3,256 research outputs found
Meson production in two-photon interactions at energies available at CERN Large Hadron Collider
The meson production cross sections are estimated considering photon-photon
interactions in hadron - hadron collisions at CERN LHC energies. We consider a
large number of mesons with photon-photon partial decay width well constrained
by the experiment and some mesons which are currently considered as hadronic
molecule and glueball candidates. Our results demonstrate that the experimental
analysis of these states is feasible at CERN - LHC.Comment: 5 pages, 1 figure, 4 tables. Version published in Physical Review
Effects of ursodeoxycholic acid on synthesis of cholesterol and bile acids in healthy subjects
Background/Aims: Ursodeoxycholic acid ( UDCA) decreases biliary secretion of cholesterol and is therefore used for the dissolution of cholesterol gallstones. It remains unclear whether these changes in biliary cholesterol excretion are associated with changes in cholesterol synthesis and bile acid synthesis. We therefore studied the activities of rate-limiting enzymes of cholesterol synthesis and bile acid synthesis, 3-hydroxy-3-methyl-glutarylcoenzyme A reductase and cholesterol 7alpha-hydroxylase, respectively, in normal subjects during UDCA feeding. Methods: UDCA was given to 8 healthy volunteers ( 5 men, 3 women; age 24-44 years) in a single dose of 10-15 mg/kg body weight for 40 days. Before and during ( days 3, 5, 10, 20, 30 and 40) UDCA treatment, urinary excretion of mevalonic acid and serum concentrations of 7alpha-hydroxy-4-cholesten-3-one (7alpha-HCO) were determined as markers of cholesterol and bile acid synthesis, respectively. The Wilcoxon signed rank test and Spearman's rank correlation coefficient were used for statistical analysis. Results: Cholesterol synthesis and serum lipid concentrations remained unchanged during UDCA treatment for 40 days. However, synthesis of bile acids increased during long-term treatment with UDCA as reflected by an increase in 7alpha-HCO serum concentrations from 39.7 +/- 21.3 ng/ml (median 32.8 ng/ml) before treatment to 64.0 +/- 30.4 ng/ml (median 77.5 ng/ml) at days 30-40 of UDCA treatment ( p < 0.05). Conclusions: UDCA treatment does not affect cholesterol synthesis in the liver, but does increase bile acid synthesis after prolonged treatment. This may represent a compensatory change following decreased absorption of endogenous bile acids as observed with UDCA therapy
Coulomb Corrections for Coherent Electroproduction of Vector Mesons: Eikonal Approximation
Virtual radiative corrections due to the long range Coulomb forces of heavy
nuclei with charge Z may lead to sizeable corrections to the Born cross section
usually used for lepton-nucleus scattering processes. An introduction and
presentation of the most important issues of the eikonal approximation is
given. We present calculations for forward electroproduction production of rho
mesons in a framework suggested by the VDM (vector dominance model), using the
eikonal approximation. It turns out that Coulomb corrections may become
relatively large. Some minor errors in the literature are corrected.Comment: 14 pages, 6 figures, published versio
Radion production in exclusive processes at CERN LHC
In the Randall-Sundrum (RS) scenario the compactification radius of the extra
dimension is stabilized by the radion, which is a scalar field lighter than the
graviton Kaluza-Klein states. It implies that the detection of the radion will
be the first signature of the stabilized RS model. In this paper we study the
exclusive production of the radion in electromagnetic and diffractive hadron -
hadron collisions at the LHC. Our results demonstrate that the diffractive
production of radion is dominant and should be feasible of study at CERN LHC.Comment: 6 pages, 3 figures, 1 tabl
Raman cooling and heating of two trapped Ba+ ions
We study cooling of the collective vibrational motion of two 138Ba+ ions
confined in an electrodynamic trap and irradiated with laser light close to the
resonances S_1/2-P_1/2 (493 nm) and P_1/2-D_3/2 (650 nm). The motional state of
the ions is monitored by a spatially resolving photo multiplier. Depending on
detuning and intensity of the cooling lasers, macroscopically different
motional states corresponding to different ion temperatures are observed. We
also derive the ions' temperature from detailed analytical calculations of
laser cooling taking into account the Zeeman structure of the energy levels
involved. The observed motional states perfectly match the calculated
temperatures. Significant heating is observed in the vicinity of the dark
resonances of the Zeeman-split S_1/2-D_3/2 Raman transitions. Here two-photon
processes dominate the interaction between lasers and ions. Parameter regimes
of laser light are identified that imply most efficient laser cooling.Comment: 8 pages, 5 figure
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Photoreversible interconversion of a phytochrome photosensory module in the crystalline state.
A major barrier to defining the structural intermediates that arise during the reversible photointerconversion of phytochromes between their biologically inactive and active states has been the lack of crystals that faithfully undergo this transition within the crystal lattice. Here, we describe a crystalline form of the cyclic GMP phosphodiesterases/adenylyl cyclase/FhlA (GAF) domain from the cyanobacteriochrome PixJ in Thermosynechococcus elongatus assembled with phycocyanobilin that permits reversible photoconversion between the blue light-absorbing Pb and green light-absorbing Pg states, as well as thermal reversion of Pg back to Pb. The X-ray crystallographic structure of Pb matches previous models, including autocatalytic conversion of phycocyanobilin to phycoviolobilin upon binding and its tandem thioether linkage to the GAF domain. Cryocrystallography at 150 K, which compared diffraction data from a single crystal as Pb or after irradiation with blue light, detected photoconversion product(s) based on Fobs - Fobs difference maps that were consistent with rotation of the bonds connecting pyrrole rings C and D. Further spectroscopic analyses showed that phycoviolobilin is susceptible to X-ray radiation damage, especially as Pg, during single-crystal X-ray diffraction analyses, which could complicate fine mapping of the various intermediate states. Fortunately, we found that PixJ crystals are amenable to serial femtosecond crystallography (SFX) analyses using X-ray free-electron lasers (XFELs). As proof of principle, we solved by room temperature SFX the GAF domain structure of Pb to 1.55-Ă… resolution, which was strongly congruent with synchrotron-based models. Analysis of these crystals by SFX should now enable structural characterization of the early events that drive phytochrome photoconversion
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