacteria, Treponema pallidum, rzadziej grzybami. W pracy przedstawiono opis przypadku 7-letniej pacjentki, u której wystąpiły dwa prawostronne, przywnękowe tętniaki rzekome pochodzenia grzybiczego. Pacjentka była wcześniej leczona z powodu ubytku przegrody międzykomorowej. Grzybicze tętniaki rzekome tętnicy płucnej występują rzadko, a ich diagnostyka jest trudna. Jeśli u chorego przez dłuższy czas utrzymują się gorączka i kaszel, a zagęszczenie w obrębie miąższu płuc nie odpowiada na antybiotykoterapię, zaleca się wykonanie tomografii komputerowej klatki piersiowej z kontrastem. Można podejrzewać, że „krucha masa przyczepiona do łaty ubytku przegrody międzykomorowej” była punktem wyjścia dla rozwoju infekcyjnego zapalenia wsierdzia oraz powstania grzybiczego materiału zatorowego w tętnicach płucnych. Leczony wcześniej ubytek przegrody międzykomorowej mógł się w ten sposób przyczynić do rozwoju grzybiczego zapalenia wsierdzia.Tętniaki są rzadko zlokalizowane w tętnicy płucnej. Częstszą jest lokalizacja wewnątrzczaszkowa, aorta lub inne naczynia krwionośne. Tętniak tętnicy płucnej może być spowodowany zakażeniem takimi bakteriami, jak Staphylococcus, Streptococcus, Mycobacteria, Treponema pallidum, rzadziej grzybami. W pracy przedstawiono opis przypadku 7-letniej pacjentki, u której wystąpiły dwa prawostronne, przywnękowe tętniaki rzekome pochodzenia grzybiczego. Pacjentka była wcześniej leczona z powodu ubytku przegrody międzykomorowej. Grzybicze tętniaki rzekome tętnicy płucnej występują rzadko, a ich diagnostyka jest trudna. Jeśli u chorego przez dłuższy czas utrzymują się gorączka i kaszel, a zagęszczenie w obrębie miąższu płuc nie odpowiada na antybiotykoterapię, zaleca się wykonanie tomografii komputerowej klatki piersiowej z kontrastem. Można podejrzewać, że „krucha masa przyczepiona do łaty ubytku przegrody międzykomorowej” była punktem wyjścia dla rozwoju infekcyjnego zapalenia wsierdzia oraz powstania grzybiczego materiału zatorowego w tętnicach płucnych. Leczony wcześniej ubytek przegrody międzykomorowej mógł się w ten sposób przyczynić do rozwoju grzybiczego zapalenia wsierdzia

    Modeling diffuse reflectance from homogeneous semi-infinite turbid media for biological tissue applications: a Monte Carlo study

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    Diffuse reflectance spectroscopy is one of the simplest and widely used techniques for the non-invasive study of biological tissues but no exact analytical solution exists for the problem of diffuse reflectance from turbid media such as biological tissues. In this work, a general treatment of the problem of diffuse reflectance from a homogeneous semi-infinite turbid medium is presented using Monte Carlo simulations. Based on the results of the Monte Carlo method, simple semi-empirical analytical solutions are developed valid for a wide range of collection geometries corresponding to various optical detector diameters. This approach may be useful for the quick and accurate modeling of diffuse reflectance from tissues

    Genomic diversity among sorghum genotypes with resistance to sorghum shoot fly, Atherigona soccata

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    Host plant resistance is one of the important components for management of sorghum shoot fly, Atherigona soccata. The levels of resistance in cultivated germplasm are low to moderate, and therefore, it is important to identify sorghum genotypes with diverse mechanisms of resistance based on physico-chemical and or molecular markers. We assessed the genetic diversity of 15 sorghum genotypes with different levels of resistance/susceptibility to shoot fly, A. soccata using 93 sorghum simple sequence repeat (SSR) primer pairs and simultaneously characterized for 15 morpho-biochemical traits associated with shoot fly resistance

    SSR allelic diversity in relation to morphological traits and resistance to grain mould in sorghum

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    Allelic variation at 46 simple sequence repeat (SSR) marker loci well distributed across the sorghum genome was used to assess genetic diversity among 92 sorghum lines, 74 resistant and 18 susceptible to grain mould. Of the 46 SSR markers, 44 were polymorphic, with the number of alleles ranging from 2 to 20 with an average of 7.55 alleles per locus. Genetic diversity among the sorghum lines was high as indicated by polymorphic information content (PIC) and gene diversity values. PIC values of polymorphic SSR markers ranged from 0.16 to 0.90, with an average of 0.54. Gene diversity among the sorghum lines varied from 0.16 to 0.91, with an average score of 0.58 per SSR marker. AMOVA indicated that 12% of the total variation observed among the sorghum lines was accounted for between grain mould resistant and susceptible types. Diversity based on six morphological traits and grain mould scores indicated major roles of panicle type and glumes coverage, followed by grain colour, in clustering of the lines. Seven grain mould resistant/ susceptible pairs with dissimilarity indices >0.50, but with similar flowering time, plant height, and panicle type/ inflorescence within each pair, were selected for use in developing recombinant inbred line mapping populations to identify genomic regions (and quantitative trait loci) associated with sorghum grain mould resistance
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