Correlation between transition temperature, in-plane copper-oxygen bond length, and tilt/buckling of the CuO2 plane in cuprate superconductors

Correlation among transition temperature, in-plane Cu-O bond length, and tilt/buckling in cuprate superconductors were examined in detail. As for cuprates with a single CuO_2 layer, tilt structure was observed in the region, whose in-plane Cu-O length was 1.906-1.926 Å, and that the tilt structure drastically suppressed superconductivity. As for cuprates with double CuO_2 layers, all the compounds had buckling distortion in a CuO_5 pyramid. The degree of distortion was determined only by a kind of cation between the two facing CuO_5 pyramids, that is, calcium or yttrium. A higher transition temperature was obtained for a copper oxide with having larger Cu-O length and smaller buckling degree. A common feature of layered cuprates was the existence of three major classes distinguished by the cations Ba^, Sr^, and Ln^ occupying the 9-coordination sites

A Computational Predictor of Human Episodic Memory Based on a Theta Phase Precession Network

In the rodent hippocampus, a phase precession phenomena of place cell firing with the local field potential (LFP) theta is called “theta phase precession” and is considered to contribute to memory formation with spike time dependent plasticity (STDP). On the other hand, in the primate hippocampus, the existence of theta phase precession is unclear. Our computational studies have demonstrated that theta phase precession dynamics could contribute to primate–hippocampal dependent memory formation, such as object–place association memory. In this paper, we evaluate human theta phase precession by using a theory–experiment combined analysis. Human memory recall of object–place associations was analyzed by an individual hippocampal network simulated by theta phase precession dynamics of human eye movement and EEG data during memory encoding. It was found that the computational recall of the resultant network is significantly correlated with human memory recall performance, while other computational predictors without theta phase precession are not significantly correlated with subsequent memory recall. Moreover the correlation is larger than the correlation between human recall and traditional experimental predictors. These results indicate that theta phase precession dynamics are necessary for the better prediction of human recall performance with eye movement and EEG data. In this analysis, theta phase precession dynamics appear useful for the extraction of memory-dependent components from the spatio–temporal pattern of eye movement and EEG data as an associative network. Theta phase precession may be a common neural dynamic between rodents and humans for the formation of environmental memories

コウボクによるPorphyromonas gingivalisのメチルメルカプタン産生の抑制メカニズムの解明に関する研究

内容の要旨, 審査の要旨広島大学(Hiroshima University)博士(歯学)Doctor of Philosophy in Dental Sciencedoctora

現代日本における既婚女性の労働生活 : 広島県を事例として

内容の要約広島大学(Hiroshima University)博士(学術)Philosophydoctora

Rejuvenecimento da marca Banco do Brasil com o marketing esportivo : vôlei

Orientador : Zaki Akel SobrinhoMonografia (especialização) - Universidade Federal do Paraná, Curso de Especialização em Marketing EmpresarialInclui referênciasResumo: Este "case" mostra o projeto desenvolvido, a partir de 1991, para rejuvenescer a imagem e a clientela do Banco do Brasil. Este projeto que está, ainda, em curso, mas que já pode ser consagrado com uma das mais bem sucedidas incursões mercadológica do País, tem como instrumento a promoção de eventos esportivos. Um marketing feito de gente para gente, com muita emoção, coração e muita sensibilidade, assim como todo o esporte. O BB estabeleceu políticas e estratégias de relacionamento e negócios para com o público jovem, lançando serviços diferenciados ao segmento jovem, focando sua atuação na fidelização deste público. A utilização das ferramentas do composto de marketing para agregar valor à marca é a estratégia principal do marketing esportivo adotado pelo BB .. O sucesso do case é uma resultante do ato de estar sempre "em conquista", eternamente, sem parar, superando-se continuamente, todo dia, segundo a segund

Encapsulation of mRNA into Artificial Viral Capsids via Hybridization of a β-Annulus-dT20 Conjugate and the Poly(A) Tail of mRNA

Messenger RNA (mRNA) drugs have attracted considerable attention as promising tools with many therapeutic applications. The efficient delivery of mRNA drugs using non-viral materials is currently being explored. We demonstrate a novel concept where mCherry mRNA bearing a poly(A) tail is encapsulated into capsids co-assembled from viral β-annulus peptides bearing a 20-mer oligothymine (dT20) at the N-terminus and unmodified peptides via hybridization of dT20 and poly(A). Dynamic light scattering measurements and transmission electron microscopy images of the mRNA-encapsulated capsids show the formation of spherical assemblies of approximately 50 nm. The encapsulated mRNA shows remarkable ribonuclease resistance. Further, modification by a cell-penetrating peptide (His16) on the capsid enables the intracellular expression of mCherry of encapsulated mRNA