659 research outputs found

    The influence of psychosocial adjustment factors on team embeddedness at the workplace

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    The high prevalence of aggression, anxiety and stress symptoms among team members in the organisation, while acquisition of task is alarming causation of adjustment disorder influences on team embeddedness, is the subject of this study. The ontogenesis of psychosocial adjustment disorder in any employees is not palingenetic, this is exact reproduction of psychosocial factors (PSF) which develops at workplace The most important strategy for productivity improvement is based on the fact that human productivity, both positive and negative, is determined by the attitudes of all those who work in the enterprise and gap surfaced between teamwork and competence development particularly with regard to managing individualism within organisation and specifically individualistic approach, organisational justice, productivity management and psychosocial support. We strongly feel that there is a need to reexamine organisational team credentials and possible strong influences on individual’s psychosocial adjustment disorders. Findings suggest psychosocial adjustment factors are significantly correlated with psychosocial disorders (PSDs)

    Teaching Students to Evaluate Evidence for Different Audiences

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    Shar Gregg, from the Department of Humanities and Communication, led this workshop designed to help faculty consider how to teach audience awareness, particularly how to select evidence for different audiences. She demonstrated frameworks for considering audiences and for approaching the use of evidence.https://digitalcommons.csumb.edu/ta_workshops/1002/thumbnail.jp

    Dual-camera infrared guidance for computed tomography biopsy procedures

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    A CT-guided biopsy is a specialised surgical procedure whereby a needle is used to withdraw tissue or fluid specimen from a lesion of interest. The needle is guided while being viewed by a clinician on a computed tomography (CT) scan. CT guided biopsies invariably expose patients and operators to high dosage of radiation and are lengthy procedures where the lack of spatial referencing while guiding the needle along the required entry path are some of the diffculties currently encountered. This research focuses on addressing two of the challenges clinicians currently face when performing CT-guided biopsy procedures. The first challenge is the lack of spatial referencing during a biopsy procedure, with the requirement for improved accuracy and reduction in the number of repeated scans. In order to achieve this an infrared navigation system was designed and implemented where an existing approach was subsequently extended to help guide the clinician in advancing the biopsy needle. This extended algorithm computed a scaled estimate of the needle endpoint and assists with navigating the biopsy needle through a dedicated and custom built graphical user interface. The second challenge was to design and implement a training environment where clinicians could practice different entry angles and scenarios. A prototype training module was designed and built to provide simulated biopsy procedures in order to help increase spatial referencing. Various experiments and different scenarios were designed and tested to demonstrate the correctness of the algorithm and provide real-life simulated scenarios where the operators had a chance to practice different entry angles and familiarise themselves with the equipment. A comprehensive survey was also undertaken to investigate the advantages and disadvantages of the system

    Cytotoxic Effects of Methylgerambullin and Bis(Methylthiomethyl)-Disulphide (SB) on T-Lymphoblastic Leukemic Cell Line (Cem-SS)

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    The cytotoxic effects of 2 sulphur-containing compounds were studied on Tlymphoblastic leukemic cell line. Methylgerambullin is believed to be a new sulphone derived from a methylthiopropenoic acid isolated from Glycosmis calcicola (family Rutaceae). Another sui phonic compound IS bis- (methylthiomethyl)-disulphide, an extract from Scorodocarpus borneensis (family Olacaceae) with irritating garlic-like odor. Cytotoxic activities of methylgerambullin and bis-(methylthiomethyl)-disulphide were tested against CEM-SS (T-Iymphoblastic leukaemia), KU812F (chronic myelogeneous leukaemia), UACC-62 (melanoma) and HT29 (colon cancer) cell lines using MTT, a colorimetric tetrazolium-based assay. Cytotoxic concentrations of the compounds that killed cells by 50% (CD50) with respect to untreated cell population, varied among the cell lines tested. CEM-SS was found to be the most sensitive cell line to methylgerambullin and bis-(methylthiomethyl)-disulphide with CD50 = 0.25 )µg/ml and 3.50 )µg/ml respectively. The cytotoxic effects exerted by both compounds on this cell line was studied from both morphological manner over 72 hours period. Microscopic observations, including inverted microscopy of live cultures, fluorescent microscopy of acridine orange-propidium iodide stained cultures, and scanning and transmission electron microscopy showed that both necrotic and apoptotic death occurred in meiliylgerambullinand bis-(methylthiomethyl)-disulphide-treated cell populations, based on morphological criteria. From agarose gel electrophoresis and quantitative analyses of intemucleosomal cleavage, treatments with these compounds at their respective CD50 doses did not yield random or multiple of 180-200 bp DNA fragmentation which often associated with necrotic and apoptotic deaths respectively. Such observation may simply owe to the fact that the percentage of apoptosis and necrosis events were fairly low as quantified after acridine orangepropidium iodide staining, or may also suggest the involvement of sulphur residue in methylgerambullin and bis-(methylthiomethyl)-disulphide which act as an antioxidant, thus protecting DNA degradation from occuring. Flow cytometric analyses based on annexin V-FITC (fluorescein isothiocynate) binding to the phosphatidylserines residue which was translocated from the inner to the outer leaflet of the plasma membrane showed that the onset of apoptosis in both methylgerambullin- and bis-(methylthiomethyl)-disulphide-treated population was at 6 hours exposure. Both methylgerambullin and bis-(methylthiomethyl)disulphide induced GO/G1 arrest up to 48 hours and 24 hours respectively followed by arrest in the subsequent S phase

    Application of machine learning to support self-management of asthma with mHealth

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    While there have been several efforts to use mHealth technologies to support asthma management, none so far offer personalised algorithms that can provide real-time feedback and tailored advice to patients based on their monitoring. This work employed a publicly available mHealth dataset, the Asthma Mobile Health Study (AMHS), and applied machine learning techniques to develop early warning algorithms to enhance asthma self-management. The AMHS consisted of longitudinal data from 5,875 patients, including 13,614 weekly surveys and 75,795 daily surveys. We applied several well-known supervised learning algorithms (classification) to differentiate stable and unstable periods and found that both logistic regression and naïve Bayes-based classifiers provided high accuracy (AUC > 0.87). We found features related to the use of quick-relief puffs, night symptoms, frequency of data entry, and day symptoms (in descending order of importance) as the most useful features to detect early evidence of loss of control. We found no additional value of using peak flow readings to improve population level early warning algorithms

    Stormwater Infrastructure Optimization on Conjunctive Improvements

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    The studied drainage system is located in the downtown of the City of Newport News, in a basin known as Anderson Park. The drainage system collects and conveys rainfall runoffs to the system outfall located at the shoreline of the Hampton Roads body of water, which is located south of the study area. The aim of this study is to analyze the area\u27s drainage system, determine maximum capacities, identify system deficiencies and generate the most possible, practical and economical solution for fixing the system deficiencies. After collecting all of required data, the drainage system was modeled and calibrated using the recorded rainfall data of October 9t11, 2013 and the measured watermark elevations at the selected junctions. The methods used for estimating probability distributions of the recorded rainfall frequency were Hazen, Weibull, Gringorten, and Sevruk & Geiger; and the Weibull method was used for the system analysis. However, the City\u27s requirement is for all drainage systems, residential and commercial, to handle NOAA\u27s 10-yr storm, which is the accumulation of 5 to 6 inches in 24-hour duration. For the purpose of this study to include loss analysis, storm return periods from 10- to 500-yrs were listed and ranked to their rainfall depths and the associated damage values. To determine the severe cost of the drainage system improvement, the system was subjected to Weibull 100-yr storm. This study tried to improve the drainage system by increasing pipe sizes to the minimum possible diameter that the system can handle the Weibull 10-yr storm flow without experiencing flooding anywhere along the system pipeline. For this purpose, the technique of optimization was utilized to perform pipe-area changes and to keep HGLs at or below structure rim elevations. Four improvement case scenarios were created at the targeted area along the drainage system where all branches merge together. Finally, the selected case scenario 4 at $1,379,500 appeared to be the most practical, economical and optimal case scenario for this area\u27s system improvements
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